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Inside a mini-brain (with eyes?) lab - Science unscripted 

DW Podcasts
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If a free-floating brain could feel pain or 'wake up,' how would we know? That's an important ethical question - and it's one we need to ask more often as labs around the world create new organoids, or miniature human organs. To answer it we talked to Jay Gopalakrishnan at his 'mini brain' lab for centrosome and cytoskeleton biology in Düsseldorf, Germany.
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#brains #organoids #ethics #Germany #India
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2 окт 2024

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Комментарии : 136   
@dw_podcasts
@dw_podcasts 2 года назад
Big thanks to Jay and his team at the Heinrich Heine University in Düsseldorf for letting us inside their (soon-to-be-former) labs!
@havesomerubicon6097
@havesomerubicon6097 2 года назад
wtf is with the fisheye effect
@dw_podcasts
@dw_podcasts 2 года назад
13:45 ⏯️
@notprovided1131
@notprovided1131 Год назад
​@@dw_podcasts It makes the video much worse
@Garylincoln789
@Garylincoln789 Год назад
I guess to imagine how the mini brain sees the world.
@BritishEngineer
@BritishEngineer Год назад
There’s no scientific evidence that those eyes see using a 360° field of vision. I see no relevance nor justification to fisheye being added other than the camera crew having access to 360° camera and wanting their moneys worth. qwq lol
@kuryakin2483
@kuryakin2483 Год назад
@@dw_podcasts I feel like instead of budgeting for a second camera (and another camera angle) they went for this 360. Then they got too stoned in the edit bay.
@johncrowcc
@johncrowcc 2 года назад
Aww sweet. Man made horrors beyond my comprehension.
@eigenman2571
@eigenman2571 2 года назад
The editor’s having too much fun with the 360 camera heh
@Plumberboi91
@Plumberboi91 Год назад
Anyone else find it kind of unsettling that the first thing these tiny brains want to do is grow eyes to see what's going on?
@alarmy5211
@alarmy5211 Год назад
well what else am i… the tiny brains. what are they supposed to do? i wouldn’t know, i’m not a tiny brain. i’m not. i’m not a little brain in a lab.
@Waltyworld
@Waltyworld Год назад
Lol😅😅😅 what if there conscience
@alarmy5211
@alarmy5211 11 месяцев назад
@@vitmartobby5644 a small little brain like that couldn’t do much except cry for help online after finding a way to brain hack into a computer snd learn english. i wouldn’t know though
@Prsop554
@Prsop554 10 месяцев назад
Perception is a quintessential pillar of life, without perception stimulus would be meaningless, you wouldn't be able to differentiate food from adversary, etc.
@Pearlylove
@Pearlylove 9 месяцев назад
100%. WHY do they put in just eye cells? They try different ways to make conscious brain. Like they got brain cells to play ping pong- here we have to use our brain, intuition, and gut feeling, and not accept being silenced bc “you don’t understand science”. What happens when they put this into chips in large computer systems? We have no idea if this really was the reason for ChatGBT breakthrough. HOW will they eventually break this to us? Sooner or later they will have to.
@paktmtv3963
@paktmtv3963 2 года назад
That fish eye camera should not be used
@massamando2186
@massamando2186 2 года назад
Really appreciate your effort, the conceptual twist with the camera and all. It just would have been great if you came a bit more prepared - feels like you missed the opportunity to ask some more interesting questions instead of "do you consider yourself normal?" and "what happens if I eat it?"
@dw_podcasts
@dw_podcasts 2 года назад
Hi Massa - those were definitely the goofiest questions we asked, but they're also questions we saw real people posing when this research was first published. And we think it's fair to try to answer those, even if they're not you're looking for, since for some people they're as important, or more important, than the hard biology itself (which we got into later).That said, we'd love to hear what you would have asked Jay and his team if you don't mind posting a question or two here? There's a good chance we'll see him again, and we'd be happy to ask on your behalf.
@Pearlylove
@Pearlylove 9 месяцев назад
See in a bigger picture. 🙏🏻GET THOSE DEBATES OUT FOR ALL TO SEE. Closely connected to AI, (OpenAI?), “brain-chips”, neuroscience, Brain organoids, consciousness, ethics, G5 arms race, NPUs, bio-cybernetic cerebral organoids, Synthetic Biological Intelligences, Antagomirs etc.
@jianju4916
@jianju4916 2 месяца назад
@@dw_podcasts Yes, and you forgot my most pressing question: does it poop?
@dw_podcasts
@dw_podcasts 2 месяца назад
@@jianju4916 😆
@xMariki
@xMariki 2 года назад
I get motion sickness from this ^^' The content is super intressting but this fisheye is too much
@dw_podcasts
@dw_podcasts 2 года назад
Noted!
@sheenajae
@sheenajae 2 года назад
Same. Had to stop watching 😞
@christianagnick6739
@christianagnick6739 2 года назад
Ah sweet! Man made horrors beyond my comprehension
@Ghostneedle1
@Ghostneedle1 2 года назад
The audio that they edited in is so loud and annoying. I think it gets in the way of trying to watch the report. Very interesting though.
@Kimchiipancakes
@Kimchiipancakes Год назад
You've made it here, you have more knowledge now. You could have ended up anywhere else But now you know something very important and put yourself on a path of thought ✨️
@jzeerod
@jzeerod Год назад
so funny there was a viddy idk who made it about a brain with eyes and core in a lab nutrient tank. he got scrubbed down, talked to, he watched. got hooked up to electrodes and yelled at by frustrated leader for not being "smart or intelligent" but he was just sad and dejected with his lot in life, then he realized he was number 19 or something. a short but very funny little skit i watched this and it was like watching a parody of that skit.
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
well, isnt that impressive how well somebody predicted the future someone is living and you are not even out there, facing the science, instead leaving some comments about a Skit that didnt impress you
@petevenuti7355
@petevenuti7355 Год назад
Oh, and I did get the purpose of the 360 cam, putting you, the viewer, in the point of view of the organoid.. also the extra stimulation switching back and forth provides might be good for ADHD viewers to maintain interest even if it's overwhelming for just as many... After everything else is said, It still definitely serves a fitting creepy aesthetic within the context of this specific video.
@JoBot__
@JoBot__ Год назад
People like me who get overstimulated by it can just look away from the screen occasionally. I spent maybe ~50% of the video looking away from the screen. 😅
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
@@JoBot__ i love that im not alone fighting that fight, it was pure adhd joy trip, there is just 100 comms here, and all hate on my fav feature, no worries, im a good bot too, i can multitask myself to the oblivion so everyone will know how much i hate yall haters for telling those extremely talanted folks what tot do.. they could me so much more creative if not your constant guidance... the fate of those who giver a fuck about you nasty little gremlins
@kirianismaelsanchez9606
@kirianismaelsanchez9606 Год назад
Please, not that fisheye
@hahahahahohohoho5085
@hahahahahohohoho5085 Год назад
would you stop it with those juvenile camera effects already? made me turn off the video, so obnoxious
@yoyo9655
@yoyo9655 2 года назад
Lol these goofs need to study bio a bit more to ask interesting questions but other than that its a great production :)
@jianju4916
@jianju4916 2 месяца назад
I like how he just claims it doesn't have consciousness. I would like to know how they can prove that. A human mind at the earliest stages of development will not have the same shape as a mature brain, but parts of the brain involved directly in consciousness could still be there in a different form. They are screwing around with what makes a person a person - their mind.
@sheiladouglas5456
@sheiladouglas5456 2 года назад
I enjoyed your interview on brain organoids but you missed one of the most important aspects of this new technology in that it replaces the real pain and suffering that millions of actually sentient lab animals experience every day or year from experimentation for 'the greater good' . You guys are very astute but you missed the boat on this one. Tom Reimchen, Dep't of Biology, University of Victoria.
@dw_podcasts
@dw_podcasts 2 года назад
Hi Tom, we actually did ask this question of Jay but the audio was unusable (due to construction noise outside the window). Here is the transcription: CONOR: So, at the very least you're saving some animals out there from having to undergo experiments? JAY: Definitely! Not only are we saving the animal models in this case, but we are trying to understand the human-specific mechanisms that these animal models may not be able to offer to us. We are speaking about human materials. And we are able to generate hundreds of organoids, not just one or two, so we have a better understanding of the biology, of the statistics, how many data points are validating our findings. We don’t have to sacrifice animals for this research. Animal testing is indeed important to understand better the biology in a living organism, but in my opinion it is better in our experiments to study the human-specific biology using human-derived materials.
@KasunWijesekara
@KasunWijesekara Месяц назад
i cant belive you guys sent these two clowns to something so interesting and ground breaking. This is worse than the US senete asking questions from Zuckerberg. what the hell guys
@KasunWijesekara
@KasunWijesekara Месяц назад
bro is asking whether he can eat a bunch of cells and whether it does something to him. Bro it goes to ur stomach and it gets broken down, you'll have to find a new way to find new brain cells.
@adrianhall210
@adrianhall210 2 года назад
I’ve been listening to your show on CBC radio every Sunday morning at 4:30am , for quite some time now and I love your show guys. Thank you for quirky content, makes me laugh while I’m waking up.👍🏻😂
@dw_podcasts
@dw_podcasts 2 года назад
4:30 a.m. Canada crew, represent! Thanks for coming over here to say hello, Adrian, you made our day 😀
@thecraig1620
@thecraig1620 Год назад
Omg pac man was from future
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
fr
@紺野-純子
@紺野-純子 2 года назад
2k views what?? this shit is interesting how could it get this so little views....
@readycon_live
@readycon_live Год назад
Hey DW, would it be okay if we used this video as a footage for our speakers at a conference for secondary school students? :)
@dw_podcasts
@dw_podcasts Год назад
👍🤝 Course - feel free to flash our email so students can give feedback, would be interesting to hear their perspective! 📧 su@dw.com 📧 Lepo pozdravljeni!
@readycon_live
@readycon_live Год назад
@@dw_podcasts Perfect! Thank you very much, will do. :)
@noahway13
@noahway13 Год назад
Most unnecessary words in the human language. "Let us know what you think in the comments'.
@ducttapetech9885
@ducttapetech9885 6 месяцев назад
That fish eye effect is way overdone here making the video unwatchable.
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
well, you dont like it, I do :)
@Smoshylife
@Smoshylife 2 года назад
“Will I be smarter if I eat them?” Bruh ask better questions
@ydnas5309
@ydnas5309 2 года назад
Oh damn those mini brain have consciousness
@catpoke9557
@catpoke9557 Год назад
To some degree I suppose they do
@yewbranch
@yewbranch 2 года назад
I have to wonder how much this could scale. With an array of a few million of these hooked up to electrodes, maybe a parallelization-based brain of human (or >human) capacity could be built.
@vke6077
@vke6077 Год назад
I heard somewhere however that the human brain is more like a cellphone in terms of computing power but has a lot of memory and can paralellise processes very well, thus its speed.
@jzeerod
@jzeerod Год назад
the only limit to lab grown meat was that it couldnt get oxygen into the core so it could only grow so large, now they formed lattice work of veins and a pump to transport oxygen bearing protoplasma into the inner muscle, whatever however im not sure, but now they can grow larger pieces of muscle with this method and keep it alive indefinitely provided of pumping action, make a heart, you have a brain, grow a chicken without a womb, imagine the technical progress one could make. you could grow your little thing around an organoid linked to a quantum processor fiddling with them every once in a while because they are within a transparent growth chamber/artificial womb. you could make a creature with smarts that you could control completely.
@musiicxlover93
@musiicxlover93 9 месяцев назад
Fire whoever produced this video. Dialogue/fisheye overuse was embarrassing
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
your comment is emberassing sweetie, you are a hater,but dont worry, you will grow out of it, plenty of people before you did, wellcome to the internet. nobody likes toxic comments, you will need to remember that your digital footprint lets plenty room for consequenses
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
nice concert btw
@musiicxlover93
@musiicxlover93 3 месяца назад
@@SillyTech-gf3mi I don't give a shit
@Guckeezy
@Guckeezy Год назад
This 360 camera is horrible. Get rid of it.
@Guckeezy
@Guckeezy Год назад
Like it’s not edgy at all.
@JoBot__
@JoBot__ Год назад
@@Guckeezy Who said it was supposed to be edgy? If you had even watched the video you'd know it was there for a purpose, that being to give you a perspective of what it might be like to be one of those brain organoids.
@joeyedwards6001
@joeyedwards6001 Год назад
They made these from 173 these but quickly scaled up to 800,000 mini brains (perhaps many million now).. It's already crossing unethical proportions. We have no idea if these living organisms have souls, pain, or consciousness.
@Smoshylife
@Smoshylife Год назад
There are no sensory nerves on the brain itself, brain way too small to have consciousness
@notprovided1131
@notprovided1131 Год назад
Modern witchcraft
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
the best kind
@neronamae
@neronamae 2 года назад
I'm your 37th subscriber 😚
@dw_podcasts
@dw_podcasts 2 года назад
Hi Nerona, one day no one will believe that you were number 37 on this channel. Our suggestion: Take a screenshot of your comment, print it, and have it professionally framed - and then create a digital non-fungible token as well. Anything less would be a grave error...
@neronamae
@neronamae 2 года назад
Well, I've already screenshot the proof that I'm your 37th subscriber (I screenshotted it before I subscribed to this channel). Tomorrow I'll print my screenshot that proves that I'm your 37th subscriber. I'll put it inside the frame and display it on our front door so that if someone asks me what my biggest achievement in life is, I'll tell them to "look at the front door of ours." You'll see my biggest achievement in life and I'm the 37th subscriber of DW Science Unscripted, the most famous podcast channel in the whole universe, and they will be proud of me". LMAO. You know, I'm a psychic, and I can feel that you'll hit millions of subscribers before 2022 ends. I tried to find your Instagram, but I couldn't find it. Do you guys have Instagram? By the way, I'm just kidding that I'm a psychic. If you reach millions of subscribers before the end of 2022, you'll give me $1,000. LMAO! Deal? just kidding.
@dw_podcasts
@dw_podcasts 2 года назад
We liked this comment so much that we printed it and put it on a wall here at DW
@neronamae
@neronamae 2 года назад
@@dw_podcasts WHAHHAHAHAHAHAHAHAHAHHAHAHAHAHAHAHAHGHA 💀💀💀💀
@neronamae
@neronamae 2 года назад
@@dw_podcasts you made my day 💀💀💀
@gimbatul9761
@gimbatul9761 2 года назад
Surprising that a channel from a major news org has only 145 subs after over a month of regular uploads.
@dw_podcasts
@dw_podcasts 2 года назад
It's all good Gimbatul - we're going for the slow burn 😉🔥🚀
@foxkillingtime
@foxkillingtime Год назад
Black mirror episode on the way.
@gbowman9429
@gbowman9429 Год назад
Soylent Green IS PEOPLE!!!!
@KasunWijesekara
@KasunWijesekara Месяц назад
im sorry for the rant im drunk
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
fellas, the way you broke the tension at the end, it was majestic, im a big fun of such narativistic twistits thats what unscripted does to one, our brain is the best narative generator. however, i would advice you, if you wanna know about this more, its a whole field, ... oh wait a minute, its a a two years old video, only 100 comments huh ill beback with a follow up :D
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
oh, unfortunately i dont see any progress on that regard, well id suggest a part two, this time visit The Thought Emporium, he will have plenty more to say , as his cells learn to play doom as you read this comment
@tbonates123
@tbonates123 3 месяца назад
Important content. But, the 360 camera and the editing are a big turn off. Makes it for an unpleasant view. The fake conversation is also annoying.
@dw_podcasts
@dw_podcasts 3 месяца назад
We dropped the 360 camera after this video, but the conversation was a real one - not sure what you mean there? - Conor
@specialk7663
@specialk7663 2 месяца назад
Reminds me of Ursulas' garden of merfolk 😬
@xVenez
@xVenez 3 месяца назад
the editing is bad and the 360 camera thing is just annoying
@KasunWijesekara
@KasunWijesekara Месяц назад
who ever decided to do this with a fish eye lense, bro go have a mediocre day.
@utkutk22
@utkutk22 6 дней назад
I’d like to see him in a real interview
@simbasims1679
@simbasims1679 2 месяца назад
These two should not have been the ones to interview this guy.
@egg979
@egg979 Год назад
The missing link in AI …
@leonelnm963
@leonelnm963 6 дней назад
Interesting.
@beggarslexicon7649
@beggarslexicon7649 Год назад
Hate the awful fish-eye effects. Unwatchable. Was it a new toy?
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
yeah, ever played with it? i guess not , so dont dare ruining the fun for those fellas, who tf are you to tell them what to do? you are just a randonm ass youtube user, know your place
@noahway13
@noahway13 Год назад
I'd like to implant these in one of those cute small monkeys and have a pet that can use the restroom, clean the house, do laundry and fold clothes, can do her hair and look damn cute in a tiny French maid uniform, fix a hot, soapy bath, and be super excited when I get home.
@okaylikeiguessso7213
@okaylikeiguessso7213 2 месяца назад
Horrible questions
@nickatredbox
@nickatredbox 6 месяцев назад
Enough with the fisheye lens
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
NOPE , its my favorite effect, screw you , if you dont like it, just dont look at it, you can still hear it, its not your job to dictate what artistic choice was unessesary. do you go to a gallery and mock the artists? thats a fun life you have
@hansenkoh5372
@hansenkoh5372 2 месяца назад
Too much fish eye be serious pls.
@dw_podcasts
@dw_podcasts 2 месяца назад
Thank you for your feedback.
@planetballuniverse2108
@planetballuniverse2108 6 месяцев назад
How do those things eat
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
they are cells, they are swiming in a nutrious puddle and absorb the yummi folded strings of mass thats been provided to them by HIM
@gbowman9429
@gbowman9429 Год назад
tee hee... he says there is no way they can have or develop (evolve) consciousness, "he thinks". Hmmm, the doctor thinks therefore he is the authority on these brains, but the brain's don't, he think's. Induce pain? Mad science.
@catpoke9557
@catpoke9557 Год назад
They are already conscious to some extent. Anything capable of thinking to any capacity has some degree of consciousness. It's just very small. So if these really are mini brains like they say, they must be capable of very minor and simple thought, less than even an insect though probably
@petevenuti7355
@petevenuti7355 Год назад
They're asking him if *_he's_* normal, and then they asked if they could eat the brains‽😅
@Smoshylife
@Smoshylife 2 года назад
Are you vegan? If you’re not, you have no room to discredit this
@mathewmcgill6266
@mathewmcgill6266 Год назад
I find the optics and sound effects extremely annoying. Do you consider the substance of this video so doldrum that you need to add all this distraction?
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
its the delirium that science gets, if you dont like it, its not for you then, leave
@beckhaglund
@beckhaglund 9 месяцев назад
The music was too much
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
well, then you didnt vibe with the humor, happens
@truth_powers
@truth_powers Год назад
good video but jesus all the music was abnoxious
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
im sorry bro, perhaps i would even try arguing with you , but trust me with your thumbnails you have no say, get more creative, you have so many artistic potential you can furfill instead of just sticking ur face everywher, you will notice a significant boost in interest, trust me
@chailyncorbin4651
@chailyncorbin4651 2 года назад
As an expat in Germany, I love listening to your podcasts, and now your videos too, especially this one in 360! But yeah growing brains is Wahnsinn!
@dw_podcasts
@dw_podcasts 2 года назад
Hi Chailyn, welcome to the channel! 🤝🥨🍻
@YEWCHENGYINMoe
@YEWCHENGYINMoe Год назад
Eye
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
rip
@mrnobody.4069
@mrnobody.4069 Год назад
We should use those tiny organs to make a really tiny human that we can keep as a pet!
@brunitoforrester
@brunitoforrester Год назад
Nobody said ever that'd be uncanny as hell
@mrnobody.4069
@mrnobody.4069 Год назад
@@brunitoforrester I didn't say that!?🤣
@catpoke9557
@catpoke9557 Год назад
I can think of absolutely zero potentially unethical consequences of this idea
@mrnobody.4069
@mrnobody.4069 Год назад
@@catpoke9557 Its a joke
@catpoke9557
@catpoke9557 Год назад
@@mrnobody.4069 so is my comment
@shailesh6936
@shailesh6936 2 года назад
Well it's one of the nearest thing to sci-fi like stuff that means there must be some really crazy people working working there and u know what is synonymous to crazy smart mind ....Indian mind😅😅 fuck m overproud🤣🤣🤣deal with it😅
@wdiribarne
@wdiribarne 6 месяцев назад
👎awful, unserious skit
@SillyTech-gf3mi
@SillyTech-gf3mi 3 месяца назад
awful, unserious commenter, should not be taken seriously. grop up dude. you can express yourself better on the internet. i reccomend you trying , youll notice that people will be invested in you if youll get more elaborative about your stuff, and will actually have suggestions instead of unreasonable toxic hate you and people before you ... and unfortunately after will keep spreading but not if you will wake up and decide to mature out of it, to actually use the internet with its true intention. to exchange data. your comment fr just wastes space on big corporation's server dont you feel litlee ashamed leaving it there, most likely knowing nobody would notice, and yet, here we are, you are cursed by alghoritms my friend, as i do not know what will come afte this comment, but im sure, one day ill come there with marshmellow and some friends, and well have a lot of fun :)
@ydnas5309
@ydnas5309 2 года назад
Same thing as cloning..unethical
@pezequilibradohace5anos538
@pezequilibradohace5anos538 2 года назад
Nope, stfu, it’s interesting and the brains still aren’t capable of having a consciousness, and if it gets a consciousness then the scientists will take care of them, after all, its already possible to connect them to a computer
@matheussandbakk9959
@matheussandbakk9959 2 года назад
@@pezequilibradohace5anos538 Yeah not only aren't they advanced enough to have the ability for consciousness, but these braicells are grown from stem cells, just like most of your more advanced cells. Even then it's basically just cell replication just like all cells do. It'd be like saying it's unethical to scratch your arm as you're killing thousands of human skin cells or to extract cancer cells and grow them outside the body for research.
@NightmareCourtPictures
@NightmareCourtPictures Год назад
@@matheussandbakk9959 fair enough. Though I have a different perspective…that you should treat the small things as alive cause they are…even the skin you scratch off was once alive…and they should treated with respect as we do ourselves. Same thing with the inert components of your computer, rocks on earth…those are just as alive as we are and we should respect their existence not demean and destroy it
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