Is Coffee Associated With A Younger Biological Age?

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Papers referenced in the video:
Caffeinated and decaffeinated coffee consumption and risk of all-cause mortality: a dose-response meta-analysis of cohort studies
pubmed.ncbi.nl...
From cup to clock: exploring coffee’s role in slowing down biological aging
pubmed.ncbi.nl...

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4 окт 2024

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Комментарии : 145

@N_Ukestar-z9k 3 месяца назад

How big is a cup of coffee? How strong is the coffee? How much are the beans roasted? I drink a liter of strong coffee per day, i.e. 5 large cups.

@KoiRun50 3 месяца назад

You give the best food presentations.

@conqueragingordietrying123 3 месяца назад

Thanks @KoiRun50!

@eruiluvatar236 3 месяца назад

Gonna live forever then, there might be some blood in the coffee that runs through my veins.

@joemoya9743 3 месяца назад

Other studies show that causation may associated with Phenols and not necessarily coffee (or caffeine).

@shielddelan5991 3 месяца назад

Quercitin is included in coffee and is the reason for coffee beneifts.

@roblovegreen 3 месяца назад

Caffeine raises cortisol levels. Coffee is liquid stress. It also interferes with a persons sleep architecture hindering REM. If you drink coffee regularly and then remove it abruptly, see how you feel from the withdrawal. Coffee is an addiction and just like nicotine people try to find reasons that it’s good for you because they themselves are addicted..

@KasKade7 3 месяца назад

That's why I drink quality decaf. Still tastes great and getting all the benefits. But I feel even better without the caffeine.

@conqueragingordietrying123 3 месяца назад

I don't drink coffee-the published data is what it is Decaf was also significantly associated with reduced all-cause mortality risk (1st paper in the video)

@jamesgilmore8192 3 месяца назад

Yet the science on coffee all seems to indicate positive at 2-3 cups, that's not the case for smoking. Yes definitely monitor all biomarkers with and without coffee. And I would agree that for some people the caffeine is a problem that gets ignored.

@BR-hi6yt 3 месяца назад

I have given up all caffeine many times - all you get is a headache for about three days and its not a bad headache. Its easy to give up - but life is a bit more boring after.

@notanymore9471 3 месяца назад

I can’t say I’ve heard many if any arguments about smoking being good for you.

@jamesgilmore8192 3 месяца назад

Given coffee is known to improve liver health and reduce alt, ast, ggt, alp its good to see phenoage improve given two of those are in the calculator.

@abcdefgh4404 3 месяца назад

The difference between a medicine and poison is the amount you take it. Even water in excess will cause unbalance on metabolism.

@abcdefgh4404 3 месяца назад

Unfortunately you are correct

@peterz53 3 месяца назад

PS. besides black coffee only, would be good to parse out coffee drinkers who have varying amounts of total polyphenol intake. Like many single dietary interventions, wonder if the positive effect goes away in the context of a very good diet rich in polyphenols. In other words, does coffee add to health( by way of all cause mortality) if one is already eating very well. The things I can think of are increased autophagy (Pubmed, Quido Kroemer MD PhD researcher), positive liver effects (Pubmed), and countering calcium oxalate kidney stones (PubMed)

@abirhasankhan9327 3 месяца назад

Yes, a LOT of variables... However as for singular interventions, one study that has long intrigued me is the one where they saw that regular lifetime smokers had a lower chance of developing Parkinson's disease. Now we all know how utterly bad smoking is. Nevertheless, there WAS something in smoking cigerettes that contained SOMETHING that combatted Parkinson's in old age, whether that's the nicotine or the Monoamine oxidase inhitors present in the smoke is unknown. Still it baffles me to this day that even despite all the bad things in cigerette smoke, there was something that had a positive effect. Does that tell people who are at high risk of parkinsons to start smiking? No way! Unless they want to die of lung cancer first. Likewise, there could be some things in coffee as well... Too much coffee might be detrimental for, say, people with high blood pressure or cardiac diseases, but then again, we need to find out the main beneficial components...

@pimacanyon6208 3 месяца назад

@@abirhasankhan9327 nicotine is converted to nicotinic acid by the body. Nicotinic acid is Niacin, Vitamin B3. Why do you think they changed the name to Niacin? Don't want to have people thinking that there might be something in cigarette smoke that's actually beneficial! (I'm not a smoker and don't really like being around cigarette smoke. But I have a much greater dislike for deliberate attempts to hide the truth.)

@kiramiftari9486 3 месяца назад

@@abirhasankhan9327Smoking conventional cigarettes- def not! But using pure Nicotine - 💯 ;)

@peterz53 3 месяца назад

Thanks. Would be interesting to know if the study you cited parsed out black coffee vs adulterated. Will check. Switched to black about 12 years ago. 3 cups per day of which 2 are decaf. Flavors and quality varies a lot, like dark chocolate but not as extreme. All part of keeping a high polyphenol intake.

@antonystringfellow5152 3 месяца назад

At home, I always have the 2 together, ground coffee and 100% cocoa powder, in equal amounts. Not sure how healthy that combo is but it certainly tastes good!

@sultanal-rashed5702 3 месяца назад

Love this video! Your channel is fantastic.

@conqueragingordietrying123 3 месяца назад

Thanks @sultanal-rashed5702. Subscribe, and spread the word about the channel!

@jaimemarun2841 3 месяца назад

I take 10 lebanese coffee, stronger than espresso.. but the quantity is very small, may be is equivalent to 4 normal american coffee? How to know, may be the best metrics is caffeine?

@rredding 3 месяца назад

Probably it's about the amount of coffee beans that's used. I drank 6-8 cups semi-strong coffee per day, each with 9 grams ground coffee beans. I've recently had symptoms of overdose (I'm 65): * Eye migraine (that's weird flickering objects during a minute or so without headache) and more recently * Tremor in right index finger and area next to thumb during a few seconds every 30 minutes or so. I reduced my intake to two cups in the morning and symptoms are gone. I noticed longer sleep, from 5-6 hrs per night to 7-8. 30 years ago at work I was seated near a self service coffee machine with excellent filter coffee, my daily score was 15 cups without issues 😮

@jarichards99utube 3 месяца назад

Great Video... Thanks 👍 The only thing missing in these studies that I wonder about is Caffeinated vs DeCaf...?

@conqueragingordietrying123 3 месяца назад

Thanks @jarichards99utube. In the 1st study, decaf was similarly associated with a reduced ACM risk

@CyrilAndPriscilla 3 месяца назад

The thing is, the data can be interpreted in quite a different way. It is possible that there is a certain genotype that doesn't process caffeine the same way most people do--- say, a polymorphism in one of the liver detox pathways, like glycination, that slows down the detoxification of caffeine. These folks might naturally avoid coffee because it would make them feel more jittery and unwell than the normal user. It might be the case that that his detox gene is associated with a shorter lifespan.

@paulfiedler6820 3 месяца назад

It would also help to know the type of coffee and how it was prepared. My understanding is that whole bean coffee freshly ground and consumed black and without ANY additives provides the most nutrients. The freshness of the whole bean coffee is also important as it should be ground and consumed within a three month range to get the max bang for the buck. It’s hard for my to believe that something like a Folgers instant coffee would offer the same benefits as an organic Ethiopian whole bean coffee made in a French press. I worship coffee as a gift of the gods.

@LVArturs 3 месяца назад

Well, it can go both ways, since the more filtered and processed coffee definitely has less of the beneficial compounds, but might also have less deleterious ones which may also be present in a coffee bean.

@jamesgilmore8192 3 месяца назад

The addition of milk etc has been shown to make coffee less beneficial, but I don't remember the exact mechanism. There is debate about caffeine vs polyphenols, but both seem to help. If folgers has more of the relevant polyphenol that is beneficial then maybe it could be better....there isn't good data on specific compounds and what exactly they are doing.

@pimacanyon6208 3 месяца назад

@@jamesgilmore8192 I believe it's the milk protein that binds to some of the polyphenols, essentially nullifying them.

@arihaviv8510 3 месяца назад

Unfiltered coffee has been associated with higher ldl due to its diterpenes

@pimacanyon6208 3 месяца назад

@@arihaviv8510 which may or may not be problematic. the whole cholesterol field is fraught with controversy

@CaliforniaArchitect 3 месяца назад

Do people who drink less coffee drink more sugary soda? So, those who drink more coffee may be doing it as a substitute for a less healthy alternative.

@Pyriold 3 месяца назад

Yea this sounds plausible. Would be nice to see how water drinkers compare.

@drytropics 3 месяца назад

I've always been a big coffee drinker, and until my late 20s I even used to have a cup before bed. Now I have a strong brewed coffee for breakfast with a couple of spoons of added instant coffee, and my main meal replacement is a 750 ml triple strength full cream dairy iced coffee. It certainly helps keep me regular.

@againsteveryoneswill1923 2 месяца назад

Here are the details from the first study mentioned. Notice the words "might reduce" and "data suggesting that". Results: We included 21 cohort study articles (10 103 115 study participants and 240 303 deaths). We found a nonlinear association between coffee consumption and all-cause mortality (Pnonlinearity < 0.001). Compared with no or rare coffee consumption, with a consumption of 3 cups day-1 , the risk of all-cause mortality might reduce 13% (RR = 0.87; 95% confidence interval = 0.84-0.89). Conclusions: The findings of the present study provide quantitative data suggesting that coffee consumption plays a role in reducing the risk of all-cause mortality. Similar inverse associations are found for caffeinated coffee and decaffeinated coffee.

@glennwhitney1494 3 месяца назад

This is very interesting. Thanks.

@wichetleelamanit6195 3 месяца назад

I love to drink coffee and it is very good for me. I also drink many cups of tea. Both are wonderful for me. My blood test is great. Sometimes I have constipation from much tea. But milk kills the problem.

@hvvijuka 3 месяца назад

Coffee increase triglycerides, at least in my case

@arihaviv8510 3 месяца назад

Are you drinking unfiltered coffee? That's what is associated with higher ldl

@rredding 3 месяца назад

Higher LDL is not bad, seniors with higher LDL live longer. High Triglycerides is unhealthy.

@arihaviv8510 3 месяца назад

Well it's both @@rredding

@chris-lk4ml 3 месяца назад

Not in my case and Im drinking 2,5l coffee/day (decaf! ;))

@rredding 3 месяца назад

@@arihaviv8510 study yourself on LDL and perhaps you'll change your mind

@hvglaser 3 месяца назад

Could be that people don’t drink coffee are more likely to drink soda or other worse alternatives throughout the day.

@Nof1LongevityQuest 3 месяца назад

I assume you did this video because you are considering adding coffee into your dietary approach? Are there studies that compare coffee drinkers to tea drinkers for ACM?

@johnhancock5542 3 месяца назад

a similar report for tea would be fantastic

@conqueragingordietrying123 3 месяца назад

@@johnhancock5542 Already on the channel! ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-lq9YysNRjOQ.html

@conqueragingordietrying123 3 месяца назад

Hi Gail, yep, kicking the tires on coffee, mostly for its trigonelline content, but sometimes I focus on videos with a broader appeal, even if it doesn't apply to me... I'm not sure about coffee vs tea in a head-to-head matchup, but if those studies exist, I'm happy to take.a look!

@Nof1LongevityQuest 3 месяца назад

@@johnhancock5542 He did a similar report for tea: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-lq9YysNRjOQ.html

@Nof1LongevityQuest 3 месяца назад

@@conqueragingordietrying123 I want to say I found one a while back. If I can find it again, I'll share it here. As for me, I'm sticking with tea, but I'll be interested to see how the increased coffee/trigonelline works for you. I'd also love to see more data/studies on sleep.

@SuperAtheist 3 месяца назад

Just make sure to add lots of sugar and fat.

@rredding 3 месяца назад

Fat is okay, sugar (or other sweeteners) not.. 😅

@pimacanyon6208 3 месяца назад

great info. thanks. and thanks for pointing out the association versus causation question. Are people healthier because they drink more coffee? Or do healthier people tend to drink more coffee?

@peanutnutter1 3 месяца назад

Coffee drinkers are probably more likely to have a growth mindset, this too is correlated to good outcomes.

@willbrink 3 месяца назад

More coffee win!

@SladkaPritomnost 3 месяца назад

yeah, overdoing is better than not having a single none.

@karlint39 3 месяца назад

This sounds like a win-win. I love coffee, and if it has health benefits (i.e. improved all-cause mortality) what a bonus. I would be curious to know what the size of "a cup" of coffee is? In this research is one "cup" simply 8 oz? Are the cups standardized from one research study to the next?

@conqueragingordietrying123 3 месяца назад

Hi @karlint39, 8 oz = 1 cup, and generally yes. I prefer greater specificity (g or oz.) than cup sizes, which vary (as you're alluding) depending on the food or drink

@caffeinatedhuman4035 3 месяца назад

Interesting 45 drink coffee since 7.... There can be only one

@bridgepoc 3 месяца назад

Coffee is probably sort of like being caloric restricted without being caloric restricted. I often get anxious after drinking coffee until I eat and then I want more coffee.

@maestroharmony343 3 месяца назад

Measuring coffee in cups is so ambiguous. I use all kinds of cups for coffee. Also, what kind of coffee? This may make a big difference.

@HunterOfHalfLife 3 месяца назад

yeah, my cup is .5L

@quik4life 3 месяца назад

As someone like yourself, who doesn't drink coffee but rather only green tea (or matcha), the meta analysis is tempting to adjust my diet to start including 1-2 cups of decaffeinated coffee (I wouldn't want the added caffeine to effect my sleep). Michael: Do you have any plans of incorporating coffee into your diet, or are you just sticking with the green tea?

@conqueragingordietrying123 3 месяца назад

Hi @quik4life, decaf was also associated with a reduced ACM risk in the 1st study, so that could be a valid option. I'm not opposed to coffee, but I like green tea, so it's a binary choice for me. There's a different buzz that I get with coffee that I don't necessarily like, and it has after-effects (down) the next day, so sticking to green tea is a somewhat easy choice in my case.

@srenbro916 3 месяца назад

Is it the caffine or does decaf count?

@conqueragingordietrying123 3 месяца назад

Decaf was associated with a reduced ACM risk in the 1st study, too

@srenbro916 3 месяца назад

@@conqueragingordietrying123 thanks, that means a lot. Nice of you to answer so quickly.

@christiancrafoord 3 месяца назад

who drinks more than 1-2 cups? literally more dehydrating than alcohol!

@jpintero6330 3 месяца назад

Thanks for this interesting video! Was it filtered coffee? I have read that cafestol and kahweol are more concentrated in unfiltered coffee and raise LDL significantly. Have you ever looked into the subclinical long-term effects of fluoride in tea? Even Japanese matcha can have up to 6mg/L. Fluoride can increase manganese concentrations and decrease magnesium, etc. Musculoskeletal disorders and arthritic-like symptoms are very prevalent in countries where tea consumption is highest, like Ireland, and chronic fluoride exposure could be to blame.

@kiramiftari9486 3 месяца назад

… ironically, the very oils that they advise you to filter out are responsible for the health benefits of Coffee, lol 💁‍♀️

@myqp12345 3 месяца назад

CYP1A2 status would be interesting. WAG only people who respond to high caffeine intake with increased CYP1A2 production benefit.

@GA-lf2uh 3 месяца назад

But... How big is a cup of coffee (in oz or ml)? Instant, cafetiere/press, fillter or espresso/barista? Does it matter if it was caffeinated or decaffeinated?

@shielddelan5991 3 месяца назад

Does coffee cup made of one teaspoon of coffee is the same of one cup of coffee made from three teaspoons of coffee? Coffee cups doesn't seem to me like the right measurment unit.

@mikestopcontinues 3 месяца назад

How is a cup measured in these studies? A shot? A dose of caffeine? Does decaf count? Is there a comparable effect from matcha or green tea?

@conqueragingordietrying123 3 месяца назад

Hi @mikestopcontinues, 8 oz = 1 cup. Decaf was also associated with a reduced ACM in the 1st study. There is data linking tea consumption (not necessarily green) with slower biological aging: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-lq9YysNRjOQ.html

@mikestopcontinues 3 месяца назад

@@conqueragingordietrying123 thanks!

@peter5.056 3 месяца назад

This great and all, but coffee makes me feel absolutely dreadful.

@darrenparis8314 3 месяца назад

Do people who drink more coffee socialize more? Do they work more? Both of these things can be beneficial for slowing aging. These may need correction for too.

@KRRR820 3 месяца назад

I’ve noticed that even scientists are addicted to coffee and I’ve been unable to prove they aren’t putting out biased studies. Hopefully none of this data was produced by any industry participants too. A conflict of interest hunt would be worthwhile on this data.

@conqueragingordietrying123 3 месяца назад

10.1 million people in the 1st study (meta-analysis of 21 studies)... If the industry connection is true, it would suggest a global coffee conspiracy across many labs...

@Joey_Dasher 3 месяца назад

@@conqueragingordietrying123 or the meta-analysis is bad? and are these 10 million unique people?

@AmarSingh-uc7px 3 месяца назад

Can u do one on cacao or cocoa

@conqueragingordietrying123 3 месяца назад

Is there published data on cacao and biological age? Alternatively, ACM risk is here: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-QyU6Cw51sNY.html

@curiousbystander9193 3 месяца назад

who funds coffee research?

@theinvincibleone0136 3 месяца назад

Any research into types of coffee? Does caffeine concentration in coffee affect the results? For example Robusta coffee vs decaf coffee?

@conqueragingordietrying123 3 месяца назад

In the first study, both decaf and regular were associated with a reduced ACM risk. Beyond that, I haven't seen any other studies looking at coffee vs biological age.

@OneDougUnderPar 3 месяца назад

I can't imagine 5 cups a day,, let alone 20! That must be over 5L, I don't even do that with water unless I'm biking in the sun for hours. Would be interesting to compare this to water, juice, soda, etc. I don't see a serum sodium video on your channel , is that something you track?

@conqueragingordietrying123 3 месяца назад

Hi @OneDougUnderPar, although I collect serum sodium data for every blood test, I don't try to optimize it, at least not yet

@dbpook 3 месяца назад

Thanks Michael, question: what Ocha green tea is best from a health perspective out of the 11 they offer? Which one(s) do you drink?

@conqueragingordietrying123 3 месяца назад

Hi @dbpook, I can't say which is best for health, but I use Organic Sencha from Ocha & Co.

@StaffanOlsson-sw6tx 3 месяца назад

How would espresso do, compared with filtered coffee?

@pimacanyon6208 3 месяца назад

would be more like French Press, in that espresso is not filtered thru a paper filter

@BR-hi6yt 3 месяца назад

Well, blow me down - I drink 2 cups of coffee a day.

@bobbobson4030 3 месяца назад

Any randomised control trials on coffee/tea and biological age?

@conqueragingordietrying123 3 месяца назад

Hi @bobbobson4030, I mentioned at the end that limitation at the end of the video-if there are coffee-biological age RCTs, I'd be happy to cover that in a future video...

@katisugarbaker7349 3 месяца назад

Yeah, that data is fake.

@conqueragingordietrying123 3 месяца назад

10.1 million people in the meta-analysis Got some evidence that it's fake?

@TruthMattersMan 3 месяца назад

Caffeine reduces blood flow to the brain by 40%. So your adrenals kicked daily, while decreasing brain blood flow. Let's talk about who paid for these "$tudies"..... and ponder why they would do such a thing. To not realize that decreased blood flow will long term be atrophy, is laughable.

@BuellersBack 3 месяца назад

This study is brought to you by the coffee industry Lol. Next up, smoking, is it really that bad for you?

@conqueragingordietrying123 3 месяца назад

There are 2 studies in the video, which are you referring to? For the 2nd, "This study was supported by the National Natural Science Foundation for Young Scientists", not big coffee.

@kiramiftari9486 3 месяца назад

Smoking conventional cigarettes- def not… but using Nicotine for certain health hacks - absolutely! 👍