Kidney Function: The Missing Link In The TMAO-Health And Disease Story?

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Опубликовано:

18 ноя 2020

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Комментарии : 58

@richardpitkin1444 Год назад

I would investigate Taurine as it’s found in fish and supposed to be protective of Kidney. Maybe that’s the linkage.

@filobonda 3 года назад

Great video and explanations, thank you!

@ok373737 2 года назад

Fascinating video. Thank you!

@awestphal9602 2 года назад

Excellent presentation.

@cigall 3 года назад

So is there anything we can do to improve kidney function? Otherwise, it sounds like after age 40 we should be reducing animal foods...

@gastropodahimsa 2 года назад

Very helpful. Thanks

@aquamarine99911 2 года назад

Interesting to compare this with Dr. Michael Rose's theory that humans should eat more paleo as we age, for reasons he stated in your interview.

@neilchristensen538 3 года назад

This was a really interesting video. I eat 49g salmon/day (12oz spread equally over 7 days). I used to eat 98g/day, but got worried about the mercury. When I started eating daily salmon like this, I noticed that my blood pressure dropped about 10 points and stayed at the lower level as long as I ate the salmon. (I have been taking my blood pressure weekly for a long time.)

@Truthseeker11011 3 года назад

Maybe plasma TMAO is just a marker for kidney function, and so higher TMAO is associated with higher all-cause mortality only because reduced kidney function is associated with higher all-cause mortality.

@andrewtaylor9799 2 года назад

Nice analysis to get to the bottom of the issue. So people with weak kidneys shouldn't eat too much meat.

@nemanjababic7141 Год назад

When you calculate eGFR, do you adjust it for body surface area? Or you use the CKD-EPI which does not do any adjustments?

@peterz53 3 года назад

Thanks. @ 6 m the table shows high p-values (nearly 1) for high eGFR. I thought 0.05 or less was the desired threshold. So, should we rely on the high eGFR data ?

@jasonbrice9921 3 года назад

The idea is to counteract the negative effects with something positive.

@padmeshsethuraman5617 Год назад

In our part of India many become vegetarians as they age.

@davidbengel5247 3 года назад

Astragalus is protective of kidney function/sepsis, etc..

@KJ-um1gq 2 года назад

What’s your take on extended water fasting, Doc?

@jskweres2 3 года назад

Is there a way to increase eGFR?

@jbosson82 Год назад

It should be noted that meat chicken and eggs do raise TMAO among non-vegans. It comes down to the different microbiome. Fish once or twice a week would appear to be optimal. Or full vegan and flaxseed+ curcuma for DHA liver synthesis

@mike0133 3 года назад

The cause aren't proteins but an imbalanced gut (like dysbiosis) were some bacterias like Proteus, Edwardsiella and Provodencia, convert choline in TMAO.

@jp7357 Год назад

Love this video .. but … eGFR is a let peeve of mine as the calculation includes age. Therefore I don’t agree with mapping eGFR against “age” .. that’s mapping age against age. If creatinnne stays constant and age changes .. I really disagree that eGFR should change .. I’m interested in measuring my GFR not some epi derived estimate.