Lutetium-177 (Pluvicto) vs. PSMA-Actinium |  

Actinium 225 has been available over seas for 5 or 10 years. I got it in Germany in 2021. The US is once again recreating the wheel and taking credit while delaying care.

please mention the sides effects of actinium which are more serious than lutetium.

❤ bendiciones 🙏 los que sufrimos está enfermedad y sin opción médicas rogamos a Dios por el alivio de nuestro sufrimiento

Thank you so much for making this video happen Alex. I requested info on Actinium-225 under the comments section not that long ago🙏. Actinium-225 is becoming available here in South Africa as an approved treatment option in early 2024. I have advanced metastatic PC ( Gleason 10) but am still responding to hormone therapy. I am just gathering as much info as possible for if and when i become castration resistant. Thank you for helping with that. You and Doc Scholz are just super 🌟 stars!

If response rate is high in hardest cases, what is the downside for less advanced cases which will likely have a higher probability of success?

Why are these advanced meds only used on really advanced stages instead of going thru all the ADP and Chemo. It seems like this is the way to go instead of what I call weed control. Take the med PSA goes down later the weeds grow back and PSA go up and the Merry Go Round continues.

I am 4 years into standard hormone treatment. 2 years on eligard and chemo. Psa went .017. Started climbing so added radiation and xtandi. After 2 years, psa climbing slowly now 2.67 and some changes in mri noted plus new growth at T10 and small spot on skull. It is November 2023 , I was wondering date of this video. Dr George at Roswell has agreed with changing up my treatment to radiation but did not specify which. It seems my cancer is very aggressive. Should I push for the newer type? I'm being treated ate Roswell Park Cancer Center in Buffalo NY. I'm scheduled for my first PSMA-PET SCAN Dec4.

Great info thanks

Well explained and very informative. Would like to know alternative diagnosis for biopsy since for those who cannot tolerate enima and for those whose platelets are on lower side say 100k

I'm confused on the psa numbers my husband is 82yrs old has a psa of 25 gleason score 4+5 =9 with no signs of spreading. Drs want to do brachytherapy hdr, hormone therapy and radiation. Can someone please help me would Lutetium something do able are all of these treatments necessary. We still want a measure of quality of life.

I had 4 infusions with Lu-177 (they said I would get 6, but only did 4) & my PSA went from 5 to .3. They also said my scans showed no disease progression, but that was a misdiagnosis as I developed more bone metastasis & within 6 months, my PSA rose to 15.7. I then started chemo with taxotere & got my next PSA results after 2 rounds & it was 31.8!(whether or not this was a PSA spike, IDK) Had my 3rd round of chemo a week & a half ago(even though it appears to not be working because I now have even more bone metastasis & the radiologist said this is still very treatable - question is: with what? As low dose chemo has made me feel like garbage for a week or more after each round, so I can only imagine how I’d feel after stronger chemo(plus a lost more hair that the some my dr said I would lose)). Fortunately, for now, my metastasis is staying in the bone(pelvis, T7, & now ribs), but it has been quite depressing that all the treatments & misdiagnosis & after the excitement of having my PSA get so close to undetectable, it is rising very quickly now. My oncologist mentioned nothing that this latest spike could very well be from the chemo, I had to google it myself & found 2 studies at the top of the search that indicated this can happen. One study had the last line that said for oncologists to tell your patients this could happen to alleviate fear & anxiety. I was scheduled for a 4th round of chemo early in December, but I don’t know what the status of that is and am fearful if low dose chemo makes me feel like a wreck, what exactly are my options going forward in the short term? With this new treatment not yet approved, I guess it is not an option. Just tired of all the failures on my journey thus far with only one treatment out of the 7 showing promise but ultimately failing, too.

Are there any studies of potential benefits to moving PSMA-Actinium EARLIER in the treatment path, such as combining it with triplet therapy in search of a CURE?

My Dad’s PSA was nearly 1300, uncovered during emergency urine retention, and sudden extreme neck and leg pain. Imaging revealed bone mets, and unfortunately vertebrae damage. He went on Lupron immediately, then daily Abiraterone and Prednisone, and Gosarelin every 3 months. Now 1.5 years out, PSA is

Since Lu-177 only usually decreases PSA half percent, what do doctors usually supplement after. Example: PSA at 100 when Lu177 started. After Lu177 PSA goes down to 50. At 50 PSA I would think there are still huge concerns and met bone pain. So what would be the supplement treatment to help with that? Would then spot radiation to certain mets after Lu177 help? Or does spot radiation not very effective after the body has received Lu177. I’m not mentioning the new treatment discussed due to it being so new. I’m trying to understand plan for someone that received lu177 when they hsd high psa, and lu177 helped to decrease psa but psa is still not in good range.

Is this available in india? Which hospital?

Once I get injected with Pluvicto will the radiation affect my dog?

In the next few years I anticipate nuclear facilities around the world stepping into the Actinium space. It seems to be a phenomenal new approach.

when will it be approved!

Actinium reduced my PSA 99 perçemt. I had some year long side effects

I never realised that mark and Alex were wed

Outstanding explanation of the promising new treatment!

Thanks for sharing

Trust no doctor who pushes more and more drugs into you I made this mistake . I started out with a PSA of 49 I am now taking nothing I feel great at last entering year five ... who is counting I bought a vintage BSA motorcycle and a Vintage sports car life is for Living as large as you can.

When can we expect to see actinium replacing lutetium in clinical trials as a first-hand solution?

Great info! Do you have a video on side effect’s usually seen while and after the first dose of chemo? And usually when those side effects are seen or take to develop? Are there things you can do to prevent or decrease these side effects? Mainly low wbc count, fatigue, taste changes, nail or mouth issues. The WBC is the biggest concern. My dad is in his 80s. Is there a difference in very low and regular dose chemo when it cones to side effects. I’m a caregiver and my dad is getting chemo for first time. I wanted to know what to expect during and after 1st treatment and how what I can do to help.

Husband takin Ivormetcin for recurrant prostate cancer is it safe please and will it help

This is exciting news. Thank you for sharing. Happy Thanksgiving!

My psa is 0.2 can I stop hormones after 4 months. Before treatment my psa was 13.7 at its highest level. Had radiation and it went down to 3.8 then it went up to 7.5 more radiation it had spread to my pelvic lymph nod now I am on hormones for 4 months and my psa is 0.20 I am not happy with the side effects and was wondering if there is a point I can stop hormones is it 0.0 only

My dr won't recommend plavicto or lutieum177 psma over chemo. She claims once these drugs are used I'm locked out of chemo ! And I've had doctaxial chemo with limited success (4 months)

Thank You!

Is Actinium available in Australia 🤔❓🙏

I am 67 years. Old

Thank you for your information. Your videos are excellent.