MS Virtual 2020: Remyelination Clinical Trial Results - Bexarotene - Dr Will Brown 

Thanks for the comment demoskunk and I'm sure that view is expressed by many in the MS community. We will continue to provide updates on clinical trials that are recruiting people living with MS, so stay tuned to all of our channels. Participating in research is such an amazing thing to do, not just for the potential benefits that the individual may derive, but also for the help that it provides scientists and the rest of the MS community. Thank you for expressing such a willingness to be involved - Brett

@@MStranslate1 Thanks for the support, Brett!

Seems Drs. and researchers don't understand that. I'd rather have 10 better years ahead, than 30 with progressing disability.

same.

Indeed Richard! We can't thank Will enough for giving up his time to chat with us and share these important findings. We're sure that we will feature Will again at some point in the future. Thanks, Brett

@@MStranslate1 credit goes to yourself also for making these videos. Thank you.

Definitely Mathew. It's always important that results are viewed in the right context. This trial was neither a massive success, nor a massive failure...yet often we think it has to be one or the other. As you say, the important thing is that we are a step closer. As always, thanks for your engagement on our content, it is much appreciated - Brett

what´s EBV?

Same symptoms here. I began the Wahl's Protocol back in Feb, 2023 when admitted for a week. Was given IV anti-inflammatory IV for at least the loss of vision, then released. When I came home, I immediately began Wahl's Protocol. Within weeks, vision slowly returned to normal. Balance improved, and I began to feel noticeably better, until I went back to my old processed foods regular diet, and the signs and symptoms are slowly coming back now.. So, it's back to Wahl's to manage the auto-immune problem, but I am convinced, that Wahl's Protocol helps substantially to slowly restore function. Best, MDM. \\//

It's Metformin.

Thanks for the comment Quantum. I think at the moment we are in a position where we want to be exploring as many different avenues as possible, especially when it comes to myelin repair. As we have seen with the existing therapies for MS, they don't all work for every individual. Therefore, I think it's reasonable to suggest that we may see something similar in this space as well. By developing different strategies, using different targets, techniques and approaches, I'd hope that we would then have multiple options that, between them, would help all people living with MS (both relapsing and progressive). It's an emerging space and we will continue to provide updates on all of those different approaches. Thanks again - Brett

Hi Iqra, thanks for your question. Yes, we do have a lot of evidence now that suggests it is possible for the myelin sheath to be repaired. In fact, demyelination (damage to the myelin) isn't that uncommon, it's just usually it is repaired quite quickly. This is not the case in multiple sclerosis and so researchers are trying to find a way to promote that repair process. This trial, although it failed, did show that the myelin repair was possible and now will be continuing to try and find the right compound that generates the benefits without the bad side-effects. Thanks, Brett

@@MStranslate1 what's your feelings on this newest discovery? multiplesclerosisnewstoday.com/news-posts/2020/10/29/discovery-of-new-cell-may-be-key-to-treating-incurable-neurological-diseases/

@@Durace11Bunny I feel numbness unblance walk problem

@@iqraiqq7314 are you diagnosed with MS? These are all unpleasant symptoms, but work with you health care team to lessen the impact of these.

@@Durace11Bunny yeah diagnosed MS I use the ocrevus

Thanks for the comment Vivianne and I think the flooded basement analogy works well. While I know it can be frustrating, please know that there are many, many dedicated researchers (such as Will) that are working incredibly hard to find answers to help improve the quality of life for people living with MS. We will continue to try and help accelerate this process as much as we can and help however we can. Best wishes, Brett