Scientists at @IRBBarcelona identify a promising drug, RBS-10, capable of selectively killing cells that are resistant to protein degraders, thus providing hope in overcoming such resistance.
Uncovering the pivotal role of the enzyme NQO1, this study sheds light on a key vulnerability in resistant cells and offers potential insights that could be useful for future cancer treatments.
Read more about this work, published on Angewandte Chemie, here ➡️ shorturl.at/tzDOS
#chembio #ChemicalBiology #DrugSDiscovery #ProteinDegraders #TargetedProteinDegradation #TPD #research
7 сен 2024
