All my go karts have been only one wheel drive. This is the go kart from my how to make a go kart frame video. This one has a 5/8 inch dia. bolts welded on each end to mount the wheels.
Not sure how much work you plan on doing to that thing, but if you have a welder, you should thicken up the welds at the point where the outside rim connects to the inner cylinder/hub part, otherwise they'll end up snapping. Those tires are made of super soft rubber and don't last on the road, but in cold temperatures they might hold up for a bit. The best wheel/tire setup I've found other than spending like $400+ on go kart wheels are the 15x6" Turf Saver riding lawnmower wheels from HF. They're around $70 each. @@TemperDriven
