Ozempic is a game-changer. Here’s how it works.

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This diabetes drug could be the future of weight management.
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Ozempic, a medication developed to manage type 2 diabetes, has been in the news a lot lately because of one of its signature side effects: drastic weight loss. Both Ozempic and Wegovy, Ozempic’s counterpart approved specifically for weight loss by the FDA, are brand names of a drug called semaglutide. Semaglutide is one of several drugs that mimics a crucial digestive hormone called glucagon-like peptide 1, or GLP-1. It amplifies a process our bodies perform naturally.
GLP-1 is released in our intestines when we eat, and there are receptors for the hormone in cells all over the body. In the pancreas, GLP-1 promotes the production of insulin and suppresses the production of glucagon. This helps insulin-resistant bodies, like those with type 2 diabetes or obesity, manage blood sugar levels. In the stomach, GLP-1 slows gastric emptying, extending the feeling of being full. In the brain, GLP-1 suppresses appetite, which also promotes satiety and curbs hunger, so we eat less.
In late 2022, a rush to use Ozempic off-label for weight loss, likely prompted by its sudden rise in popularity in social media, led to a shortage of the drug for people who need it. But more drugs like semaglutide are currently in the process of being approved by the FDA to be prescribed for weight loss, likely signaling an end to the shortage and a promising new generation of medical treatment of obesity.
Further reading:
Mila Clarke's RU-vid channel: / thehangrywoman
The New Obesity Breakthrough Drugs, by Eric Topol
erictopol.substack.com/p/the-...
The Discovery and Development of Liraglutide and Semaglutide, by Lotte Bjerre Knudsen and Jesper Lau
www.frontiersin.org/articles/...
The pregnancy risks of Ozempic and Wegovy need more attention, Julia Belluz writes for Vox. Read more here: bit.ly/41znHCv
Note: The headline on this piece has been updated.
Previous headline: The game-changing weight loss drug, explained
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Опубликовано:

13 мар 2023

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Комментарии : 1,9 тыс.

@Vox Год назад

There's a lot about Ozempic we didn't have time to get into in this video, including more about medical discrimination around obesity and more context around recent drug shortages. This article from our website, written by Julia Belluz, provides more info: www.vox.com/science-and-health/23584679/ozempic-wegovy-semaglutide-weight-loss-obesity

@aprilmason1616 Год назад

Will you do an in depth video as well? It is so important for the public to have all the correct information. If I could I would love to help, but I study still and live else where. Im just so passionate about food and health related topics and got super excited for the video haha Okay bye 👋

@NadirAgha Год назад

*including more about it's side effects, long term effects, indications, contra-indications, and how necessary it is to use it only if a doctor prescribes it.

@mysisterisafoodie Год назад

Honestly this is a topic where there is just a lot of unnecessary outrage. There isn’t enough supply for the current demand. They should just make more. Done. Whoever wants to buy it, if they can afford it, should be able to. If not, lobby your insurance companies to do better. Better yet, why don’t you elect officials who will give y’all public healthcare? And whoever needs to prescribed it should be able to. I don’t hear anyone complaining about milk, because growing children need to drink it. There’s enough for recreational milk drinking and for children to drink it too.

@gwenstacyspidercat4294 Год назад

You "didn't have time to get into?" My siblings in christ, you decided the parameters of the video. The medical discrimination and context around drug shortages should not be considered secondary content, bc most ppl watching this are never going to read your article...

@CristinaNoujaim Год назад

Why doesn't this video (or your article) cover the studies that show that weight is gained back and more statistically by those who *stop* taking ozempic? Or the long term effects on the body?

@Vonononie Год назад

“Maybe you’ve heard the jingle” no, because medication isn’t advertised in my country!

@petar4onachev Год назад

Bless your country! I am tired of seeing medical adds everyday, where are you from?

@StellaMariaGiulia Год назад

Same

@jessealexander9074 Год назад

Its only legal in the U.S to advertise medications

@shana736 Год назад

@@jessealexander9074 Direct to consumer advertising for medical and pharmaceutical drugs is only legal in two countries which are the US and New Zealand

@Vonononie Год назад

@@petar4onachev UK but I don’t think prescription medication is allowed to be advertised anywhere in Europe. Over the counter stuff, like basic painkillers and cold remedies, are allowed to be advertised but they aren’t heavily pushed. I can’t see a reason why medicine should be advertised, isn’t it given based on medical need not because you want it?

@angelina-po7hq Год назад

As someone who works in a pharmacy, I have seen how this hurts many patients who need this medication to control their diabetes. For almost 3 months straight we could barely receive this drug to dispense due to the unexpected increase in demand. I completely understand the want to lose weight and ozempic does help with this, but people with diabetes need medications like these to live their lives.

@steventhan93 Год назад

Are you saying T2D relies on this med to stay alive? Because that's not true at all, this med is FDA-approved in 2017, and T2D predates that by a long shot

@tdawg719 Год назад

Ditto

@Bassen97 Год назад

@@davidbjordan people w diabetes need it. People who are obese can stop eating junk food and start eating healthy and less and exercise. Not that hard

@stevethepocket Год назад

@@davidbjordan So really the solution is to just ban processed food.

@jaguarrior Год назад

@@stevethepocket banning processed food, would not do anything to make my diabetes better. Mine is caused by PCOS, a metabolic disease

@ericshaker9377 Год назад

You guys should really bring on a credentialed source like a doctor or pharmacist for videos like this

@tumblingrosesstudio Год назад

Good idea

@firstprinciplesinvestor3464 Год назад

right, like they used some random lady off youtube as their primary source

@dominicrincker8280 Год назад

It felt like an ad

@allisonjoydahlen569 Год назад

I agree!

@phinsup402 Год назад

More like a passive aggressive sales pitch, shame on you Vox.... bring in a medical expert (scientist) next time.

@TammyJerkChicken Год назад

I’ve been trying to lose weight after my dad ended up in the hospital due to diabetes, I had been hearing that ozempic from this is a quick fix to life long commitment but in the end the hype is causing a shortage for the people like my dad, who’s still here only thanks to his able to have access to these meds. I really hope that the supply issues improve but also doesn’t become out of reach due to expense too.

@toasted_.coconut Год назад

Their lives matter, too.

@hjewkes Год назад

The good news is that production has ramped up massively over the past 6 months, so I would expect the shortages to get a lot better soon (NovoNordisk is on record as saying late march)

@laurenconrad1799 Год назад

I feel you so much. I’m in the exact same scenario. Ozempic is a lifelong commitment and not a quick fix. The side effects are no joke. But it truly can help people whose genetics make it harder to lose weight than a person born with a faster metabolism. ❤️

@I_WANT_MY_SLAW Год назад

They can make tons. They an unlimited supply. Its just the healthcare system is very corrupt.

@zjsz4954 Год назад

A drug is a drug how you use it is irrelevant. The problem is the labels we attach to drugs being a “weight loss drug” or a “diabetes drug”

@TheHangryWoman Год назад

Mila here! Thanks to everyone for your supportive comments and Vox for letting me share my experience. When I started Ozempic for diabetes management, few people talked about the effects, so I decided to document my progress. I'm so grateful that it has made diabetes management easier for me but disheartened that vanity weight loss has made it out of reach for patients who need it. Jimmy Kimmel even made a joke about it at the Oscars - that's what I meant by vanity weight loss and trivializing the medication. I hope this is a good solution for people living with diabetes and obesity, but even more so, that the long-term effects don't cause additional health challenges. That remains to be seen, and I'll be documenting it for as long as I need it (or can afford it or access it).

@katiemoreno3013 Год назад

@@crazyprophet3276?? She literally has T1 diabetes??

@FutureCommentary1 Год назад

Thanks for putting yourself out there so that people can have concrete examples. I struggle with weight myself. Very hard. Glad you are getting help both for diabetes and for weight management.

@KunalM-ec3pm Год назад

Wish you great health 🤗

@drizztcat1 Год назад

I'm glad you told your story! As a fellow diabetic who has had success with Semaglutide, it's good to see the message getting out about the drug, even if it means occasional limited availability. I'm now on Mounjaro, and I've had even better luck with it, with fewer side effects.

@Vox Год назад

It was so great talking with you Mila, thank you for sharing your experience and perspective on this story with us! -Coleman

@rosethompson1983 Год назад

I used to be 280 pounds, going blind due to a rare obesity complication called Intercranial Hypertension, but was able to take Ozempic for just 4 months and for the first time in my life felt full. I’ve kept up the initial weight loss and so far lost 80 pounds. Without this medication, I believe without a doubt I would be blind in my left eye by now.

@MsSarcasticity Год назад

The reason why you cannot feel full is most likely due to eating carbohydrates which cause hunger hormones to increase. Completely remove carbohydrate sources and increase saturated fats from animal sources like butter or beef tallow. You'll feel a lot fuller on less food without without shooting yourself up.

@kidsdomath1330 Год назад

@@user-kr6jg6qb7l Ad.

@andreasamardzija1496 Год назад

I am not obese but I do have issues with binge eating and never feeling full, so I can't imagine how amazing it must have felt to be satieted. I'm so glad you've reached a healthier weight and saved you eye and possibly life.

@cat-.- Год назад

Intercranial hypertension? so you have hypertension between your two skulls?

@ItsDanny91 Год назад

I also have this condition. Im 200 pounds so im at the point where its causing headaches and ear ringing. My optic nerves used to be swollen which i was told leads to the blindness

@averycoolgal Год назад

I've heard A LOT that challenges Ozempic as "safe". I'm a little wary of how we grazed over Mila's heart palpitations... I understand many drugs have side effects and for those living with diabetes, Ozempic really is a game changer BUT as we see it presented more and more as a weight management tool, I just worry about how positively it's framed in this video. I'm not gonna lie, this feels like an Ozempic promotion to me :(

@basmalawessam2488 Год назад

Yes! I expected them to go a little over the heart palpitations part, which sounds super dangerous to me. I think people need to wait until Ozempic is properly examined to be deemed safe for people using it for weight loss specifically.

@theuscivicsnerd7070 Год назад

The severity of heart palpitations and the frequency of them we'd need to look at. Heart palpitations from this doesn't surprise me but it's not a horrible side effect.

@Dan-uh9sg Год назад

Heart palpitations are a common side effect of many medications. They also tend to be caused by medications that cause dehydration. GLP-1 agonists typically have a diuretic effect AND reduce thirst (as a side effect of increasing the feeling of fullness). Properly hydrating and getting electrolytes is a good first step to try in that case. With these medications, it's important to be proactive about hydration and frequently sip liquids. She likely had a conversation about it with her healthcare provider and decided on steps to ensure that it does not become an issue before she started using Ozempic again.

@jonathanodude6660 Год назад

keep in mind you take it once weekly. if its constant palpitations id be more worried. many people get worse symptoms from coffee.

@MsCorpora Год назад

I agree! Calling it a game changer in the title is way too encouraging!

@ayarel01 Год назад

Vox, I’m disappointed that the abuse of this drug by Hollywood and influencers for a “quick-fix” to weight loss wasn’t emphasized as much as it should be. I have a family member that is dependent on it to stay healthy, yet shortages are making it difficult for them to obtain and afford it. And what about the long-term side effects for those just wanting to drop weight quickly? This video should have been a lot more cautionary.

@monkeylordofdoom14 Год назад

I was thinking the exact same thing!!

@justduro1527 Год назад

I dont think the drug has been around for long enough to see long term side effects

@thundercaaat Год назад

100% AGREE!

@narnigrin Год назад

@@justduro1527 The long-term/longer-term effects that have already been observed, afaik, are basically that if you use this drug to lose weight and then go off it when you've reached your target weight, you tend to very quickly gain all of the weight back. Which means that if this is a magic "get thin quick" drug, it's a get thin quick drug you'll have to keep taking for the rest of your life.

@laurenconrad1799 Год назад

I think this was the best explanatory video about what’s going on inside the body that I’ve ever seen. They could always do a part 2 to address the Hollywood issue. It’s tough to tackle everything in 7 minutes.

@Jerguu Год назад

I want to point out that this drug has been a game changer for several people I know in terms of weight loss. It's not just a few pounds - we're talking about 40-50 pounds on someone who used to be 200-210 pounds. It's a life changing amount that suddenly takes a lot of load off your body.

@nicholsonfile Год назад

Stimulants work that way as well.

@windwhisprz Год назад

Exactly and when people lose weight they feel better about themselves and then they are motivated to take care of themselves better and eat healthy because they finally see results. Losing 10 pounds can kick start someone into making other lifestyle changes for the better.

@C1azed Год назад

@@windwhisprzstatistical 95% of peopl gain the weight back within a year of stoping the meds, drugs can't change bad habits

@peter.gorski Год назад

And they rebound when they stop using it.

@Jerguu Год назад

Maybe - maybe not. We don’t understand enough about obesity to know. It’s between the patient and their doctor. The more likely situation is they taper back down to a maintenance dose.

@8antipode9 Год назад

I have type 2 diabetes but I am far from obese, and my doctor put me on Ozempic for a while. It did a good job with what it's supposed to do, but I HAD to stop. I was felt nauseated CONSTANTLY and I finally decided that life on Ozempic wasn't worth it. Those side effects are just too much.

@kauntroap6339 Год назад

try intermittent fasting

@SomeDudeQC Год назад

@@kauntroap6339is that good for diabetes?

@bria1660 Год назад

I stopped because my kidney functions were impacted ... also the side effects for me were horrible.

@inuhundchien6041 Год назад

The nausea make you not eat thus get skinnier

@starlett08 Год назад

Injecting it in your thigh instead of abdomen helps or eliminates the nausea.

@somerandomfella Год назад

In Australia diabetics are missing out on this medication due to the weight loss crowd creating shortages.

@zXPeterz14 Год назад

Imagine being so lazy that you would rather take a diabetic’s medication instead of eat less and move more

@stuartclifton4764 Год назад

@@zXPeterz14 this could be something useful to me, as I have an extreme sweating/overheating condition where even low levels of physical exercise can lead me to pass out :( struggled with it since I was around 13 and I'm now 26, not insanely overweight but this could help me massively!

@noname-zp1yh Год назад

@@zXPeterz14 if it was that easy they would have already done it.

@PhilfreezeCH Год назад

@@zXPeterz14 did you watch the video? You still need to do that, semaglutide just makes it easier through things like supressing appetite and so on. It helps you to eat less.

@Kamikazeesouled Год назад

@@stuartclifton4764 then just eat less.

@OrianaZ5 Год назад

I was diagnosed type 2 on October '22 with an aic of 7.2 and I weighed 240 lbs. I was started on Mounjaro and lost twenty pounds over two months. Due to insurance not covering anymore I was switched over to ozempic and although the weight loss is slower my recent aic as of March 10 is now 5.6! I needed help with controlling my hunger and cravings and this definitely helped with that. Yes you still have to eat right and exercise to really see the benefits. As of today I'm 203 lbs (slow but steady). Ozempic and other drugs like it have made a huge difference.

@shaanchaudhry5719 2 месяца назад

If you don’t mind me asking what is your age and height? Did ozempic put your diabetes in remission or is it still something that is always there?

@OrianaZ5 2 месяца назад

@@shaanchaudhry5719 Hey so for reference I was 38 years old when I started and 5'5". Now im 39 with my last aic of 5.3 and weigh 155lb. Doctor said diabetes is in remission. Hope that helps and good kuck!

@sarahm4669 Год назад

In Canada they're not allowed to advertise the specific use of medications or use jingles, so we get a lot of extremely vague "[drug name]: ask your doctor" commercials and I never knew what Ozempic was used for

@salmay4266 Год назад

This sounds too good to be true, and when you take into consideration the long history of pharmaceutical companies' predation on the most vulnerable, the whole thing makes me very skeptical.

@patriciacsapo Год назад

This video sounds like an ad

@rcs3681 Год назад

It definitely is considering all the side effects it comes with. Nausea, digestive issues.

@CarSVernon Год назад

yyyyep

@yaeli_i_guess Год назад

you're right. i worked in a pharmacy and the pharmacist told me exactly this- nothing good is ever without a 'catch'

@sarachaya Год назад

Yeah they forgot to mention that ozempic created thyroid tumours on rodents

@royw-g3120 Год назад

In case people are wondering why the natural GLP-1 molecule has been changed, it is because in the body it has a very short half-life, to be used as a medication it would need to be in a permanently attached pump device, impractical and expensive. Hence longer acting forms were developed that resist DPP-IV the enzyme that breaks it down.

@gilessteve 11 месяцев назад

I was. Thank you.

@officiallyawesome8585 Год назад

At least their commercial is catchy 😂

@Johnsonsvideos Год назад

I hate that people have to watch commercials. I would pay anything to never see another ad in my life

@Utsav_Viradiya Год назад

@@Johnsonsvideos "anything"? - Then pay one million dollars now!

@BigDaddyWeightLossJourneys 11 месяцев назад

I lost 75 pounds on ozempic in 12 weeks!! I love it and I am a big guy with a type 2 diabetic this has been a life-saving game changer!!!!!

@joeytheestallion 3 месяца назад

I know you commented this 7 months ago, but how are you doing now? How much did you lose, and how quick? I'm in the process of getting Ozempic for weight loss myself

@Fleetstreetbestone 3 месяца назад

@@joeytheestalliondo not get this evil drug

@michellecrawbuck1198 2 месяца назад

Did you have any side affects

@moya_moyz5471 Месяц назад

@@joeytheestallion I wanna know too. I’m abt to start this after my sleeve got reverse

@peachy4510 Месяц назад

What strength did you take ??

@felipeallegro9683 Год назад

I struggled with my weight most of my adult life and finally had an solution with the Gastric Bypass. It’s important to understand obesity has a physical and mental aspect, so being in therapy for almost 4 years as well. So many people change one addiction to another or worse don’t follow all medical protocols and end up sometimes in a worse shape.

@livelongandprospermary8796 Год назад

I havent gained anything back since stopping wegovy (same med as ozempic, different dose). I went from 212-185. That was late 2021-early 2022. I have fluctuated a little, losing some and gaining a little back but ive been holding close to that 185 or so. I havent made any changes either, since i weighed my heaviest. Like im eating the same i did at 212 and its been almost a year off the meds. Weird that back then i was just climbing and climbing on the scale with the same exact diet that is allowing me to maintain a much lower weight. Idk 🤷‍♀️

@FlabbyTabby Год назад

IMO gastric bypass is a bad idea. Main reason people have trouble losing weight is because almost all of them don't know the real science behind it (hint: insulin is the key). Or because of medical conditions. It should be a last option. Surgery in general is risky.

@FatNebraskaMom Год назад

Straight up true. 100%

@azca. Год назад

Did you first trying eating in a calorie deficit or attempt to exercise at least 30 minutes a day? No one ever talks about working out and goes straight to weight loss meds

@laurenconrad1799 Год назад

@@FlabbyTabby Sounds like the opinion of someone who isn’t a doctor.

@JacobCarlson Год назад

Thank you for choosing to focus on how this drug is SOO lifechanging for those living with diabetes and obesity. That's really important and not enough are spreading that message.

@gilbertodemelo Год назад

Here in Brazil quite often you meet upper class women who make use of Ozempic. Many doctors will prescribe it just for aesthetics, not for health reasons.

@rafinha7081 Год назад

E eu achando que esse remédio não existia aqui.

@JL_Lux Год назад

Weight loss is health reasons 😊

@gilbertodemelo Год назад

@JL-xf2zh upper class people in Brazil are already a lot thinner than average

@JR-90 11 месяцев назад

@@gilbertodemeloIs it easier to get your hands in this medication in Brazil?

@vir_rm 3 месяца назад

@@JL_Lux It strongly depends. For obese people, probably. For people with no complications, it's an unnecessarily risky choice.

@jessicasadler3460 Год назад

Semaglutide has been a game changer for me, currently I am down 71 pounds and almost to my goal with 34 pounds to go! I have tried for years to loose weight but struggled. With being able to loose weight I have more energy to exercise.

@JazzParrott 2 месяца назад

Ik you commented this awhile ago, but how fast did you see results with the semaglutide?

@bria1660 Год назад

I was prescribed Ozempic for diabetes 2. I loved it because I no longer had to take 3 pills a day. The side effects for me were horrible ..stomach pains, gas, diarrhea, constant burping, heartburn ..but I did lose 15 pounds in 2 months. My Doctor took me off medication because it also had negative impact on my kidney functions. The downside was as soon as I stopped using the medication, my food cravings came back and I gained all the weight back within 4 weeks.

@allisonscanlan4144 Год назад

Most people who move to europe lose weight and it stays off

@JR-90 11 месяцев назад

Maybe if you changed your eating habits, this wouldn’t have happened. It doesn’t matter if you take something like this and lose weight, if you’re gonna keep eating junk food afterwards.

@bria1660 11 месяцев назад

@@JR-90 No, I try to eat healthy and only eat junk food occasionally. Whenever I would try to eat, I would frequently get nauseous. Foods I love did not taste or even smell the same. I found myself taking a few bites and then throwing away my food. Also, I found that I could not eat anything late at night. I could not drink alcohol or soft drinks or I would pay for it for about 4 hours with constant burping and gas. For me, Ozempic was not a pleasant experience and I do not miss it.

@supergg07 4 месяца назад

I have been taking Ozempic for a while I’m over the side effects and I have lost 50 pounds. I am at a standstill though with the weight loss but that’s OK for now. I have chronic kidney disease and it has never did anything to hurt my kidneys in fact with that, and my pill I take, my kidney functions have been going up

@bria1660 3 месяца назад

@@supergg07 Good to hear you are having positive experience. Continued good luck. I will say when I stopped taking Ozempic, my appetite came back with a vengeance along with the weight gain. Just curious but did your doctor say you will need to continue taking this medication to retain the weight loss?

@sarwat.qamar96 Год назад

My mom uses Ozempic weekly for type 2 diabetes that she's had for almost 30 years now and we live in Pakistan, so it's great to hear this drug is FDA-approved, and to be able to just learn more about my mom's symptoms and how the drug works.....Thanks Vox!

@stejannaone4141 Год назад

FDA has lost its credibility with the Opioid menace - both with Oxycontin and Fentanyl.

@JR-90 11 месяцев назад

Question: how do you get this without prescription?

@ranaka007 4 месяца назад

@@JR-90 in a lot of South Asian countries, we can get most of the medicine off the counter, without a prescription ✌️😬

@SilkCrown Год назад

Weight loss is not a trivial or superficial desire, it is a medical need that can drastically improve people's lives and save lives. We should not be pitting T2D against obesity, we should be asking for additional production of this drug.

@Tonixxy Год назад

Only smart comment here

@celery7810 11 месяцев назад

Eat healthy, dont resort to drugs to lose weight.

@DivineSina 11 месяцев назад

@@celery7810 eating healthy has so many layers to it, what is deemed as healthy could possibly not be America has to unlearn and relearn so much

@celery7810 10 месяцев назад

True, but drugs are not the answer unless you actually have a disease

@Tonixxy 10 месяцев назад

@@celery7810 obesity is a disease

@Maxtee77 Год назад

Video did a good job explaining the MOA. Just note that this requires a prescription from a doctor because of some contraindications associated with use. Not a panacea for good health, it will reduce your weight but you also have to improve lifestyle.

@HachBoxe Год назад

That's amazing to see innovations from side-effects.

@aprilmason1616 Год назад

It is! It think thats why we can use one drug for a variety of diseases

@laurenconrad1799 Год назад

I agree. ❤

@icomment4692 Год назад

Listerine

@SomeDudeQC Год назад

@@icomment4692glycerine

@anniej1580 9 месяцев назад

Thanks for the informative & positive video! I wish you the best! 🌻

@lekiscool Год назад

As a type 1 diabetic I’ve been vocal about leaving diabetic medications for those with type 2 and obesity. These are important medications to help them get back on track not because they have 10lbs to loose.

@Pastacrest Год назад

While it definitely should be prioritized for those with diabetes, if production can lead to enough supply for both diabetics and the overweight, why not give to both? If anything, the reduction in overweight people takes demand off of diabetic treatments for those risking type II

@thesupergreenjudy Год назад

I am sure they will bump up production - The issue is that many view the idea of treating obesity with medication as a vanity project when it's just as much of a disease as Diabetes Type 2 is. You could reverse Type 2 Diabetes naturally as well - so to say that people should just lose weight with willpower doesn't work. And weight loss will also bring down the amount of Diabetes Type 2 cases. Edit: I just realised that you don't object to using Ozempic for Obesity although some have objected that. Many who use it are probably obese. I think there are few people who are skinny who will want to use it and from what I understand, private companies check their clients weight first, at least in the UK

@Call-me-Al Год назад

Only rich people with 10lb to lose get ahold of this during shortage, people who get ahold of this now are more likely to fall into the 100lb or even closer to the 1000lb category. Especially because invasive surgery (lapband, etc) is way riskier than taking this. I do find it outrageous that there isn't a priority queue for medications when there are shortages though, millionaires and billionaires who want to lose 10lb shouldn't be able to get it more reliably than actual diabetics. Healthcare cannot be a for profit industry.

@AnymMusic Год назад

@@Pastacrest because let's be real, just giving someone a drug to lose a bit of weight doesn't do anything for the underlying problem of those people, the fact that they eat too much calorically dense food

@hjewkes Год назад

@Anym the big difference with the drugs is adherence. In the weightloss study, all groups were put in a calorie defecit and worked out for 150 minutes per week, but over a year the control group only lost a few pounds where the groups on the drug lost 30-40. Its not that everyone didnt want to or have to diet and exercise, its that it is a lot harder to stick to the program when your body is constantly sending you hunger signals

@johnd.7606 Год назад

I remember trying this, losing ten pounds because my doctor gave me a simple dose for a month, and then hearing my insurance refused to cover it. It's $1,100 a month without insurance.

@itspossible2015 Год назад

I'd do it. Think of it as spending $300 for a gym membership over 3 months - except with a near guaranteed outcome within a month!

@SolSister10596 Год назад

Ah. So it’s a choice between this or my rent. I’m going to choose my rent.

@hicknopunk 4 месяца назад

Metformin is really good to make you have nausea and generally not want to eat. Cheap too. Heck, talk to diabetics, many will throw the hated nausea pills at you.

@poppingmolly8867 Год назад

I am glad for the positive effects it has for people with diabetes. For someone who struggles with PCOS, it sounds like these drugs could be helpful for that community as well

@LillibitOfHere Год назад

I've been struggling to lose weight my entire adult life. Even when I was counting out 1700 calories a day, full time breast feeding a baby, and cycling hard an hour a day on the road weight was still very slow to come off. The entire older generation of my family is diabetic, I'd be thrilled to take this before becoming diabetic as a preventative.

@rubia12gilable Год назад

That’s why I’m on it. I’m insulin resistant because of the PCOS. I haven’t necessarily lost a lot of weight but I am fuller quicker and my sugars have been better.

@cherylferrer6916 Год назад

I just got diagnosed with pcos and insulin resistant as well. I hope my specialist may help me with what I’m going through. Thank you for this video

@triceyb1363 10 месяцев назад

I have PCOS, and it has helped tremendously. I'm at least 30 lbs down in about 5 or 6 months.

@sattineez 5 месяцев назад

I really wish for it 😢 as a person who has it+hashimoto it could be a great tool

@alexandraalbertz1442 7 месяцев назад

I am at the 9 months mark now on compound semiglutide (Ozempic but not name brand) and I lost 44 pounds so far. From a BMI of 35 to a BMI of 28 so far. Still going strong ahead. I can move so much easier now and work out 4 days a week. I wish everybody the best in their journey to complete health

@CLA45sAMG 9 месяцев назад

This is just amazing, I'm overweight and my doctor prescribed me ozempic 0,25 , i took it this mondau and at the same day i noticed a big diference in my mind, NO HUNGER, you dont think about food , you dont crave burgers pizza sushi etc... Its been 3 day and now must force me to eat something becaus ther is no hunger. I LOVE it thank you to the Scientist that discovered this drug. My bigest problem was controling not to eat fastfood now its like they do not exist

@merrymachiavelli2041 Год назад

The larger-scale implications of this drug (and future superior drugs like it, which are currently in development) could be _massive_ . We are on track for a majority of the worlds population being overweight or obese. All the focus on individuals (either to shame them or celebrate/affirm them) distracts from the fact that this has massive public health implications, which we're dealing with on top of an aging population. The fact is, at a population level, recommending diet and exercise is not an effective strategy. Heath experts have been doing it for decades, and the public health problem is still getting worse. So we need to either radically reform the food industry or our lifestyles (which also won't realistically happen, at least to the extent it would have to), or try to come up with some other method of addressing the fact we aren't biologically wired to live the lifestyles we have. Honestly, this is the most hopeful I've been about actually addressing obesity at scale.

@salioneradam Год назад

@Zaydan Alfariz even Europe doesn't have rules strict enough. We have problems with obesity too. Industry needs to change globally to stop selling calorie-dense addictive foods.

@sizzurpr7608 Год назад

Exactly

@tomashgrey5510 Год назад

Yeah, let's shift the responsibility for our health to a magical pills. Let's get hooked on em. Genius solution 👌

@brickmack Год назад

Most functioning adults don't have these problems. Its not as though everyone under 500 pounds is chaining themselves to a radiator to keep themselves from compulsively eating a whole donut shop, they just... don't have a desire to eat that much. Maybe the correct question, as for drug use, is "why does such a large chunk of the population have such miserable empty lives that eating themselves to death is their only coping mechanism?"

@LafemmebearMusic Год назад

@@tomashgrey5510 that’s not what was said here or in the video but I also hear the validity in your points hyperbolic nature. We definitely shouldn’t be putting our dates in the hands of pharma. AND there’s a real issue that isn’t being solved so this could be a step towards a solution but certainly not the whole solution by a long shot.

@kymberdusmythe930 Год назад

I have found that it also helps with cravings. I'm very glad it exists.

@charlienelson2002 Год назад

A friend is on it, and the results are phenomenal. It works.

@soulqueen3819 11 месяцев назад

I'm amazed it really does work, I been on it for a month and lost 12 pounds already

@iwearleatherjackets1 Год назад

Let's be cautious. New miracle drugs come out all the time and then 10 years later, there's a class action lawsuit.

@puppppppies Год назад

Yup. I'm willing to bet 50 bucks that this is gonna be the next phen-fen

@nilnil7325 Год назад

Thank you for having some sense! This drug doesn't have sufficient long-term data to show it is safe in the long run. The hype that is being created around it is due to marketing and people need to take a step back and look at this whole situation with a healthy dose of skepticism.

@wolfsbane1991 Год назад

This drug has been used for YEARS for diabetes. It's not new, and it's not a miracle drug. It's literally been on the market for decades. Stop spreading misinformation.

@holistichealthhacksinfo Год назад

Why aren't more people realizing this. This comment should have 5,000 likes. Let's revisit this in 2 years and see how all these people are doing. I was borderline type 2 diabetic until I changed my lifestyle. Now there is no diabetes in sight. Wake up! These "quick fixes" will always have side effects and yo yo weight loss/gain is terrible for your health. Learn to get to the root of the problem!

@waltpowell7254 5 месяцев назад

Actually this is not true

@user-cd2ut4fx1m 9 месяцев назад

Love ozempic. Where has it been all my life?!!❤

@BodyWorks123 Год назад

Awesome video! Incredibly useful tips and optimistic tone are truly motivating. Many thanks for sharing your knowledge! 😀

@laurenconrad1799 Год назад

Thank you for this. My endocrinologist prescribed this to me in February 2020. It’s been a wild ride. It definitely did exactly what it was supposed to do, though those side effects are no joke. ❤

@andreymor5201 Год назад

What thyroid issues do you have?

@JayPersing Год назад

@Andrey Mor yooo why are you asking for someone's medical information like it's your business?

@laurenconrad1799 Год назад

@@JayPersing Thanks. Sometimes in comment threads like this one, I’m not sure whether to answer or not.

@PuffleFuzz Год назад

Now the jingle is stuck in my head.

@anaajibicho Год назад

Tried this. Terrible Gastro symptoms that led to panic disorders. Gutted (pun intended) my immune system. Still dealing with side effects two months later. No free ride.

@RebelleFlo Год назад

So sorry to hear that. I hope you’re on the road to recovery ❤️‍🩹. Would you mind expanding on what happened to you? I’m thinking of taking it so would be grateful to hear about firsthand experiences. I wish you all the best 😘

@hicknopunk 4 месяца назад

Metformin is a great nausea pill

@kylecho2912 8 месяцев назад

I’ve just learnt about GI tract and endocrine pathways and this video popped up on my feed I’m so not being monitored lol 😅

@monsterinthedark6519 11 дней назад

My Dad uses this product for diabetes management and it has really helped him. After 2 interviews with the VA I will be taking my first dose next week. I look forward to the help it will give me.

@gregh988 Год назад

It really does make everything easier. Quick advice, inject into your thigh to minimize any nausea, and make sure to drink more water than you usually do.

@madyalvarez428 Год назад

Even outside of just diabetes management and weight loss, ozempic and other similar injections (like Saxenda) are really great for PCOS since it’s functionally like being pre-diabetic!!! Saxenda was just approved by the FDA for use in patients with PCOS, and I have a feeling that Ozempic will be next.

@samanthablevins8009 Год назад

Eating healthy does NOT prevent PCOS! Get educated before you comment to the world on stuff you don't know about

@XhumpersX Год назад

@@samanthablevins8009 You're not wrong there, but you're also incorrect for saying that PCOS is NOT caused by obesity. The two are strongly correlated, but there haven't been any studies that definitively show if PCOS causes obesity, or if obesity can cause or exacerbate the PCOS cyst growth in the first place. The latter would certainly explain the massive rise in PCOS alongside the similarly massive rise in obesity over the past 30 years.

@samanthablevins8009 Год назад

@Afterglow Beats there are many women out there that have pcos and are otherwise healthy and are not obese. I do believe eating healthy helps with every aspect. I just don't want someone speaking out of what seems to be hatred for obese people.

@hicknopunk 4 месяца назад

As a T1D I am telling you not to play with drugs as dangerous as insulin. Just don't. There are better, more obscure meds to make you lose weight. Just limit yourself to 70 to 100g of carbs a day.

@Charrbonic Год назад

This is so interesting to me, especially since my immediate thought is how these might be regulated in the future. Maybe the side effects will do it themselves. I doubt it.

@laustudie 8 месяцев назад

Nice i am buying me some, this makes weight loss so much easier :] Will probably use half the dose though. This makes life so much easier for everyone, really a miracle drug it seems.

@sujaanregme286 Год назад

What a great time to live!

@lauracrawford8723 Год назад

Ozempic really IS A GAME CHANGER. im serious for anyone who struggles with the food issues it actually changed my life, not only did i stop eating a ton of unhealthy food, it made me NOT EVEN WANT the food i desperately craved before, like big time. It’s a fantastic addition to a good diet/lifestyle, it may not be the right decision for everyone, i knew one person where it made them gain weight, but for me and everyone else i know who went on it, it really changed everything. I couldn’t recommend this more.

@sweethoneypot001 Год назад

Thank you for sharing this video! 🙂

@Maxaldojo 10 месяцев назад

Great video! Thanks for putting this out. I am considered morbidly obese and I started Ozempic, today. I was wondering what to expect.

@celinemara565 10 месяцев назад

Are you seeing any good results?

@Maxaldojo 10 месяцев назад

@@celinemara565 The first 4 weeks I am on the 0.25 dose to see how I feel and react (side effects...). So far, rather mild... I was in the hospital twice since November with diverticulitis, so that's my measuring stick. I should know more in a month.

@muzsydful Год назад

Truly a game changer

@rhiannablumberg4803 Год назад

Ty so much for sharing your story

@EmDeePhotography 9 месяцев назад

Usually heart palpitations are caused by too big of a meal. You have to watch the size of your meals.

@vish452 6 месяцев назад

It's a repeating Patten , happened many times in history . This kind of drugs get popular very quickly with only temporary effects ,but cause unknow side effects which are mostly long term or permanent .

@aeonsolo Год назад

I trust your channel and the production value is great. But this one feels off. There is a gap in balance of pro and con. A bit like advertisement. As someone unfamiliar with the subject I might not grasp the full picture here, but that's just the way I felt watching/listening.

@yooo4901 Год назад

very informative video, thank you

@anthonyfcullen6666 Год назад

this is extraordinary

@tralalalalallala Год назад

My father (67 yo, kidney and liver transplanted) is also diabetic, and one doctor made him take ozempic rather than regular insulin. He almost rejected the kidney because of that, vomiting every day, no strength at all, could not drink any liquids.

@aprilmason1616 Год назад

As a soon to be dietician im tuning in for this video (I study in the Netherlands though) Edit: love the video. Good information, short clear and simple, Thank you for making it. I hope people are a bit better informed because of it! Edit 2: the video did miss a couple of important points, other have described it pretty well

@canopus8012 11 месяцев назад

I'm obese and have bad knees and take Semaglutide shot #7 tomorrow, have so far lost 9% of my starting weight, no extra exercise and not dieting at all, i simply feel full all the time, nauseous 2 or 3 times per day everyday but it only last a half hour or so, loose bowel movements almost everyday, i can only afford the next pen as I'm paying full price, but that should be enough to see me to a 12% weight loss - thus will be no longer be technically obese.....Semaglutide is an amazing drug.

@crissiluveslife3802 10 месяцев назад

I’m so grateful

@2btpatch Год назад

The video doesn’t mention the more serious side effects of Ozempic, such as thyroid tumours, but the overview is good. I am a candidate for Bariatric surgery, and I am about to start my prescription of Ozempic. I will just be sure to monitor myself closely for side effects. I tried a trial round of Saxenda (liraglutide) but couldn’t afford to stay on it as insurance doesn’t cover it. Ozempic is a viable alternative and has the advantage of it being a weekly injection instead of a daily one.

@lyndiskenny-howell1323 Год назад

good luck to you as you start your ozempic journey! i recommend having either a zofran prescription or gravol/dramamine on hand, as the nausea in the beginning can be very unpleasant. make sure you drink a lot of water, it reduces your appetite but you also don't really feel thirsty. it's super super important to drink water, (stay hydrated) so don't forget! This medicine has been a life changer for me. i hope you will get to enjoy the same experience as i and many others have had. take care!

@PirateOfTheNorth Год назад

Ozempic was in the news in my country recently because of a shortage

@FOJO27 Год назад

Which country? Just asking since it seems to be in short supply everywhere. (Was assuming you're in the US or Canada)

@marsyplays3s248 Месяц назад

i need this for my insulin resisstance and i hope it helps with that and my weight

@SpikeRosered Год назад

This was very good for me as we just got a memo at work that Medicaid is not covering Wegovy because they don't cover weight loss in general.

@Sophie-ge7ti Год назад

I hope that changes soon.

@therealshard Год назад

I truly hope it's long term safe because (speaking as a 100% non expert) my understanding is that the human body is a complex system and one small change can lead to a cascading of multiple effects. I hope the listed side effects are as far as they go! :)

@kimberlybucoy3420 Год назад

now the jingle is stuck in my head.. again.. Thanks Vox

@aprilmason1616 Год назад

I heard it in this video for the first time, Im not going in a second time hahaha i feel you though ❤️

@sizzurpr7608 Год назад

Ozempic Dreams. I have been on it since last July (2022) then had to stop for 2.5 months in Sept as my coverage ran out. So I gained what I had lost, all back. Back on Ozempic again since mid December w/ higher dosage albeit losing weight slowly. I would lose more lbs likely, if I cut out the sugars & refined carbs. 😬

@JammastaJ23 Год назад

This is awesome for diabetics and obviously there are people that really need this for medical reasons. That said though using this for vanity reasons on otherwise healthy people is kind of a cop out and maybe you should limit your consumption first.

@AngieSimic Год назад

The jingle, if you're under 30, sounds familiar because it's from the Wizards of Waverly Place soundtrack (Selena Gomez song). If you're older, you might know it as the 1974 Pilot song

@FOJO27 Год назад

Ah yes, "Magic" by the band Pilot. How apropos...

@princevalium25 Год назад

I was prescribed an antipsychotic a few years ago for severe depression and it made me gain 80 pounds and gave me prediabetes. I cant seem to lose any weight or improve my insulin resistance. Doc recommended Ozempic of Mounjaro but its nearly impossible to get it right now

@jaguarrior Год назад

Rybelsus is the pill form of ozempic and is a lot easier to get than the injectors. That's what I'm on for my diabetes because none of my pharmacies can get ozempic at all

@redhotsillypeppers Год назад

I'm prediabetic, this is a miracle drug for me but it's hard to get a hold of right now.

@fitforfreelance 11 месяцев назад

I've been covering a lot of this on my channel- always good to get more perspective!

@ScytheNoire Год назад

If almost all people who are obese are at risk of diabetes, then perhaps it would be good to prescribe drugs like Wegovy or Ozempic that can help as a preventative medicine to help obese people lose weight.

@hicknopunk 4 месяца назад

Metformin

@petar4onachev Год назад

This is so popular in Bulgaria, that we have a shortage, making Diabetes patients struggle to find it when influencers are abusing it for weight loss.

@petar4onachev Год назад

@Zaydan Alfariz Yes, years ago we had 24/7 pharmacies at every street corner, after some eu regulation they are non-existant.

@cherrywilson6267 Год назад

What did they do before 2017? Since that’s when this was FDA approved 😂

@tylerpadgett70 Год назад

@vox: "Caution with the rivals the effects of metabolic bariatric surgery" minute 4:45. Expected short-term weight loss following bariatric surgery Operative procedure :: Excess weight loss (percent) Gastric bypass :: 60 to 85 Adjustable gastric band :: 45 to 55 Sleeve gastrectomy :: 55 to 80

@ManOnTheMounjaro Год назад

Excellent video!

@edkwon Год назад

Will be interesting to see what kind of long term side effects manifest once this is widely used for application of weight loss

@inuhundchien6041 Год назад

Yup, you can't stop this the same way you can't stop injecting insulin if you are diabetic, IF you don't change your lifestyle. So for diabetics this is good they just change from one medication to another. For others they are just adding more expenses. I do think it's still good for the initial weight loss but certainly at the same time going to therapy, go to cooking class or enroll in gym to become a 'skinny' person intrinsically.

@edkwon Год назад

@@user-kr6jg6qb7l I'm referring more to unexpected adverse side effects with prolonged use, not the expected effects from stopping use

@adwaitgoku27 4 месяца назад

Where's the advertisement disclaimer?

@Dax888 Год назад

this video has one of the best hooks i’ve ever seen

@andrewreynolds912 Год назад

If this could be used besides for diabetes and as a weight lose treatment could be pretty significant now I know what they said in the vid but were still getting closer to better weight lose solutions

@notapplicable1483 11 месяцев назад

Man, I really think this video misses an important point. While it can help you lose the weight, once you get off it the weight really wants to come back. It’s still mainly up to large life style changes to prevent the weight from coming back. I fear that more and more people are going to become dependent on this for keeping the weight off & won’t be able to get off with out weight gain. Of course this is great news for the drug manufacturers but poor for the normal person that uses it.

@TheAmericanAmerican Год назад

I'm naturally skinny and have been my whole life. It's great. I am super lucky. I want this drug researched even more because everyone should be healthy and comfortable in their bodies!

@YananoBere Год назад

This kind of needed randomly without doing a deep dive into the efficacy of the drug and whether it works long term

@SuperHero-dq4jc 2 месяца назад

One should wonder why we have a weight problem in the first place. What is it in food, portions, sugars, etc. ?

@georgiawidgeon7710 Год назад

I found this very interesting. I am currently using Ozempic that my doctor put me on. It is doing what it's supposed to do for me.

@humancat2434 Год назад

Despite the few caveats at the end, it still felt like video was trying to sell me on a new weightloss drug

@shankar4330 Год назад

My A1c 11.0 went down to 5.1 in just 4 months only through weight loss (40 pounds) without any meds. Do whatever you can and lose that flab for better t2 management

@liltawna12345 Год назад

Me knowing nothing about the drug yet immediately recognizing the jingle from watching Judge shows with my grandma. Not one commercial break goes by without the Ozempic Ad lol

@Megadextrious Год назад

I got diagnosed with thyroid cancer in 2020 and subsequently got a thyroidectomy. My endocrinologist said it would now be nearly impossible for me to lose any weight, so he prescribed ozempic to help me get my bmi down. Super weird I keep seeing videos and news articles about it now…. I hope it works 🤞🏻 😅

@Basement_crusader Год назад

“The drug, crucial for diabetics, is now being trivialized in the mainstream” Insurance companies: 🤔

@healthyinformation 2 месяца назад

never thought of that. You may be right

@nursegege5151 10 месяцев назад

Great info !!!

@healthyinformation 2 месяца назад

yep

@chopstickx 3 месяца назад

Great ad for Ozempic.

@healthyinformation 2 месяца назад

yep

@cyyhey Год назад

Been trying to lose weight all my life. I am finally at a healthy weight through intermittent fasting, regular exercise and yoga. I’m hoping to fast longer eventually for the additional medical benefits as I get older. It’s been a tough tough road.

@SomeDudeQC Год назад

What are the additional benefit?

@tomashgrey5510 Год назад

Good job. Keep it up. Warm hugs from Ukraine

@smallmalaysianboy8025 Год назад

Fasting can be bad for you, all you really need is a calorie deficit. Mathematically you just lose weight if you're in a consistent calorie deficit.

@ASAMB12 Год назад

@@smallmalaysianboy8025 in what way can it be bad for you?

@ASAMB12 Год назад

@@SomeDudeQC the main one I know about is autophagy

@EmilyJelassi Год назад

When my endocrinologist prescribed ozempic to help me with my type 1 diabetes, I was told that there’s a shortage because non-diabetics are taking it for weight loss. While I’m glad that there’s finally something for that, I’m also furious that the medicine isn’t being prioritized for diabetics first! Anything that can help prevent diabetes burnout and at the same time help me lose weight is unbelievably helpful. The idea that this medication is being trivialized into being “just a weight loss drug” is infuriating!!!

@scottanos9981 Год назад

The type 2 diabetics literally got their disease from obesity, the same disease the obese people are trying to treat with ozempic. Diabetics do not have the moral high ground on this.

@jessijoweb Год назад

I was thinking about this too, but if we can cure obesity in people before it becomes diabetes at all, it feels like a win.

@kjkj4725 Год назад

A lot of obese people have pre-diabetes. You can’t blame them for trying to stop developing the actual diabetes.

@royw-g3120 8 месяцев назад

Unless you are overweight Ozempic is not licensed for type 1 diabetes. Your doctor can prescribe it off- license but he should have made that really clear to you at the time.