Panasonic UB-424 drive noise playing Dune 4k BluRay. Yes, I kept it over the PS5 Slim. 

Normally clean both sides of disc.

My ub820 just started doing this with my Dune 4K disc as well. It only happens in the early part of the film. Did you find a solution?

This player has a problem all together! Ive gave up with this model To be honest , Also keep that dander off your console if possible! if it gets in , it screws up the lens i have a cat i have issues all the time with dander myself even with air purifiers. I'm personally using my ps5 now but going to be getting the high tier sony in the next 2 months or so i hate using my console to watch movies because it already takes enough punishment lol .