Peptic Ulcer Disease Pathophysiology 

This is so interesting... I am in the 5th year in Romania, and this is very useful to me. Tomorrow I have a lab exam at gastroenterology, and I must say... NO ONE explained this better than what I've seen in this video... and teachers are paid to do that (not paid enough). Thank you so much.

this is quite seriously probably the best, simple and very clear presentation i've seen on youtube. lots of compliments to you!!!

Sir i've been watching ur videos since 2012 they are rlly helpful, i got high grades thanks to you )!I'm a med student on my 4th year now and with every new course i have to check one of your work before i even open a book ;) thanks for putting the effort and god bless you

I absolutely cannot without your videos sir Wolf. Greatly explained in detail. Thank you very much

Thank you for a very detailed and insightful look into physiology and pathology of peptic ulcers . Ive been very interested & studying gastroenterology along with histology and this puts it in perspective for those who want to look deeper into the mechanistic pathology ❤🌅❤

Thank you for the knowledge you hav provided me with...i hav to give a seminar on dis topic tomorrow in my class, it's very helpful. Thank You for the efforts. Looks like I don't need to do anymore research. I have everything I need. Even my reference book doesn't tell me this much. Thank You Again.

Thank you so much for making this topic much easier for me to understand. It shaved off so much time in my review for upcoming exams. 😊

All day I'm watching ur videos :) and I'm very grateful...best medical media !!!

Thanks for an excellent presentation. Very clear, informative and easy to follow. I appreciate your revision at commencement.

THANK YOU ANDREW! Your presentation is always super informative. It is helping a lot with my NP degree

Great explanation,. Though I think gastric ulcer and duodenal ulcer pathophysiology should be explained together + duodenal ulcer is more common, so I would appreciate more details about that too, since it's important. Thanks anyway for this! :)

Thank you for this informative and educational piece on Peptic Ulcer Disease! It was very helpful and easy to understand.

Thank you for all that you do.

im 4th year med student, study in romania, the teachers are useless. what i learned from you in 29 min is much more than what i've learned through the whole digestive stagiu

Thank you so much for your time and dedication!

Great video. Would appreciate a picture of the whole flow chart for easy revision

amazing video so helpful for my pharmacy course!!!

Great video ! Thanks for the breakdown!

Great video. Would appreciate a picture of the whole flow chart for easy revision. Also h2co3. Again, great video. Thanks

It was great help ! I wonder if you do videos on the pharmacology of the drugs based on the pathophysiology of the diseases?

Excellent lecture. Very helpful. I realize though that you did not say any thing about how stress and sympathetic stimulation causes stomach ulcers. Do you have any video on that deal with it ? If so please let me know .

thanks for making it easy to understand

You are a life saver . THANK YOU MUCH

thank you so much it was so easy explanation 👏🏻👏🏻👏🏻

your videos very helpful andsuperb

thanks alot dr. realy i understand it very well... god pless u

Simply amazing...!

Amazing, Thank you! 🎉

Thank you Mr. Wolf. Your videos are amazing and so simple :)

Hi, great video - you really simplify and present it in a clear way. I have 2 questions: 1. From what I read H pylori decreases acid secretion, as opposed to increase in acid secretion as you mention. 2) I did not find a recent article supporting the surfctate layer, can you please send a few studies about this? Thx!!

a very well said dr! thanks a lot!

Please put subtitles on this video that are accurate, trying to learn key terms from this video is improssible when they arent spelt correctly.

great explanation

Hi, today I had an exam and the question was “how does alcohol affect the mucosal layer for gastric ulcer making?” So I talked about the surfactant. My teacher said that there’s no evidence of that on the GI track, just on the lungs. So I wanted to know what was the biography of that statement.

Hi thanks a lot for the educative information. it really prepares me for my exams. Would you please inform me more about the pathogenesis of the disease. is it just through the same way as the peptic ulcer disease

Excellent presentation

Hello Andrew Wolf: Thanks for this fascinating video. I remember from my lecture days in nursing school. One question: do you have any information on gastritis relating to diabetes? Also, can you discuss the chemistry related. Thanks again.

watch in 1.25 speed!

I like the video. Very informative. A bit long for my taste.

Helpful lecture,Thank you!

Thanks so much

Thank you so much!

Informative Thanks :)

give a video for pharmacotherapy nd treatment with site of actions including side effects and precautions plzz..

thank you! awesome vidoe

great videos but alot of spelling errors, students who have not studied GIT may think that all the spellings are correct.

Why didn't you mention the role of prostoglandins when you talk aboit the protective mechanisms ?

nice one ! thank u ! 😀

Hi thanks for an interesting and informative video. What treatment would you recommend for h pylori?

thanks alot doctor!

enjoyable teaching

How bout vids on Pharmacology also? :3 Anyways, thank you and cool vids! Have learned more than when I am in class!

Awesome👍🏻

Mr. Wolf, isn't the point of having enteric coated Aspirin to prevent digestion of the aspirin in the stomach, but rather in the small intestine? I saw you mentioned that as one of the etiologies of PUD. Wouldn't uncoated tablets cause more harm?

I think you explained Delta cells wrong. They are stimulated by inc pH

Thank you sir🙏

Great

Very helpful video. Thanks a lot :D

Thank you! Your videos are really helpful! So do NSAIDS increase the risk of an upper GI bleed as they can cause peptic ulcers, or is there another way that they can cause it?

Thank so much

thank you very much sir. u are my star :-)

what does mean of apical adaptation ...? tell clearly about mucosal barrier how it protect and how it induce to cause peptic ulcer ...?

Did i get this right ? Hp causes inflammation ..the same infly cells stimulate G but destroy D cells?

gud video ! Is it that the most potent stimulus for H+ secretion is when the food reaches the antrum (G cells)....but the parietal cells are mostly in the body ? so how does it help?

Please, what is the difference between pathophysiology and pathogenesis?

Mr. wolf, about somatostatin does it inhibit G-cell OR Parasympathetic release of ACH as you said?! and thanks in advance

hey, ive read in my book that one cause of PUD is the back diffusion of HCl? Can you elaborate on this more please. I don't understand where HCl diffuses back and what the book means by back diffusion. thanks.

That was a great video.. Butttt. Why u talk so slowly and suddenly become louder!!!that was irritating

Very informative ..... Thank you.

Thank youv💜

Ive been on Prilosec and Paxil for 21 yrs and recently have tapered down on both and my duodenum/small intestine aches, maybe ulcer so I may have to go back on the normal dose, seeing as Ive been taking Prilosec for 2 decades Im worried about Gastrin levels and stomach cancer risk from taking PPI's long term and yet when I reduce slightly my proton pumps awaken and my duodenum doesnt like it one bit, I was thinking about taking DGL, cabbage juice, yoghurt etc whilst Im coming off Prilosec to protect the stomach/duodnum lining, are there any other things |I can do to help the stomach/duodenum to adjust to stopping PPI's, I thought maybe start taking Gaviscon which coats the lining? Thankyou.

thanks

great

please i did not understand about the mucosal barrier ????

So... PUD = Gastric ulcer disease = duodenal ulcer disease?

Bless you

I want refernce material of this video

Wonderful lecture... bt u change your tone n pitch after every few seconds.. dat becomes bit irritating n caues loss of interest...

nice

Good information! But you talk very very slow, try to talk more enthusiastic next time, maybe?

I thought COX 3 isn't functional in humans?

nyce

doc hi nice information i have a question if activation of parasympathic nerves system lead to release more of ach and we know the parasympathic are activate under relax time sleeping time but how stress can give ulcer too

👍

👏🏻👏🏻

Sir you are ready lazy to talk...it interrupt the understanding 😞

Lk NH i

Boring lecture

thanks