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Pernicious Anaemia : Definition, Pathophysiology, Clinical Features, Diagnosis, Treatment (HD) 

Rabiul Haque
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Topics Include:
- What is Pernicious Anaemia
- Pathophysiology of Pernicious Anaemia
- Genetic Factors
- Auto Immune Factors
- Antibodies Against Parietal Cells
- Antibodies Against Intrinsic Factor
- Blocking Antibody and Binding Antibody
- Site of Gastric Atrophy
- Clinical Features
- Lab Diagnosis
- Schilling Test
- Blood Picture
- Bone Marrow Findings
- Treatment and Dosage of Deep Subcutaneous/ Intramuscular Vit B12 Injection
Hope it is helpful . - Dr. Rabiul Haque

Опубликовано:

 

8 июл 2024

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Комментарии : 97   
@esterherschkovich6499
@esterherschkovich6499 3 года назад
Oh gosh hate the getting old bit!I work as a Nurse+its hard going,need injections 2 monthly..fatigue!Thank you for your explanation.
@RabiulHaque
@RabiulHaque 3 года назад
Thank you madam for your feedback. Take care and stay safe. Best wishes from Bangladesh.
@elainec.s.1275
@elainec.s.1275 8 лет назад
Thank you Doctor. Will listen to other video's. I have pernicious anemia and the B 12 def. I was in my early 30''s when it was found. When you mentioned the thyroid factor. It is in my family. I am trying to find out why I need to inject every 8 - 10 days. Again, than you so much.
@rishikagupta2110
@rishikagupta2110 4 года назад
u r the best teacher pls keep uploading videos ....in 2020 also ur lectures are helping me n many more medical students
@RabiulHaque
@RabiulHaque 3 года назад
Thank you for your feedback. Take care and stay safe.
@esterherschkovich6499
@esterherschkovich6499 3 года назад
Why put thumbs down?,When it's an informative video!
@taooflovepassionandcomedy8722
@taooflovepassionandcomedy8722 5 лет назад
Thank you young man I shall have some very stern words with my doctor you have told me some thing no Doctor in Australia has ever mentioned.
@RabiulHaque
@RabiulHaque 5 лет назад
Thank you for your feedback. Take care and stay blessed. :)
@XRPVampire
@XRPVampire 4 года назад
Bravo, well done!
@laila5597
@laila5597 6 лет назад
جزاك الله خيرا
@RabiulHaque
@RabiulHaque 6 лет назад
Thank you for watching my videos and for your feedback. Take care & stay blessed. :)
@sweetys3266
@sweetys3266 9 лет назад
Thanks you Dr. Rabiul!
@RabiulHaque
@RabiulHaque 9 лет назад
sweety sharma Thank you for liking my videos. Best wishes from Bangladesh.
@sumitasingh6225
@sumitasingh6225 8 лет назад
Doing great job God bless you
@RabiulHaque
@RabiulHaque 8 лет назад
+Sumita Singh Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)
@PrinceKumarsHere
@PrinceKumarsHere 3 года назад
Thanksss a lot sirr.. from AGMC student
@paraymuzafar1724
@paraymuzafar1724 3 года назад
very nyc May Allah Bless u
@coolameloblast
@coolameloblast 3 года назад
Thanks
@RabiulHaque
@RabiulHaque 3 года назад
Thank you for your feedback. Take care and stay safe.
@durgachalise5661
@durgachalise5661 4 года назад
Thank you sir....
@felixkamugisha4647
@felixkamugisha4647 7 лет назад
Thanks Dr Rabiu for your nice teaching videos. God bless you abundantly! Fr. Dr. Felix
@RabiulHaque
@RabiulHaque 7 лет назад
Thank you for liking my videos. Best wishes from Bangladesh. :)
@dr.praveenkumar9392
@dr.praveenkumar9392 4 года назад
Thanks sir
@lindadahlen7407
@lindadahlen7407 4 года назад
Your explanation is very thorough. Thank you very much. It will help with my treatment plan of PA diagnosis and other autoimmune issue going on. I have senile osteoporosis also at age 59. Now I know the relation of osteoporosis, high calcium in my blood and hyperparathyroidism. I will talk with my doctor about this correlation. Thank you again!
@RabiulHaque
@RabiulHaque 4 года назад
Thank you for your feedback. Take care and stay blessed. :)
@onlyoneboss
@onlyoneboss 8 лет назад
very helpfull vdeo..thnks sir..frm india
@dr.mjwesley6691
@dr.mjwesley6691 7 лет назад
Awesome job. I'm preparing for board wanted to go through haematology real quick. Your videos helped me a lot. Every point is very crisp and clear. Please keep uploading more. Thank you so much for making it, Thank you for making it free as well. God bless you!
@RabiulHaque
@RabiulHaque 7 лет назад
Thank you for liking my videos, best wishes from Bangladesh. :)
@shahriar6180
@shahriar6180 8 лет назад
this is just awesome!! thank you so much..
@RabiulHaque
@RabiulHaque 8 лет назад
+shahriar Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)
@paraymuzafar1724
@paraymuzafar1724 3 года назад
nycc very Good❤️❤️
@beenaasokan8569
@beenaasokan8569 7 лет назад
thank you. it helped me a lot in immunology paper.
@RabiulHaque
@RabiulHaque 7 лет назад
Thank you for liking my videos. Best wishes from Bangladesh. :)
@mwazanjibanda2315
@mwazanjibanda2315 Год назад
your lessons are super helpful, I understand everything clearly when you tech...thank you very much
@RabiulHaque
@RabiulHaque Год назад
Thank you for your feedback, take care and stay blessed.
@drswetaruparel
@drswetaruparel 5 лет назад
Thanks a lot!!!
@RabiulHaque
@RabiulHaque 5 лет назад
Thank you for your feedback. Take care and stay blessed. :)
@smitasimi1190
@smitasimi1190 9 лет назад
Thank u Dr Rabiul
@RabiulHaque
@RabiulHaque 9 лет назад
smita simi Thank you for liking my video. Best wishes from Bangladesh. :)
@karmadoma9687
@karmadoma9687 6 лет назад
This was very helpful 😊
@RabiulHaque
@RabiulHaque 5 лет назад
Thank you for your feedback. Take care and stay blessed. :)
@surenderjanagal7
@surenderjanagal7 3 года назад
Osm sir 👌👌
@RabiulHaque
@RabiulHaque 3 года назад
Thank you for your feedback. Take care and stay safe. Best wishes from Bangladesh. :)
@SJonny-zo3qe
@SJonny-zo3qe 8 лет назад
thanks sir
@RabiulHaque
@RabiulHaque 8 лет назад
+SK Iftakharul Alam Thank you for liking my video. Glad to know it was helpful. Best wishes from Bangladesh. :)
@laila5597
@laila5597 6 лет назад
your lectures are really helpful - greetings from UAE
@RabiulHaque
@RabiulHaque 6 лет назад
Thank you for watching my videos and for your feedback. Take care & stay blessed. :)
@PoojaPatil-qz3tv
@PoojaPatil-qz3tv 3 года назад
Thank you so much sir.... Your videos are really very helpful.. 😇
@RabiulHaque
@RabiulHaque 3 года назад
Thank you for your feedback. Take care and stay safe. Best wishes from Bangladesh. :)
@nuzhatnowshin6957
@nuzhatnowshin6957 8 лет назад
thank you sir ...it was really helpful :)
@RabiulHaque
@RabiulHaque 8 лет назад
+Nuzhat Nowshin Thank you for liking my video. Glad to know it was helpful. Best wishes from Bangladesh. :)
@srirambhardwaj2343
@srirambhardwaj2343 4 года назад
Thanks.a.lots.
@RabiulHaque
@RabiulHaque 4 года назад
Thank you for your feedback. Take care and stay blessed. :)
@ninjanicnic
@ninjanicnic 6 лет назад
Pretty good but not all PA will present mesoblastic and glossitis or nerve damage /neuropathy. Also as in all autoimmune patients may not have antibodies at time of test but may develop later or not but still have PA . Gene mutation may be cause . Loading doses should be until no further symptoms. The monthly or 3 monthly is not enough for reversal of symptoms or healing nerve and tissue damage. The maintenance dose is just enough to keep the person alive but with no energy and still in chronic pain . Shillings test no longer done . Look at active B12 tests for all low B12 (non diet related) MMA homocysteine and to a degree MCV (but this may rise and fall with other factors and not always be high Evan with a diagnosed PA) Better than some information but still flawed .
@phurbutsering1128
@phurbutsering1128 9 лет назад
Thank you for the great video. Helped me understand pernicious anemia for my exams
@RabiulHaque
@RabiulHaque 9 лет назад
Phurbu Tsering Thank you for liking my video. Glad to know it was helpful. Best wishes from Bangladesh. :)
@srirambhardwaj2343
@srirambhardwaj2343 4 года назад
Thank.you.very.much.sir.
@RabiulHaque
@RabiulHaque 4 года назад
Thank you for your feedback. Take care and stay blessed. :)
@docnature9289
@docnature9289 7 лет назад
i would like to suggest u sir to go through all points mentioned in harsh mohan book of pathology... it will b very helpful for us then.. thanks for teaching us sir !
@hmmmmankind2399
@hmmmmankind2399 7 лет назад
thankyou sir
@RabiulHaque
@RabiulHaque 7 лет назад
Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)
@niamaali9534
@niamaali9534 Год назад
Really helpful video... thank you sir🤎🤎🤎
@RabiulHaque
@RabiulHaque Год назад
Thank you for your feedback, take care and stay blessed.
@10dubious
@10dubious 8 лет назад
Thank you so much for making these videos! I am currently taking a course on the pathologic basis of disease and your videos have helped so much. You are a great teacher and I sincerely appreciate your generosity in sharing these videos with all of us.
@RabiulHaque
@RabiulHaque 8 лет назад
+Dubious Observer Thank you for liking my video. Glad to know it was helpful. Best wishes from Bangladesh. :)
@paraymuzafar1724
@paraymuzafar1724 3 года назад
thnkuuuuy
@norxgirl1
@norxgirl1 10 лет назад
good info....from what I am learning, folate/folic acid, which is in most processed foods these days, can mask a Vitamin B12 Deficiency. Please see Sally Pacholok's _Could It Be B12?_
@drsaikatchakraborty
@drsaikatchakraborty 5 лет назад
Folic acid is vitamin B 9 needs to pregnancy and without it abortion may take place
@saahilkhan1150
@saahilkhan1150 6 лет назад
Sir u r great ,long live sir love from india ,plz upload more and more videos
@RabiulHaque
@RabiulHaque 6 лет назад
Thank you for your feedback. Take care and stay blessed. :)
@gautamil20
@gautamil20 5 лет назад
He didn't talk about one more C/F which is Dyspepsia as a result of achlorhydria .Achlorhydria occurs because of reduced HCL production as there is gastric atrophy of parietal cells and we know parietal cells secrete HCL hence achlorhydria and thus Dyspepsia. :)
@drnavneet6594
@drnavneet6594 7 лет назад
nice class sir from india
@RabiulHaque
@RabiulHaque 7 лет назад
Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)
@mahnazashrafi2530
@mahnazashrafi2530 9 лет назад
thank you from italy
@RabiulHaque
@RabiulHaque 9 лет назад
Mahnaz Ashrafi Thank you for liking my videos. As always, best wishes from Bangladesh. :)
@charrison58a
@charrison58a 8 лет назад
thanks for the info. what have you known that a person has taken other than b12 injections.
@aliciamilam5636
@aliciamilam5636 2 года назад
Wonderful man u are . Can u cover herbs for these anemia.. rosemary helps with pain.. for ssd.
@amulyakandukuri504
@amulyakandukuri504 8 лет назад
Hi sir coukd u explain disorders of leucocytes and lymphoreticular tissues
@purposewithoutlimitstv3522
@purposewithoutlimitstv3522 2 года назад
Thank you. How long does it take for B12 supplementation to see healing in the nerves and motor and sensory function? Year?
@ohgreat3363
@ohgreat3363 6 лет назад
is there microbiology and pharmacology videos like this PLEASE HELP
@drsaikatchakraborty
@drsaikatchakraborty 5 лет назад
Sounds are not so loud. Some ward's missing. Pls write more bigger some words are too small to read. Thanks for your videos.
@RabiulHaque
@RabiulHaque 5 лет назад
Thank you for your feedback. Take care and stay blessed. :)
@subhajitbiswas7630
@subhajitbiswas7630 10 месяцев назад
Autoimmune gastritis blood test sujjest ana test sa pata chal sakta hain kay
@spinach5204
@spinach5204 5 лет назад
Very nice video! I just want to know what sources you used for this video?
@RabiulHaque
@RabiulHaque 5 лет назад
Thank you for your feedback. I took help from Robbins & Cortan Pathologic Basis of Disease 8th edition, Harsh Mohan Text Book of Pathology 6th Edition, De Gruchy's Clinical Haematology in Medical Practice 5th edition etc. to make this video. Take care and stay blessed. :)
@RabiulHaque
@RabiulHaque 5 лет назад
Thank you for your feedback. I took help from Robbins & Cortan Pathologic Basis of Disease 8th edition, Harsh Mohan Text Book of Pathology 6th Edition, De Gruchy's Clinical Haematology in Medical Practice 5th edition etc. to make this video. Take care and stay blessed. :)
@khalidashouk5573
@khalidashouk5573 10 лет назад
Well done Dr. you are doing great Job, but try to use power point and animations available , or make your own animations. best regards from another Dr
@RabiulHaque
@RabiulHaque 10 лет назад
Thank you Dr. Ashouk for liking my videos & for your suggestions. I do have plans for making some small duration videos where I will use powerpoint. But for my long duration videos I will continue using white boards as my students feel like they are actually in my class by doing so ( I started uploading to youtube when my students could not come to medical college for political crisis). Take care & stay blessed. Best wishes from Bangladesh :)
@everydaydissociation
@everydaydissociation 9 лет назад
***** Yes sir I too prefer the white board and marker
@taloolalady0not
@taloolalady0not 8 лет назад
Yup, keep that white board- its more engaging than a plain old picture.
@drhamdaankhan3691
@drhamdaankhan3691 5 лет назад
Sir, plz kindly change your white board...good lecture.
@RabiulHaque
@RabiulHaque 5 лет назад
Thank you for your feedback. I have addressed the white board issue in my newer videos. Take care and stay blessed. :)
@vyomsingh1179
@vyomsingh1179 7 лет назад
sir i come to know about B12 deficiency or meghaloblastic anemia in 2011 but i suffered before this a lot .... bcoz of this diagnosed later.... i am taking ayurvedic medicine for that including panchkarama.. my highesht hb is 11.7 mg/dl.... when i take proper diet .... but i am suffering from gastric problems .... i used to take b12 tablets quarter a year... 10 tablets... i want to know what more i can do to live healthy.... how can my hb reach normal... my age is 30yrs....
@totanshit9341
@totanshit9341 3 года назад
Sir please make hindi.
@sukantachakraborty9950
@sukantachakraborty9950 7 лет назад
Why Pernicious Anaemia is rare before the age of 30?
@Yogaasambandam
@Yogaasambandam 5 лет назад
Thank you sir
@RabiulHaque
@RabiulHaque 5 лет назад
Thank you for your feedback. Take care and stay blessed. :)
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