Pharmacology - ACNE TREATMENTS (MADE EASY)

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Acne is a multifactorial inflammatory disease that affects the skin's oil glands and hair follicles. Current acne treatments target the three main factors leading to breakouts: excess sebum production, bacteria growth, and clogged pores. This pharmacology lecture covers topics such as pathophysiology of acne formation, overproduction of sebum, follicular hyperkeratinization, the role of P. acnes bacteria, genetic & hormonal influences (the role of estrogen and testosterone), mechanism of action and side effects of common acne treatments; retinoids, pertinent antibiotics, and hormonal therapies. Drugs mentioned include; Tretinoin, Adapalene, Tazarotene, Isotretinoin, Sulfamethoxazole, Trimethoprim, Clindamycin, Doxycycline, Minocycline, Erythromycin, Azithromycin, Benzoyl Peroxide, Spironolactone, and Oral Contraceptives; Ethinyl Estradiol, Norgestimate, Desogestrel.
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0:00 Acne pathophysiology
3:12 Retinoids
5:55 Antimicrobials
8:31 Hormonal therapy

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2 июл 2024

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Комментарии : 232

@marcusmassoud995 3 года назад

i promise you clearing up your acne feels so amazing and gives you the biggest confidence boost. i was struggling for years and it finally cleared up and i feel amazing. you got this

@therareexperiments2090 3 года назад

What did you do?

@marcusmassoud995 3 года назад

@@therareexperiments2090 differin

@alexisesparza3453 3 года назад

@@marcusmassoud995 quick question I just started it. What products do you use with it

@hdog2967 2 года назад

@@marcusmassoud995 Does it actually last?

@marcusmassoud995 2 года назад

@@alexisesparza3453 gentle products like cerave and no exfoliatns

@MarinaAndTheDevil 4 года назад

Finally someone actually explained what is happening to my face

@bluecityfoundation-robahhf5698 4 года назад

yea sure me to -- This article changed my life www.youngclear-skin.com/blog/how-get-rid-period-acne-overnight-and-prevent-acne-flare-ups/

@marrypoppins6278 3 года назад

Welcome to pharmacy 😂😂😂

@Slyracoon666 3 года назад

Take a shower

@MarinaAndTheDevil 3 года назад

Obito lmao

@chad2208 3 года назад

@@Slyracoon666 not how it works

@fslayer1290 2 года назад

When I started using retinol I had no idea it could help with acne; I was using it to even out my skin tone. When the breakouts stopped I was pleasantly surprised and incredibly thankful.

@Alice-fw2pu 2 года назад

U used to have acne , like much or mild ??? How many days did it take ?? Can u please explain 😔

@navjotkaur4611 4 года назад

Excellent.This video tells me the whole story of acne very clearly.GOD bless you.

@mariemorris5979 3 года назад

This was a short but informative guide. I would recommend this acne guide *AcneCureOnline. Com* to my friends starting out on their journeys to clear skin, getting rid of acne. Greatly liked this and loved the understanding into how my inside troubles can affect my skin.?

@rachellarsen5612 3 года назад

This acne guide *AcneCureOnline. Com* was very informative and helpful. I often go through gentle adult acne and this guide discusses all the possible solutions for mild to severe acne whether natural procedures or otherwise. I prefer the natural way of treating them and I found out on this guide the treatments that work efficiently.

@gargideka 3 года назад

Finally a video that really explains everything that needs to be explained

@krissymichele 4 года назад

The most informative acne video I’ve ever seen and I’ve watched a LOT!! Thank you for keeping things clear and to the point. The visuals helped greatly as well. Thank you so much.

@Biomeducated 4 года назад

This channel is awesome! There's a reason why I included you in a Top 10 Biomed channels! Glad you uploaded again. This particular video (sadly enough) takes me back to my youth in a bumpy way...great explanation. Cheers from Belgium!

@missgracyy22 4 года назад

YOU ELUCIDATE THE FACTORS VERY WELL. Excellent!!!

@Saadalsaeedi 4 года назад

Liked before watching

@rimah694 2 года назад

Finally a video that actually explains the mechanism of action of retinoids. Thank you. Very well explained.

@julesexequielsuico5680 4 года назад

Wowww very nformative... I'm overwhelmed

@Mariah-ge5be 4 года назад

Ma fav channel till now 👌❤

@lexiepetite8634 Год назад

My dermatologist is incredibly reliable and a respected professional, but she just took 1 look at me and prescribed 1) Epiduo (Adapalene + Benzoyl Peroxide ) 2) Clindamycin 3) Oral Hormonal Therapy 4) Blood Tests to change Hormonal Therapy to a stronger one (the Pill) if needed WITHOUT ANY EXPLANATION, I wish she told me what these products are supposed to be doing. Thank you for your explanation, now I understand I need to be patient with redness, irritation, itching, peeling etc, as they’re a normal part of healing!! :D (I’ve only been doin this treatment for a month, but I can really see my acne calming down and reducing to small spots where it was less severe, now I just need to le patient and wait for my skin to regenerate like it’s supposed to)

@demekeeligo64 2 года назад

Thank you so much. Only in 12 minutes you cover every thing

@meetthemasters754 3 года назад

Hey, VERY VERY GOOD MY MAN! Appreciate the effort and technical explanation

@stephlemus9448 4 года назад

I really enjoy your videos!!! Such an amazing job! Thank you!

@moonspy3249 2 года назад

I appreciate your video sharing with us so much, as I’m medical student I suggest this video to my friends

@user-cm4si2sf3m 4 года назад

Amazing animation and amazing explanation

@jobcare7034 Год назад

Wow I was just astonished to watch these exclusive informative videos, I have ever seen the best. Thank for more details of acne causing qnd treatment.

@sssal6022 4 года назад

Amazing video. Explained so much.

@SS-fd8kh 3 года назад

Great explanation, thank you!

@robmoore2209 3 года назад

Thanks so much! This is a wonderful service

@ThatJPGamer 4 года назад

This was so informative and well presented! As someone who struggles a lot with acne I really appreciate being able to learn about it in a more scientific way. Would you ever consider making more skin care videos? For example, how retinoids work for anti-aging or maybe on different sunscreen filters and their mechanisms :)

@dnnnforfordnnn7838 3 года назад

I don't think this channel was made for skin care, I think this is for medical or pharmacology students.

@joyjuly5390 2 года назад

I recommend you to watch the budget dermatologist for acne skincare i find her more informative about skincare ingredients that fights acne and improve skin

@reebaqureshi7068 3 месяца назад

Best video till date on pharma ❤️

@woloabel 3 года назад

Great illustration and explanations....

@pharmamadeeasy1880 4 года назад

Thanks to speed pharmacology channel for giving us such a wonderful knowledge to us! sir you really are making pharmacology so easy ! #PHARMAMADEEASY

@ilayRA100 4 года назад

Wonderful explanation! Thank you! :)

@howtomedicate 4 года назад

Amazing animations! Really good video 👍

@btaylo24 4 года назад

Very interesting and well explained.

@iltaffrauff627 4 года назад

Amazing,.... Looking forward to anti- virals,.....

@Nooniloonies 2 года назад

Such useful insights thanks for creating such informative video

@supernova9886 4 года назад

Keep going!! U r great

@AngeloTelesforo Год назад

Great content! Your clip art is amazingly good, fun and accurate! That is great for memorization. Are they produced by you or are they from any available source. I’d love to use them in my classes!

@pemachoki1647 4 года назад

Please do a video on anti tuberculosis,migraine and hormone related drugs

@yashowofficial7303 4 года назад

Thanks for your good explanation it's clearly now every one can understand now thanks but plz add more details

@eclkt 4 года назад

Thank you for your education.

@julynmaepeteros3307 3 года назад

Thanks very informative video.

@saritapal9662 2 года назад

Very nice sir, Thank you

@mar1na1993 3 года назад

I never had to deal with acne during puberty, but I’m now in my mid/late 20s and my face just doesn’t want to cooperate! Now I understand a little more about how my tretinoin and clindamycin work together to treat my acne. I just have to be patient...

@dustingalbraith5369 2 года назад

ive been using both for years and to be honest it works and the zits come back again cause they gain resistance. its all in the genetics in my opinion but it definitly helped prevent worst case acne

@elchinn87 3 года назад

Excellent..

@heiitsme182 3 года назад

Thank you for the explanation

@yourmother9834 4 года назад

This is exactly what I needed. My dermatologist just prescribed me to use facewash with benzoyl peroxide, clindamycin and tretinoin. Thanks for explaining it in a way that makes sense!!!

@ElfPk3r 3 года назад

Hey! How is your treatment coming along? Any progress?

@yourmother9834 3 года назад

Fallen, Yes! My face is clear it worked. I love it, my pores are less visible as well

@ElfPk3r 3 года назад

@@yourmother9834 glad it worked out for you! Can I ask what your routine was? Did you alternate Tretinoin and Clindamycin on different days?

@yourmother9834 3 года назад

Wash my face twice a day so ill explain morning and then night CeraVe 4% benzoyl peroxide and clindamycin wipes in the morning with CeraVe 30 spf moisturizer. At night, wash with CeraVe 4% benzoyl peroxide and then after i use the tretinoin mixed together with CeraVe night time moisturizer. I had to work up from once every 4 nights tretinoin to every night slowly it took a month to get to where I was using tretinoin every night

@yourmother9834 3 года назад

So you cant use both prescriptions at the same time so it’s clindamycin in AM and tretinoin with moisturizer at night

@jaikumar-bv2oc 4 года назад

most informative video on acne problem..

@scottwendell7128 3 года назад

I am in my 40`s and just began with adult acne. It got seriously bad!! I didn`t experience acne before. After applying this acne guide *AcneCureOnline. Com* for 2 weeks, I observe obvious effects. I am trying this treatment for 2 months now and have become comfortable once again. .

@Janice3349 4 года назад

You're excellent

@FknNefFy 3 года назад

Excellent. I only wish more RU-vid videos were as informative and factual as this one. well done thank you🙌🏻

@MrPaulrael 2 года назад

Very informative

@tusharmishra9995 4 года назад

Please add more details if possible. Good work ..

@markbliss8264 2 года назад

Guys like the vid so he gets the credit he deserves

@amberswartz3876 4 года назад

Really informative video! Thanks for putting this together. Also your information design was great 👌 I didn't know all the big words but I was able to follow enough to grasp the concept, I think the imagery helped!

@scottwendell7128 3 года назад

There Is an Overload of Conflicting Information and Often Ineffective Advice on How To Treat Acne. While it took little less than two months for me to really see a difference, my acne, blackheads and whole lot of other skin problems I had…such as eczema… had completely cleared! It was totally amazing. Permanently Cure Your Acne Within 2 Months. Here > *AcneCureOnline. Com*

@nanwijanarko1969 3 года назад

That's true, this is also out of my depths of absolutr understanding. But the visuals really helped in telling what is going on.

@Bromocriptine777 4 года назад

THE BEST

@Haprijoy 4 года назад

Sir please upload immunosuppressant and anticancer drugs

@happyheart8888 3 года назад

Thank you

@bazil5250 2 года назад

Thanks. How about PFB? would you consider doing a video on it?

@nilak.s617 4 года назад

So, how do I find out the size of my sebaceous gland?

@mayuri2365 4 года назад

Explained in an Outstanding way..plz make the similer one for all anticancer agents..

@sharonambrose 3 года назад

I had terrible acne from my teens until my 30’s. Changing my diet is the only thing that worked-I went paleo and the acne is gone!

@meenamee9774 3 года назад

Hi Sharon... I too have the same problem.... Can u give me few tips?

@sharonambrose 3 года назад

meena mee Hi Meena, we are all different but for me my diet was the culprit. I did an elimination diet called the Whole 30 for a month then I transitioned to Paleo. Basically I cut out dairy, grains and sugar. I think dairy mostly added to my acne trouble. Acne was so frustrating for me, it got super bad after I had my first baby but thankfully the diet cleared me up after years of trying all the topical creams. I wish you so much luck on your journey.

@happyheart8888 3 года назад

I am on my 30's still have acnes.. sad

@hutashani 3 года назад

@@happyheart8888 having acne is not bad thing...that means your skin still produce oils...and that's not bad for aging ...try to find skincare products and food which suit your skin☺️

@shironamhinavash9561 4 года назад

Sir May Allah bless you♥♥

@Shahnawazkhan-hh8er 2 года назад

thank you sir 👍👍

@rajivdas8185 4 года назад

Good 👌

@lafbrito 3 года назад

I’m surprised azelaic acid wasn’t mentioned as an antimicrobial... very good video tho

@llamaliammm 3 года назад

Can you do one on epidermal and dermal hyperpigmentation and PIE?

@Radjehuty Год назад

Hmm this is somewhat confusing on the retinoid section. It's mentioned and it's true that retinoids have to be converted to retinoic acid but the examples given I believe aren't part of that situation. Tretinoin is already bioactive retinoic acid. Adapalene and Tazarotene are both third generation retinoids that are already bioactive even though they're not retinoic acid, but they do bind to the same sites. I was hoping to get some information on what the key differences are in the pharmacology between tretinoin and adapalene.

@zainabhuzefa9529 3 года назад

THANKYOU THANKYOU THANKYOU

@barbaraboisclair8788 3 года назад

This also happens to women that are menopausal see them goes up oestrogen is gone I ended up with folliculitis and prurigo nodularis. My doctor said this is my new reality this horrible crap leaking on my head when in fact I asked him to put me on Accutane because I had used it years before and it seems to be helping

@aquaticlivemalayalam5601 3 года назад

My dermatolagist prescribed me clindamycin +adaplene gel.

@kneeckle8312 4 года назад

Can u please do a video about drugs used for ADHD?

@thodorosasteriotis545 4 года назад

Keep it up

@oguntadeoladayorauf4657 6 месяцев назад

❤❤

@lvjungle2840 2 месяца назад

I’m amaze how dentist learn this

@dr.battulapradeep1183 4 года назад

Sir.. Please do a video on anticancer drugs..

@maraolnagoo6153 4 года назад

its no a sir its a pharmacict u bullshit

@OnYoutubeInATutu 4 года назад

I take blackseed oil, lemons, green tea, turmeric, hemp, ginger, tomatoes, flaxseeds, garlic, graviola.... Works instead of tablet

@farahnaz5274 4 года назад

Sir can u plz make a video on anti viral and anti cancer drugs

@alhaithamalfarsi8167 Год назад

we want a video on Psoriasis treatments

@pavanivommi7317 4 года назад

Please do a video on antivirals

@sinaafrasyaw4975 4 года назад

دەستان خۆش

@KimNguyen-gz2nx 4 года назад

❤️❤️❤️

@abc_cba Год назад

Can you differentiate the difference between RAR and RCX receptors in skin ?

@JavidhMeeran 4 года назад

Do more videos often

@jonydepp9484 3 года назад

Sir can please explain about organo phosphate poisoning mechanism and oxime reuptake mechanism

@tvo3205 4 года назад

can we get Asthma & COPD meds

@AgentOffice 3 года назад

Smart

@Hormuud21 4 года назад

Can any one tell me the animation sir is using please

@HE-cm8kt 4 года назад

OMG I need this !

@kha0s616 4 года назад

Would you make a video on how isotretinoin is different from tretinoin?

@missgracyy22 4 года назад

Khalled Alves Isotretinion is taken orally and used to severe acne. Tretinoin is taken topically and use for mild to moderate acne.

@pharmaCON169 Год назад

Do you have lectures pdf for this??

@ramandeepsingh6607 Год назад

What’s the hormonal therapy for men ?

@jadeloren1 4 года назад

This is so good and informative. Great video, clear and aesthetically pleasing lol.. I wanted to know what I was putting on my face. I’m confident benzoyl peroxide/ doxycycline combo + tarazotene the dr prescribed along with healthy lifestyle changes for hormonal regulation (and prayer lol) will cure my acne! 🙏🏾

@danielg.3427 4 года назад

Great video, like always, however could do without the sound effects.

@aaliya.s2254 2 года назад

I stopped using adapalene and my acne came back. What can I do now till I take my next dermatologist appointment ? Is there a way to stop them for a few days? Im not able to plan my dermat appointment because of busy schedule and cant risk having acne back coz I'll be having events next week.

@sophie_1999_ 2 года назад

I'm confused! When converted into retionic acid, what does it bind to?

@Pathologyformedicalstudents 2 года назад

In the cells, retinoic acid enters the nucleus where it binds to heterodimers formed by two different classes of nuclear receptors: Retinoic acid receptors (RARs) and retinoid X receptor (RXRs).

@putrisusanti3937 Год назад

I use clindamycine gel for acne. And make a pih left? Why?

@gabriellanoelle1606 3 года назад

Can someone please help me with this question : Is the hormonal therapy part of this video only for females? Can males use spironolactone? Please let me know thank you so much. :)

@shinkiro4728 4 года назад

Please make one for DMARDS

@bestpenisenhancementat4pen594 3 года назад

I would recommend this acne guide *AcneCureOnline. Com* to anyone who is suffering from discovering the right acne remedies on their own. Our family is suffering from acne since then and I have tried different acne treatments. Luckily, with the help of this impressive guide, acne was cured and development was halted. .

@hamzakaya5230 4 года назад

Türkçe altyazı ekleyin lütfen 🙏🏻

@medicos8904 4 года назад

Pls uploads gi drugs

@Zhizhuzye 3 года назад

I really dont know what happen to me, I've acne since 14 yo but now suddenly it's getting worse, I even have acne in my head like in my scalp. I'm 20 yo now, and I dont know the caused of it 😭

@He_says_to Год назад

Most awkward feeling when some people look at you and say what is this or go to doctor They don't understand

@16Meily 4 года назад

These drugs are like a miracle yet SO expensive

@xDomglmao 3 года назад

Really? How much do you pay (and where are you from)?

@mmtv7418 2 года назад

Why i used tretinoin for 1 week but my acne become acne scars even if i didnt touch my acne

@ibibercerita 3 года назад

Excuse me Sir, I want to ask for my research paper. So when we give antibiotics, what happens to the bacteria? Are they totally killed or reduced or deactivated or what? Because as I know, P. acnes are naturally exist in every human skins. Thank you

@SpeedPharmacology 3 года назад

P. acnes is part of our skin's natural microbiome. Some but not all strains of the bacteria promote acne-causing inflammation. P. acnes colonizes primarily sebaceous glands and hair follicles but it may also be found in the mouth, nares, genitourinary tract, and large intestine. It is able to recolonize quickly after a round of antibiotics.

@ibibercerita 3 года назад

@@SpeedPharmacology but, it doesn't mean that the P. acnes will completely go away, right? They're become benign, aren't? Correct me if I'm wrong

@SpeedPharmacology 3 года назад

@@ibibercerita antibiotics commonly used in treatment of acne such as tetracycylines are inhibitors of growth (bacteriostatic) rather than killers of the bacteria. see my video about the pharmacology of antibiotics for more detailed explanation