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Protein-Ligand Docking with Autodock, follow the tutorial and perform docking with 100% confidence 

Muzzammel Rehman
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The molecular docking approach can be used to investigate interaction between a small molecule and a protein. Molecular docking is one of the most frequently used methods in structure-based drug design, due to its ability to predict the binding-conformation of small molecule ligands to the appropriate target binding site. Characterization of the binding behaviour plays an important role in rational design of drugs as well as to elucidate fundamental biochemical processes.
This video will provide you full step by step manual on Protein-ligand docking using Autodock
MGL Tools: mgltools.scripp...
Autogrid4 and Autdock4 : autodock.scripp...
Open Babel GUI: github.com/ope...

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12 сен 2024

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Комментарии : 27   
@DarkSide-mk2ij
@DarkSide-mk2ij 2 года назад
congratulation Sir for 1k views.. Allah or be kamiyab kry apko..Ameen.. Lots of love from ur student..
@MuzzammelRehman
@MuzzammelRehman 2 года назад
Thank you
@MuzzammelRehman
@MuzzammelRehman 2 года назад
Who are you by the way ??
@MuzzammelRehman
@MuzzammelRehman 2 года назад
Muzzammel.phd.ibb@pu.edu.pk Send me an email
@ProfessorRehmanShahzad
@ProfessorRehmanShahzad 2 года назад
Exvellent job Hafiz Sahb
@sushiladevkota2693
@sushiladevkota2693 2 года назад
God bless you sir
@MuzzammelRehman
@MuzzammelRehman 2 года назад
Thank you
@Rekhabohra19
@Rekhabohra19 2 года назад
Nicely explained.. thank you so much
@MuzzammelRehman
@MuzzammelRehman 2 года назад
Thank you
@abidatahseenakhtar2339
@abidatahseenakhtar2339 2 года назад
Excellent
@lola-mn2kw
@lola-mn2kw 2 года назад
you safe my life. thank you very much
@amrindersingh4751
@amrindersingh4751 2 года назад
Can you please do molecular dynamics using gromacs
@MuzzammelRehman
@MuzzammelRehman 2 года назад
Yes , very soon . Stay tune and share with others to promote free education
@amrindersingh4751
@amrindersingh4751 2 года назад
Thanks. Sure
@fairyvlog9509
@fairyvlog9509 2 года назад
Very informative.. kindly upload a video for docking of urease enzyme using moe software
@MuzzammelRehman
@MuzzammelRehman 2 года назад
Thank you
@manojdhameja4212
@manojdhameja4212 2 года назад
Sir, i had performed molecular docking of a standard inhibitor against a target enzyme. Both Vina and Autodock were used (active site docking). Vina results are good and are same as present in literature, but Autodock results are very different with wrong binding affinity. Why is it so ? With vina, inhibitor is binding to active site however with Autodock inhibitor is not binding to active site and goes to anywhere else. What to do now ?
@nhungdaothi719
@nhungdaothi719 4 месяца назад
Thank you so much. Can I dock if my ligand is outside protein?
@MuhammadFaizan-mi9yo
@MuhammadFaizan-mi9yo 2 года назад
can you post the PPTX of the lectures here.
@cappamaampi2452
@cappamaampi2452 2 года назад
Think you very much
@MuzzammelRehman
@MuzzammelRehman 2 года назад
you are Wellcome
@hamzasohail3110
@hamzasohail3110 2 года назад
very nice dr muzammil, i am beginner to protein docking, i have one question. If we have some proteins with 2 or 3 chains? then how we will decide that which chain we have to select for docking? is there any criteria or tool?
@MuzzammelRehman
@MuzzammelRehman 2 года назад
Find out the binding site by literature if it is trimer of same chains and binding site is not present at the junction of two chains then you can use anyone of the chain. And if it is on the junction then you should choose both of those chain
@UrduInformationWorld
@UrduInformationWorld 2 года назад
❤️👍💯
@AmiNa-es1vc
@AmiNa-es1vc 2 года назад
Open babel's link dont work
@jllai7453
@jllai7453 2 года назад
the autodock4 can't be downloaded. how can I install?
@MuzzammelRehman
@MuzzammelRehman 2 года назад
You can try from this page autodock.scripps.edu/download-autodock4/
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