Autophagy, a vital cellular process meaning "self-eating," plays a crucial role in cleaning out damaged cells and regenerating healthier ones, promoting longevity and disease prevention. This process can be initiated through various methods such as fasting, which reduces insulin levels and increases glucagon, activating key regulators AMPK and inhibiting mTOR. Exercise, particularly high-intensity interval training and endurance workouts, also stimulates autophagy by depleting cellular energy stores. Certain dietary components like the ketogenic diet and nutrients such as resveratrol, curcumin, and green tea catechins can promote autophagy. Additionally, pharmacological agents like rapamycin and metformin, as well as natural methods like heat and cold exposure, can enhance this process. Supplements like nicotinamide riboside and berberine further support autophagy, contributing to overall cellular health and longevity. By incorporating these strategies, individuals can effectively harness the benefits of autophagy to improve their health.
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17 июн 2024
