Retrotransposons | Retroviral retro transposon | Non LTR retrotransposon | LINEs and SINEs | molbio 

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Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

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LTR retrotransposons do not require a transposase enzyme for their transposition. Instead, they rely on their own encoded enzymes, namely reverse transcriptase and integrase, to carry out the transposition process. Reverse transcriptase is responsible for the conversion of the RNA transcript of the retrotransposon into DNA. It synthesizes a complementary DNA copy (cDNA) based on the RNA template. This cDNA is then integrated back into the genome by the action of integrase. Integrase is the enzyme that facilitates the integration of the cDNA into the host genome. It recognizes specific DNA sequences and catalyzes the cleavage of the target DNA, allowing the retrotransposon cDNA to be inserted at that site. The integration process is usually precise, occurring at specific target sites, although occasional errors or off-target integrations can occur. Transposases, on the other hand, are enzymes that are involved in the transposition of other types of transposable elements called DNA transposons. DNA transposons move by a "cut and paste" mechanism that involves the action of transposases to excise the transposon from one genomic location and insert it into another. In summary, while transposases are required for DNA transposons, LTR retrotransposons use their own enzymes, reverse transcriptase and integrase, to accomplish their transposition.