Reversing the biological age of skin: the science behind why/how it's possible | OneSkin Interview

PENN.SMITH.SKINCARE

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0:00 Introduction
2:47 How DId the 4 of you come to meet and start OneSkin?
6:22 What is senescence?
8:17 What is the difference between OneSkin and supplements that help with cellular senescence?
9:49 What is the human skin equivalent? How does it relate to human skin?
11:30 What is the Molclock?
14:30 Where are you with the studies on OneSkin and its effect on systemic inflammation in the body?
17:31 How does the OS-1 Peptide in OneSkin penetrate the skin when it doesn't follow the "500 Dalton rule"?
20:24 Why did you decide to make OneSkin in the form of a lotion?
21:54 Can you explain the Hyaluronic Acids in your formula?
Can you explain the relationship between OneSkin and menopause? How does it effect inflammation and how may it be beneficial to someone who is menopausal?
24:47 Can You Explain between OneSkin and menopause?
27:34Can OneSkin address hyperpigmentation? Are there any indications that it can help with melasma?
30:43 Can you address how OneSkin should be layered in a skincare routine?
32:35 Why is the OS-1 Peptide the last ingredient on the list?
33:45 How long does it take to see results form using OneSkin?
36:00 What is the difference between OneSkin and DNA repair products?
37:11 Can you explain the relationship between mitigating senescence and cancer?
41:45 Can you share if there are any more OneSkin products coming out in the future?
43:54 Can you elaborate on OneSkin body and how it can be beneficial to use over the summer?
44:30 When will OneSkin be available for shipping outside of the US?
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Disclaimer: This video is not intended to provide diagnosis, treatment or medical advice. Content provided on this RU-vid channel is for informational and entertainment purposes only. Please consult with a physician or other healthcare professional regarding any medical or skin related diagnosis or treatment options. Information on this RU-vid channel should not be considered as a substitute for advice from a healthcare/skin professional. The statements made about specific products throughout this video are not to diagnose, treat, cure or prevent disease. It is important that you check labels to determine if a product is right for you. Before starting any treatment at home consult a health care or skin care professional to determine if it’s right for you.

Опубликовано:

24 июл 2024

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Комментарии : 248

@courtneyjackson4843 2 года назад

Everyone who has been taking care of their skin for awhile (decades for me) should know it absolutely takes 12 weeks. I wasn’t seeing much because I was doing basic things already but at 3 months the change was noticeable - remarkable- so give it time.

@PENNSMITHSKINCARE 2 года назад

Such great advice 💜

@Luv4taffy1 Год назад

Does the coupon code work for the subscription ?

@toni3558 Год назад

@@Luv4taffy1 Yes, I just used the code and it worked.

@cjroelof 2 года назад

Thank you so much Penny for putting this video out . So many of my questions that I had were answered. cant wait for the next products to come out!

@susanyates3926 2 года назад

Amazing!! Thank you so much for this interview. I hope you are able to periodically keep us updated on Oneskin and what’s new with their company and research. Amazing women!!

@PENNSMITHSKINCARE 2 года назад

Yes! I will for sure, I am really excited to see what they have coming out in the future! 💕

@lj6266 2 года назад

Was looking forward to this and it didn't disappoint. Very well articulated for the layperson. Thank you penny, as always a great and informative video xx

@PENNSMITHSKINCARE 2 года назад

Thank you so much! This was a challenge for me bc there was almost 2 hours of conversation….and hard to cut anything these amazing ladies had to say! Thank you for being here ❤️

@dj4512 2 года назад

Thank you! I have been curious about this product and have been waiting for you to talk about it again.

@Sera-R 2 года назад

Penn this is such an informative and amazing video! Thank you for this detailed interview. This was so helpful in making my decision to purchase.

@kimdorcy5150 2 года назад

I love how you show us the brains behind this new technology. I trust the information you provide and this type of video helps me to have more confidence . Thank you so much. Im a science need too!

@PENNSMITHSKINCARE 2 года назад

I’m so glad you enjoyed it Kim. I am fascinated by skincare science and I love (love!) speaking with genius women. It’s inspiring to me, and I hope it inspires other women too! 💜

@playsintraffic2 2 года назад

I’ve just finished my first bottle of the body supplement. It has drastically improved the sun damage I’ve gotten on my arms from decades of commuting and not wearing spf on my arms. Plus an improvement in texture. I really wish I’d taken before and after pictures

@PENNSMITHSKINCARE 2 года назад

This is incredible to hear! Thank you for sharing 😄💜

@kerryallen4665 2 года назад

Do you mean the lotion for the body or am internal supplement? My arms and legs have so many spots from sun damage. It’s so expensive I just don’t know what to do.

@shelleyadamschristian6345 2 года назад

@Lala-wc4wt 2 года назад

@@shelleyadamschristian6345 9

@shellierichards7128 Год назад

SAME! ME TOO!

@r2_rho Год назад

This was an incredible interview, thank you for putting this together!

@tzoe875 Год назад

I cannot believe that I waited this long to watch this video! I am so excited and encouraged by this product! It is thrilling to hear such well informed , educated, brilliant female scientists. Every young STEM student should watch this video and learn about the science and products. This makes science and lab driven research exciting. I am interested to know if they are researching diabetic skin and other autoimmune diseases as they are full of inflammatory markers. Penn, I want to give you a very sincere thank you for digging deep and promoting amazing science. 👏👏👏

@shelleyhuskey1216 Год назад

Loved to see this video! Can't wait for this product to arrive! Thank you for all the product reviews here in the comments as well!!!!

@LenaSheppard 2 года назад

So, so fascinating! Thanks for sharing this meeting with us. I so appreciate you being here !

@PENNSMITHSKINCARE 2 года назад

Thank you Lena! 💜

@AgingNaturallywithJodylynn 2 года назад

Well this was amazing! Loved your questions! This was wonderful Penny! I love these ladies and what they are doing. Very creative and innovative product! I can't wait to get mine. ☺️🙏♥️

@msmarooshka 2 года назад

I've been using this for about a month now and am loving it, it's almost like a serum becuase it absorbs quickly! I have the body lotion as well. Loved watching this, thank you! 😘

@jojolina71 2 года назад

No one should miss out on this sublime video! More than worthwile listening to!

@kellyc3897 2 года назад

Thank you for this in-depth interview Penny 🙏🏽 🙌🏾 I'm on my second bottle of One Skin!

@PENNSMITHSKINCARE 2 года назад

Thank you for being here Kelly! 💜

@skincarelover9568 2 года назад

Wow Penny !! Fascinating thank you!!! You are rocking it girl!!

@PENNSMITHSKINCARE 2 года назад

Oh my gosh thank you!

@Criticalbeauty411 2 года назад

Your questions are incredible thank you so much! I think the biggest thing holding me back is simply lack of room in my current routine. I am trying to give most things at least three months to sort of earn their place in my permanent routine but I have been looking at this and will likely try it next. I guess it’s just difficult even rotating things in “first position” because I really wanna put my money behind the ingredients with the most research. If it comes difficult to discern newer research versus marketing. It’s still a bit of a process but this video is incredibly helpful so thank you so much!

@PENNSMITHSKINCARE 2 года назад

I understand this completely. If I didn’t review and test skincare for this channel I would likely also pair down my routine. It’s interesting, on one hand I feel like it’s amazing that we have so much innovation and choice and on the other hand it’s overwhelming and hard to choose/where to put something etc. So I completely get it!!

@mimimoon6082 2 года назад

I've been patiently waiting for this video!!! ❤️😘

@tammyb.1375 2 года назад

Me too!! :)

@PENNSMITHSKINCARE 2 года назад

Thank you for being here ladies! I appreciate you both! 💜

@allymacredie1043 2 года назад

Excellent interview! Thanks everyone!🦋

@PENNSMITHSKINCARE 2 года назад

Thank you for your kind comment 💜

@lisahart1267 2 года назад

I just got mine last week! Can’t wait for this video!!!!

@nicci2534 Год назад

How is the product working for you? Any results? Any adverse reactions?

@anirudhnair9588 8 месяцев назад

Great interview and really provides an insight into skin care and aging knowledge ❤

@annaibbo65 2 года назад

Fascinating and riveting can't wait till we can get it in the UK thank you for showcasing these products they sound amazing and what wonderful inspiring women you and they are xxx❤️❤️❤️❤️

@beyond50skin 2 года назад

Super interesting! May I ask if any of the lab studies are published? I’d love to read. Thanks for sharing One Skin’s brand story with us & the lovely women behind the brand.

@PENNSMITHSKINCARE 2 года назад

I’ll get details for you 😄 I do know that they have one large study (large to me-I think 60 participants) going now that is double blind, placebo etc etc etc that will be done by the end of the year. I’ll work on details!

@beyond50skin 2 года назад

@@PENNSMITHSKINCARE Thanks, appreciate it.

@maysamabeauty1839 2 года назад

Gosh, I so enjoyed this vid Penn. Such wonderful talented women and the science behind the brand is incredible 🙌🙌💚

@PENNSMITHSKINCARE 2 года назад

I totally agree!

@RBarCar 2 года назад

That was incredible. Thank you so much for sharing. 👏👏👏

@PENNSMITHSKINCARE 2 года назад

Thank you Rosalie! 💜

@pamorama 2 года назад

I can’t believe that these beautiful, young, intelligent women are doing such amazing, high-level scientific work. I’ve only made it about a third of the way through but I’m really mesmerized by this. Thank you so much for connecting with these women and explaining the science of one skin to us!!!

@dionline88 2 года назад

This was a wonderful interview! Such intelligent and passionate scientists who understand what we women are looking for. I'm super interested and will be looking at your comments - and thank you for the 20% off code in your description section. That will come in very handy!!!

@michellejubinal9043 2 года назад

So much wealth of information. This is a video everyone needs to see.

@PENNSMITHSKINCARE 2 года назад

💜💜!

@ravenspadegirl 2 года назад

OK..I just placed my order thank you for another wonderful video

@shellierichards7128 Год назад

I began using One Skin on my body and after about 3 months, I noticed I could no longer FEEL my stretch marks (I had a lot). My skin felt nearly smooth--I could still SEE the stretchmarks, but they were considerably diminished. I believe this product works. I wish I'd taken before and afters!!!

@PENNSMITHSKINCARE Год назад

So great to hear about other peoples results, thank you so much for sharing!

@lisamartin8011 2 года назад

Yay!!! I've been waiting for this video Penny! I bought this on your recommendation and I am loving the results 🥰 I have it on on auto delivery 😁👍

@PENNSMITHSKINCARE 2 года назад

I am so happy to hear that you love it too!!

@lisamartin8011 2 года назад

@@PENNSMITHSKINCARE ❤️🥰

@eyllisamarieskinsilva8703 Год назад

This is the skin science i need more of !🎉

@MaxineV 2 года назад

Great interview, thank you all. :)

@PENNSMITHSKINCARE 2 года назад

Thank you for being here ❤️❤️

@flowerchild2409 2 года назад

Well this was very helpful, I have been on the fence about this peptide, like just not really grasping how it could be beneficial for me but this really explains a lot for me. I'm placing the face and body product on auto ship, I'll find a way to work it in, the peptide is going to work from a different angle from the other actives, they are all providing benefit from different approaches. I am excited to get started on this peptide and see what I can appreciate in the next 3 months or so! Thank you Penny!!!!!

@PENNSMITHSKINCARE 2 года назад

I hope you love it. I understand trying to fit something in. There are things on the market now that I want to try but can’t think of how I’d really fit them in. I can’t wait to hear your review in 3 months 🙃❤️❤️

@nicci2534 Год назад

How has the product been working for you now? Do you see results? If so may ask which ones? Any adverse effects? Thanks🙂

@iriskaufman5048 2 года назад

Thank you for this interview, so informative. I’m on my third bottle of face, and 2nd for the body. Starting to notice some real changes in my face. I did notice improved smoothness and softness after first bottle, but now I’m starting to see overall brightness and improved firmness and texture. Hoping to improve the creepiness of the skin on my arms, I do notice that the skin is softer after the first bottle, excited to see the improvement that can be realized after three bottles.

@PENNSMITHSKINCARE 2 года назад

Thank you so much for sharing your results!

@ldelre7439 Год назад

How do you use in your routine? Do you put this on first prior to vitamin c (in morning) and tret (in evening)?

@JW99736 2 года назад

I would love to see exactly how much inflammation was decreased in the blood tests of the participants the 5 person topical study. Hope you can have them back once it’s published to go over the results. Super exciting concept, not only for skin but for internal health as well!

@pepperweinglass Год назад

I have been using oneskin for 1 month, I noticed first on my body how smooth my arms were, bumps were so much less. And on my face smoother skin, good to know about the layering. I will change to use one skin first now! Thank you for so much information!

@flickerina7 Год назад

I purchased it and the product has delivered! My skin is firmer and plumper. Thanks for doing the research.

@PENNSMITHSKINCARE Год назад

So happy to hear this!

@PhenixJoe 2 года назад

I have been using it for about three months now and I absolutely do notice a difference. My skin just feels most substantive and smooth. It’s not a “quick fix” product; you have to give it time. I purchase the face and body supplement. My only complaint is that I do have a hard time getting either product to last me the full month. I like to use the face supplement on my face, neck, and chest so normally I’ll add a squirt of the body supplement to 2-3 squirts of the face supplement so that it covers all of those areas - that’s my little “tip”. Just wish they each contained a BIT more product.

@iriskaufman5048 2 года назад

Me too ! I’ve been using the body lotion on certain areas of concern and it lasts me about one month. I think it would take at least two bottles to use on my entire body for one month. If I had that kind of budget I certainly would be using it all over!

@PhenixJoe 2 года назад

Yeah same boat! It’s definitely not intended to be for the entire body but rather more of a targeted treatment for problem areas on the body. I don’t even put it everywhere and I don’t think I’m using an exorbitant amount but I always run out like 18 to 20 days into the month. I also run out of the face lotion early but not quite as early as with the body.

@barbiekat6352 Год назад

How much is a “squirt”? Is it one pump? 🤷🏻‍♀️

@MarionMM 2 года назад

This was such a nice interview and answered a lot of questions I had. I can't wait for them to ship to Europe, but I will likely just have it delivered to someone who will ship it to me for now. 😉

@PENNSMITHSKINCARE 2 года назад

I can’t wait for them to ship overseas as well! Thank you for your kindness ❤️

@czariva8094 2 года назад

Dear Penn! Thanks to ask them about export one skin, I am from Brazil and I would like a lot to try this peptide. Always I watch your videos, I admire you!!💝💝💝

@PENNSMITHSKINCARE 2 года назад

I am so happy you’re here!! These Brazilian women are so incredible! Happy Sunday ❤️💜☀️

@melindacsk2112 2 года назад

I’m on my second bottle because of you Penny! xx

@PENNSMITHSKINCARE 2 года назад

I hope you are loving it 💜

@ldelre7439 Год назад

Do you still like it?

@carrieg8779 2 года назад

I enjoy your wonderfully informative posts and have incorporated many of your suggestions. Thank you❤️ Question: your blouse is adorable! Would you be okay to share where got it?

@PENNSMITHSKINCARE 2 года назад

Thank you!! I’ll try and find this blouse 💜

@michy2630 2 года назад

I do not use these products but so interesting listening to these smart, talented women. Terrific questions Penny

@PENNSMITHSKINCARE 2 года назад

I am SO glad! My intention is to share science and innovation for everyone regardless of whether or not they’d use a product. I love to read/hear about things that I never plan to buy as well. It’s all just interesting to me. I’m glad you share that perspective 💜

@michy2630 2 года назад

@@PENNSMITHSKINCARE I do not feel you have to use a product to listen to videos, podcasts, etc. I love learning about skincare and you work so hard finding various products, technologies, teaching the science, etc. I have tried so many of the products you suggested. Some work and some have not but I appreciate the content here and just learning along with you.

@PENNSMITHSKINCARE 2 года назад

🙏💜💜

@asphaltsally 2 года назад

Thank you so much for this! I bought One Skin immediately after seeing your first video about it and I do love it and have it on autoship, but I can never give up my copper peptides and tretinoin so I have been concerned about how to use them all. Can't wait for the eye product! The OS1 face burns my eyes a couple of hours after application if I get it too close to my eyes.

@PENNSMITHSKINCARE 2 года назад

Ahhh I’m sorry it’s bothers your eyes! That’s a bummer. Hopefully the eye product will be better for you 🙏❤️

@karlaharvey2623 2 года назад

Thank you for sharing that it burns your eyes if too close to them. I am waiting for my 1st shipment. I have very sensitive eyes, so will for sure be very careful of not getting it too close.

@ldelre7439 Год назад

May I ask what copper peptides you love?

@SlMONSAYS 10 месяцев назад

Just ordered the OneSkin eye & face using PENN15 - worked like a charm! 🙂 - Brandon (from VA)

@christineganeaux8666 2 года назад

I have a question that I have been researching for an answer to regarding the use of Oneskin in conjunction with an EGF (in my case Bioeffect). Is that counterintuitive, or even potentially detrimental? I emailed Oneskin customer service, but didn't quite get an answer. If you happen to know it, or speak with the team at Oneskin again, I would love to know your thoughts. I watch your videos regularly, and read your blog. I appreciate so much what you offer to your followers. Brava!

@jacquelynwathen8676 2 года назад

So very interesting. Brilliant women. Thanks for doing this

@PENNSMITHSKINCARE 2 года назад

Thank you for your kind words! Happy Sunday, I appreciate you! 💜

@ellenmuthexperiments2254 2 года назад

Fascinating! Great follow up to your first OS video. Sorry if this is slightly off topic but you mentioned oral supplements that help with senescence, do you take any that are helpful and, if so, might you share a brand name that is worthwhile?

@PENNSMITHSKINCARE 2 года назад

I take Fisetin with quercetin by a brand called Sharoaid. I’m sure I originally got that brand watching someone else (lol). It is a liposomal supplement (which is my preferred type of delivery). They are soft gels that you take daily. Hope that helps 💜

@cformosa Год назад

I would love to know how One Skin products might work with the DNA Repair Enzymes that Penny has made videos about… since I’ve had basil cell carcinomas removed in the past (I was a lifeguard and mermaid, grew up on a lake), I am extremely interested in the DNA REs.

@keithrichard391 Год назад

I started taken alot of HA from Do Notage and my skin is much much younger looking!!!

@Lulu-kt6gr 2 года назад

How does this mesh well with retinoids ? Retinoids thin the epidermidis while they thicken the dermis but if this product thickens the epidermis, do you need to stop using retinoids?

@beckyc.5743 2 года назад

Thanks for asking questions about the HA and molecular weight of the products. I was fascinated by the information on hyperpigmentation as well. After hearing everything these scientists had to say there’s no good reason for me NOT to use this product.

@PENNSMITHSKINCARE 2 года назад

It was such a fascinating conversation Becky! I could talk to them for hours. I’m glad you enjoyed it 💜

@CH-fk9rw 2 года назад

Great video. Would this replace the need for a pigment inhibitor?

@lornaoyarce1355 2 года назад

I love you PENN. I love One Skin. I would likely buy anything that you give this much attention to. I need to know now how to incorporate retinol, vitamin C, Co-Q, Ultimate Serum, Photozyme, Emepelle and Defenage. AND, I must know where you found that adorable blouse.

@PENNSMITHSKINCARE 2 года назад

First, thank you for being so very nice. It means a lot to me. So I use almost all of that myself-here’s how I do it. At night is my retinoids, OneSkin, Revivserum and photozyme. I rotate Revivserum, photozyme and OneSkin in first position (but often it’s reviv then photozyme then OneSkin just based on their consistency). I now use Q10 (just added it to my AM routine) and already vitamin C, astaxanthin (among other things). I rotate those things as well (I do not use them all every day. My skin doesn’t like it lol). So that’s the split. If I still used emepelle cream it would be at night and it would be considered my retinoid. I am using a retinoid every 3rd night right now but may go back to every other night in the fall. I’ll admit, it’s like a huge puzzle and I’m not perfect. I just try to listen to my skin and do my best. It’s hard when there are SO many great things to use-I know that sometimes I actually just need to put one down (emepelle for me) because I just can’t do it all. I hope this insight helps in SOME way 🥰

@PENNSMITHSKINCARE 2 года назад

Another piece of insight that helps me- I look at my skin like my diet or my supplements. Rather than day to day, look at it week to week or even sometimes month to month. Balance what you want to “feed” your skin by the week and it’s much easier to get it all in. Food for thought (no pun intended 😉)

@sylviazysko6968 2 года назад

looking forward when that starts shipping to France or United Kingdom, would love to try

@debijo5288 2 года назад

I have it, been using it morning and bedtime; it really sinks in fast. It also feels good on.

@PENNSMITHSKINCARE 2 года назад

I’m so glad you like it Debi 💜

@user-bq6yg3gv9p 2 года назад

Penn, thank you so much for this video. My take away, in a nutshell, is that this product can be used in lieu of Emepelle (which I was just about to invest in) and repair enzymes as it will address both of those concerns. Is that a correct conclusion?

@megand5672 2 года назад

Thank you curious about retinA and dna repair which I think you no longer need with this product?

@PENNSMITHSKINCARE 2 года назад

Personally I think this compliments vitamin A and also DNA repair enzymes. The repair works in different ways (dna repair enzymes and OneSkin) and tret encourages cellular turn over (which the other 2 do not). Emepelle is different as well with MEP technology-mimicking estrogen. That said, personally I would choose this over emepelle (after using both. I think emepelle is a very nice product but I like OneSkin better myself). I hope that helps ❤️

@Angela-sm5fj 2 года назад

Hello Penn, I'm just now watching beginning of this video. Do the doctors say where they source human skin from? Is the skin replicated in petri dish?They talk about looking at layers of skin and looking for peptides within, but I am curious about original skin donor

@PENNSMITHSKINCARE 2 года назад

Hmm. I’ll ask. I know that they “grew” the skin. I’ll ask for the source!

@lisamartin8011 2 года назад

Thank you for the explanation! When I try to explain to my hubby why I need One skin on Auto ship.,..."watch video.....there ya go!"👍😁❤️🤣

@PENNSMITHSKINCARE 2 года назад

😂😂

@lisamartin8011 2 года назад

@@PENNSMITHSKINCARE 🤣🤣🤣

@machellemcneill5743 2 года назад

Thank you so much for these comparisons. I have also watched your video on One Skin too. I have a question though? Do you use One Skin and the SkinMedica TNS Essential Facial Serum + Osmosis MD Remedy+ Epicuren ORAC Age-Protect Serum OR could you narrow it down to just One Skin?

@Estefaniapmr 2 года назад

Following

@lakeside23 2 года назад

Fantastic! I've sent this to so many friends. Do you think OS-01 is too thick to use with derma rolling? I've been applying it afterwards. What are your thoughts now that we have DNA repair products to consider. Thanks!

@PENNSMITHSKINCARE 2 года назад

Actually….I am planning to dermaroll and apply OneSkin after! Yes!!!

@Anonymous-sh9vk 2 года назад

I have been using OneSkin for about a month after I saw your video on it, and I like it! It's early days for judging results though. I actually just watched yesterday's video with the new Exponent products and I had a question in the comments that I hope you won't mind if I add it here too: I checked out the Hydrator ingredients, the 4th in the list is a dimethicone, and in the powder ingredients two of the top three are also. I know that they are supposed to provide some sort of barrier to "lock in" moisture, etc., but doesn't that work both ways? Won't using a product with a lot of dimethicone early in your routine also prevent absorption of products layered on top of it? I hope you know more about this than I do - I can't seem to find any information about layering on top of dimethicone-heavy ingredients. :)

@PENNSMITHSKINCARE 2 года назад

I am going to ask someone smarter than me about the occlusive nature of dimethicone. I know (obviously) that silicones CAN be occlusives but I assume that there are ways to formulate silicones so that they are more or less occlusive. I agree, it’s important regarding the exponent-I’m using it first so obviously I do not want it blocking other things out. I’ll do my best to get some answers and be back! 💜

@Anonymous-sh9vk 2 года назад

@@PENNSMITHSKINCARE Thanks so much! I have tried looking around online but I just can't find anything on it. Maybe it's an industry secret they don't want us to catch on to? j/k :)

@serenajarvis3548 Год назад

Aloha Penn, just wondering isn’t Tetrapeptide-53 used for hair growth? Cannot find information listed for anti aging in skincare?

@AnnSwansonWellness 2 года назад

This is phenomenal! How do you incorporate your Oneskin with photozyme dna repair and vit c serum? Oneskin suggests to put their product first but I find myself wanting to put the serums first. What order do you do them or do you switch each day which products you use?

@PENNSMITHSKINCARE 2 года назад

I pretty much still do thinnest to thickest (so OneSkin isn’t usually first). Although I have been known to mix photozyme and OneSkin and apply together 1st. I think that helps my brain with choosing 😂

@AnnSwansonWellness 2 года назад

@@PENNSMITHSKINCARE It is hard to choose! Thanks so much for your answer

@wendycarlton919 Год назад

How do you use with retinaldyhide? Additionally and more specifically how do you layer this since its a cream and you traditionally layer thinner serums first then cream would you still use your normal serums and layer this on after or would it just take longer to see results from OS if you do it that way since not applying directly to clean skin? This is what i would love clarification on. Do i have to forgo my other serums and just use OS? Thank you in advance for any feedback on this topic!!

@melissastewart1315 Год назад

So would this product be considered a “DNA” repair serum or Growth serum ? I was thinking of buying the photozyme DNA repair or TNS growth serum but don’t want to duplicate

@debijo5288 2 года назад

I ordered my second face lotion with the 20% off.

@BeachieDogMom 2 года назад

Would you use one skin in conjunction with microneedling? Or apply it right after microneedling?

@brendawatring602 2 года назад

Thank you

@Lulu-kt6gr 2 года назад

I suppose you could use this at night only and serums etc during the day?

@nikkishevillo8741 2 года назад

Hi!! Great video!! I’m on my second body bottle so I’m hoping to c a different soon:) I do feel like my skin is less creepy. My question is I love Neogenis Recovery for face, should I use the face serum this brand and Neogenis? Thx! 😍🥰

@iriskaufman5048 2 года назад

I use neo Genesis recovery, and it’s a very thin almost watery product which disappears almost immediately with no tackiness. It’s almost as if nothing is there, so I think OneSkin would penetrate after using recovery.

@nikkishevillo8741 2 года назад

@@iriskaufman5048 thx!!!

@nikkishevillo8741 2 года назад

@@iriskaufman5048 thx!!!

@trinadimico4494 2 года назад

Penn, I would love to be a Participant! Any idea how I can contact them to be considered?? Thank You! 🙏

@lynnkristy1 2 года назад

Next question to be asked. I can’t use niacinamide ( makes me itch) how much is in this product? 1/2 or 1/3 or 1/4. Would love to use but concerned I can’t due to this issue loved the info. Hoping can use. Thx for doing. 💕

@PENNSMITHSKINCARE 2 года назад

I’ll ask for sure! I do agree, niacinamide is in everything….it makes it challenging for people with sensitivity to it 😐

@karenhinkle7992 2 года назад

I’m 79 and have a few dry spots on my skin...can this help them? Also I’ve been using this for a few months and have seen no difference! Thanks 💜

@BoricuaGirl69 2 года назад

I just turned 66 this month. I’ve been using the face lotion for about 2 months. It’s like a nice moisturizer for me. No changes to my fine lines and wrinkles 😭😩

@Cindy-hz3kl 2 года назад

Thank you for this awesome video. Based on your initial video, I have been using both products for about a month. I do see changes in my skin. I have not been applying the face product first because I apply photozyme first and then my growth factors. If applied first, will it affect the penetration of the other products? It is always first on my legs and torso.

@mimimoon6082 2 года назад

Excellent question. I hope she answers. 🤩

@PENNSMITHSKINCARE 2 года назад

I use it in a rotation (order wise) with Photozyme and also sometimes Reviv. I have also mixed it with Photozyme… I will revisit the ingredients but I do not think it restricts penetration 💜

@Cindy-hz3kl 2 года назад

@@PENNSMITHSKINCARE Thank you. I may mix it with photozyme. I really love applying it twice a day especially since I just turned 63.

@jeremyross6331 2 года назад

I would really like to know if my serums, Retin A, Queen, can penetrate.. I am on my second bottle and can’t say I have noticed any improvement and I am worried now that I may have wasted two months of applications because I was applying this lotion as my last step. Perhaps too many layers to penetrate???

@Cindy-hz3kl 2 года назад

@@jeremyross6331 I was applying it in the same way. Now I am applying it first and mixing it with photozyme. I am thinking of applying my growth factor first and rotate. I do see changes but I know that it can take up to three months to see a difference especially at my age.

@marinahuq1577 2 года назад

Yes I was curious how it would penetrate also how can a piece of skin be compared to actual living skin ??

@wendycarlton919 2 года назад

One thing that stood out is that oral supplements don't have a big affect. I currently take high grade collagen, CoQ10, glutathione, etc. Should I continue to take if I were to try one skin? Seems it can't hurt but I find it hard to believe that they don't have an affect. I am also curious on the dimethicone question that was askedandlayering other products/serums. Thanks for I feedback and opinion!

@Estefaniapmr 2 года назад

What supplements are you taking? I’m looking for the best in the industry. :)

@wendycarlton919 Год назад

@@Estefaniapmr Hi, I take an assortment through Cymbiotika, check out their website for your concerns and what you are trying to target. Let me know what you think after you check it out.

@sonjaartisania Год назад

Thos supplements are really powerful immune and liver support nutrients. I would 100% continue to take them 👍🏼

@karishmah4033 2 года назад

Hi Penny! If I am 21 years old should I be using this product? What is the optimal age to get on this? Do Asians get on it later because their biological age is known to be slightly less than their chronological age? Also, how frequently should we be using this? Is there any chance at all that using this or using this inappropriately may cause our inflammatory response to reduce so much such that it is detrimental to our bodies? Thanks for answering all of my questions Penny:)

@PENNSMITHSKINCARE 2 года назад

I’ll pass along all of this! Thank you for such thoughtful questions! 💜

@laly6980 4 месяца назад

Great video! I saw Dave Asprey interviewing the CEO of this Company and I started researching in RU-vid and luckily found your video 😊 I am going to give it a try. Did you tried this product and what do you think about it?

@PENNSMITHSKINCARE 4 месяца назад

Yes! I have been using OneSkin for quite awhile and still love it.

@calexprenas Год назад

Penny, someone noted on another forum that they mention tetrapeptide-53 in the interview but that the listed peptide is decapeptide-52, and how very odd it is to not know the name of the prized peptide that they developed and is at the center of everything discussed. What are your thoughts on this?

@PENNSMITHSKINCARE Год назад

I’m sure it’s my mistake, not theirs 😊 I meant to follow up on that-I’ll ask!

@calexprenas Год назад

@@PENNSMITHSKINCARE Thank you for always being responsive to viewer concerns, Penny. 💗So appreciate your thoughts and commitment to transparency. Look forward to hearing about what you learn (really don’t think it could be anything you did btw!)

@vivixwaldo4227 Год назад

Does it sell in Europe? I can not find anyone that sends it to Germany

@debpalm8667 Год назад

The "skin" they use in the lab, does it have a barrier like our skin? If not, what does that mean for absorption? I will look for the update.

@barbiekat6352 Год назад

I would like to hear from OneSkin representatives regarding this issue: People are commenting that their bottle doesn’t even last one month. That is contradicted by the OneSkin website’s FAQ section where you can read the following: Q.How long will my Topical Supplement last? A. “We estimate the 50 ml bottle of OS-01 FACE will last approximately 1-3 months when used as directed. The 250 ml bottle of OS-01 BODY will last approximately 1-2 months, when used as directed.” If this is accurate, then that means the cost is less per month for those of us that are budgeting. Could some be using too much product or more than necessary for results? I get that how much of the body formula used can range greatly, depending on number areas it’s used on. But the face product use should be better able to estimate using on face once or twice daily.

@karlaharvey2623 2 года назад

Thank you for interviewing these ladies on their One Skin. I ordered my 1st bottle and it’s ready to ship. My question is when using Photozyme and Reviv: they need to be the 1st step in our skincare routine. So: which one do you recommend applying 1st in am and Pm? I guess I could apply One Skin 1st in am or Pm and the other 1st in the am or Pm where I applied the One Skin 1st and interchange them as my 1st step. Thank you Penny.

@PENNSMITHSKINCARE 2 года назад

I rotate it in to first position at night. They said that their research findings (results) is based on OneSkin being used first. However, I do not think that either the photozyme or reviv would inhibit penetration (just my opinion obviously😊)

@karlaharvey2623 2 года назад

@@PENNSMITHSKINCARE Thank You Penny. I spoke with Randy yesterday re: Photozyme. He mixes about half a pump with his Vit C serum in the am. As he said they do recommend to use as 1st step. Have you tried the Reviv Vit. C 36% serum? I’ve been using Timeless 20% for sev months and feel like I need to change it up for awhile. The Reviv Ultimate Serum won’t ship for up to 22 days 😭. But excited to get it as well as my One Skin face. Thank you for such great in~ depth videos on these serums. Surely they will help my 61yr old saggy jowls and marionette wrinkles. I’ve never smoked, yet have had a few of my jaw teeth pulled in which has really caused loss of volume. Also waiting for the Axanthanine ( spelled wrong) to come back in stock. Thank you for your time in replying

@denise2534 Год назад

Sounds like great products! However, when they make the skin cleaner, I hope they make something that will dissolve mineral sun screen. It is So hard to get off of the face!!!😢

@brandi1294 Год назад

I’m a little confused on why a lotion type consistency of a peptide this dalton size would penetrate in real skin (not in vitro) even with a positive charge ? The response in this video didn’t really answer the question for me, at least not very reassuring. I’d love to see this products claims stand the test of time and long term clinical results. Thanks for the video and your transparency always Penny ❤

@PENNSMITHSKINCARE Год назад

I completely understand what you’re saying. Honestly it still confuses me a bit *but* what I do love is that they prove that it gets in on skin equivalent. That said-I’m all for long term testing too! I’m with you 😊

@charlottesometimes5195 2 года назад

I stopped using it because it made me break out. Is the normal?

@nanmax-hs8zy Год назад

Penny can One Skin be used after derma rolling or Microneedling?

@PENNSMITHSKINCARE Год назад

Cosmetic (shallow) YES!

@marlenehod Год назад

These scientists are saying using oneskin could help with inflammation and aging on other parts of your body. The scientist say blood tests they have done show this. Does the effects of oneskin help with inflammation and aging of the brain or should you take something internally? If so, what would be budget friendly and something that would help now.

@yomirabarreiro1088 2 года назад

Hello, what serum do you recommend for collagen induction? Thank you

@PENNSMITHSKINCARE 2 года назад

Do you mean when I needle for collagen? Just high molecular weight HA 💜

@yomirabarreiro1088 2 года назад

@@PENNSMITHSKINCARE yes, to reach the dermis to treat stretch marks, do you recommend any high molecular weight?

@vivixwaldo4227 Год назад

Can I use Oneskin together with Emepelle or NeoGenesis? Thanks

@PENNSMITHSKINCARE Год назад

I personally don't see any reason why not but you can always reach out to their amazing customer service if you have any questions about use!

@stephenbailey6878 2 года назад

I know I’m being annoying but are you still planning on the astaxanthin video? I’m looking forward to it!

@PENNSMITHSKINCARE 2 года назад

You are never annoying! I’m working on that video. It’s stinkin research intensive so it’s a project! 💜

@stephenbailey6878 2 года назад

@@PENNSMITHSKINCARE Yayyy. I can’t wait! I just want to make sure I’m utilizing my Skyn Iceland serum to the best of its ability. So I’m excited to see the video!

@Oooorileyy Год назад

Can you use this product in conjunction with other skincare products?

@PENNSMITHSKINCARE Год назад

Yes!

@mirandasworld 2 года назад

love your channel and you have the most beautiful striking eyes iv seen but now comes the negative part.....i dont feel that anything toipical can do what sculptra can do but i will still probably give it a try

@PENNSMITHSKINCARE 2 года назад

Oh I agree, sculptra is indeed in a league of its own!!

@mirandasworld 2 года назад

@@PENNSMITHSKINCARE i will still give one skint a try though as im sure it will help a lot

@amessina4333 2 года назад

Correct me if I’m wrong but it seems like Sculptra functions as more of an aesthetic difference (building collagen) where OneSkin is actually changing the skin at a cellular level…Making it healthier and more resilient which in turn makes you look younger. If given the choice, I’d rather my skin BE healthier than look healthier. Unless Sculptra has some benefits I wasn’t aware of!

@mirandasworld 2 года назад

@@amessina4333 lolol sculptra is a fertilizer that grows "deep inside the skin" growing your "own" collagen..it does not just change the skin with the sculptra glow it actually changes the shape of your face it augments your face back to the positions from like how you looked 2o years ago which a topical cream can nevber do it vlifts cheek bones jowls jawlines.and adds the volume you lost when you were young and makes skin glow like nothing else its a biostimulator and takes 3 months for results to show it then lasts 2 years and is a liquid facelift...instead of making yourself look ignorant and silly go and google sculptra then look at the before and afters and then go and read about what it does ,,,,,its done in a doctors surgery

@amessina4333 2 года назад

@@mirandasworld I’m sorry to have upset you with my comment it wasn’t my intention. I completely understand Sculptra’s benefits as I’ve researched having it done myself. My only point, and I think the one you missed, is that OneSkin is actually changing the health and resilience of skin cells, helping them ward off things like cancer and cell-destroying inflammation. Yes, Sculptra can help you diminish wrinkles and rebuild lost volume and collagen, but I would personally rather my skin (and my body) BE healthier than LOOK younger. It’s a pretty easy concept to understand. If I’m pretty in my casket, I’m still dead.

@PENNSMITHSKINCARE 2 года назад

For those who have difficulty finding the description box 😊 products links are below (affiliate)❤ OneSkin Code Penn20 gets 20% off OneSkin Face: shrsl.com/3h6by OneSkin Body: shrsl.com/3h6c2 0:00 Introduction 2:47 How DId the 4 of you come to meet and start OneSkin? 6:22 What is senescence? 8:17 What is the difference between OneSkin and supplements that help with cellular senescence? 9:49 What is the human skin equivalent? How does it relate to human skin? 11:30 What is the Molclock? 14:30 Where are you with the studies on OneSkin and its effect on systemic inflammation in the body? 17:31 How does the OS-1 Peptide in OneSkin penetrate the skin when it doesn't follow the "500 Dalton rule"? 20:24 Why did you decide to make OneSkin in the form of a lotion? 21:54 Can you explain the Hyaluronic Acids in your formula? Can you explain the relationship between OneSkin and menopause? How does it effect inflammation and how may it be beneficial to someone who is menopausal? 24:47 Can You Explain between OneSkin and menopause? 27:34Can OneSkin address hyperpigmentation? Are there any indications that it can help with melasma? 30:43 Can you address how OneSkin should be layered in a skincare routine? 32:35 Why is the OS-1 Peptide the last ingredient on the list? 33:45 How long does it take to see results form using OneSkin? 36:00 What is the difference between OneSkin and DNA repair products? 37:11 Can you explain the relationship between mitigating senescence and cancer? 41:45 Can you share if there are any more OneSkin products coming out in the future? 43:54 Can you elaborate on OneSkin body and how it can be beneficial to use over the summer? 44:30 When will OneSkin be available for shipping outside of the US?