Sickle cell anemia - causes, symptoms, diagnosis, treatment & pathology

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What is sickle cell anemia? Sickle cell anemia is an autosomal recessive genetic condition where the beta-globin protein subunit of hemoglobin is misshapen, which ultimately leads to a sickle-shaped red blood cell, which is prematurely destroyed and can get stuck in small blood vessels. Find our full video library only on Osmosis: osms.it/more.
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Опубликовано:

27 сен 2024

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Комментарии : 446

@gpsrandhawa8117 4 года назад

It was my Grade 12 final biology practical and my project was Sickle Cell Anemia. I watched this video a night before and it all went so good. The examiner was so impressed. Thank you 😊

@snehas9639 4 года назад

i am doing the same thing

@the_cracker_boi_4926 4 года назад

Lol mines 6th grade wow

@malikgaming3655 4 года назад

i have sickle cell anemia

@sportnewstv2749 3 года назад

@@malikgaming3655 me too, how are you dealing with your situation 😥

@aishwaryasiva4514 3 года назад

👏🏻👏🏻

@docsanti8971 4 года назад

WOW! Very well explained! Wish we had this kind of resources when I was at Med school. Well done!

@faijumusic1599 4 года назад

Check out my Sickle Cell Disease testimonials ❤️❤️❤️ Please subscribe to my channel!

@otet2004 4 года назад

😑 omg read the book is much details than this video a lot !! But what i love about the video is so brief and made easy

@xsx_kingx 3 года назад

Thank you so much this video helped me a lot I'm 15 and I'm trying to create a cure for sickle cell this video helped me get a lot of notes and I would love to text you and ask you some more questions

@monoromo 3 года назад

Good luck on curing it!

@cristamundil6697 3 года назад

What are you thinking? How’s it coming along? Don’t give up! That’s wonderful

@kimeilacampbell2694 3 года назад

Thanks! I wish you the best

@everydayshad 3 года назад

I would like the cure because I’m only 11 and I’m scared of death

@45_dhruvpandya20 2 года назад

Um I don't know if you're joking or actually serious. You're 15 and anyone can use the famous Phineas and Ferb line of "Aren't you kids too young for all this ?" But good luck to find the cure. I wish you success !!

@BillieB. 2 года назад

Very good video, I didn't come here to learn though because I unfortunately have sickle cell anemia. But I occasionally watch these videos when I'm dealing with minor pain as weird as that may sound it's comforting 😞

@osmosis 2 года назад

We hope that our video was able to help 🙏🏼

@splendidmercy6567 2 года назад

Thanks so much for the video

@Bassman7608 Год назад

Just lost a good friend to a sickle cell crisis. This video has taught me more than I could have imagined and I hope I could pass this on to as many as I can

@osmosis Год назад

We're sorry for your loss, Kevin. 🙏🏼

@anjalieabhayarathne6314 4 года назад

This was just so amazing! I had no idea that sickle cell disease was THIS easy to understand. It was very very clear. And I love the attractive pictures. And the narration was so good as well. Thank you so much!!!! Keep up the good work! 😁❤

@Afton_OnYoutube 3 года назад

@Daron Brown Aye, I do too

@patriciacole1117 3 года назад

No one should born with sickle cell today get tested get tested before you marry or get into a relationship please 🥺

@LSBUFU 4 года назад

Incredible lecture for nursing students like me. Thank you!

@Tanishdutt0007 Год назад

I watched Video of Renal Artery Stenosis and made my project of Class 11th And believ me My teachers were so impressed with me. They all appreciated me . But all thanks Goes to OSMOSIS, I LOVE ❤OSMOSIS

@osmosis Год назад

Wow! That's awesome! Thanks for letting us know, Mamta! 💕

@Tanishdutt0007 Год назад

@@osmosis Yeah!! but that's my mom' name. My name is KRRISH, by the way I loved you replied me after reading my comment. ❤❤

@sa21539 4 года назад

If only med school professors taught lectures like this

@prathameshagrawal2437 3 года назад

He himself is med school teacher biro

@adnaansheik7553 3 года назад

@Sameer Ahmed I agree with you bro. The ones in my Uni are so boring that you might wonder what the heck are we doing with our life and why we chose Medicine.

@genuine_meteen9169 2 года назад

Haha...so true, looks like most med schools professors byheart and spit in it in class Without logic.

@someone-jl9fu Год назад

professors in uni teach like shit they make me wanna kms

@IsmbbailBb89 Год назад

it's not a professional way of learning even if it's simple you should read and be aware of every little detail , i wonder what the face of medicine with students like you

@ايهاببيانو 3 года назад

Whenever we need to learn full medical information with fun and short time Osmosis is here to help. Thank you Osmosis from all my heart. I am the first on my college because of u ♥️♥️🎓♥️♥️

@osmosis 3 года назад

Wow! Thanks for letting us know! Our pleasure to be of help in your studies! 🥰

@reginaopoku2203 4 месяца назад

Splendid ! I'm a sickle cell carrier and this is very educative . God bless you. I'm watching you from Ghana. Wish you the best in life 🧬

@osmosis 4 месяца назад

Thank you 🙏🏼

@keziahaddoquaye53 4 года назад

I’m a 14 year old girl who has sickle cell disease that just wants to know more so thank you

@cryptomom3170 4 года назад

Love it!!

@cryptomom3170 4 года назад

Well I'm saying. Not that fact u have. I know what it brings my 16yr kld daughter has sc disease. It's just the fact that u want to know more!

@cryptomom3170 4 года назад

@Daron Brown stay strong! My daughter has SC disease she's not in & out the hospital as those with ss disease... But when she have episodes it's painful! Prayr to you all😘

@keziahaddoquaye53 4 года назад

Daron Brown stay strong 💪

@vet5838 3 года назад

@Daron Brown you are a WARRIOR! Praying for you always.

@khushboogupta8083 4 года назад

Your videos are really a great help in understanding the concepts.

@mariaragonese2543 2 года назад

I'm only here because one of my co-workers has sickle cell as well as one of my customers and I want to better service them. The man actually had jaundice and I had asked him if he was okay. He said he had sickle cell and outside of the fact that mostly black people and Native Americans get it I don't know much about it.

@RohitPant04 4 года назад

Thanks for always providing us with extra information on common BioMedical topics like this!

@gtgodbear6320 2 года назад

I have to get for blood transfusion post-op from internal hemorrhaging after getting an appendectomy. Hemoglobin levels just kept dropping and dropping all night. I had to have an emergency surgery and 4 blood transfusions to fill me back up with blood. Doctors were baffled that I wasn't dead. They had to cut me open like an old-time discectomy to find the bleeding and vacuum out all the blood. I had a staple puncturing a small artery at the appendix removal site. Closest I've been to death. Good thing they chose to keep me overnight or I would have died if I was sent home.

@fahadmunir892 2 года назад

May I ask Please Have you experienced a sickle cell pain crisis (also known as a vaso-occlusive crisis [VOC] two or more times within the past year?

@BillieB. 2 года назад

@@fahadmunir892 I have my friend, I also have SS

@easymedicinebytmd8247 4 года назад

Isn't it amazing that in heterogen allel situation this protects from malaria?

@charmaineframe7382 4 года назад

No. Not really.

@user-wt6hw5mi5q 4 года назад

Yes.

@shamaz1d 4 года назад

blessing in disguise

@namrata9235 3 года назад

It's the silver lining.

@iamcrocodile3148 2 года назад

It is amazing.

@srajan_shukla 2 года назад

Could I please please get the pdf of this presentation.... 🙏🏻 🙏🙏🙏

@xosupreme 2 месяца назад

Be real your here after watching supacell

@kenneth._.00 2 месяца назад

Lmao you got me

@kevinsteel7875 2 года назад

The editing and transitions are seamless, very nice very informative.

@osmosis 2 года назад

Glad you think so, Kevin! 💕

@23dayslater95 4 года назад

Im having a crisis watching this. I just wonder why my pain is so bad 😫😖

@guri9583 4 года назад

😂 make sure you drink water

@nasiahearts414 4 года назад

23_Days_later same

@TheMorrisonjamari 4 года назад

I hope you get better I have it too

@breakergirl47 4 года назад

First of all you have to change your mind set, telling yourself that you are ok and healthy. Then start eating only healthy food, I mean things that came with creation. You have to be alkaline. Alkaline body , alkaline food. Your cell has mucus in it and it has hardened, once you clean your body my eating alkaline foods, no hybrids or man made, the mucus in your cell will become soft and leave the cell and you will be ok. There are herbs 🌿 to use along with the diet and these herbs work only in an alkaline body. No meat 🥩 and drink a lot of Spring water a day. All the best🤗

@Tranquiboss123 4 года назад

Same

@danielkq 3 года назад

Hello from Brazil!

@nabukhanal6519 8 месяцев назад

my dad at the age of 70 got diagnosed with this . He had dengue few month back since then he had been sick n tired

@hkhk1901 3 года назад

I wish I had professors like you in university 🌟amaizing job

@theenglishfamily5375 3 года назад

Well appreciated... We look forward to more understandable videos ❤

@clarycluade666 3 года назад

I was born as sickle cell I pass throughout a lot of pain I thought my life as come to an end. I lost all my hope until a friend recommend me to baba ifa. BABA IFA thank u for my life may God continue to bless ur good work. no more pain or crisis I'm free indeed, U can so give him a try All u need is to believe +234 818 203 5968

@justrandom4304 4 года назад

Is sickle cell in anyway related to the repetition of getting blood clots coz I have some kind of anemia I just realized that I might have a blood clot near my lungs its a sharp pain when i take a deep breath. I'm going to see a doctor ASAP

@Stubborn214 8 месяцев назад

Hands down! the best lecture on SCD!! It was palatable ❤

@osmosis 8 месяцев назад

Wow, thank you! ❤️

@Abel-o4o 8 месяцев назад

My friend Sarah (that I have known since kindergarten) Has Sickle cell anemia. She says that is makes her small (which she is) And I hope it’s okay. She also said it makes you die at 50 - 60. And this really helps!

@mariaalma6563 4 года назад

Cramming for my midterms right now. This helps so freaking much. Thanks for existiiiing!

@Sarahwilliam455 2 года назад

I totally appreciate this Video, I'm in Nigeria and I was able to get hydroxyurea about two years ago which was really helpful but I've been finding it hard to see it in Pharmacies I'm Nigeria, Can you suggest how I can get this Medicine??🙏🙏 I'd appreciate a response Sir.

@akashkamboj1270 4 года назад

Sir this is the best video lecture I have ever seen Wish my teacher could teach like you

@sniyastanlyk7676 2 года назад

Beautiful narration and presentation ❤.. Loved it ✌

@osmosis 2 года назад

Thanks a lot, Sniya! 😊

@HolySteppaLM 3 года назад

i got tested when i was younger and i passed but i'm getting tested next week again. This sucks but the lord says" i know the plans i have for declares the lord plans for welfare and not for evil to give you a future and hope" Jeremiah 29 11

@manuelmorales2413 4 года назад

I'm sufferring a crisis right now on my left arm, I hate suffer this kind of pain frecuently 😢😥

@manuelmorales2413 3 года назад

@Nyla Davenport What is it recommended for?

@billrowe3350 2 года назад

My beautiful strong wife has Sick cell God bless you all who share this illness our prayers to you warriors!!!!

@fahadmunir892 2 года назад

Hope she will get well very soon.

@fahadmunir892 2 года назад

May I ask Please Have your wife experienced a sickle cell pain crisis (also known as a vaso-occlusive crisis [VOC] two or more times within the past year?

@gauri9319 4 года назад

Chages shape that allows polymerization due to which it forms Cresent shape???... didn't understand...!!!!

@zackabdihakim2737 7 месяцев назад

Thanks. Very well prepared and presented.

@alexanderksn2372 4 года назад

Thanks a lot for your videos! Maybe it was worth paying more attention to prime editing or CRISPR Cas9 or Cpf1 as an innovative approach to treatment?

@hanrubuhrmann384 4 года назад

This was a damn masterpiece

@zzs8948 3 года назад

Amazing content indeed ! But the type of hemolysis in Sickle cell anemia is mostly extravascular and abit less intra as far as i know , thank alot

@rahafabdelgafoor4002 3 года назад

Some informations in the video are correct

@munahiljaved2028 2 года назад

Very well explained in a much comprehensive way!!

@osmosis 2 года назад

Glad you liked it, Munahil! 😊

@SALMA-mq2os Год назад

You always save my brain from any additional requirements 😇 thanks

@osmosis Год назад

Happy to help! 🥰

@fasamah.kollie8767 Год назад

Splendid ❤ demonstration. A well deserved hats off 🙏🏻😊

@osmosis Год назад

Glad that you appreciate it, Fasama! Thanks! 💕

@semsem8801 3 года назад

Thank you for all videos

@zaidbasheer9152 Год назад

I was almost giving up until I saw this vedio ❤ Thank you very much

@osmosis Год назад

We're glad this helped, Zaid! ❤️

@ismailissifou2024 3 года назад

this is awesome and really helpfull, but could you be able (or maybe any reader) tell me what source was used for this vid?

@waleedkhalid6908 3 года назад

Thanks for your wonderful efforts

@omnaik5539 4 года назад

Thankyou for this important information

@dikshashelar2508 4 года назад

nice explain

@fatma3908 4 года назад

I hope that there will be an Arabic translation on every video📚👍🏼

@shefarivo2636 4 года назад

Why miss fatma??? 🤔

@fatma3908 4 года назад

To understand what he says

@shefarivo2636 4 года назад

@@fatma3908 لا يا استاذه الكليب طبي ولا داعي للترجمه من يريد معلومات عن الانيميا المنجليه لديه مواقع اخري للاستفاده ✋

@fatma3908 4 года назад

shefa rivo شكراً

@dr.rohanparmar10 2 года назад

please provide more information regarding types... beta zero / beta Plus Thal sickle

@osmosis 2 года назад

Thanks for your recommendation, Rohan! Our team will be taking this into consideration. Have a lovely rest of the week! 💖

@pgaspirant1228 3 года назад

Osmosis is the best thing that can happen to a medical student. ❤️

@osmosis 3 года назад

Thanks for your kind words! Always glad to help you in your medical journey!

@Jeene269 2 года назад

Thanks for the good explanation ✨

@osmosis 2 года назад

You’re welcome! 😊

@VampireDiariesBiebs 4 года назад

cant thank you guys enough!

@neisha4045 2 года назад

What is the reason for leukocytosis in SCD patients? Is this as a result of extramedullary haematopoieses?

@srirambhardwaj2343 4 года назад

Very.helpful.lecture.

@minaazeez1311 2 года назад

That was very helpful. Thank you.

@osmosis 2 года назад

Glad it was helpful, Mina! 💖

@mahekshah298 3 года назад

Textbook says its extravascular hemolysis not intravascular

@DermNerd808 4 года назад

Jaundice is skin yellowing?

@basharawwad7709 4 года назад

Yes getting pale

@abdullahmunir1994 4 года назад

not only skin yellowing many more other key sign and symptoms to declare as jaundice

@k1ngkanna568 3 года назад

I think I just figured out the way to cure this. So since sickle cell is caused by a mutation in the Hemoglobin cell, we can actually find a type of medicine that takes pieces from immature blood cells and uses them to reconstruct mature ones. To make this we can piece together a modified blood cell, if we use this I want it to be green, and the thing we can do with that is make it behave as if it is like a blood cell surgeon, or so I said. Basically what it would do is take immature blood cells, take pieces of those cells, and use the sickle cell's property of sticking to things to piece it back together. As for the defective Hemoglobin, we could inject new mature blood cells with non defective HGBN and basically program the green blood cell to take the good Hemoglobin and give it to a sickle cell. P.S: I AM 12 YEARS OLD AND I FIGURED IT OUT HOW DID NOBODY THINK OF THIS????

@MonkeyMan-co9io 2 года назад

They most likely have but usually the method of changing (injections, pills, etc) as well as testing for quality / side effects is a another complication

@sumathybalaji5252 3 года назад

Very nice explanation

@drlenton1746 2 года назад

thanks this is great workout in few minutes

@osmosis 2 года назад

Most welcome! 💕

@nozomiyomi1039 3 года назад

Wow thank you osmosis.

@Flanowa 2 года назад

Very informative! Thank you!!!

@osmosis 2 года назад

You are so welcome! 😊

@rubasarkez9917 4 года назад

Well done thank you so much 👍🏻👍🏻

@dataworkie 8 месяцев назад

Well appreciated on well explain lectures

@osmosis 7 месяцев назад

So nice of you! Thanks! 🥰

@julietnassozi9601 Год назад

I have sickle cell disease but i haven very sick since last year as am writing this am on a hospital bed and its been so bad my spleen got inflammated and its hurts really bad but what hurts most is that after a month of so much pain am treated like am a drug addicted ,or I don't want to go home ,or I just want drugs, or to be here , and some times the discharge me so early am tired the pain is too much I wish they would understand that the pain is too much and i need help

@5uhmmm Год назад

Hey, I hope you're doing well now. Bless.

@barshaacharya6783 Год назад

So informative

@osmosis Год назад

Glad you think so, Barshaa! 💕

@MuhammadAshraf-ig1qd 2 года назад

Informative and impressive Vid ❤️

@osmosis 2 года назад

Thank you, Muhammad! 🙌

@براءمحمدسعيدصادق 4 года назад

I love ur videos 🙏🏻

@iggsGH 4 года назад

Thank you

@brutallybrutal 9 месяцев назад

I am in crisis right now i need help

@toysfunny6944 4 года назад

Amazing Job thanks

@zindaginamilegidobara5366 4 года назад

Why calcium gluconate not use in sickle cell

@japjyotkaurahluwalia8957 4 года назад

Great job

@teamllama2884 4 года назад

I feel horrible for people who have chronic illnesses

@BillieB. 2 года назад

Thank you because a lot of the people in the comments are claiming that they have sickle cell , and that they somehow don't have it anymore which quite literally is impossible! JUST seeing this makes me feel better and like at least some people are taking it serious 😊

@jigarsolanki2499 4 года назад

Thanks sir

@rajeshwarijessy7776 3 года назад

Tq very much

@soriefofanah1445 2 года назад

What are the drugs of sickle cell

@BillieB. 2 года назад

What do you mean... Medication I know the main one is hydroxyurea or oxybridol. But for pain Ibuprofen and Tylenol will do and morphine if you have to go to the emergency room

@user-bw1pc2nf6d Месяц назад

I HAVE SICKLE CELL DISEASE, PLEASE HELP ME!!!!! IM IN SO MUCH PAIN :(

@Pro9pix Год назад

Is it same a E trait

@raicarab5246 4 года назад

Thank u so so much

@patrigodomingo4931 4 года назад

NICE ONE

@gelagelatin 4 года назад

Planning to take medicine, but I do not understand a thing:((((

@eyluldenizoglu4687 4 года назад

You don't start learning these stuff in medicine until you learn all basics that'll help you understand them first ^^ don't worry we all been there once !

@BillieB. 2 года назад

Yes and please make sure you actually care about the patients you'll be working with....... Handling this disease is not easy if you don't really care for it

@hamakurd3723 3 года назад

My College professors are totally shit and now i owe you for this favor

@jelu8852 4 года назад

bro you saved me... hope i get an A¡

@beautygirl6607 3 года назад

Hey are army 💜💜💜💜

@beautiful_nicole_3198 2 года назад

They give him that when he goes to his appointment

@apexlegends6142 4 года назад

Sorry for asking but isn't sickle cell anemia a autosomal codominant disease?

@EmmiBlox 3 года назад

This is too much for my brain to understand!

@Yungjelly954 2 года назад

I’m learning this just for the girl I like this is where simping gon lead you 😭 she a cool ass person tho

@agamsareen7621 3 года назад

Sir I have little pain in joints and I am 11 years old plz suggest Me something I am very worried

@BillieB. 2 года назад

First off if you're not sure you have sickle cell GO to the doctor tell your parents to get you into the doctor. Take pain medication and drink lots of water and also help if you use warm towels for your pain areas ☺️

@saeed_art Год назад

The best 👍🏻👍🏻👍🏻👍🏻❤️❤️

@JohnHolsn 3 года назад

*Sickle cell is an Extravascular Intracorposcular Hemolysis

@coraleeculbreath1246 4 года назад

I have sick o cell and it was making me stay up becuz it was hurting u lot I most die but I made it so yeah

@coraleeculbreath1246 4 года назад

Sick o cell I hate sick o cell

@agamsareen7621 3 года назад

Hi I have this disease and I am very worried about it

@fahadmunir892 2 года назад

May I ask Please Have you experienced a sickle cell pain crisis (also known as a vaso-occlusive crisis [VOC] two or more times within the past year? You may qualify for free clinical trial

@BillieB. 2 года назад

Make sure you are going to the doctor's as needed and stay hydrated and warm!!!!