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Small Molecules VS Gene Therapy, Will Rejuvenation Therapy Be Available In Our LIFETIME? 

Reverse Aging Revolution
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Dr. David Sinclair presents the progress of epigenetic reprogramming and rejuvenation in this video. He’s also answering questions on when he thinks the rejuvenation therapy be available in the Q&A session at the end of the presentation.
00:54 Presentation
25:42 Q&A
Chemically induced reprogramming to reverse cellular aging
pubmed.ncbi.nlm.nih.gov/37437...
David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins-protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction-as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.
Dr David Sinclair has suggested that aging is a disease-and that we may soon have the tools to put it into remission-and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives.
Dr. Sinclair’s official lifespan podcast / davidsinclairpodcast .
Original Video: • Epigenetic Aging and R...
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DISCLAIMER: The information and opinions expressed in this video are for informational purposes only and are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please consult with your doctor or other qualified health provider before start taking any supplements.
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22 апр 2024

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Комментарии : 62   
@ReverseAgingRevolution
@ReverseAgingRevolution 2 месяца назад
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@joshlocher71
@joshlocher71 Месяц назад
I like David sinclair
@susanc.2482
@susanc.2482 2 месяца назад
I believe Dr Sinclair's going to make it come true.💖💖🙏🙏
@joshlocher71
@joshlocher71 2 месяца назад
I like David Sinclair I heard about his chemical cocktail
@davidderidder2667
@davidderidder2667 2 месяца назад
The future belongs to the brave
@marjake3147
@marjake3147 2 месяца назад
I started following Aubrey well over 20 years ago and David for the last 10 years or so. It's a dream come true to see these 2 on the same stage sharing information in real time. I'll be waiting and watching for this possibility next year!
@trojanthedog
@trojanthedog 2 месяца назад
Same here. Good to see an Aussie so advanced in this field. Had to keep my thoughts to myself for decades about this because life extension was viewed as a crank belief for so long. Cat's out of the bag now!😊
@fogfog8388
@fogfog8388 2 месяца назад
Why is his photo so over-exposed and the photo shopping so obvious? To make him look younger than he is?
@megol0
@megol0 2 месяца назад
@@fogfog8388 Yes.
@JoeMama-ud5eh
@JoeMama-ud5eh 2 месяца назад
Based on the number of “Uh”s he said, he didn’t really seem prepared to speak in front of this audience, no? Just an observation. He knows what’s he’s talking about though.
@tuviafeldman1531
@tuviafeldman1531 2 месяца назад
@@JoeMama-ud5eh😮
@user-sn9eu5ni8l
@user-sn9eu5ni8l 2 месяца назад
Several years ago, I proposed using for rejuvenation the synergistic effect of two substances: a ROCK inhibitor, such as fasudil (approved in Japan and China), and an Arachidonate 5-lipoxygenase (5-LOX) inhibitor, such as zileuton (approved in the USA). Some chemicals found in trace amounts in food, as well as some dietary supplements, also have been shown to inhibit 5-LOX; these include berberine, baicalein, caffeic acid, curcumin ets Unfortunately, my proposal went unnoticed; no one undertook to test it experimentally.
@joshlocher71
@joshlocher71 Месяц назад
he is amazing David sinclair
@Seeker_of_sense
@Seeker_of_sense 2 месяца назад
This is highly interesting.
@ryanm9565
@ryanm9565 2 месяца назад
I'm doing a small molecule cellular reprogramming, age reversal experiment in a couple weeks
@UsYoungAgain
@UsYoungAgain 2 месяца назад
What’s the target? I’ve done a lot can advise
@ryanm9565
@ryanm9565 2 месяца назад
@@UsYoungAgain there is a paper showing LDS1 inhibition + tgf beta inhibition produced age reversal in the same fashion as the 7 drug combo from earlier chemical reprogramming Papers. How can we reach each other? RU-vid sensors any contact info in comments
@joshlocher71
@joshlocher71 2 месяца назад
what small molecule cellular age reversal experiment are you referring to
@ryanm9565
@ryanm9565 2 месяца назад
@@joshlocher71 The two molecule one he refers to at the end of the video. An LSD1 inhibitor and a TGF beta inhibitor.
@ryanm9565
@ryanm9565 2 месяца назад
@@UsYoungAgain I will be using the two molecule combo he refers to at the end of the video. An LSD1 inhibitor and a TGF beta inhibitor. I would love to correspond. Click my bio for the way to talk to me.
@user-oi6wi2di2z
@user-oi6wi2di2z 2 месяца назад
It will be through environmental exposure to frequencies 😊
@johndoyle4468
@johndoyle4468 2 месяца назад
I have a question. I am 66, I don't take any suppliments, I eat organically grown where possible and I fast for 15 hours daily. I have to wear +2 glasses to read small print indoors, so how long do I have to wait until you can restore my eyesight David.
@079Francvs
@079Francvs 2 месяца назад
1 semana, yo vi que el lo dijo en otro video... No recuerdo cual video, pero yo podría buscarlo. De hecho, el cuerpo entero con el coctel químico se podría rejuvenecer en 1 semana.
@joey9562
@joey9562 2 месяца назад
Totally cruel! First, he says that he doesn’t think they can feel it and then he shows us how the poor mouse is so scared it’s going to the bathroom.
@UsYoungAgain
@UsYoungAgain 2 месяца назад
Im 50 looking and functioning 35, biologist. I know it 100% is doable.
@polbzh
@polbzh 2 месяца назад
What are your secrets
@psyche7049
@psyche7049 2 месяца назад
@@polbzh He's desperate for attention and willing to say anything for views. Also, most if not all information he offers can be found for free on Google lol. Mystery solved.
@elizabethk3238
@elizabethk3238 2 месяца назад
I'm 76, told I look 20 years younger. Dating a man in late 50s. Perfect health. Best time of my life.
@UsYoungAgain
@UsYoungAgain 2 месяца назад
@@elizabethk3238 that’s really incredible! Now, I do a lot for my results, at 45 I was so aged, almost shaved my hair off as was balding. When people do it by natural means is amazing! Kudos
@UsYoungAgain
@UsYoungAgain 2 месяца назад
@@polbzh I’ve been researching the subject and experimenting in lab and myself. I talk ab it on my RU-vid and am reporting it of course. But there are technologies that can keep us younger
@wollahwollah1060
@wollahwollah1060 2 месяца назад
What's the summary
@UsYoungAgain
@UsYoungAgain 2 месяца назад
Depends. Was this talk before or after David sold his company with resveratrol patents to pharma giant GSK for 750 millions ?
@2coryman
@2coryman 2 месяца назад
I strongly doubt we can extend our lives much longer than programmed, but what we can do is to maximize longevity by by maximizing health and youthfulness, however, God may allow a science to developed to extend our lives much more❤❤
@ronilittle7028
@ronilittle7028 2 месяца назад
The Bible says we are supposed to live 120 years… Genesis
@joeblow1748
@joeblow1748 Месяц назад
Why the hell are you here then?? 🤪
@JoeMama-ud5eh
@JoeMama-ud5eh 2 месяца назад
Can we see a mouse that’s 5 years old or more? How about some yeast that’s a year old?
@Jessica-kk1cz
@Jessica-kk1cz 2 месяца назад
The naysayers are welcome to not use the technology when it comes out. Suit yourself. Your pessimism about where technology can go won’t be missed.
@viracocha2021
@viracocha2021 2 месяца назад
Yeah, I'm not going to trust any of this work until I see it replicated in several other labs. Neither resveratrol nor NR are that big of a deal.
@yannlang4849
@yannlang4849 Месяц назад
More fine words for nothing at all, and without anything concrete!!
@whatthefunction9140
@whatthefunction9140 2 месяца назад
The grifter extrodenar
@bejul2
@bejul2 2 месяца назад
What are these two chemicals??? Can you just tell down to which two molecules Pretty please!😅
@079Francvs
@079Francvs 2 месяца назад
Pídele la patente también 🙄
@bejul2
@bejul2 2 месяца назад
@@079Francvs I would ask for the number of the patent Absolutely. But I guess the answer will be the same 🤣
@079Francvs
@079Francvs Месяц назад
@@bejul2 lol 😂
@hbc511
@hbc511 2 месяца назад
Stop lii ing.
@user-jy2sz1jr9p
@user-jy2sz1jr9p 2 месяца назад
epigenetic reprogramming and rejuvenation in the words of a conman.
@079Francvs
@079Francvs 2 месяца назад
por qué dices que el es un estafador?
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