Subcutaneous vs Intramuscular Testosterone Injections: Which is better?

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Some evidence-based answers to this endless debate.
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5 окт 2024

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Комментарии : 258

@alexxxisbatman Год назад

This is the single best video on all of RU-vid for this specific topic.

@JacobWelch-xd6nh 11 месяцев назад

So which is the best so we don’t all have to watch 30 minute video for no reason

@manmedicine 11 месяцев назад

If you want simple answers to complex questions, this channel isn't for you.

@D_XDC 2 месяца назад

@@JacobWelch-xd6nh 🤡

@MariusvanDyk-q4n Месяц назад

fully agree, very applicable advice too, someone that's very good can simplify anything so that anyone is able go understand the concept.

@jones172 Месяц назад

@@manmedicine can i do subq with propionate??? King

@lotfibouhedjeur 9 месяцев назад

I clicked on this thinking I'd skip forward to the part where he answers my question but immediately fell in love with his nonchalant, straightforward, structured delivery. I guess I just found my new favorite channel.

@anonreview2419 8 месяцев назад

Dude are we using the same brain i clicked with the same intention and paused it each time i had to get back to work and finished it till the end my new doctor for sure hahaha!

@lotfibouhedjeur 8 месяцев назад

@@anonreview2419 He's like a breeze.

@MariusvanDyk-q4n Месяц назад

@@lotfibouhedjeur I think we are spoiled with instant gratification that Google gives, but their son RU-vid gives alot more depth, love this channel too, always great advice to be found.

@The_GenXennial 8 месяцев назад

As a former RN of 13 years I appreciate the lengths you went through to deliver this info. I went through nearly two years of chlomid therapy for infertility treatment. After completion of that I maintained well for a while with proper diet, sleep, and exercise regimen. However, (in my new career of 4 years) my work schedule flipped back to a swing shift 7 on 7 off nights to days. I felt the nose dive, and my recent labs came back with a 157 and Free of 6.8. I had discussed with my physician the possibility of subq vs IM. Your information definitely helped to inform me on a decision I feel that’s right for me. Thanks again! Hopefully I can get back to feeling like myself again soon.

@manmedicine 8 месяцев назад

Good luck. I work similar shifts, and they are brutal.

@The_Morepower 10 месяцев назад

Been doing daily SC with a 27 insulin pin the last month, after 5 years of E3.5D IM. Same dose. Feels like more energy and increased libido. Find myself waking up naturally without an alarm and not needing a nap during the day.

@DeadEnduro 13 дней назад

I’ve been doing sub q in the belly for 2 months and I keep getting hard lumps where I have injected

@joshparker1192 Месяц назад

This answered far more questions than I actually had initially. In fact answered something I had given up on searching about because no one seemed to have the answer. Very informative and helpful.

@ronreinert Год назад

Been doing daily SubQ for little over 15 years. Always steady levels. No pain at injection sites. I prefer fat pads around hip flexor area it absorbs better then belly with no lumps. No scar tissue.

@MrVaidas82 9 месяцев назад

HI . Had lumps on a belly ? How long does it took to disolve ??

@nicoc7024 6 месяцев назад

What’s your does and injection frequency?

@jdog5599 10 месяцев назад

Thank you Sir, exactly what I was looking for. Love the delivery, well done.

@dustyfeller Год назад

Very helpful. Outstanding job, Dr. Wingo

@jeffparr9675 Год назад

Thank you for your answer. Extremely informative. I am at the beginning of a TRT path. I started with Androtop/Androgel. I was not satisfied. But I kept it for a year just to see more long term results. Now biweekly intramuscular injections of Omnadren (Sustanon). Results are pretty much incredible in all areas: sexual, mental, psychological. I am not sure if it is related, but hypotension and bradycardia that developed some few years back are gone. Once again, thank you for your video.

@manmedicine Год назад

Excellent. I'm glad to hear you are on a protocol that is working for you.

@AConservativeView Месяц назад

I injected 125 mg Sustanon into my quad with a 29g 1/2" and its been 3 days and I can barley walk. It feels like a constant and extreme charlie horse! Is this normal? Is it less painful if I go deep Im with a bigger needle or is this the effect of sustanon in general?

@matthewparisano4316 4 месяца назад

Thank you so much. You are the best at explaining everything clearly.

@joef7647 8 месяцев назад

Hey Doc I just wanted to thank you for this video. I just started TRT (1 week ago) and I was unsure about IM versus subcutaneous injections. Also when you talked about the angles was very helpful as well!! I still have some questions about drawing from the vial with a tiny air bubble that I can never get rid of. But thank you again for all the information, it was extremely knowledgeable and also the way you speak is relatable, not arrogant. And thank you for your service 🫡

@manmedicine 8 месяцев назад

Thank you. Good luck with TRT and don't worry about those little air bubbles.

@rackpull772 Год назад

Your channel is great man, definitely keep it up. Only a matter of time before you have a ton of followers.

@johnmoore1495 Год назад

In my experience with SubQ the lumping risk goes up with the more volume you inject at once. 0.5mL I get a lump probably 50% of the time. I choice subQ because it showed a lower E2 and higher total test in the trough compared to IM from the studies I had seen 2-3 years ago. Presumably due to the slower absorption. Plus it just put my mind at ease, don’t have to worry about injecting into veins etc.

@JRR100 3 месяца назад

You never mentioned that because with subcutaneous injections you can use a tiny insulin needles which are painless and quick, you can break up your dosage into small daily doses to mimic your body’s natural testosterone delivery and smooth out the peaks and valleys.

@michaellukar2201 6 месяцев назад

Hi Doc . Just to let you know I’m injecting test Cyp and a small dose of Deca micro dosing every week subconsciously and it’s awesome. Better then intramuscular. I use the small diabetic syringe and put the small bottles in my pocket to warm them up so it’s easier to draw through a very small needle. I have no scar tissue issues and it’s less painful to inject . I normally inject at two places to split the doses up . I have no aromatase issues at all and found out it almost simulate your own natural slow testosterone release in to your body . I’m 65 of age and put on some nice lean muscle and train just as hard as the younger guys in the gym . Mind you I have been training since I was 16 years old and have competed in bodybuilding competitions in the 90s so I am familiar with the drug side of the sport but on small doses. But I find now I feel the best I have ever been. ☺️👍

@albertlewis4407 2 месяца назад

thanks so much for the comparisons of subcutaneous vs intramuscular injections. i was taught to use subcutaneous, and that hitting muscle was to be avoided. then i saw many testo. videos showing ONLY intramuscular. you cleared up my confusion, and thank you for that!

@KeithBerry-lp9gb Месяц назад

This video has convinced me to try my first subcutaneous injection tonight!

@ziggysplace3858 29 дней назад

How's it going for you?

@joshparker1192 Месяц назад

I do subcutaneous injections of TRT 60 ML twice weekly with ½" 27 gauge needle as well and unfortunately I do have sensitive skin and get the hard (reddish) somewhat itchy spots. However they usually only last about a day or so after the next injection (4-5 days) so I feel I can tolerate that over the additional discomfort of IM and/or the possibility of scar tissue as you mentioned. Very very good video. Keep it up!

@yahn3625 Месяц назад

u mean 60mg ?

@matttsmith733 Месяц назад

14:32 I say this with all respect to the LGBTQ community because it is not their fault, but we have a healthcare system that very easily gives testosterone to transitioning women, but biological males often have to go through months of monitoring and testing at extreme expense, delays due to referral needs, long waits to get into endocrinologists. At least that was my experience.

@criis651 22 дня назад

@@matttsmith733 I agree. I had all the symptoms of low T. My endocrinologist prescribed me Phentermine. I never went back to him.

@jmiller9455 8 месяцев назад

My total T was lower and E2 was higher when I switch to subq. I also increased from 100mg/weekly to 120mg/weekly and increased from 1x to 2x a week. I'm trying shallow IM in delts now

@yuriortega809 2 месяца назад

Thanks for such informative and well-explained videos. We truly appreciate the effort you put into it! 👏👏

@manmedicine 2 месяца назад

Thanks so much.

@gunterlugo3185 6 месяцев назад

My endocrinologist prescribed Xyosted 50mg every 5 days. My endocrinologist billed it as 50mg 2x a week for insurance purposes. I have great insurance and they approved that frequency vs every week and I pay $0 a month. I have been loving Xyosted for the ease and convenience, but I understand that it is a fancy auto-injector and a pharma money grab. My endocrinologist said that Xyosted has been relatively becoming a bit more popular, but not commonly prescribed. Amazing video - appreciate it.

@MontezumasViper 3 месяца назад

Big money grab for sure. All that cost gets spread out and adds to everyone's bill. Enanthate is inferior anyway since Cypionate lasts longer and can be done more often (and is super cheap). My guess is that they chose that ester just so they could sell more shots due to the sharper peak and trough. Big pharma is a scam.

@alejandroguerrero5425 2 месяца назад

Very clear and easy to understand info. Thank you

@samwillow264 7 месяцев назад

Thanks Dr Wingo, fellow doc here, been on trt x 18 months tried the subq method and noticed a fairly noticeable drop off in multiple parameters (libido, strength, focus and energy). Went back to IM method and things turned around quickly. Interestingly, as I reverted back to IM method my HGB jumped up to 18/HCT 51. Free T jumped way up. I theorize that my SHBG decreased when on subq then when switched back to IM (same dosage) then free T climbed substantially. I know anecdotal, but my colleague noticed the same type of decline when trying subq method. Thanks for your vids, greatly appreciate your time and knowledge. 💪🏻💪🏻💪🏻

@samwillow264 7 месяцев назад

By the way I rotate injections sites with 4 different regions of muscle.

@progressthroughpain 6 месяцев назад

Interesting. I have been alternating between subq and intramuscular, using t.propionate. Which ester are you using by the way?

@Sisu2280 3 месяца назад

IM works fine... 3x week, four sites, rotated, 27g 19mm needle into quads, 13mm into delts. Shallow into both muscles. Zero pip. Zero infections. Swab everything twice, wash hands... I hate the oil sub cut.

@quix99 Месяц назад

If shbg goes down, free goes up. Other way around

@davidpoplin6344 Год назад

Thank you for a great educational video. I currently inject testosterone cypionate twice per week using a 27 gauge needle into a muscle. This relatively narrow gauge needle is far more comfortable than larger diameter needles and may ultimately produce less long term issues such as scarring. I have also found that needles from different manufacturers can vary widely in how comfortable they are to use. Not all brands of needles necessarily have an ideal sharpness for comfortable IM injections.

@markmelchi8416 Год назад

You can even warm up just above room temp using warm water, it thins out the testosterone, and I even use insulin needles!

@2K9s Год назад

Use a different (larger) syringe if you’re worried about sharpness. Love using 25g 5/8” in my shoulders… fresh receptors.

@astarpery6260 Год назад

@@2K9s How does the larger syringe help? because more weight pressing down on the needle to make it pierce better?

@2K9s Год назад

@@astarpery6260 I meant to say use a thicker gauge needle for loading the syringe of your dose. Then replace the needle with whatever gauge you like depending on location. A fresh needle goes in (pierces) easier and comes out way smoother vs the same needle to load and inject. My loader needle’s are >21 gauge. I’ve also started using insulin syringes to micro does sub q using one syringe and it’s awesome. Watch a video of how needle tips bend under a microscope just from loading meds.

@astarpery6260 Год назад

@@2K9s ahh yes, I always swap between loading and injecting. Wouldn’t dream of using a thin gauge to draw, just don’t see the need.

@997sPorsche06 Месяц назад

I use Xyosted 100mg week. It works great and is easy to use. I am 63 and my test level stays around 900+

@frankb7811 Год назад

in the quad with an insulin needle. no pain, no bumps. I inject every day .2 cc alternating. no side effects at all with TRT Pharma grade Test Cyp.

@jessejames2334 Год назад

This is most likely the path I will go… seems much safer & more effective

@AConservativeView Месяц назад

@frankb7811 Месяц назад

@@AConservativeView it's normal bud...try the buttcheek in your next rotation and spread the amount in half on both cheeks. hope it helps. PIP in the quad is common. That's why i use insulin needles...no pain at all.

@Whitey_Ford Год назад

Preciate you posting this. This is precisely what I’m trying to figure out. Thanks 🙏

@manmedicine Год назад

You're welcome. Glad to hear it was helpful.

@Whitey_Ford Год назад

@@manmedicine most certainly. It makes sense that it can flow different through your body at diff rates with the IM. That the SUB q keeps it always the same evenly distributed. A lot of the TRT clinics act like you have to do it IM. Why I don’t know 🤷‍♂️. My cyp 200 is in Grape Seed oil. Hopefully it won’t be to thick to run smaller needle on sub. Only way to know for sure is try it I guess !! I feel much better that I won’t be wasting it doing sub q. I’ll be taking the Gonadorelin .5ml 2 x a week. The test cyp is 1ml every week. I can do it in one shot or split it into 2 !!!

@chadgoodyear7905 2 месяца назад

Thanks. Good video. I’m on day one. Just injected IM with a 29 gauge half inch into the deltoid, and that felt fine. I’m trying to research alternative approaches (to mine) to avoid the algorithm echo-chamber. My wife is a clinical massage therapist specialising in deep scar tissue, I’ll tell her you said she has to give me a shoulder rub every day 👍

@joshparker1192 Месяц назад

29 gauge? That had to take forever. Even with 27 gauge it's a long process with how thick the TRT and oils/preservatives are. I would certainly be curious as I've never heard of someone using 29 gauge

@xjumpmaster82 Месяц назад

@@joshparker1192 I use a 31g. A few extra seconds. No biggie.

@Gallagher.661 Месяц назад

I used xyosted for about a month before switching to subq cypionate. The biggest reason I went with xyosted was because this was my first time injecting any medications at home and I was pretty nervous. I was hoping insurance would take care of any financial differences but my 75 mg of enanthate once a week was 150 bucks for the month. About week three I felt markedly worse and I was very quickly switched to cypionate twice weekly. We're still early but I'm hoping it all evens out soon. I believe the only benefit I got from that first treatment was a gentle introduction to needles, but after my first few self injections I'm realizing it's not that bad in general

@ziggymorris8760 Год назад

I use Xyosted 100mg per week, just started so I’ll be back to share blood work.

@akleo78 8 месяцев назад

Can you give us an update? I am also on Xyostead 100mg, week #4 and so far is working great for me

@Deal4itTanny 5 месяцев назад

Thank you for the awesome info. Really helpful.

@goingtocalifornia 3 месяца назад

Backload the slin pin. Can easily use a 29 with an mct oil solution.

@GuyDMcCardleJr 2 месяца назад

Thanks so much for this. Exactly what I needed to know.

@manmedicine 2 месяца назад

You're welcome

@robertlulek1634 6 месяцев назад

Why even draw up the solution with the insulin needle? I simply carefully takeoff the plunger of the insulin needle. I take a regular syringe with a 22 gauge needle and fill it and load up my insulin needle as needed. Then I put carefully back the plunger, being careful not to push it through the needle, it does not come out if you tap it and put the plunger on and turn it the right side up. This works great and you do not have a dull injection needle. An insulin needle will hold roughly one milliliter. So you can fill it up halfway that would be a half and then inject another part of the body with the other half. It's real quick efficient and easy not as long either to do it this way.

@hoodcnicholas 4 месяца назад

Surprised to not hear more from you regarding spikes and drops in levels typically seen with IM every 3 days or 1 times per week versus what is becoming increasingly popular with SUBQ micro dose daily. Any thoughts there Doc? Thank you

@works2travel359 Год назад

Best breakdown injection vid I have found yet. And trust me I've seen hundreds. Thanks for taking the time to put that together. My question is, if and when you first start TRT and they start you on a smaller dose to begin with, is there a chance it might lower your free T levels if it's not enough. So for your first 8 weeks for example, prior to your second blood test if the initial dose is to low is there a chance your T levels go down because your natural T is turned off and the TRT dose was not enough to bring you up past your natural T levels. Hope that makes since, thanks again.

@watchingyoutube7330 3 месяца назад

Great video. Thank you. You were talking about 1" needles for "Fatties" and IM's. Well, I'm almost one of those "Fatties" and I was thinking of using a 1 1/4" 27 G needle. Does the extra 1/4" concern you? Thanks.

@vezeris 11 месяцев назад

I don't feel a thing with 1 ml subq. It was like a revalation!

@robertshort9121 Год назад

Yes drawing into a syringe with a 27 ga or 29 ga can be quite slow. But you can get a vial adapter that allows you to draw your test out of the bottle without putting the needle into the vial using a luer lock syringe. Then just draw your test and put your luer lock 27 ga half inch needle (have never found a 29ga half inch luer lock) back on the syringe and you're ready to go. My pharmacy sends me a new vial adapter whenever I get a new order of test.

@terrymedlicott3580 11 месяцев назад

Draw with green needle....inject with blue

@echstacy1652 7 месяцев назад

It honestly doesn’t matter you can draw with the needle you are injecting 😂 ppl use insulin needles for test

@marcchatow9516 11 месяцев назад

I started using Xyosted a few months ago. Definitely more convenient to use, vs. IM. I've only had a few issues where, about after a week, it felt like it created a nodule at the injection site with some minor pain when I would touch it. Another time, I must have hit a vein because it created a bruise where you can see black & blue marks underneath the skin.

@nicoc7024 6 месяцев назад

Still issues with nodules?

@miltonjaramillo9731 5 месяцев назад

How did u get insurance to cover XYOSTED or u paint out of pocket my insurance does not want to cover it as for other testosterone they will.

@MontezumasViper 3 месяца назад

Xyosted ends up being a huge cash grab for the doctor, pharmacy & drug company that gets spread across insurance and costs everyone a ton of money. It's test E put into an autoinjector - they've created nothing new... Test cypionate is better (longer lasting more stable injections) - it costs me $15 for 20 weeks supply at 100mg per week.

@ianmcleod6428 Год назад

I was doing intramuscular TRT for a number of years. I hated doing it each week. However, my doctor wanted me to start subcutaneous injections. I've been doing this for about 4 weeks now. I no longer stress doing my injections. The benefits are so much better. Less issues, less pain, and I still get good results. I cannot call this a downside, but same may. The medicine/TRT sometimes gives a feeling of heat afterwards. This passes within an hour. Thank you for this video. Taking the time to explain this in detail.

@TaylorYarick Год назад

What's the volume of your injections? Do you get lumps from the injection?

@ianmcleod6428 Год назад

No lumps after injections since I moved to pinching skin around my belly. No pain, no stress. I do it in other places around the belly each week. I use a 25-gauge, 1-inch needle to inject. Although, I don't use the full inch. Just enough to get under the skin and go slow. I do this around a 90-degree angle.

@MrVaidas82 9 месяцев назад

@@TaylorYarick I do the same but get lumps. It hurts only for 3 days but somehow even after 3 weeks i think i still feel lump which had have been disolved. Does someone have this problem too ?

@lukej7283 Месяц назад

That heat is most likely you havent allowed your alcohol to dry off after wiping the area

@rjdfit 6 месяцев назад

Thanks!

@tonystipstricks8299 6 месяцев назад

U can back load an insulin syringe with a regular syringe. Pull the plunger out, fill the syringe and slowly, carefully put the plunger back in.

@BadUrbanKarma 9 месяцев назад

Thanks for the information. I'm converting from 1 per week IM to twice per week subq, after talking to my doctor. Appreciate the education.

@nicoc7024 6 месяцев назад

How’s the subq going?

@ytlongbeach 8 месяцев назад

I'm doing TRT with IM injections, and much prefer subcutaneous injections, so I'll try that next cycle. Thx for this vid !!

@sgturn1500 3 месяца назад

great video, i never understood why the docs were pushing IM. I wonder if glut injections will work the same way

@DazePhase 11 месяцев назад

Very well explained. Thank you!

@StelioKontoss Год назад

I had nodules and PIP almost everytime in any muscles from IM, switched to SubQ micro dosing and wow, don't feel a thing its so easy! I draw with a 21g so its very quick then switch to 27g 1/2" works like a charm! Waiting for bloodwork for my levels but im not worried about it. Very informative, great video!👌🏻

@DaveyDays Год назад

What location do you inject

@daMillenialTrucker Год назад

@@DaveyDayseverybody I see, pinches their lil belly fat and JABS IT IN and then plunges the medicine in. From my understanding you can do it anywhere on your body where there's body fat

@tortillachip2342 Год назад

Did you get your bloodwork back yet? When you do can you share if the levels are the same as your IM levels. Thanks

@BichoPapao77 9 месяцев назад

@@tortillachip2342upp

@BichoPapao77 9 месяцев назад

Uppp

@tzahi12370 Год назад

A question: If the peaking time of IM injection of test E or C is about 24-48 hours after the injection, whats the peak of the SubQ injection of the same esters ? Thanks.

@BichoPapao77 Год назад

Upp

@JimmyKay1976 7 месяцев назад

Excellent presentation as always. Would the body absorb that same amount of Test from a SubQ injection versus IM injection? Also, assuming I understood correctly, would SubQ injections have a more "gentle" effect on HCT given the slower absorption rate?

@SpikedBoost63 Год назад

Another great video! Thanks for the resources. I will point out Test vs. DHT vs. Estradiol levels in the transgender IM vs SQ 1000mg injection reference. The chart was extended over 12 weeks. I think it is very clear that at the 1 week mark which is when most of us inject (typically sooner/bi-weekly) there is about a 15-20% increase in DHT levels over IM route. Have you uploaded a video on DHT and it’s effects on libido yet? If not I’d love to hear your input. Thanks again for the great work and keeping it EBP!

@manmedicine Год назад

Thanks. I agree with you regarding the DHT bump. Due to time constraints, I didn't include it in the video, but the SC enanthate study showed near identical testosterone to DHT ratios with IM delivery. I'm not sure I believe that, but I thought it was interesting.

@tonehernandez8598 4 месяца назад

DhT goes higher on IM ?

@30rdmaga 3 месяца назад

My urologist prescribed me the zyosted 75mg and my insurance wouldn't cover it. I called his office 5 times and made sure he switched me to a generic. The auto injector was nice but for $150 a month it definitely wasn't worth it.

@manmedicine 3 месяца назад

I agree. It's overrated

@willferguson3956 7 месяцев назад

Xyosted makes it quick and easy, it’s worth it if insurance is the same. It works well for me.

@brandonyoung4910 11 месяцев назад

Backloading insulin syringes saves a ton of time and tiny needle dullness as well.

@robd9819 9 месяцев назад

I initially started out doing IM with 25g*1" and then switched to shallow IM with a 27g*5/8". Quad injection. Long term A little less trauma to muscle area and less waste of T in the longer bigger G needle. 27/ 5)8" are a little harder to find most are 1/2" which I use too.

@josephsantana3094 3 месяца назад

You do the 1/2” in your quad as well? And still get shallow IM? I’m about to start TRT and thinking shallow IM with insulin needles is gona be the way to go. I’m just concerned about not reaching the muscle and ending up doing unintentional Sub Q. I fairly slim though with minimal fat.

@robd9819 3 месяца назад

@@josephsantana3094 1/2 in the quad works I prefer 5/8" . I tried SubQ but not a fan of it.

@rickf4401 11 месяцев назад

I use an auto injector from Spark Hormone Therapy for IM injections. It works great! I hate needles and the injector makes the process so easy.

@EarlofGreystoke 8 месяцев назад

where can I found to purchase that injector, thanks

@wa2k360 6 месяцев назад

Thanks Dr Mike israetel

@PetarPenava 5 месяцев назад

Great video

@niabv2 10 месяцев назад

if anyone is wondering if its ok to subq sustanon, i can tell you it absorbs the same way like any other ester and I personally observe zero difference in terms of pip/serum levels.

@manmedicine 10 месяцев назад

Yes it works just as well

@rackpull772 Год назад

Have you seen cases where less injection frequency is better? I'm seeing a move among people who tried frequent injections to go back to less frequency, citing the extended time it takes to break down a larger depo, ester half life, psychology of not thinking about TRT every day, and overall compliance.

@manmedicine Год назад

Not better per se in terms of effectiveness, but "better" in terms of identical symptom control with less needle sticks per week.

@Billy_K. 11 месяцев назад

@@manmedicine i pin ed now that i have some decent amount of fat to avoid excess AI and high e2, but when i get down on bodyfat perhaps i will try eod

@johnh7745 9 месяцев назад

Wow some of that you must be talking to other docs because some of it's going right over my head. It's like pulling teeth with my doctor to get generic Viagra and a mile of testosterone they give me like a amount every two weeks on both medicines and that's supposed to make me happy.. I wish you were my Doc. I just started doing Im injections on on myself and there's barely enough there to get in the it's just real difficult when seeing guys all over the internet injecting all this testosterone and getting Viagra when they're.. I just don't I'm going to be 65 December 31st and I just feel like I have a spark of life in me now that I'm getting testosterone and Viagra generic..

@michaelshepler1018 7 месяцев назад

Great info! Thank you so much! You answered far more questions than my prescriber could. I may have missed this, but do you recommend splitting a weekly 100mg prescribed IM doseage into two 50mg SQ injections per week?

@ABhd84 7 месяцев назад

Great video thanks

@domZizz 6 месяцев назад

Saw someone mentioned the pellets as a future topic and itd be great to see you cover bio identical cream as an option too. I apply daily and saw my total T level soar above 'top end' range here in UK but with no alleviation of symptoms, which for me are mostly mental eg brain fog, rollercoaster emotions. Doc advised injections but as its only been 3 months im going to give it the same amount of time again to see if my body adjusts. Lastly i bought your lifestyle/workout book a few months back and wow the HIT workouts are killer...first session I had a chest and back pump like never before and i have been lifting decades. That was 20 mins in the gym and at that point i was done. Im more ecto/meso as per the guidelines and so rotating between a fat loss and bulk period. The book is awesome and your authenticity really comes across well. Cheers

@Zen36977 6 месяцев назад

With SubQ you can break up your dose into several jabs per week. No nodules with smaller dose…massage the site a little and all good. More steady levels as well

@ralphg3454 Год назад

One inch needles are way too long for my thigh. I almost always hit nerves. I switched to 1cc syringes, and it's much better. No lumps under the skin either. Testosterone was 220 in December it is up to 1100 as of April 3rd

@manmedicine Год назад

I agree. Way too long. And IM injections in the thigh just hurts. I'm not a fan.

@Joe_Friday Год назад

I've been going subq once weekly around my love handle for a while now. I swapped ever since an uncomfortable experience I had while injecting into my quad. I stuck the needle in and the muscle raised up really high and peaked into a mountain shape around the needle. It didn't hurt much worse that normal but it felt very strange and I got a bit nauseated when it happened. I suppose it was the muscle spasming. I've never seen anything like it.

@andrewnormore7093 Год назад

@@Joe_Friday this just happened to me!!!! I had 2 weeks of injections but took an hour to work up the nerve to inject…. Then I hit a nerve and can’t bring myself to do it again :(

@Joe_Friday Год назад

@@andrewnormore7093 That's crazy! So you truly experienced the same thing I described? It made me nauseated.

@andrewnormore7093 Год назад

@@Joe_Friday Yes dude same here. I looked down and my leg muscle looked like it had worms! I had to massage them down. I just ordered 27 1/2" and 29g 5/8" for subQ injections. They appear to be the way to go. IM TRT Looks like its kind of out dated. But also possibly that guys are injection "other stuff too" that has to go IM, which is why they still do it. I've seen so many comments about crazy shit happening from IM injections 2-6 years out. IM seems to be.... bad for you.

@SteveAustin77 6 месяцев назад

12:38 that graph and other graphs on testosterone enanthate (like on the Xyosted website) lead me to believe the typical halflife is probably around 10 days, not the 4-5 days I often hear people say.

@Fitplatform 9 дней назад

Do you think Sustanon 250 is suitable for subcutaneous injection? I take 3 boxes weekly for bodybuilding. Can I spread it over 7 days and take small doses?

@pv8340 11 месяцев назад

Hey Doc, I have been prescribed XYOSTED and well, let me share my experience and labs. While its very convinient by just opening the pen and injecting yourself, its extremly expensive. I also found that my red blood cells went up while on it. Something that didnt happen with test cypo. I do use insulin syringes to give my weekly dose of test cypo and like it alot better than the intramuscular as I had to go to docs office myself because i was to chicken to do it myself...but with insulin syringes, much better. My levels I find to be more stable and dont experiences highs and lows. Oh, blood pressure also went up with xyosted for some reason. Perhaps the ethanate, you would know better than me. Anyone reading this, i would not pay for the xyosted, too expensive, and mostly a gimmick. Doesnt do anything different than the regular way except convience. I would like ask, as far as insulin syringes go, which is the best for injecting and whats the most you can inject sub q of any substance?

@manmedicine 11 месяцев назад

I use 27g insulin syringes. Generally 1 ml is the max

@akleo78 8 месяцев назад

I am doing great so far on Xyostead. Cyp gave me very high blood pressure 155/100 and my doctor switched me to Xyostead. I am on week number 4 and feeling great. I haven't seen a significant increase in my blood pressure and no noticeable water retention. With cyp IM injections, my face looked puffy and round. Xyostead is not on the list of preferred medications by my insurance, but they still cover most of it, and I pay $60 out of pocket. Xyostead also has a plan now for people whose their insurance doesn't cover it m. I believe it is around $150 per month.

@billscott6819 8 месяцев назад

I've been on for about 9 years and did delts, glutes and quads IM for about 8. I switched to sub-q when I started getting infections IM. It was strange, like my body started to reject it, and I'd get a dermatitis type of infection if I shot IM. After two rounds of antibiotics I decided to start sub-q, and it's been fine aside from what seems like more bloating in the abdomen, where I administer. I'm trying to get the right balance with small amounts of aromasin. Getting monthly bloods now to nail it down.

@quix99 Месяц назад

200mg of test gets me at about 1700ng/dl either sub q or im. In 10yrs, i have tried everyway possible and best was always sub q daily with a 27g, just grab anywhere and go.

@hunter6099 15 дней назад

@@quix99 absolutely no reason to do it every day you can do Wednesday and Saturday and get the same or better results

@quix99 День назад

@@hunter6099 false. I have done this with my own bloods, everyday is better for better levels and lower estrogen

@marcbarbour7656 Год назад

Unfortunately after injecting for years the inflammation caused is just like food and toxin intake so every injectiin causes a inflammatory response as in calcuim build up in the arteries. When injecting sub into glute with slin pen my calcuim score has come all the way down to single figures. I find prop Ed the best wished I had done years ago. If u feel lumping then I use a muscle pulsator straight after inj to stop this 👍

@JeffR.-ne4zg 7 месяцев назад

Thank you for the video. My question is; why does it take so much less using subcutaneous vs IM? In my case, almost half the amount of testosterone when I switched from IM to subcutaneous

@dg9015 Месяц назад

Hello, I've just had my testosterone results from my GP UK 340 12.4 he said it was in range for my age 52 but told him I feel like crap but wasn't interested. If I go private what testosterone would you recommend please gels etc and how much to use

@Papanerf17 7 месяцев назад

Thank you

@daddywise7641 10 месяцев назад

Xyosted…. Expensive, but it works!

@Total_Body_Fitness_USA 5 месяцев назад

I use a 28g .5 inch insulin syringe and inject in shoulder or thigh area.

@okiok2535 7 месяцев назад

I don't know if this may be a thing but when I was starting TRT one of my ankle had a small amount of fluid buildup, as I have progressed with TRT subquestions injections this went away, now for whatever reason I have changed for intermuscular and the fluids/swelling is back ( have to add I had a small, cuff muscle injury, popped a muscle fiber and it is painful to walk) Anyhow this Lymph fluid transfer is interesting for me I think. I am going back to SC to see if that is relevant for me . Thank you for your knowledge and explanation.

@JmJm-px8wl 7 месяцев назад

Why is it that when I inject at an angle I get a nodule and a bruise? But when I go in normally, with no to very slight angle nothing

@dw4076 11 месяцев назад

What would your thoughts be on intranasel testosterone and Enclomiphene at the same time

@manmedicine 11 месяцев назад

I've never seen a study on it, but I think nasal testosterone is kind of a pain to use.

@launchpadmcquack4971 Год назад

Hey Doc, Loving the videos. Keep up the great work. I recently switched to subq after doing some research and I’m loving it so far. When I was combing the internet for info I found claim after claim that SubQ lowered hematocrit levels significantly. Some claiming as much as 41%. Is there any science to back this up? So far I haven’t seen it. Keep up the great work.

@manmedicine Год назад

Thanks. I've never seen any solid data showing consistent HCT differences and definitely not 41%.

@launchpadmcquack4971 Год назад

Hey man, I’ve started developing acne and I inject IM EOD. Would switching to SubQ potentially keep the acne at bay?

@manmedicine Год назад

I wouldn't count on it. It could potentially make it a little worse

@launchpadmcquack4971 Год назад

Thank you for the response. That’s what I was thinking as well with the DHT spike you spoke about. I’ll avoid SubQ

@HeyWattsUpCycling 2 месяца назад

if its so slow action then why do it daily? if this is the case then it would mean something like test C injections could be once a week and still end up being SUPER linear once your system gets acclimated after the initial starting point of a few weeks. Correct? ie a mild cycle of 250 test c + 150 primo? all one once a week?

@LoLHahaLolHahaLol 5 месяцев назад

Do you have to mix the testosterone different when you go into the fat instead of the muscle doctor?

@nicoc7024 Месяц назад

What made you switch to subq?

@rayortiz6189 7 месяцев назад

Hmm my dr had me doing sub q but a 15deg angle. Ill have to switch to 45

@Mab328 7 месяцев назад

I've tried subq both test e and cyp and both of them created nodules pain bruising unfortunately. No issues IM

@Dan-mr5cl 11 месяцев назад

Great video professional with loads of information , on my testosteron ethanate bottle it says intramuscular use only is this common on test enanthate bottles and do you think I can still inject subcutaneously?

@Billy_K. 11 месяцев назад

if i'm not mistaken in all pharma test brands is advised to do im, but obviously you can inject subq.

@Dan-mr5cl 11 месяцев назад

THANKS FOR INFORMATION I DONE MY RESEARCH AND I BELIEVE SUBQ IS FINE AND ARGUABLY MORE BENEFICIAL@@Billy_K.

@manmedicine 11 месяцев назад

Yep, you are correct. There are lots of studies showing it is safe to inject SC.

@timwenzel7272 Месяц назад

For L-carnitine injections.. I have a question ? subcutaneous or inter-muscular injection is there a difference? Do you get the maximum potential doing it either way is there any pros and cons of doing it subcutaneous or intermuscular with l - carnitine ? I prefer my stomach area injection but wanted to get your opinion. Is there any difference with the potency of the L-carnitine or speed of delivery? It’s not a waste of the product is it ?

@manmedicine Месяц назад

I'm not certain but I suspect there's very little difference

@PetarPenava 5 месяцев назад

Can you do a video on TB-500?

@gif24gt60 10 месяцев назад

Do u recommend 6mm or 8mm needle for subq testosterone injections?

@manmedicine 9 месяцев назад

I doubt there is a difference

@liamlynch2115 9 месяцев назад

Why would anyone inject IM if subq is just as effective?

@manmedicine 8 месяцев назад

Good question...

@johnk6757 10 месяцев назад

Not sure if this was covered in one of those studies, but because subq is absorbed more slowly the peaks and troughs should be smaller right?

@manmedicine 10 месяцев назад

yep, a little bit

@2gains 8 месяцев назад

Idk how to dose the subcutanous stuff. If I'm doing 500mgs of test e a week in two 250mgs 1ml IM shots. do I just convert that into the same two 1ml shots twice a week subcutaneously?

@leeptolemy 7 месяцев назад

What i know is that you can maximum inject 0.3 ml per subq sitting. If you do 2 ml a week (500mg) you can do daily 0.28 to reach same levels. Good luck !

@lund435 3 месяца назад

Hey doc, my question is can you draw and inject with the same insulin needle to do SC (perhaps dulling the needle for injection) or do you initially use a traditional syringe and needle say 21 inch to withdraw then switch out toa 27 g 1/2 inch for the SC into the stomach?

@manmedicine 3 месяца назад

You can but it does dull the needle a little.

@jackspintz5784 4 месяца назад

So when do you feel results after you sub inject? 1-2 days? When does it absorb?

@mastodonttix 7 месяцев назад

In studies deltoid injections peak lower

@David-z5e6w 11 месяцев назад

I just started the xyosted today my levels were 231 my urologist basically gave me a choice as to which route I wanted to go being a recovering heroin addict I didn't want to be loading up syringes and having flashbacks lol medicade is covering it so y not great job explaining

@akleo78 8 месяцев назад

How are you doing on Xyostead? I am on week 4 and so far working for mem. I will get my blood work in about 45 days but I am feeling great. I am paying $60 copay for 100mg.