Sir... as per Hindus and tamil tradition, 1.mother... 2.father... 3.teacher... 4.God...... God is after u sir... ur videos are life saving.... ur videos are like shadow in summer.... for students like me with lot of dreams and targets ur videos are the pathway that leads us to our destination.....
Excellent job!! Clear, succint summary with repitition to really cement our understanding! I would sign up for any and every science class you teach. I hope you are a professor somewhere - that's your calling!
Why does DNA polymerase not complete its direction with the fork direction .What is the reason for the opposite direction of DNA polemerase??? I hope you answer.
i think there's a small mistake. there should be no ssb on the leading strand because it can immediately add bases to the growing strand without having to worry about it going back to the complement strand.
im not clear about how the DNA polymerese manages to recombine the new strand in it is covered by the SSB protiens that prevent the connection.... dose it automaticly removes them in the process ? or there force is not a facter to the DNA polymerese ?
the free 3'OH is on the deoxyribose sugar of a nucleotide on the DNA strand that is being synthesized by DNA pol III or on the ribose sugar of a RNA primer nucleotide. it's needed bc that is where the newly synthesized nucleotide from DNA pol III will be added.
Are the videos suitable for somebody who is preparing for pre-med? I mean for somebody who wants to study Medicine? A friend of mine said that they are too detailed and are only for somebody who already started studying Medicine. True or?
Hi doctor, Thanks for your lectures. I want to ask a question : what is the direction of lagging strand ?? on which strand is the direction determined, the template or the new strand ?? I didn't watch this lecture, I just want answers for my questions. My regards.
accdg to campbell biochem book, lagging strand has its 5' end nearer to the replication fork than the 3' end. (Strands grow from 5' to 3' in the perspective of the growing strand). The lagging strand will grow towards the opposite direction of where the fork is travelling. So if the fork is moving towards the right, the lagging strand will be polymerized from 5' to 3' end but going to the left. The direction of the new strand is dependent on the template. If the template strand's 3' end is in the left, then the new strand will ofcourse has its 5' end opposite to the 3' end, which is on the left. From there, the direction could be either, I believe, just depending if its the lagging or the leading strand. I don't know if nature actually is so picky which strand gets to be the leading or lagging tho. It just so happens that that's the way we get to differentiate the two strands and their mode of polymerization.
Lagging strand grow from 5' to 3' end but in fragments that form continuously as DNA unwinds giving the overall growth of the lagging strand 3'-5' direction.
oo he's tan in this video, wonder where he got that tan from? was brains out partying in the sun? doing some yard work? guess he does leave his lectures sometimes 😂😂 maybe he does live a little
@@AKLECTURES LOL well that is good, I'm glad to hear it. A little is better than none at all, right?🤪 what an impressive balancing act that must be. Props Mr. brains.
