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The Future of Early Cancer Detection? | Jorge Soto | TED Talks 

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Along with a crew of technologists and scientists, Jorge Soto is developing a simple, noninvasive, open-source test that looks for early signs of multiple forms of cancer. Onstage at TEDGlobal 2014, he demonstrates a working prototype of the mobile platform for the first time.
TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and much more.
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14 окт 2014

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Комментарии : 116   
@conniesinclair2250
@conniesinclair2250 9 лет назад
Amazing.. We need this in the UK, I have lost too many family member's to Cancer.. It need's to change and hopefully this is the way forward.. But we need it now!! I shall keep following this and ensuring people know it's out there.. Thanks
@mastervader9796
@mastervader9796 9 лет назад
Jorge Soto and his team are an inspiration to humanity. To give this technology away for the good of "mankind" is a beautiful sentiment. I only hope now it will aid those in need.
@Itsallgoodtogo
@Itsallgoodtogo 9 лет назад
WHERE CAN I SUPPORT THIS!?
@TheJuliodarian
@TheJuliodarian 9 лет назад
My mind has been blown by how incredible this project is. We need to spread the word.
@sokra
@sokra 9 лет назад
As a survivor who has been missed diagnosed initially (which pushed me towards stage 2b by the time I was properly diagnosed) this has made me so happy...AND it's open source. Incredible.
@premier69
@premier69 9 лет назад
we're going to need much more frequent Nobel prizes given out.
@orviljuarez
@orviljuarez 9 лет назад
Excellent news!!! This will change too many lives!!! Thanks to Jorge Soto and his team!
@DeShyVu
@DeShyVu 9 лет назад
Thank you TED for these informative speeches. I love everyone I see on stage. I love this "coming together-ness". Humanity needs minds like these.
@SleepycoasterOrigamiUnicorn
@SleepycoasterOrigamiUnicorn 9 лет назад
Simple, short, sweet! I like this talk!
@aqibposeidon1135
@aqibposeidon1135 9 лет назад
Wow open source! May god bless this man and his team and may his aunt recover too..this isreal research coming from the heart
@gmadiva
@gmadiva 9 лет назад
Just shared this on facebook. Such an incredible discovery. The mind is an incredible thing, and BRAVO to those scientists who work so diligently for the good of mankind! This is very exciting! Congrats to all involved and thank you for your genius.
@harshawelgama8946
@harshawelgama8946 9 лет назад
amazing guys..all the very best..!!
@susanaoliva8186
@susanaoliva8186 8 лет назад
Fantastic work!
@starsnstrife
@starsnstrife 9 лет назад
This is amazing.
@maryyockey7983
@maryyockey7983 7 лет назад
As soon as I saw the title to this TED talk, I was automatically interested. Sadly, cancer runs in my family, and it always will unfortunately. I lost both of my grandparents to breast and lung cancer. Soto's talk hits home for me. Two of my aunts have also been diagnosed with breast cancer in the past as well. Meaning, when I am older I will have to get mammograms more often than the average woman. The way Jorge Soto started off his talk made me feel sad, yet also frustrated at the same time. He talked about how his aunt never smoked, drank, and played sports for more than half of her life. Which led me to my question, why her? Now, that doesn't go to say that I wish cancer upon certain people, because I don't. However, it sounds like she took care of her body, and cared for. Yet she ended up with cancer, why? I have always thought cancer hits those who don't see it coming, or you don't expect it to happen to. Which is sad, yet true. He also made a point that due to her lifestyle, that is why it took the physicians almost six months to properly diagnose her. I am not saying that they were in the wrong, because I wouldn't have assumed it was cancer right from the start, but six months seems like a LONG time! Exactly why when she was diagnosed she was already stage three. Have it being 2017 (2014 was when this video was published), one would assume that cancer would be one of the top things to check for would be cancer. Later on in the talk, it was mentioned that that a blood sample could potentially be used to detect early signs of cancer cells. if that is the case, that would be ground-breaking. I say that because more than usual, when people are diagnosed with cancer it is when the cancer has already reached either stages three or four. Which in other words, a point of no return. Not many people mention the word "affordable" when discussing the term "cancer". However at the end of Soto's talk, he talks about a clinical trial that is more affordable for patient's and their families. When someone is diagnosed with cancer, it can become a financial burden to the family that is affected. Overall, I agree with more than one point that Jorge brought up throughout his talk. I felt that he did a very good job, and felt that the non-invasive blood test sounds like a great idea.
@The_Limon
@The_Limon 9 лет назад
Thank you.
@dorkks26
@dorkks26 9 лет назад
Brilliant!!!! Not an open source. Great idea.
@alsu6886
@alsu6886 9 лет назад
***** They are still in very early stages or research and development, it's not even an alpha version yet, just the first prototype.
@dorkks26
@dorkks26 9 лет назад
You all are correct. It's not open source. I thought I heard him say it. Misunderstood. Thanks for the correction.
@alaaelddin5374
@alaaelddin5374 8 лет назад
great advanced work
@CanalHugoCosta
@CanalHugoCosta 9 лет назад
Amazing Idea man, thank you!!! Jorge Soto
@ClockinLoot
@ClockinLoot 9 лет назад
That's fantastic.
@Whoeee09
@Whoeee09 9 лет назад
This is incredible.
@MySherline
@MySherline 9 лет назад
Great news to us.. Cancer is way too common to be ignored. It comes to people who are young now. When older time it was more a sickness associated more with old age. Thanks for making it more transparent for us. Wishing u and team success in your research
@SanskarSharma
@SanskarSharma 8 лет назад
Hats off man!
@haochen7212
@haochen7212 8 лет назад
Amazing!
@ChemaRobles
@ChemaRobles 9 лет назад
Enhorabuena, Chile, Panama, Mexico, Israel, Grecia buen trabajo!! KEEP GOING ON!!
@tra09037
@tra09037 9 лет назад
Awesome!
@MillerKlaus
@MillerKlaus 9 лет назад
WHAT AN HONOR FOR MEXICO YOU ARE JORGE! CONGRATULATIONS!!!!!
@kotonizna
@kotonizna 9 лет назад
Goosebumps!
@dinayehia7140
@dinayehia7140 9 лет назад
It is a new approach to detect and differentiate between different subtypes of cancer, Happy we've started to do it in Egypt
@martinvargas236
@martinvargas236 8 лет назад
like like like like like.... Georgeus.... wonderful invention and investigation .... those guys are awesome they deserve a Nobel prize and all the support of medical community
@LenoahChacko
@LenoahChacko 8 лет назад
I totally agree with you
@alekseyalexej9665
@alekseyalexej9665 3 года назад
***accurate and affordable test that has the potential to dramatically change how cancer procedures and diagnostics have been done ... You only need one milliliter of blood and a relatively simple array of tools ... it can be routinely diagnosed at the very early stages ***What a promising statement! Loud applause! And where is it all in 6 years??
@theulair
@theulair 9 лет назад
Sounded too good to be true, did some research: Turns out only the device (basicly a camera stand) is "open source". The actual tests happening in the little pippetes are patented by Miroculus (according to their website). So it totally depends on them and their investors how "cheap" this actually gets in the end. It's likely that more patents are involved too. Secondly he didn't say how the actual test procedure works. Only how the results get photographed and processed. Is it as simple as pouring a few drops of blood into this? How does it need to be prepared? Can a normal doctor do this (quickly) or do you need proper lab equipment? Do doctors need to buy this from Miroculus aswell? Thirdly the images get sent to one single knowledge-based system for processing. This opens a whole new can of worms concerning patient data privacy. Will you be able to send your test in anonymously? Or are we basicly creating a huge biometric database of everyone? So yeah. I'd not celebrate yet. It's not gonna be a thing for a couple years anyway. But i sincerely hope they aren't lying and actually have something good. Fingers crossed.
@binhonz
@binhonz 9 лет назад
How can someone dislike this?
@Zzeo7
@Zzeo7 9 лет назад
@Jorge Soto this story really touched me, i will tell my family and friends ^-^. don't stop here do a kickstarter perhaps?! is there anywhere online i (we) can follow your progress?
@LoquaciousApe
@LoquaciousApe 9 лет назад
Very important talk. Though, I was hoping to hear about the software techniques used to classify the samples. It's fascinating to think of all the mathematical, computer theoretic, and physics discoveries that led to the development of the software that makes all this possible. Support basic research.
@DanielMadacDakke
@DanielMadacDakke 9 лет назад
Thanks Ted to doing that journey. I have no cancer and i hope i will never have but i know that infortunately maybe can happen . But if you continue whit updating this new revolutionary BioTecnology i hope that billion of people will have a more longer life and more happy memories whit the friends . I appreciate this amazing work and just hold on . Greets TED
@LYJManchesterUnited
@LYJManchesterUnited 8 месяцев назад
Hi please help what's the name of this device and is it available to buy? Where can I find more information online?
@xapemanx
@xapemanx 9 лет назад
this vid saved me cancer :)
@699nta
@699nta 9 лет назад
Fantastic. I know what early detection means.
@ralfprog3936
@ralfprog3936 9 лет назад
I want one ASAP
@tucopacifico
@tucopacifico 9 лет назад
This could be huge.
@LeonidasGGG
@LeonidasGGG 9 лет назад
"Oh, no! It's available worldwide thanks to 3D printing and it's open-source! Curse them!" - says every pharmaceutical company everywhere. lol
@dlSNOWWW
@dlSNOWWW 9 лет назад
Wow!
@MarcusPocus
@MarcusPocus 5 лет назад
2018 now.. what happening with this project?!? the web site miroculus.com not show any details about it!
@blak4001
@blak4001 9 лет назад
WOW!
@clearjaragon
@clearjaragon 9 лет назад
God bless his soul
@MrErmiland
@MrErmiland 9 лет назад
wow!
@DiamondSVPFree
@DiamondSVPFree 9 лет назад
Thank You God!
@comedycommon5110
@comedycommon5110 9 лет назад
Will this be able to be used for the detection of Alzheimer disease also?
@thetubeinsideyou
@thetubeinsideyou 9 лет назад
Thank you. To everyone working on this world altering project, I solute you. SCIENCE FTW.
@raitoe
@raitoe 5 лет назад
I consider this project such an important advance in the early diagnosis of diseases that can be found at a molecular level involving transcriptomics. I would like to know if this microRNAs are going to be useful only for a preventional detection or if in a nearly future this 20-25 nucleotides could be modified not just only to prevent a disease but to eradicate it directly from our DNA. Is this diagnostic capable of use also for another pathologies or is it only for cancer?
@erasmusso
@erasmusso 9 лет назад
I'm curious to see how much does it take for his team and all the research to mysteriously disappear...
@VMKisselev
@VMKisselev 8 лет назад
it's alrady 2016, why, why does it take so long!
@HR-yd5ib
@HR-yd5ib 7 лет назад
because it doesn't work!
@arsenmusulyan7119
@arsenmusulyan7119 6 лет назад
This is a great idea. What is happening with this technology today? This video was done in 2014. Do we have any advances in the last 4 years?
@Deusmecumest
@Deusmecumest 9 лет назад
What a amazing technology. When will it be available to the public worldwide?
@Kasarii
@Kasarii 8 лет назад
+Calo Q. The trick is making a chip that just needs a drop of blood or similar. I worked miRs on my thesis, it's still a good five years away.
@Deusmecumest
@Deusmecumest 8 лет назад
Thank you for the response. Wonderful tech.Kasarii
@fattooh
@fattooh 8 лет назад
عمل عظيم
@emactan
@emactan 9 лет назад
@9:35 he says that the test is accurate. If so what's its sensitivity, specificity and positive predictive value for various types of cancers? And can it distinguish between nonprogressive, gradually progressive, and highly progressive cancers?
@luizmoreira6307
@luizmoreira6307 9 лет назад
dr soto parabéns,por este grande avanco,so espero que aqeles que querem reduzir a populacao nao querem sabotar o seu conjunto,os cumprimentos do mexico por esta descoberta
@comebackata2
@comebackata2 9 лет назад
If it's open source, where can I find it? I can't find it in google right now
@fooruu8946
@fooruu8946 9 лет назад
That's because this, as is often the case in many TED talks, is merely an idea. Vaporware is what it is.
@comebackata2
@comebackata2 9 лет назад
aw ok
@aquabplatsch
@aquabplatsch 9 лет назад
Early cancer detection is an urging issue in todays healthcare and there are still many steps to take. I am curious about the data on sensitivity and specifity of mRNAs. Then I am curious about how he intended to implement the device: There are (blood test) biomarkers available for screening (i.e. PSA for prostate cancer - one of the most common cancer in men, which is quite specific as well). So I ask myself what makes his project a novelty - the easy-to-use approach? The overall-availability? The cloud-networking approach? I wish good success to him and I hope that his projects will be fruitful, heading towards early detection and treatment initiation by doctors.
@brandon2762
@brandon2762 9 лет назад
It is a novel approach because it can supposedly detect any type of cancer with one blood test without having to rely on symptoms or family history for guidance. If this discovery is true, which I have no particular reasons to doubt, it is a revolution in cancer detection.
@Vide0mak3r
@Vide0mak3r 9 лет назад
I would love to know the name of the program he used to show the different types of cancer/diseases and their matching dysfunctional gene expression. Anyone know the name or where I can get my hands on it?
@kwsapphire
@kwsapphire 9 лет назад
Not sure what specific software he used, but look up "mindmap software" and you'll find several versions (many of which are free to use).
@christiansinger2497
@christiansinger2497 9 лет назад
I also would like to know
@toilapumpkin
@toilapumpkin 9 лет назад
you guys can find it here: d3js.org/
@toilapumpkin
@toilapumpkin 9 лет назад
Click on "See more examples" and look up for "Concept network browser".
@christiansinger2497
@christiansinger2497 9 лет назад
Thanks :-)
@Aphetorusbull
@Aphetorusbull 9 лет назад
A lot of the really cool stuff I see on Ted I find is really in the early development stages. This talk makes this look like a slam dunk detection system but conspicuously leaves out how far into the future we'll see this as a common tool used in hospitals. how far off is this to actually being implemented in most working medical facilities? What hurdles are left to gain governmental approval?
@AlimentalElder
@AlimentalElder 9 лет назад
I don't think the main hurdle is government approval. It is finding all the different kinds of micro RNA patterns because there are just so many! Its going to take a year or two or maybe more for this to get going.
@Aphetorusbull
@Aphetorusbull 9 лет назад
ya but we don't need a comprehensive test for all cancers even if it finds only one quickly and inexpensively it should be implemented.
@roidroid
@roidroid 9 лет назад
The test grid is only 8x12, so you only need an 8x12 resolution camera. Any $1 webcam from ebay would do it. It could also just be done in a hand-held device, as tiny as a diabetic's blood sugar monitor.
@finfan7
@finfan7 9 лет назад
Not exactly. Better cameras are more capable of discerning between colours and light levels. It sounds like that would be very important to the results. Using the smartphone, while silly on many levels, also gives a very well defined set of camera capabilities that make careful calibration less necessary. It is clearly possible for them to use less expensive cameras and build a more self contained unit but using smartphones is kind of the big thing right now. They probably just don't have a design engineer on the team.
@Ernestjm2
@Ernestjm2 9 лет назад
As a medical student, I think this can easily have a profound impact on patients. Although it seems simple enough, there are so so many complexities involved with this research, and I think we're still at least a decade out of reach for its practical use. He says it's sensitive, but how specific is it? Just because a test can detect all cancer doesn't mean it should be used. There are problems with false positives as well, since they can cause unnecessary harm in the form of added stress, unnecessary procedures and treatment. I do think tests like this are the future, and I hope it comes sooner than I think it will.
@glamdrag
@glamdrag 9 лет назад
Im sure that when cancer gets detected this way, there would be a follow up examination. They're not just blindly going to cut people open. If it can detect cancer in 90% of people who have cancer, but detects another 20% extra in people who don't have cancer, it's still a good way of detecting it early. It doesn't mean that the 20% who don't have cancer are going to get cancer treatment immediately.
@weisong8666
@weisong8666 5 лет назад
He is so altruistic to make this great innovation open source.
@sambarker6141
@sambarker6141 9 лет назад
Amazing presentation, but he didn't really explain exactly how the device works, I'd love to know that.
@RSP13
@RSP13 9 лет назад
Me too, but it will be open source. We'll be able to read all the project data.
@sambarker6141
@sambarker6141 9 лет назад
RenanzinhoSP Sweet.
@roidroid
@roidroid 9 лет назад
He's looking at the types of MicroRNA (miRNA) in the blood. It's kindof like searching through the local landfill, analyzing people's thrown-out paperwork and reciepts, to get an idea of how many people are (for example) actively committing tax fraud. Every activity has a specific signature. If you find a lot of receipts for paints and paper, you may conclude that there's a lot of artists in the area. If you find a lot of receipts for bullets and bombs, maybe you've got a military situation on your hands. MicroRNA is like the thrown-out paperwork. By analyzing it, you can figure out what the cells in the body are doing. Different types of cells emit specific signatures or patterns of MicroRNA, and cells with cancer also have specific signatures. The various vials in his device each contain a unique mix of chemicals which only react with specific types of MicroRNA, if you add that MicroRNA into the vial it will glow, how fast and how bright it glows can tell you how much of the MicroRNA is in the vial. The camera then looks at the vials, in a controlled lighting environment (that's why it's in a closed box). This allows the speed and brightness information of the vials to be converted into simple data, which can be graphed. The graph is like a signature, which tells you if you have cancer, and what type it is. Over time, we'll discover more signatures, and be able to identify more cancers.
@lyriclanguages3780
@lyriclanguages3780 9 лет назад
Maybe it was the time limit?
@sambarker6141
@sambarker6141 9 лет назад
Nyx Gypsy That's what I'm guessing, it's a complicated subject haha. But I've been getting some very helpful responses to my original comment, so I think I understand how it works now.
@pauloliversa2009
@pauloliversa2009 8 лет назад
100%
@MrsBlove
@MrsBlove 9 лет назад
How can we help?
@slhines7
@slhines7 9 лет назад
This simple, noninvasive, and awesome open-source test in combination using CBD's and other alternative treatments would ultimately be ideal, as opposed to the mostly expensive and unsuccessful radiation and chemo.
@Liberty309
@Liberty309 5 лет назад
Has probably been bought and shelved by now. Haven't heard any more about this since this video was made !!!
@dalidabadawi94
@dalidabadawi94 7 лет назад
Is Tony Montana giving this TED Talk? #nohate
@CyberiusT
@CyberiusT 9 лет назад
Deserving of a Nobel for Medicine, imho. Probably won't get one while anyone involved is still alive, though.
@pedrosuarez4528
@pedrosuarez4528 9 лет назад
Detection democratise its cool, just try to share you info of the clouds with many other places. NSA and big pharma corp may trash your ideal approach. Remember cancer treatment is a huge business.
@piyushnarayan8137
@piyushnarayan8137 5 лет назад
Cancer detection is a multi-stage process. Once in a while cancer is found by chance but most of the time from screening. The final stage of cancer diagnosis depends on an Oncologist's(it is a branch of medicine that deals with the prevention, diagnosis, and treatment of cancer) judgment. On the contrary, if it's speculated that you have cancer, the doctor may prescribe certain "cancer blood tests" or other "lab tests", for example, an investigation of your urine or a biopsy of a suspicious area where cancer is speculated. Read More: www.allin122.com/2018/10/cancer-detection-and-treatment.html
@Ajs00
@Ajs00 9 лет назад
Early cancer detection or diagnoses has no relation to mortality rate. Number one rule in epidemiology. But interesting video.
@disastergirl888
@disastergirl888 9 лет назад
Really? Do you have any sources for that? That's quite a surprising claim, given that early stages of cancer often haven't metastasised so can be treated far more effectively, not just with surgery but also molecular treatments (such as inhibition of autophagy and apoptosis) that aren't effective in later stages of cancer.
@Ajs00
@Ajs00 9 лет назад
I read it in my medical textbook a while ago. Here is an article that may provide some information. www.score95.com/blog/blog/usmle-trends-in-cancer-incidence-and-mortality/ But yeah early detection of cancer will not decrease mortality rate. Especially if the cancer cell has reached Anaplasia, It is not reversible and quite abnormal at this point.
@markmusatau1929
@markmusatau1929 8 лет назад
+Ajs00 Did you contradict your self? At this point? Mortality rate for all is 100% but when is key. So no, time does play a huge role.
@AnimeshSharma1977
@AnimeshSharma1977 9 лет назад
microRNA expression pattern recognition and correlation with existing published literature in the cloud, this is indeed miroculus ;)
@MalignSociety
@MalignSociety 9 лет назад
How do videos of Kardashians have millions of views but a video of early cancer detection only 50k. Man on man our societies priorities...
@pnkflyd66
@pnkflyd66 6 лет назад
People are f’kin stupid.
@avc9103
@avc9103 9 лет назад
I really get what it's like to see someone stating their opinion or belief that completely opposes your own. The truth is there is no point in commenting back and I did, for a long time, even while I knew, completely and consciously it wouldn't amount to anything. So here's something to make your lives easier; don't comment against people, comment for people or for yourself. And something for the atheists specifically. One day the universe will just end and therefore nothing will ever matter. Ever.
@adsglobal3351
@adsglobal3351 9 лет назад
Who on earth thumbs down this? Let me guess...you don't like that he uses an iPhone?
@soinlove8306
@soinlove8306 7 лет назад
lol I have accidentally thumb things down but if anything it would be someone making a lot off of cancer patients.
@minimaxhall
@minimaxhall 9 лет назад
Is it me or is patent/copyright taking a U-turn here? :D
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