The Metabolism of Female Infertility with Dr. Ben Bikman

Подписаться 52 тыс.

Просмотров 9 тыс.

50% 1

In this lecture, Professor Ben Bikman delves into the metabolic aspects of female infertility, specifically focusing on the influence of insulin resistance. He begins by highlighting the high prevalence of infertility among women of reproductive age, with up to 15% affected globally, and particularly prevalent in regions with high rates of insulin resistance, such as Sub-Saharan Africa, South Asia, and the Middle East.
Insulin resistance, a condition where cells become less responsive to insulin, plays a crucial role in female infertility. Dr. Bikman explains that insulin resistance manifests in two main aspects: disrupted insulin signaling in cells and elevated blood insulin levels, known as hyperinsulinemia. These disruptions affect various stages of reproductive physiology, including oocyte development, ovulation, and implantation.
Dr. Bikman then provides a detailed explanation of the ovulatory cycle, emphasizing the interplay of hormones such as follicle-stimulating hormone (FSH), estradiol, and luteinizing hormone (LH) in regulating follicle growth, ovulation, and corpus luteum formation. He discusses how insulin resistance can interfere with this process, leading to poor oocyte quality, failed ovulation, and complications with implantation.
The lecture further explores conditions associated with insulin resistance and female infertility, notably polycystic ovary syndrome (PCOS). Dr. Bikman explains the Rotterdam criteria used for diagnosing PCOS, which include irregular ovulation, signs of hyperandrogenism, and ovarian cysts. He elucidates how insulin resistance contributes to the development of PCOS by inhibiting aromatase activity, leading to reduced estradiol production and disrupted ovulation.
Finally, Dr. Bikman discusses treatment approaches for PCOS, including the use of insulin-sensitizing medications like metformin and dietary interventions such as low-carbohydrate or ketogenic diets. He underscores the importance of addressing insulin resistance to improve ovulatory function and mitigate the most common form of female infertility.
(00:01) Introduction to Female Infertility and Metabolism
(01:14) Global Prevalence of Female Infertility and its Association with Insulin Resistance
(02:23) Understanding Insulin Resistance and its Impact on Female Reproductive Physiology
(05:30) The Ovulatory Cycle and the Role of Hormones in Reproduction
(11:14) Effects of Insulin Resistance on Oocyte Development and Ovulation
(13:27) Impact of Insulin Resistance on Implantation and Uterine Health
(17:19) Polycystic Ovary Syndrome (PCOS) and its Relationship with Insulin Resistance
(33:44) Treatment Approaches for PCOS: Medications and Dietary Interventions
Learn more at www.insuliniq.com
#pcos #pcosawareness #PCOSTips #PCOSJourney #PCOSCommunity #PCOSFight #PCOSWarrior #FertilityJourney #InfertilityAwareness #TTC #FertilityTips #FertilitySupport #InfertilitySupport #ConceptionJourney #FertilityTreatment #PCOSandFertility #InfertilityStruggle #PCOSAwarenessMonth #IVF #FertilityHealth #FertilitySuccessStories

Наука

Опубликовано:

9 апр 2024

Ссылка:

Скачать:

Готовим ссылку...

Добавить в:

Мой плейлист

Посмотреть позже

Комментарии : 25

@fronniebealer7808 2 месяца назад

The old saying: times flies when you are having fun seems to apply to Prof. Bikman's lectures. These lectures are so easy to listen to and assimilate.

@PrevMedHealth 2 месяца назад

I appreciate your clarity on metabolic diseases like High BP, headache, infertility, etc.

@JasonBuckman 2 месяца назад

It's all the same disease. Those are the symptoms.

@m.esmeraldacaceres3171 2 месяца назад

@@JasonBuckman I'm pretty sure Dr. Ford Brewer knows pretty well what they are. Just check his RU-vid channel out...

@amyrevis9239 2 месяца назад

I just wanted to thank you so much giving us all this information every week.

@HormoneRx 2 месяца назад

you explain that so well, I am so happy to have found your lecture series.

@silvadoll3370 2 месяца назад

Im the classic example of skinny pcos , thank you for this explanation and the research, i can finally get on top of this condition by getting insulin lower

@TagiukGold 2 месяца назад

I really appreciate the precise language carefully using the most accurately appropriate words available.

@kimduyennguyen5433 2 месяца назад

Thank you Dr. Ben Biikman ❤

@Hertz2laugh 2 месяца назад

Would be great if the studies referenced by Dr. Bikman were linked in the video description.

@AlyssaWolverton 2 месяца назад

Thabks for sharing! I am currently a surrogate and they told me the wait for surrogates used to to 2 or 3 months and now its a year and half. Basically due to decreased health of women having kids and decreased health of applicable women (normal BMI, low fibroids). It is really wild. Thanks for sharing the info!

@-zeina-8008 2 месяца назад

God bless you for your work and sharing your knowledge -- it is _greatly_ appreciated! & thank you for trying to explain science in the most layman terms possible, but I am not that smart and will definitely (and gladly) have to re-listen!!

@user-xu1df3cy8r 2 месяца назад

Прекрасное и понятное изложение темы. Бен, как повезло твоим студентам учиться у тебя. 😊❤

@alibee102 2 месяца назад

Would it be safe to assume that it's a similar story for endometriosis?

@judew939 9 дней назад

Ok. So yes i did have very painful periods. No children. Drs who prescribed me contraceptives for it (without my knowledge of what they really were) 🤨 this is now making sense.

@Tee667 2 месяца назад

Adipose IR for the 20% that appear to have normal blood fasting insulin and normal weight. It’s NOT fat mass in all circumstances but fat cell size (that are hypotrophic and insulin resistant) that determine metabolic health, causing elevated free fatty acids. Measuring insulin resistance at the level of the fat cell. His favourite blood - test free fatty acids and blood fasting insulin, multiply these two tests. Metformin EVEN when insulin resistance has not been confirmed is prescribed for insulin sensitivity to take place. Ketogenic Diet also for insulin sensitivity. YOH I hope I heard that correctly.

@victoriashi5680 2 месяца назад

Thank you. I am concerned about teen daughter who's doctor wanted to pit her on hormonal monthly pills but did mention that metformin is another route. The only hormone out of balance is testosterone (60). But she doesn't have other pcos symptoms (slim, no acne, hair is good, but skip periods when stressed in school). I sm against unnecessary pills especially if that don't cure anything. Your video made me realize we need to do sonogram of ovaries. And possibly do keto. I am myself on keto (dr Mindy Pelz style, and regularly fasting). My daughter sees me benefiting from this and it will be easy transition for her. Is 17 y.o. ok to do intermittent fasting? Or should we wait till she is 18? Thank you!

@insuliniq 2 месяца назад

Thanks for your question. You may want to go to our website and ask my team: www.insuliniq.com

@steffendudley8214 Месяц назад

Dr.Anthony Chaffee😊

@-zeina-8008 2 месяца назад

🤦🏻‍♀️ It's like you're describing _me!!_ 🙈🙈

@sanketchavan9456 Месяц назад

Can someone pls state the other strategies to correct PCOS....

@insuliniq Месяц назад

Thanks for your comment. If you are struggling with PCOS, you may find value through group coaching and engagement with like-minded people working on their metabolic health in our Insulin IQ community: www.insuliniq.com/insulin-iq-community-membership-signup

@annesummers09 2 месяца назад

I have a strange issue with insulin. My fasting insulin is around 20. For decades at the time of day, 4-6pm, I fall asleep. No matter if I eat high carb, low carb or nothing at all. I fall asleep sitting in my chair or I become so sleepy I cannot function, I have to sit down and then I pass out. I can't seem to stop it. I usually ate at that time through the years as I worked the 3-11 shift at the hospital. Should I skip that time of day to eat or should I eat at that time since my insulin levels are obviously already high? I think my insulin levels must be surging at that time so that is why I go into sleep-coma at that time. It really feels more like I slip into a coma for an hour than it being just regular sleep. How should I handle that. I mentioned it to my Dr. who said "Hmmm, I don't know." That was it. (My Dr. is just 3 years out of med school-age 32-very sweet, tho) He doesn't consider fasting insulin important at all. I had to INSIST on a fasting insulin level being done. I wish you were my Dr. Thanks for the videos and info.