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This Protein Hugs Ice Crystals to Death 

Clockwork
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If liquid water is an absolute requirement for life--how on earth does ANYTHING survive in Earth's polar regions? What should be a frozen wasteland is a thriving ecosystem. Let's look at ice structuring proteins and discover how they literally bind to ice crystals as they form--giving the smallest arctic critters a fighting chance.
Sources and supplementary materials in this ever-growing twitter thread: / 1362432741531283458
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Support the channel directly with a one time donation: www.paypal.me/clockworkshow
Deep sea footage by NOAA:oceanexplorer.noaa.gov/video_...
All music is by Jeremy Blake( / redmeansrecording , released on the RU-vid Audio Library.
Intro music: Let's Go Home (bit.ly/rmrlgh)
Outro music: Lost and Found (bit.ly/rmrlnf)
The style of this video was largely developed based on tutorials by Ben Marriot: (bit.ly/posterizethis)
Support Clockwork through our affiliate links: sovrn.co/crbe0ll

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17 фев 2021

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Комментарии : 104   
@sriramramesh5318
@sriramramesh5318 3 года назад
It's weird thinking of how the hydrophobic side of these proteins are probably making the proteins spin around nonstop whenever the temperature is anywhere above freezing
@Clockworkbio
@Clockworkbio 3 года назад
It could be that they aren't made until an organism hits a certain temperature too. Lots of factors here the research is still figuring out!
@zlodevil426
@zlodevil426 Месяц назад
There could be quintillions of molecules in your body right now that just spin and don’t do anything else
@ALTERRAa8
@ALTERRAa8 Месяц назад
​@@zlodevil426 reletable
@casualbird7671
@casualbird7671 29 дней назад
​@@zlodevil426 Like the compliment system~
@Antleredangelbun
@Antleredangelbun 29 дней назад
My brain's reward system lol​@@zlodevil426
@thegoodlydragon7452
@thegoodlydragon7452 3 года назад
"Kill it to death." lol
@hingsunhome
@hingsunhome 21 день назад
The floor is made of floor
@kalmanchrister1027
@kalmanchrister1027 3 года назад
Another interesting protein is kind of the reverse of this one: ice nucleating proteins. They seem to help form ice crystals by providing a kind of optimal scaffolding for water molecules, so that they will bind together. They may have a role in ice nucleation in clouds, and by extension, formation of rain and global water cycles!
@Clockworkbio
@Clockworkbio 3 года назад
Welp. I didn't have a _lot_ of time for a research hole--but here we are!
@bladdnun3016
@bladdnun3016 27 дней назад
How do the nucleating proteins get into a cloud? And why would an organism want ice to form? To use the enthalpy of fusion to keep warm?
@Avaney69005
@Avaney69005 27 дней назад
Your video is good​@@Clockworkbio
@john-ic5pz
@john-ic5pz 25 дней назад
@bladdnun3016 ikr. I call b.s. on this. atmospheric dust isn't an effective nucleation site?
@MrSaliVader
@MrSaliVader 24 дня назад
@@john-ic5pz It is, but ice nucleating proteins are even better
@IncidentallyHuman
@IncidentallyHuman 3 года назад
Hopefully this channel blows up in popularity. It deserves it.
@petervansan1054
@petervansan1054 9 месяцев назад
shame it died :(
@taoafro1740
@taoafro1740 Месяц назад
I agree. ✌🏾❤️
@1337bitcoin
@1337bitcoin 29 дней назад
2024 finally getting the recognition this channel deserves
@CanOSpamX
@CanOSpamX 3 года назад
Great video! I've seen tons of videos here on RU-vid talking about how "fish have antifreeze in their blood" but as far as I know no one has actually talked about how that really works and boy is it fascinating. This channel makes we wish I took more bioscience courses. :)
@mmcharchuta
@mmcharchuta 3 года назад
Your graphics are amazing and your loose style makes the learning process all the more fun. I feel like i'm listening to a friend :D
@arofhoof
@arofhoof 24 дня назад
Such an incredibly high quality channel, it should have millions subscribers! Fantastic!
@brianrubin2069
@brianrubin2069 3 года назад
"kill it to death" the most scientific of terms. Great video! Hope more people start watching you soon! Also did your website go down where you had the more in-depth explanations?
@Clockworkbio
@Clockworkbio 3 года назад
Yea I had to shutter the in-depth explanations for now! When you're a small youtuber--the budget is real tight. I decided to crowdsource the details/ disucssion on my twitter (@this_clockwork) and use the website budget to fact check my bigger scripts for now. This one didn't make the cut for fact checking since I needed that whole budget to make sure I nail the facts for my March video. There are some really interesting wrinkles in what make these proteins work tho!
@brianrubin2069
@brianrubin2069 3 года назад
@@Clockworkbio Makes sense! Good luck with production!
@noel.gonsalves
@noel.gonsalves 3 года назад
This legitimately blew my mind. I did not see that coming.
@Clockworkbio
@Clockworkbio 3 года назад
Biochem is so nuts, right?
@noel.gonsalves
@noel.gonsalves 3 года назад
@@Clockworkbio indeed it is
@bioZone101
@bioZone101 3 года назад
getting hugged to death ain't sounding half bad anymore
@Clockworkbio
@Clockworkbio 3 года назад
I mean, of all the ways to go, right?
@justenkem5514
@justenkem5514 Год назад
"Your test results came back aladine" "is that aladine or aladine" "it is aladine" 😅😳🥺😅🥺
@Information_Seeker
@Information_Seeker Месяц назад
so cryosleep is back on the table?
@nickcooper8995
@nickcooper8995 22 дня назад
It seem so, with these we could freze only some specific organs
@adityasingh-yz7tr
@adityasingh-yz7tr Месяц назад
Absolutely great video . i hope the algorithm gives you the reach you deserve even if it's 3 year late
@cassidyhawk420
@cassidyhawk420 3 года назад
Marine biology student here, great video!
@sethsoarenson7414
@sethsoarenson7414 3 года назад
Texans: WRITE THAT DOWN! WRITE THAT DOWN!
@somethingsafoot
@somethingsafoot 3 года назад
biocord represent great video
@rosemarychadi7734
@rosemarychadi7734 3 года назад
Great video! we really enjoyed it
@AaronQuitta
@AaronQuitta 3 года назад
Crazy, amazing, I love this! Thanks for the great video.
@ItsGray3
@ItsGray3 Месяц назад
This channel has such amazing videos and deserves way more attention than it currently has!
@arrowinmygluteusmaximus
@arrowinmygluteusmaximus 3 года назад
any tips for a fellow creator? you seem to be able to crank these videos out at an incredible pace, even though they are so heavily edited and high quality while simultaneously being so small (in number of subscribers) that I'm assuming you don't do this full time.
@Unraveled
@Unraveled 3 года назад
He's awesome like that
@AntonWongVideo
@AntonWongVideo 3 года назад
I'm guessing planning and scheduling helps a lot with that!
@arrowinmygluteusmaximus
@arrowinmygluteusmaximus 3 года назад
but wouldn't this just delay ice forming not lower the temperature required to freeze? as long as there is liquid water below the freezing point a new nucleation point can start right? or do these structures also slowly melt the ice they surround?
@Lacksi12
@Lacksi12 3 года назад
Came here to ask exactly this aswell. If anyone knows the answer Im interested to hear it!
@AaronQuitta
@AaronQuitta 3 года назад
Maybe its the temperature foe an entire body of water to freeze?
@silverharloe
@silverharloe 3 года назад
they delay ice forming, as you say. and then water starts to crystalize somewhere else and gets delayed... and after a few iterations of that, you're delaying it so much that it's not freezing. but if you go colder, then the crystallization goes faster than the delays -- that colder point is the new(lower) freezing temperature. freezing is an average - you take a quintillion water molecules which are all jiggling around and slow a bunch of them down and that's what colder water means - less jiggling overall, but the jiggling hasn't stopped. keep slowing a bunch down (i.e. lower the temperature) and eventually some are so slow they start to hang together more than they jiggle apart. but they are still being jostled by nearby jiggling molecules, pushing them apart as they try to hang together. bits of ice are forming and breaking constantly as the temperature lowers - delaying the formation of crystals is the same as lowering the freezing point, because you need the crystals to start forming faster than they are being broken by nearby jiggling water molecules -- which is to say you need to slow down the nearby water molecules (also known as lowering the temperature) so they are more likely to join in the crystal than to knock it apart. I need some of this guy's animation skills, but hopefully you get the idea anyway.
@silverharloe
@silverharloe 3 года назад
Now I'm envisioning a dance club full of people all bumping into each other as they dance - and some people try to slow dance, but with all the bumping they keep getting bumped apart. some people get tired and start dancing slower, but there's not a DJ that tells everyone to stop and find a partner all at the same time. because the DJ isn't there to tell everyone to be cold all at once, it takes a long time for everyone to get tired enough that more and more slow dances can come together without being bumped apart. in addition to what I said about freezing being an average - the other important thing is that freezing is the default state. the water doesn't GET slowed down, it's slowing down all on it own. "making it colder" is a process of "adding less and less heat" and letting the heat it bleed off. but absolute zero is very difficult to achieve - so you're never really adding zero heat, just less heat. you can add so little that you aren't making up for heat that is going away - we call that the freezing point, but you still need some time to let all the heat drain out for it to actually finish freezing. I'm trying here, but even "freezing water" is complicated stuff. Sorry if I'm not properly explaining it.
@person8064
@person8064 14 дней назад
​@@silverharloe So, basically, at tiny scales ice likes to spontaneously decompose, and by delaying its rate of formation you keep the ice decomposing faster than it can form.
@brahimbest1
@brahimbest1 3 года назад
Really, that blows my mind!
@Alexadria205
@Alexadria205 Месяц назад
I can see crops being genetically engineered to produce these proteins to create frost resistant crops!
@Lars_Maassen
@Lars_Maassen 3 года назад
3:09 Hexagon is bestagon
@Clockworkbio
@Clockworkbio 3 года назад
It really is! And there're EVERYWHERE in biochem and Organic Chemistry!
@AntonWongVideo
@AntonWongVideo 3 года назад
1:16 plankton are VERY important for the food chain...just not for the Krusty Krab Also, I'm digging this "stop motion" mograph animation style! How many times did you use "wiggle" expressions in After Effects?
@xavierestelles9327
@xavierestelles9327 3 года назад
This is FASCINATING
@Unraveled
@Unraveled 3 года назад
Someone stole my "hexagons are the bestagons" comment so now I don't know what to say...
@thesmallcheval
@thesmallcheval 23 дня назад
Holy $hit that is wild to learn. I love this channel!
@LFTRnow
@LFTRnow 26 дней назад
This is not my specialty but as an engineer, i love these vids. You can just watch the chemistry and mechanical features in action, and in fairly short vids too!
@this_1_dude_named_iggy654
@this_1_dude_named_iggy654 28 дней назад
How am i not gonna immediately click this video with information as cool as this
@jujjuj7676
@jujjuj7676 Месяц назад
Make more please!!! More biochem!!!😊😊😊😊
@jesusvalencia5520
@jesusvalencia5520 2 месяца назад
Great video!! I have a question. I read that inside the Beta sheets, the Threonine aminoacid was the one binding to the ice crystals. Maybe a different protein in the same family?
@defeatSpace
@defeatSpace 25 дней назад
Phenomenal videos 😁
@agnosticmuslim6341
@agnosticmuslim6341 Месяц назад
Loveee Biochem when taught like this
@beastypie99
@beastypie99 3 года назад
Very cool!
@Clockworkbio
@Clockworkbio 3 года назад
thanks so much!
@MrAngelos006
@MrAngelos006 3 года назад
first video and I'm amazed
@MrAngelos006
@MrAngelos006 3 года назад
gonna watch and like all your videos
@lauradftba4653
@lauradftba4653 3 года назад
This is so cool!!!!
@Clockworkbio
@Clockworkbio 3 года назад
NO YOU
@diakritika
@diakritika 24 дня назад
The million dollar question is: can it work in reverse? I.e., turning a solid block of ice back into microsopic ice crystals?
@cykonot
@cykonot 25 дней назад
i like that your proteins jiggle
@hoteny
@hoteny 24 дня назад
Time to freeze ourselves then
@noekiyu
@noekiyu 3 года назад
You really sound like Jim Parsons from the Big Bang Theory.
@quantumview8151
@quantumview8151 Месяц назад
What happens then. Wouldnt enough clumps eventually take over enough area that the cell cant function, or do they expell it or destroy it in some way?
@zeroTorsion
@zeroTorsion 28 дней назад
love it
@pimbel8830
@pimbel8830 Месяц назад
This video isn't part of any playlist so it will be kinda hard to find
@realkekz
@realkekz Месяц назад
Please come back
@Clockworkbio
@Clockworkbio Месяц назад
ONE MORE MONTH
@realkekz
@realkekz Месяц назад
@@Clockworkbio :) I found this channel at the exact right time!
@deliyomgam7382
@deliyomgam7382 22 дня назад
How to freeze carbon to graphene?
@ToniMorton
@ToniMorton 22 дня назад
wait could this protein be used in humans or is it toxic/immune detected? cryonics??
@vinniepeterss
@vinniepeterss 26 дней назад
❤❤
@KitsuAwA
@KitsuAwA 27 дней назад
Dumb instrusive thought,could a human consume this to last longer in cold envs
@jabu5427
@jabu5427 3 года назад
Water life
@Clockworkbio
@Clockworkbio 3 года назад
and a little sunlight and some air and a couple minerals!
@particleonazock2246
@particleonazock2246 2 года назад
Meanie protein
@deliyomgam7382
@deliyomgam7382 22 дня назад
Nano bots?
@matteomezzetti8277
@matteomezzetti8277 Месяц назад
I love this channel but its dead😢
@matteomezzetti8277
@matteomezzetti8277 Месяц назад
NEVERMIND SEASON 2 JUNE
@3glitch9
@3glitch9 26 дней назад
Stay squishy my friends...
@Clockworkbio
@Clockworkbio 26 дней назад
brb stealing this line
@sheldondrake8935
@sheldondrake8935 Месяц назад
great content, should have a ton more subs...but the vocal fry is unbearable...
@johnacetable7201
@johnacetable7201 24 дня назад
The science is somewhat alright in this video, but I suggest you to use less jargon, and unnecessary words such as "process" in sentences like "the election process was rigged" first off, you come across as snobish, second it doesn't gell at all with you using "casual" slang; thirdly in this circumstance it doesn't enhance the communication _process_ , but cripples it.
@saddish2816
@saddish2816 24 дня назад
jfl
@michaelshea4834
@michaelshea4834 Год назад
I’ve always been annoyed by people who ascribe intelligence to an inanimate (evolution) process. It’s an argument for God.
@kventinho
@kventinho 22 дня назад
who says "al-a-NINE"? It's 'al-a-NEEN'!! It's vaLEEN not vaLINE, it's threoNEEN not threoNINE, it's pronounced glootaMEEN, not gloota-MINE!!!! This annoys me so much! You are a biochem channel, get it right!!!
@ekbergiw
@ekbergiw Год назад
2:48 shout-out to @viheart
@john-ic5pz
@john-ic5pz 25 дней назад
wth...I've never heard alanine pronounced that way is glycine /gly - sine/ too?
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