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Transport inside the brain: The basic mechanisms of neuronal trafficking 

Hoogenraad Lab
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The primary aim of the Hoogenraad research lab at the University of Utrecht, the Netherlands, is to understand how intracellular transport underlies the development and function of nerve cells. During this animation, we will follow a presynaptic cargo during its journey through a nerve cell, illustrating the basic mechanisms, regulation and relevance of proper intracellular transport that occurs inside the cells of our brain.
cellbiology.sci...
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Permission to use this video is not required. When you use our materials in print, on the Web or in a video or audio format, we simply request that you credit the "Hoogenraad lab at the Utrecht University" and refer to our website at cellbiology.sci...

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27 сен 2024

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Комментарии : 162   
@revenger211
@revenger211 Год назад
Actually insane. I'm learning neuroscience at the moment for the fun of it and wanted to actually see how it looks because I couldn't imagine it and oh boy this way crazier than I had imagined!
@Cozy.Mood.B
@Cozy.Mood.B Год назад
This is endlessly incredible. I have no words. Nature is out of this world!
@deadly.desai2
@deadly.desai2 4 года назад
its only 1% related to my Studies, but damn! i just enjoyed watching the animation
@miramardream
@miramardream 5 лет назад
Wow, that trailer was amazing. When's the movie coming out?
@caseyalakwa5263
@caseyalakwa5263 4 года назад
Hahaha
@quinattasneemrafique536
@quinattasneemrafique536 3 года назад
Really want one movie on cell🥺
@ThomasConover
@ThomasConover 2 года назад
YOU are the movie bro.
@Rosenthal-z7x
@Rosenthal-z7x Год назад
I can sign now or you can wait till dead I me technically the gov marked me dead already 🎉
@Rosenthal-z7x
@Rosenthal-z7x Год назад
I dont mind
@Neurosoul22.0
@Neurosoul22.0 7 лет назад
Dear Hoogenraad lab, thank you indebtedly for this animation - it is one of the most superb renditions of sci animation ive encountered... could i ask how the graphics were constructed/what software/which company etc.? Im a neuro graduate interested in getting into scie animating myself Many thanks!
@phebewulf9722
@phebewulf9722 3 года назад
That info is at the end of the movie.
@quinattasneemrafique536
@quinattasneemrafique536 3 года назад
@@phebewulf9722 I wasn't there😟
@Nonamelol.
@Nonamelol. 6 месяцев назад
How exactly though does that entire process give me this experience??
@goldengaming4911
@goldengaming4911 7 лет назад
Omg the 3D animation
@bindasskanya3509
@bindasskanya3509 3 года назад
I m an accountant but I m enjoying watching it, Beautiful
@anonymousplayer6378
@anonymousplayer6378 2 года назад
Really a wonderful animation for a difficult topic to teach.
@mshisha
@mshisha 8 лет назад
Great animation
@tonioverton9
@tonioverton9 7 лет назад
INCREDIBLE!!! Learning can be fun and interesting as well as educational. Thank you very much.
@ИванШепелев-м2ъ
@ИванШепелев-м2ъ 7 месяцев назад
Классно , молодцы. Побольше бы таких интересных видео.
@meghapaul9013
@meghapaul9013 4 месяца назад
They behave like ants. Fighting for a cargo to take it according to their direction. 😂
@crislin830
@crislin830 11 дней назад
Sou do Brasil. Esse video tem 9 anos e ainda assim são os melhores videos🤩🥰👏🏾👏🏾🎉 Pena que são apenas em inglês 😢
@CurtisLongkeep-uu3sm
@CurtisLongkeep-uu3sm 7 месяцев назад
This was very fascinating to watch. Thank you for the upload. 10/10.
@paulaojala177
@paulaojala177 4 месяца назад
Makes me want delve even deeper into this cellular and molecular world!🤩
@tanveerasarhadi8872
@tanveerasarhadi8872 2 года назад
Never have I ever tripped so bad on an educational video before
@santrolli
@santrolli 2 года назад
Awesome visualisation! Thank you 🙏
@Ta3allamOnline
@Ta3allamOnline 6 лет назад
An Amazing video!
@rossanaperrone3611
@rossanaperrone3611 2 года назад
Hello! Thanks for this amazing video. I am a neuroscientist and a teacher in the School of Psychology in Uruguay. Can I use this video for teaching? Thank you very much.
@hilan0_767
@hilan0_767 Месяц назад
Sure i guess
@Dr.Zubair
@Dr.Zubair Год назад
Exactly what i was searching for
@chizauz
@chizauz 2 года назад
Ignore my previous comments and questions. I just watched a day in the life of John the walking motor protein. thanks for the video
@abdulirhouma911
@abdulirhouma911 4 года назад
3:26 yeeeeeet
@BritishGamerChick
@BritishGamerChick 11 месяцев назад
I get so excited watching this stuff. I'm like a kid in a sweet shop. 😂😊
@TheMraaqib
@TheMraaqib 3 года назад
How Great the Creator would be. 🤯
@AsiPtl
@AsiPtl 5 месяцев назад
ASTONISHING!!
@Queen-fq4nk
@Queen-fq4nk 5 месяцев назад
Lil bro is really strong
@gosangel
@gosangel 8 лет назад
Buenos días, me gustaría saber si ustedes podrían subtitular todos los videos de este magnífico canal, pensando en las personas que NO hablamos inglés o poco lo entendemos. Gracias por su atención!!!
@ahntrjmpr
@ahntrjmpr 6 лет назад
Yo podria hacerlo si lo necesiten!!!
@36yovan
@36yovan 4 года назад
*Through the 3D animation video we are able to understand a little bit how marvelously and wonderfully we are formed in our mother's womb by our Creator ! Praise be to God 🙏*
@ellios5734
@ellios5734 2 года назад
Please upload more videos your animations are the best
@entisarnasser265
@entisarnasser265 4 года назад
Why u are stop posting video ?? your video is too useful
@michaelb1785
@michaelb1785 6 лет назад
What is the role of sleep and regulation of micro-tubules?
@aaronj7081
@aaronj7081 7 лет назад
"The human brain, one of our most complex organs" Our most complex organ. The most complex organ in the animal kingdom. Why undermine the feat of understanding from the start, but ok.
@codyharrison771
@codyharrison771 4 года назад
I've hear people say it's the most complex object in the known universe
@anemari5809
@anemari5809 3 года назад
It's like a suspense/thriller movie hahaha
@jamesl1014
@jamesl1014 2 года назад
Intro song is Renascentiae, Sexually Assault. That is, some rendition of it I'd love to find an extended mix of- Hoogenrad sound persons I hope you're listening. 🙃
@Nbokar
@Nbokar 6 лет назад
Need more videos
@vehicleboi5598
@vehicleboi5598 2 года назад
realistic john
@bryzvyy1674
@bryzvyy1674 3 года назад
This is one of the most Biopunk I have ever seen in my entire life.
@yina125
@yina125 Год назад
How incredible it is!!!❤
@kikithepupper6774
@kikithepupper6774 4 года назад
This is so beautiful.... WHo made this animation?
@vitus008
@vitus008 8 лет назад
awesome video ....!!
@ridhima035
@ridhima035 19 дней назад
amazing💥
@siddharthannandhakumar6187
@siddharthannandhakumar6187 3 года назад
Do the motor proteins really transport like walking?
@flory6901
@flory6901 2 года назад
Yes this protein called Kinesin walks 250 steps per second
@flory6901
@flory6901 2 года назад
If something goes wrong and there is traffic of this protein, it results in Brain Disease
@paftaf
@paftaf 5 лет назад
Thanks!
@melissamiller8063
@melissamiller8063 2 года назад
It is the universe inside.
@jinanarzary5677
@jinanarzary5677 5 лет назад
Wow!!
@checkpointame
@checkpointame 7 лет назад
Hey we are making a school project about social media and how it affects the brain. Can I use short clips from your video to support the meaning? Looks amazing!
@ifhtfilms
@ifhtfilms 7 лет назад
I'm only here for the shooting star meme loop
@markshilhavy8326
@markshilhavy8326 2 года назад
Brain diseases like what, I wonder. I've had several small brain injuries, one that left me unconscious for several minutes. Is depression or anxiety considered brain disease, I wonder. Cool video
@ninjatiger1163
@ninjatiger1163 4 года назад
hey what is the name of the mucis when it transistion into the brain 0:19
@petercareer439
@petercareer439 6 лет назад
Have you ever done a video of how estrogen receptor positive cancer cells find and feed off of the over produced estrogen in a man or a woman’s body?
@سجلأنامسلم
@سجلأنامسلم 2 года назад
سبحان الله العظيم ، كل من يقول لك أن كل هذا أتى بالعشوائية والصدفة فقط إضحك
@ahmedtzaki4476
@ahmedtzaki4476 Год назад
AMAZING! It's very mind-blowing that reality is even more beautiful and complex and much faster than this! It's also unbelievable how there still atheists in the 21th century after all of these discoveries!
@sulimansal2990
@sulimansal2990 3 года назад
الله هو المهندس الأعظم.
@markopolofan5652
@markopolofan5652 4 года назад
omg so cool
@hajnalkakoller31
@hajnalkakoller31 3 года назад
Danke GOTT
@DjDiDAS
@DjDiDAS 3 года назад
Damn... definitely need to watch this on mushrooms or LSD trippie as FAh-Q! lol
@protoborg
@protoborg 6 лет назад
Imagine if you managed to hack even a single neuron. The human brain is sooooo easy to hack if you control even just a few dozen neurons.
@kellogscornflakes2430
@kellogscornflakes2430 6 лет назад
Mind control
@paftaf
@paftaf 5 лет назад
Nope. It's a very stable system with many redundancy. Otherwise you'd fall from your bed on your head, and in the morning you'd be different person..
@kenconcepts
@kenconcepts 3 года назад
damnnn who ever created us is a fucking genius. this some posthuman futuristic shit that we'd create in the future but as megastructures and dyson spheres.
@BSin8413
@BSin8413 4 года назад
God is amazing
@blackbliz8246
@blackbliz8246 2 года назад
is not god
@pietajunior3437
@pietajunior3437 4 месяца назад
Which one?
@ahmedkhaled2641
@ahmedkhaled2641 2 года назад
that was better than breaking bad🥵
@froggo7215
@froggo7215 Год назад
This is sureal. Like a protein stick figure walking on some kind of molecular thread carrying a gooey information. how all of them know how to do all of this?
@JohnTepopo
@JohnTepopo Год назад
its like our brain is its own universe. and the universe we live in is someones synapses brain nerve and so on 😂
@dhavalpandav4440
@dhavalpandav4440 2 года назад
This theory 50% true but not expect protocol brain save in memory
@TARUN.2.2
@TARUN.2.2 3 года назад
Best
@adamogilvie6951
@adamogilvie6951 2 года назад
So based on the complexity and need I say design of systems like this, why do people still believe in Evelution? Something like this would simply not evolve. Glory to God!!!
@pietajunior3437
@pietajunior3437 4 месяца назад
Billions of years. Do you understand how much time that is?
@adamogilvie6951
@adamogilvie6951 4 месяца назад
​@pietajunior3437 To be honest, not enough time. Look, if you're an evolutionist, that's cool, but I just don't see all these complex processes coming into existence randomly.
@pietajunior3437
@pietajunior3437 4 месяца назад
@@adamogilvie6951 It has been conclusively proven that a plethora of organic compounds can be abiotically synthesised on meteors, comets etc. People have demonstrated how to synthesise such compounds from simple chemicals. Those processes potentially happen all the time in the universe. If the building blocks of life are so readily created, then I don't see what stops them from forming yet even more complex structures on planets, which give them the opportunity to do so, like Earth. Things on the nanoscale aren't organised. It's constant chaos, atoms flying in every direction, hitting each other and potentially creating bonds, only for that bond to break a moment later. Now think about trillions of atoms participating in this chaos, and then think about a trillion trillions. That still isn't even close to the actual amount. Billions of years is a ton of time for these organic compounds to merge and modify and form strange chemical systems. Then one of such "systems" could reach a, more or less, stable form; for example, a lipid membrane, which then might work as a storage for other strange chemical systems, etc.
@pietajunior3437
@pietajunior3437 4 месяца назад
@@adamogilvie6951 It has been conclusively proven that a plethora of organic compounds can be abiotically synthesised on meteors, comets etc. People have demonstrated how to synthesise such compounds from simple chemicals. Those processes potentially happen all the time in the universe. If the building blocks of life are so readily created, then I don't see what stops them from forming yet even more complex structures on planets, which give them the opportunity to do so, like Earth. Things on the nanoscale aren't organised. It's constant chaos, atoms flying in every direction, hitting each other and potentially creating bonds, only for that bond to break a moment later. Now think about trillions of atoms participating in this chaos, and then think about a trillion trillions. That still isn't even close to the actual amount. Billions of years is a ton of time for these organic compounds to merge and modify and form strange chemical systems. Then one of such "systems" could reach a, more or less, stable form; for example, a lipid membrane, which then might work as a storage for other strange chemical systems, etc.
@DJSHaKa
@DJSHaKa 4 года назад
Umm, what did i just watch, how did i get here - What has my life become? I did not search for this... HELP!
@mikekellerman4736
@mikekellerman4736 8 месяцев назад
God the Almighty doesn't get his title from man. He gives that title to hiself. All praise and glory go to him for he is our lord and redeemer the master of the universe!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
@DENTiins
@DENTiins Год назад
It seems like i am watching the trailer of Neurons…
@sportdutch
@sportdutch 4 года назад
Don't have too much water on the brain.
@SomaUlte
@SomaUlte 2 года назад
Jimmy Neutron Intro hahahahaha
@s.papadatos6711
@s.papadatos6711 3 года назад
Movie directed by Zack Snyder...
@alphagonist4748
@alphagonist4748 4 года назад
Damn
@fasterpastor1000
@fasterpastor1000 2 года назад
The human brain is the most complex thing science knows.
@silviaalexandrecordeiro8400
@silviaalexandrecordeiro8400 2 года назад
🌹🌎🌍🌏🌹
@muttleysmith726
@muttleysmith726 3 месяца назад
Phew, im tired of all this activity...😅
@davehibbs9111
@davehibbs9111 3 года назад
Thankless JOB 😂
@mraravindbaku6338
@mraravindbaku6338 3 года назад
*_stop procrastinating_*
@lacamendry1731
@lacamendry1731 4 года назад
Supercomputer That God Made Is Human Brain. Think about it. Human can make a Car. Making A Rocket to fly around the Galaxy, Not really. Can make a Artificial Intelligence.
@frankem4837
@frankem4837 5 лет назад
What did I just watch? 🤔😁
@khirywidener7874
@khirywidener7874 4 года назад
Allah Akbar
@akashbaiju6412
@akashbaiju6412 4 года назад
Whoa. That white thing is walking he has no eyes so how is he know that this is the way. 😂😂😂
@bookle5829
@bookle5829 2 года назад
goofy ahh walking cell
@DaddyBg69
@DaddyBg69 4 года назад
Wow damn animation as well as damn sound..
@seanotuleit
@seanotuleit 8 месяцев назад
What a masterpiece in animation of the synapse. It is outstanding. Thank you. I still foster a doubt about which structures help neurotransmitters travel along the axone. Could you please point if those are the microtubles or the microfilaments? Cheers!
@12centuries
@12centuries 4 года назад
This is so unbelievably, inconceivably complex. There's no way this wasn't designed.
@dhaneshtg8395
@dhaneshtg8395 3 года назад
Ya true .. we are come from a rock it seems ..my ass..
@huntercurts9998
@huntercurts9998 2 года назад
More like we have has literally billions of years to perfect this process
@12centuries
@12centuries 2 года назад
@@huntercurts9998 With all respect, I think you might not be realizing the full complexity of what's happening here.
@iamBlackGambit
@iamBlackGambit Год назад
@@huntercurts9998 hey this animation video of the brain had no designer, it took a while for this video to make and order itself..but it did, all on its own.............
@aykoc2001
@aykoc2001 Год назад
@@huntercurts9998 literally billions of years are not enough to perfect such a process. Today's computers are capable of doing trillions of calculations per second. But no company on earth uses random and natural selection mechanism to create software that delivers value. Please try to do a probabilistic calculation and you will see that it is impossible that the life is the result of a random process. There is one God. It is obvious by the witness of every tiny little cell's processes.
@smurProductionz
@smurProductionz 6 лет назад
My god these types of animations are amazing! What sort of software do they use?
@noahwilliams8996
@noahwilliams8996 6 лет назад
David Murphy IDK about this video but if you're interested in 3D animation you can check out programs like blender, Maya, or 3D Max.
@ClaraWang32356
@ClaraWang32356 5 лет назад
I believe they use ray tracing to make it seem 3d -- you should check it out!
@iamBlackGambit
@iamBlackGambit Год назад
"My God" your exactly right! He made the brain
@shadowsidesoamplified
@shadowsidesoamplified 4 года назад
holy shit the graphics are mindblowing
@Sushilajangid1989
@Sushilajangid1989 2 года назад
This much clearity before 7 yrs
@patatavoladora3006
@patatavoladora3006 2 года назад
bubu feo
@sitthuson
@sitthuson 3 года назад
wow feels like I'm watching a horror movie
@chizauz
@chizauz 2 года назад
how fast do the kinesin and dynein move? Do they move fast like the electrical light in the video moving fsat through the brain?
@flory6901
@flory6901 2 года назад
250 steps per second
@flory6901
@flory6901 2 года назад
Watch on utube A Day in the Life of a Motor Protein
@quillclock
@quillclock 2 года назад
this one is way better than the one you did back in 2013. this is way more why and how than the other one that just covered what
@mahmouddridi386
@mahmouddridi386 3 года назад
Quran "We will show them Our signs in the horizons and within themselves until it becomes clear to them that it is the truth. But is it not sufficient concerning your Lord that He is, over all things, a Witness?" Quran "Travel through the land and observe how He began creation. Then Allah will produce the final creation. Indeed Allah, over all things, is competent." Quran "Recite in the name of your Lord who created - Created man from a clinging substance. Recite, and your Lord is the most Generous - Who taught by the pen - Taught man that which he knew not.
@lostplanet1931
@lostplanet1931 3 года назад
Muhammad is a false prophet
@lostplanet1931
@lostplanet1931 3 года назад
He didn't get the Quran from God, he got it from the devil, he even choked him
@siddhikocharekar213
@siddhikocharekar213 4 месяца назад
Background music?
@aboutstudies123
@aboutstudies123 5 лет назад
Thank you Madam/Sir!
@RecoveryJimmy89
@RecoveryJimmy89 11 месяцев назад
This stuff is so cool
@jiahuiang1923
@jiahuiang1923 6 лет назад
I like your video
@isaiacaluza6712
@isaiacaluza6712 Год назад
yall really ate with this, the microtubules popped off so dramatically lmao
@chizauz
@chizauz 2 года назад
how many kinesin and dynein are moving through an axon?
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