🌿 Tryptophan vs 5-HTP: A Naturopathic Doctor’s Perspective
As a naturopathic doctor, I often get asked about tryptophan and 5-HTP. Which one is better and what are the differences? Here’s what you need to know:
👉 Tryptophan is an amino acid found in protein-rich foods like turkey, chicken, and eggs, and is converted into 5-HTP, which is then converted into serotonin. Serotonin is a neurotransmitter that helps regulate mood, sleep, and appetite. Tryptophan can also be converted down a different pathway called the kynurenin pathway, especially in those with higher levels of inflammation. Keep in mind that tryptophan also competes against other amino acids for transport across the blood brain barrier.
👉 5-HTP is a supplement that is a direct precursor to serotonin and can help with depression, anxiety, and insomnia. 5-HTP can readily cross the blood brain barrier without competition from other amino acids. 5-HTP turns into serotonin at a higher rate than tryptophan, so there is a risk of depleting dopamine. This is because the same enzyme is used to convert L-dopa into dopamine that is used to convert 5-HTP into serotonin.
Tryptophan and 5-HTP both have their place, but it depends on the unique needs of the individual and their medical history to determine which one, if any is best.
*It’s always important to consult with a healthcare provider before starting any new supplements.
*this is not medical advice
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30 май 2023
