TWiV 702: Year of the Pandemic

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For this first episode of 2021, the complete TWiV team reviews compelling virology stories of 2020, and thanks the multitude of guests who have helped us to navigate the pandemic, and our many listeners who turn to us for scientific facts.
Show notes at www.microbe.tv...
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- Who Am I? -
I’m Vincent Racaniello, Earth’s Virology Professor.
I’m also a professor of virology at Columbia University in New York. I’ve been doing research on viruses since 1976, and teaching virology in classrooms and online since 1999. On this RU-vid channel I share videos of my lectures, podcasts, and more.
New videos are uploaded every Thursday and Sunday mornings.
I don’t monetize my videos because it’s disruptive to learning. If you would like to support our work, go over to www.microbe.tv...
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#microbe #viruses #coronavirus #pandemic
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Опубликовано:

21 сен 2024

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Комментарии : 147

@briancase6180 3 года назад

TWiVers and Vincent in particular deserve the RU-vid equivalent of the Emmy award. And am additional award for public service, whatever that is called. Thank you TWiVers!

@Arun71150 3 года назад

TWIV has become my comfort blanket. Thank you Dr. Racaniello and company

@RayStraiter 3 года назад

Thank you all for being there for us who were desperate for the comfort your informative and honest conversations provided. Happy New Year!

@DavidL-ii7yn 3 года назад

Thank you TWIV team for your outstanding efforts.

@johnbouttell5827 3 года назад

24:54 You'll never be just a geeky podcast. You are one of the few reliable sources of information; better than the Guardian & the BBC.

@BM-ur4je 3 года назад

Thank you Dr. Racaniello and entire TWIV team for continuing these in-depth and frequent presentations. As a practicing ID-MBL Clinician experienced in SARS and now Covid-19 (former lab researcher in bacterial resistance) I have learned to enjoy virology as never previously during mandatory studies. The addition of Dr Daniel Griffin has been invaluable in merging lab-clinical application. from Toronto Canada - Barbara Mederski

@erik_carter_art 3 года назад

As I was watching this episode, I was just reflecting on how integral a part of my life TWiV has been over the years. It's incredible to think that TWiV has been a part of my life for literally one third of my entire lifespan! I remember back when you hit the 100th episode, and I even remember where I was sitting when I was listening to that episode with David Baltimore (in the lounge area of my Sophomore year dorm at UConn). TWiV also played a major part in my development as a scientist, and as a virologist specifically. I feel as though I've grown as a scientist in parallel with TWiV growing as a podcast over the past 11 years that I've been listening, and to think back on all that's happened over the years, I can't help but feel sentimental. Thanks for always keeping me company, and keeping me sane, when the world sometimes feel a bit crazy.

@carpediem5049 3 года назад

I also listen as I fall asleep then again when I wake up...to catch the portion I missed while I slept 🤗

@calvaryassemblyofgodsouthi8046 3 года назад

Me too. They are like watchmen on the wall.

@Amazing_missB 3 года назад

Same. There is something very comforting about the soft glow of my TV that houses gently bantering scientists. I have trouble sleeping but the TWiV team keeps me company and the science is calming.

@calvaryassemblyofgodsouthi8046 3 года назад

@@Amazing_missB Better than one of those white noise generators for putting babies to sleep!

@fedegufedegu 3 года назад

it happened to me too. several times. but i resume them all the times

@charlestongren2860 3 года назад

@@calvaryassemblyofgodsouthi8046 Well stated.

@janehale4402 3 года назад

We have a politician in Britain Michael Gove who said during the 2016 referendum "I think the people of this country have had enough of experts"it took covid-19 to prove him wrong ,we need experts such as yourselves to give us facts ,that enable us to behave appropriately., Thank you.

@rhuiden4086 3 года назад

Gove is an utter disgrace. It beggers belief that such people deem themselves worthy of governing our lives.

@janehale4402 3 года назад

What is even more unbelievable is that people continue to vote for him as their representative in parliament.

@shandard4861 3 года назад

There are a few of us that will continue to follow you when you are back to the geeky little podcast you use to be. 😁

@CricketsMa 3 года назад

Thank you, TWIV team, for an outstanding year!

@jmer9126 3 года назад

Thank you for caring about us ME/CFS people. Mine was definitely post viral according to Stanford ID dept, with super high antibodies to three different viruses. Twenty one years later, still struggling!

@mariannedonne7494 3 года назад

Watch Ivor cummins the fat emperor podcast. He is Irish. Brilliant researcher.

@kerrfamilylaw7487 3 года назад

I think you are all totally cool. I also fall asleep to twiv as I go through the 2020 shows (and then listen again in the morning because I fall asleep for faster than I think I will)

@quagapp 3 года назад

I meant the lectures on virology Vincent gives but also the seeing real scientists online and working together was interesting from a human point of view.

@Ulyssestnt 3 года назад

Its absolutely true that many depend on this podcast for accurate up to date information and to put all the research publications into context etc as well as an updated picture of the clinical situation and treatment protocols via Daniel ,its an oasis in a desert of misinformation and is so valuable as to be priceless. I was one of the geeky guys listening to the old iteration and didn't realize the contrast until you played part that older episode:) Happy new years everyone!

@cab5917 3 года назад

Happy New Year, hope this is a much better year by end of 2021. 12 months to go.

@solarwind907 3 года назад

Dr. R, all the co-hosts and guests provided a great public service to the US and the world in 2020. I learned a lot and I am not a scientist. I started telling people about what I was learning. They started thinking I was an expert. They asked me to speak at a zoom meeting and I was smart enough to direct them to the ASV site "chat with a virologist" and they got one on for about 1.5 hrs. About 25 average people got their questions answered by an expert for free. I'm not naive. I know there is a ton of mis-information out there and many outright lies. However you guys have been my resource for posting a lot of answers to comments on the Fox, Newsmax and other video sites where for whatever reason they got something way wrong. I know some of the people read my comments and thought about them because of the thoughtful replies I got. I had one reply from a tech in a lab that processed PCR tests and he filled in a lot of the blanks in my understanding. Anyway, as an old boss used to say to me once in a while, "ya dun good." Thank you all. Wish you the very best of New Years ahead!

@eastwestcoastkid 3 года назад

It’s sobering to listen to the first one on this-and listening to it now, knowing what we do now.

@lilylevental2808 3 года назад

Me too, crocheting my pandemic anxieties away while listening to reliable team of scientists. Thank you for all the podcasts

@Miata822 3 года назад

Good retrospective, but it ain't over yet.

@laniteshima9912 3 года назад

What a wonderful year-end wrap-up of 2020 to start off the new year with. Thank you TWiV team -- you're my favorite podcast to listen to on my long Sunday runs!

@dr.masoodkhanjogezai8492 3 года назад

Dear Vincent and others esteemed colleagues; Wishing all of you a happy new year 2021! Twiv discussions in 2020 have been remarkable on #Cor_Virus-2 pandemic, I have been watching since few months, which has been quite learning. Keep it up.

@quagapp 3 года назад

I think the team and others here have done a great job. People, ordinary people will keep interest as the subject is fascinating, even to people for whom it is not easy or not their main thing. Also it helps, indeed seeing this was kind of reassuring even here in NZ. And the lectures were interesting....

@Steve-Richter 3 года назад

But there has been no discussion of how to speed up vaccine testing and production. Nothing on where it is that people get infected, which is clearly in the home, from a family member recovering from an infection.

@charlestongren2860 3 года назад

@@Steve-Richter You've missed some episodes since January.

@quagapp 3 года назад

@@Steve-Richter People can be infected in hospitals, at home, in public places and events and so on. As to vaccines they have discussed those issues. The problem left hanging is the illusion that science is seperable from other things, such as politics, or business. Science is really applied common sense. It is a system of modelling things that is more or less accurate and more or less useful, and sometimes scientists work with "evil people" to make bombs and so on....But science never has been somehow objective and separate. I cant be, nothing can, we are social beings. These social factors and even certain philosophic factors etc (science is philosophy trying to do things): but from none of these things can it be separated. That is a vaguely Enlightenment idea which is dubious, although Rousseau was important I suppose and interesting to read. Obviously this year politics and human reactions (psychology) also became very important. Nor should we be surprised or even concerned too much about such as Trump. There are far worse things and have been far worse presidents in the US and around the world. Humans are fallible as science is. The idea of "Progress" is, like all abstractions, impossible to define. Even if parameters are taken as Johan Norberg does in his book "Progress" it is questionable. (Steven Pinker who he quotes has a similar optimistic book) But if his stats are reflective, then over time there has been "advances".

@js1mom 3 года назад

I'd never even heard of you all before covid...

@ImmunoMicro 3 года назад

Vincent Racaniello----Can you put all podcasts of Daniel Griffin (40+ for year 2020) as one series for us clinicians.

@charlestongren2860 3 года назад

Excellent idea. I went back & listened to them all again. It's like a fascinating thriller...or Stephen King story. But important to see how they discovered the different phases...

@deborahhebblethwaite1865 3 года назад

Yes than you for all that you do everyone. I listen to your program and Medcram to get proper scientific information for sars-cov2 and will stay on after this pandemic is over. The news drives me crazy, they often get the information wrong so it is calming for me to listen to your expertise..🙏🇨🇦

@briancase6180 3 года назад

It makes me sad that people forget that Fauchi has been through the hell that was the AIDS crisis in the 80s and 90s. He will be the first to tell you that he learned a lot from that experience. That has a lot to do with his level-headedness. That's not to diminish that aspect of his approach now: his dogged adherence to the science and nothing but the science should be admired the world over. He's a national hero, that's just the truth of it.

@rhuiden4086 3 года назад

Not really. Fauci flip flops all the time. He claimed on BBC in August that the PCR test was the "gold standard". Then in December his organisation the WHO released a clinical bulletin cautioning that PCR tests have been reporting a lot of false positives due to incorrect CT rates that pick up dead RNA. Yet governments are still wrongly using mass PCR testing to measure infectious virus in the populace. Professor Racianello has said pcr test does not tell you if the virus is live and infectious.

@MrMegaTubs 3 года назад

Really? Masks don't work. Masks do work. Lockdowns don't work, lockdowns do work. WHO advising not to lockdown, governments locking down. Mass economic devastation ensuing, lockdowns showing no change of infection rates. PCR-RT efficacy, false positive rates. Compared to 2018, deaths overall down. Pneumonia and flu symptom diagnosis compromised due to the covid-19 hysteria. Untested vaccines with regard to long term effects. Lack of advocacy for ivermectin, inefficient or lack of information on the effects of vitamin D deficiency. CEPI, agenda 201, Gates, WEF, all of this has been ignored or summed up as conspiracy. Mortality rates of 0.1 percent. PCR-RT forcing health workers to self isolate, possibly unnecessarily due to false positives causing unnecessary stain and under staffing. A pandemic that tou have to be tested to know you have. A pandemic that that caused care home related deaths in the region of 40% of the total. A pandemic where the push to avoid burden on healthcare institutions have caused more harm than good. A pandemic where pneumonia and flu deaths have disappeared. A pandemic where cancer diagnoses have been missed. A pandemic where the hysteria has and will continue to cause massive mental health issues. A pandemic where death statistics include anyone dying within 28 days of a positive test, no matter what the cause.

@ovrjoyd 3 года назад

So grateful I discovered this wonderful podcast. Thank you for all the work you do!

@astrohardy 3 года назад

you made my year. Thanks

@barbarahenninger6642 3 года назад

I do appreciate Fauci's level head. Recently I saw how he was surprised outside of his office building with a group of admirers singing him happy birthday. I bet when he first saw them he thought it was yet another group of people who wanted to verbally abuse him.

@philipperaimbault5895 3 года назад

Great 2020 year, thanks for your insights. Continue your work we need you still the way you are. Happy 2021!

@quagapp 3 года назад

Politics is always connected to Science and everything else. It is naive to think otherwise.

@KemptonLam 3 года назад

Thanks to the #TWiV team for great shows in 2020! Looking forward to new shows in 2021 and Wishing you all a Happy New Year! 27:13 Love Kathy's honesty here. This is what #ScienceInProgress feels like. We are (and must be) constantly learning and correcting ourselves as more data/evidences show up.

@joefrancis759 3 года назад

Happy New Year TWIV - discovering you was among the few highlights of my year!

@patriciahoke4722 3 года назад

New hospital slogan: Your choices for yourself today determine our choices for you tomorrow.

@ovrjoyd 3 года назад

COVID is front and center in everyone's mind. However, it reignited my interest in virology. Especially spillover and zoonosis. I learned most of what I know from my avian vets.

@Meeviche 3 года назад

Usually I just listen to the audio on my podcast app, but today I was in the mood to watch on RU-vid. Thanks for what you do.

@AJFish-rm6cv 3 года назад

Bravo brava bravo brava TWIV crew.

@kathleengallagher3473 3 года назад

"Do you love me?" got 21 million views in 4 days. This is 10x more than the number of vaccines we've been able to get into arms. Too bad we can't vaccinate through a viral RU-vid video.🤔

@pamelaruigh8185 3 года назад

Half the staff of our local hospital did not take the vaccine. Gives me so much confidence in attending their clinics. I want a vaccine and can't get one.

@quagapp 3 года назад

The weather is strange here in Auckland, I sometimes feel cold, although it is summer, and Auckland is running out of water. Has been a problem from 2020.

@jdr9419 3 года назад

So sorry about running out of water. I’m in Canada it’s winter but honestly it rains a little or a lot off and on since November 2020. We have lots of water.

@user-ou8pe9it8j 3 года назад

happy New Year everyone

@brigitteboulais5474 3 года назад

I agree with Brianne, you are very cool Vincent!!! Happy New Year Twiv Team!

@siemprelavictorie 3 года назад

You provide good information to the general public.

@zinnialady5153 3 года назад

I just found you guys. Really enjoyed this. Thank you.

@REALITYFACTSFIRST 3 года назад

3:21 Step in HERE for the Start of the Action - (introductions hellos climate reports are over - now the show kicks into gear) 3:21 - 13:40 Overview of the 2020 Year - 120 episodes in the year - a listing of the many guests that were on shows this year - a year of productivity (volume of show material production - far above any previous year - a year that saw TWiV move to Video Conference format - allowing audience to see who is speaking and give some more advanced communication options 13:40 A look at some of the top science piece of the past year 13:57 Vincent Leads out - with the "the compelling virology story pick" of - yes - of course COVID-19 a NOVEL to human beings Virus - he gives us a play through of 5 minutes of the first show of 2020 - were there is early talk on TWiV of this Novel Virus. 18:10 Wet Markets as the suspected source

@karl9460 3 года назад

I forget sometimes, how nice it used to be catching up on the news from around the world... what outbreak seems to be happening, what those outbreaks probably were, what the risks were and how outbreaks would come and go. I miss those days. My highlight of 2020 on TWiV was discovering how coronavirus antibodies do not always last for a long time, and how that information came about. I am amazed sometimes at how much the general public has got to know about viruses, I am just general public but with a fascination about viruses. I think we all knew one day we would see a pandemic, I am surprised at how much our governments can do but at the same time surprised at how ill prepared they were. I never would have imagined how much politics would play a part in an outbreak, I guess that was a happy ignorance. I hope, going forward, that they realise that if they can "try" to be better prepared it might mean they need to do less governmental stuff. I hope the population of the world realises how much we rely on each others health. Here is the 2021 and beyond. In many ways, we have been very lucky, it could have been a lot worse.

@fleetingdays 3 года назад

We have a four star US general in charge of vaccine distribution, no worries!

@davidhabart5323 3 года назад

Hi Vincent, thanks for your work. I have a question regarding the long term safety of mRNA vaccines. What can we learn from previous trials using mRNA vaccine against Flu, Zika or Rabies? They all a closed but keep recording delayed side effects. But I cannot find any reports published on that. Do you or our guests have some insight? Thanks!

@martinpollard8846 3 года назад

I listen to your audio at 2 X speed in bed at night, at normal speed i just fall asleep almost immediately

@deninetate 3 года назад

Nooooo. Don't leave out the video. I would miss seeing all of you.

@cheeheifoo9282 3 года назад

Yes, I will stick around when you go back to being a geeky broadcast.

@draconicfeline6177 3 года назад

Love the show, love the episode, but I gotta catch up so I'm moving on. Take care of yourselves!

@miguelgonzales8879 3 года назад

yeah, it is strange, but "thanks" to the coronavirus we are learning about our health, hope it helps to prevent something like it in the furute, this time we were not prepared enough.

@Sagacity61 3 года назад

Can we have a discussion (or can you refer me to previous TWIs) on any relationships of Coronaviruses to Yellow and Dengue fevers? The latter appear to have spikes like coronavirus. Could a spike-targeted vaccine (as used in Corona vaccines) be developed for these? Are they similar viruses, if not what makes them different? They are +single strand RNA viruses, no ?

@jdr9419 3 года назад

Happy New Year 🥳

@ovrjoyd 3 года назад

Vincent looks super cute in his T-shirt! ❤️

@Live.Vibe.Lasers 3 года назад

3yo son has 101.5 fever by my oral thermometer..100.x something by urgent cares IR thermometer. She couldnt get a pulse ox (he was screaming) but did get a good swab for PCR. Results in 3-6 days.

@AllenMorris3 3 года назад

In the Netherlands it seems that they originally planned to have the GPs give the vaccine shots (part of the healthcare system is that you have to have a GP). However they are switching to a model where very large groups of people will be vaccinated.

@debbietaylor4107 3 года назад

Is there a TWIV that includes discussion about Ivermectin? I’ve seen people promoting it lately on Facebook so I’m looking for info on it to help me be better informed to participate in discussions. I thought I remembered someone on this show saying they were going to talk about it on an upcoming episode but I can’t seem to find it. A doctor here in Oklahoma posted an article about it being bad for humans and there were passionate responses from proponents of the drug...

@joefrancis759 3 года назад

they had some discussion a few episodes back but the basic take up to now has continually been: the dose required for efficacy in vitro is lethal in mice and far above existing recommended dosing rates for other uses.

@dialessandro7260 3 года назад

Hi Vincent. A year later, China declares fewer than 100,000 cases of Covid, while growth does not stop globally. How do you think China is mitigating this pandemic?

@tamaryellin7043 3 года назад

"I want do to an hour-ish"..... = 1hr 37m in TWiV time LOL

@lampanish 3 года назад

Give the vaccines to Mr. Whippy for distribution.

@eastwestcoastkid 3 года назад

Guys- distance = velocity X time. Velocity is C ~ 186,000 miles/second-running the numbers one way 1.34 seconds approximately-so round time 2.68 seconds-not 30 seconds..

@jeffersonspace 3 года назад

Someone in medicine watching TWIV here will pick up some knowledge discussed. And it might be a fumbled muddy football - but, they will run with it. Crazy Parks Service Aide, Miami

@charlestongren2860 3 года назад

I wish someone could make a glossary of relevant terms to print out for reference. Online they're either way too small...or have thousands of terms.

@ajennerjahn 3 года назад

Yes, I’ve been thinking the same. A definition of the different types of vaccines. Infection vs disease. Pcr tests vs antigen vs antibody.

@fedegufedegu 3 года назад

Wonderful work. thank you. So Vincent was looking for wuhan on the map.... it will never happen again to look for it on the map. ps Kizzmekia the woman who saived the world, amazing maybe you write a book on it.

@toddthing 3 года назад

Vincent, if you read this, I wonder if you might opine on your recent(?) false positive and subsequent home "lateral assay" test you took which seemed to indicate that, yes, it was a false positive. Was your false positive from a PCR test? How common are false positives? I don't know if I even need to say it, but this test has been the center of much question and controversy. Do you find the PCR test to be useful? Is it accurate "enough"? Is it a legit application of that technology? (Is it true that this is the first time this test is being used in this way, that is, to diagnose a viral infection?) And, or course, I'd be happy to hear from any other experts in this field.

@nobodyknows3180 3 года назад

First!!!!

@coastwalker101 3 года назад

We will be more than happy to go back to random science. Though you could do episodes about emerging viral pathogens in pandemic frenzy style as necessary. We do have them all the time in animals and people.

@patriciahoke4722 3 года назад

There was a recent TWiV talking about the 219 (or so) new corona viruses found in China's caves in 2012. Scary stuff.

@coastwalker101 3 года назад

@@patriciahoke4722 I guess that science should be studying these viruses. I think that this is why it is really quite important to get round the political nonsense so that they can be studied for the benefit of the world.

@jameslawrence3666 3 года назад

Re London variant - although I'm totally with you in regards to caution being needed before jumping to conclusions and allowing political expediency to take over (Boris) I should report a sudden rise in London Covid deaths, after many months of near zero or very flat mortality. 10-14 days after the first significant rises in hospitalisations since April deaths started to climb and the 7 day average has jumped from 20-30 deaths /day to 75. The rate is similar with a tripling of deaths and a 4 fold increase in hospital admissions. This variant started making an impact in hospitalisations prior to the lifting of Lockdown 2.0.... not that much of the country enjoyed any relaxation restrictions to speak of. coronavirus.data.gov.uk/details/deaths?areaType=region&areaName=London

@quagapp 3 года назад

I liked a lot but I enjoyed the interview with Fred. His book looked fascinating....

@briancase6180 3 года назад

Maybe people don't know that RU-vid is the biggest music streaming service and by far if I'm not mistaken.

@valenciawatson2499 3 года назад

I'm an RN and I have been using your pod cast to educate myself, coworkers and family during this pandemic. I have 3 questions concerning the vaccines : 1) What cells in the body are being targeted to receive this mRNA? 2)Once the cells have begun producing the spike protein, what will stop this production since our bodies don't need this protein for anything other than producing an immune system response? Will the body destroy the cells that are making the spike protein? 3)If the production of this unwanted spike protein goes unchecked can it result in an autoimmune disease developing in the body? Maybe I'm over thinking but I don't trust this mRNA vaccine process. Please help! Thanks!

@Fahrenheit4051 3 года назад

Excellent podcast. Very informative as always, but I have one sticking point. If certain populations are having worse outcomes than others, why is race the first factor academics will look at? It just seems like focusing this much on race and using very broad terms like "person of color" ignores factors such as urban/rural, poor/wealthy, and other things that could paint a more complete picture, and leaves a lot of room for "missing the target". In cases where race is the _best_ predictor - It's one thing to use systemic racism as a null hypothesis (even that I'm not convinced is a good idea), but it's another to just leave it at that without considering alternatives. I'm not saying don't get political, and think it's good that we have these discussions - just that I disagree. I understand you guys are under a lot of pressure from your fellow academics, but if anyone has any second thoughts or disagreements on this topic it would be nice to hear them voiced honestly and respectfully.

@calvaryassemblyofgodsouthi8046 3 года назад

“After the Pandemic” After the Pandemic” After the Pandemic” After the Pandemic” After the Pandemic” After the Pandemic” After the Pandemic” After the Pandemic” After the Pandemic”

@charlestongren2860 3 года назад

I do the same thing.

@familiegeier4828 3 года назад

Hi! (30:00 ... ; chromosome 3 ... ) Yours Stefan Geier

@gordslater 3 года назад

un-presidented - pmsl

@Steve-Richter 3 года назад

Are there vaccine doses, in storage, which have not yet been used to inoculate? If true, why not sell those doses to free market distributors who will in turn setup for profit vaccination clinics and move quickly to administer every dose they can sell?

@clivekennedy6616 3 года назад

Yeah let's all avoid talking about lab manipulation.

@yangli8299 3 года назад

Being a scientit, speaking with evidence please. Of course, the first case was found in china, but there are many reports demonstrated that more earlier in other coutries and places. Please updata your knowledge, thanks. We have different culture, we also need to allowed different cultures existence in this world, just like different color people live in this world.

@charlestongren2860 3 года назад

Common occurrence that they always watch. Read The Coming Plague

@t.c.s.7724 3 года назад

Dr. Vincent, I am very happy for you and your TWIV podcast. I believe your years of working in virology have led to this moment. I don't believe your audience will abandon you post-covid. Caveat, please don't devolve into trivial political chit chat. Regarding Fauci, I still remember him telling everyone masks were unnecessary. I thought that advice was crazy at the time. I am perplexed by your panelists who insist on holding up Fauci as some kind of hero. Rather silly notion.

@eastwestcoastkid 3 года назад

Yes and as a good scientist, he adjusted his message when the data showed effectiveness-they mentioned that fact regarding what they knew, when.

@charlestongren2860 3 года назад

Was only re N95s as there was a shortage & needed to be saved for frontline HC workers. Later, he told everyone to wear non N95 masks.

@joefrancis759 3 года назад

@@eastwestcoastkid he admitted to deliberately misleading to avoid a rush on masks, it had nothing to do with data by his own statements