Dr. Leland Hu, clinical neuroradiologist and assistant professor of Radiology at Mayo Clinic in Arizona, talks about some of the common imaging techniques used in the diagnosis and treatment of Glioblastoma (GBM). Aside from the various strengths of brain tumor imaging, he will also discuss some of the persisting challenges, such as defining tumor extent and the differences that can exist within a single tumor. Learn about how overcoming these challenges could lead to advances in image-guided treatment (e.g., surgery, radiation) and personalized targeted drug therapy.
-Video Contents-
0:00 Introduction & Overview
3:11 Primary brain tumors
13:34 Diffusion Weighted Imaging (DWI)
16:01 Diffuse Tensor Imaging (DTI)
17:37 Diffusion Tensor (DTI) Tractography
18:16 Positron Emission Tomography (PET)
21:47 Glucose vs. Amino Acid (AA) PET
24:44 Extent of Resection
26:36 Function relates to neuroanatomy
28:57 Functional MRI (fMRI) brain mapping
33:11 Imaging non-enhancing tumor
44:08 Individualized patient models
51:28 Personalized Medicine
52:19 Targetable genetic aberrations
54:18 Intratumoral Heterogeneity
55:44 MRI models to bridge the gap
56:56 Dynamics of co-existing populations
58:26 Erlotinib: Regional response
5 сен 2024
