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What are mini brains? - Madeline Lancaster 

TED-Ed
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Shielded by our thick skulls and swaddled in layers of protective tissue, the human brain is extremely difficult to observe in action. Luckily, scientists can use brain organoids - pencil eraser-sized masses of cells that function like human brains but aren’t part of an organism - to look closer. How do they do it? And is it ethical? Madeline Lancaster shares how to make a brain in a lab.
Lesson by Madeline Lancaster, animation by Adam Wells.
Thank you so much to our patrons for your support! Without you this video would not be possible! Nik Maier, Robert Sukosd, Mark Morris, Tamás Drávai, Adi V, Peter Liu, Leora Allen, Hiroshi Uchiyama, Michal Salman, Julie Cummings-Debrot, Gilly , Ka-Hei Law, Maya Toll, Aleksandar Srbinovski, Jose Mamattah, Mauro Pellegrini, Ricardo Rendon Cepeda, Renhe Ji, Andrés Melo Gámez, Tim Leistikow, Moonlight , Shawar Khan, Chris, Alex Serbanescu, Megan Douglas, Barbara Smalley, Filip Dabrowski, Joe Giamartino, Clair Chen, Vik Nagjee, Karen Goepen-Wee, Della Palacios, Rui Rizzi, Bryan Blankenburg, Bah Becerra and Stephanie Perozo.

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6 сен 2024

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Комментарии : 633   
@TEDEd
@TEDEd 6 лет назад
Thank you so much to everyone who is supporting our nonprofit mission on patreon.com/teded! Check it out, if you want to know more about how you can get involved!
@MedatonOrtano
@MedatonOrtano 6 лет назад
I love the posthuman stuff like this. How about something cyborg-y in the future?
@thomasemil8909
@thomasemil8909 6 лет назад
TED-Ed can you return the super hero science series
@bongpich8620
@bongpich8620 6 лет назад
TED-Ed biko. Bnk
@corinagustiuc7360
@corinagustiuc7360 6 лет назад
Nu pagadi
@House24A
@House24A 6 лет назад
how do you made this video?
@abdullahmapari212
@abdullahmapari212 6 лет назад
*Excellent animation*
@Boufcon
@Boufcon 6 лет назад
This is incredible. Anyone has an idea how this animation was done ? With what kind of software ?
@pd1769
@pd1769 6 лет назад
Boufcon done by best animators with best softwares
@cleitonoliveira932
@cleitonoliveira932 6 лет назад
Its almost always made with Adobe After Effects.
@awwells1985
@awwells1985 6 лет назад
Thanks, man, I am the animator. Bit of After Effects, bit of 3D Software.
@eaSophia
@eaSophia 6 лет назад
Do you have any background in neuroscience? Man you sure are talented! I hope there are ways to can help you get recognized.
@AbstraktVisaj
@AbstraktVisaj 6 лет назад
Thank you TedEd for bringing us yet another informative video with amazing animation.
@RemingtonHillOfficial
@RemingtonHillOfficial 6 лет назад
I’m going to write a science fiction script for a movie about organoid rights
@veenamukesh
@veenamukesh 3 года назад
have you done it yet
@RemingtonHillOfficial
@RemingtonHillOfficial 3 года назад
@@veenamukesh in the finishing stages of pre-post-launch production, next we will be onto the reshoots of the contingency script for the fourth film, as long as we stay on track for the second prequel writing meetings during c*vid. But we do have a few thoughts on our first line of the movie! So close 💫
@rosiewu
@rosiewu 3 года назад
@@RemingtonHillOfficial Woah!!!!! Congratulations!
@stonerclone2616
@stonerclone2616 3 года назад
@@RemingtonHillOfficial damn thats awesome
@Silentgunner555
@Silentgunner555 3 года назад
Be careful, it may just become science fact
@minimalisticadvise6732
@minimalisticadvise6732 6 лет назад
Love the animation so simple yet captures each phenomenon beautifully especially the brains learning part. Also thank you for telling us about such research, I never knew this was already achieved 5 years ago and i am gonna be a doctor. In our country research are not given priority but learning by your videos is way to pass those walls.
@johndawson6057
@johndawson6057 Год назад
How's it going?
@parallel4
@parallel4 6 лет назад
What is a mini brain? It's what I have in my skull.
@swetasinha9542
@swetasinha9542 3 года назад
Lol 😂
@prakhar6334
@prakhar6334 3 года назад
oof that hits hard
@samueltheil4032
@samueltheil4032 3 года назад
Brain the size of a pencil eraser? So that scene in David Lynch's Eraserhead was legitimate head science, who knew.
@bookdream
@bookdream 6 лет назад
This is insanely fascinating, well explained, and beautifully animated
@siddhiraskar5464
@siddhiraskar5464 6 лет назад
Ahh...The animation is soo smooth My OCD brain is satisfied.
@fariesz6786
@fariesz6786 3 года назад
0:33 so you're saying there's a moat around my consciousness and it has duckies in it. accurate.
@jyotys9715
@jyotys9715 3 года назад
Haha yes, the cerebrospinal fluid inside the skull...Such a cute representation!
@pitodesign
@pitodesign 3 месяца назад
Mine has crocodiles
@TheRealEndead
@TheRealEndead 6 лет назад
The analogies used throughout the entire video is on point. Really makes the subject a lot easier to learn.
@canaryimpulse989
@canaryimpulse989 6 лет назад
TED-Ed >>> TEDTalks.
@mina_ashraf
@mina_ashraf 6 лет назад
they are all very informative and superb
@anime4life930
@anime4life930 4 года назад
Someone Else tik tok 😂😅
@HerMi.T
@HerMi.T 3 года назад
Ted talks analyse something in even more detail. That's why Ted talks is also great. Ted ed is great introduction.
@catfishofpl1707
@catfishofpl1707 6 лет назад
I KNOW WHAT THEY ARE! I have one!
@Strange_Man1911
@Strange_Man1911 6 лет назад
Ooo, how do dat feels? Me no has 1
@nirnayjain4989
@nirnayjain4989 4 года назад
Me too have 1 NVM i have nothing in my head just skull
@zuniga0331
@zuniga0331 2 года назад
🤣🤣🤣 I feel that one brah!
@pikerpoler
@pikerpoler 6 лет назад
it is just amazing how they utilize every bit of animation to deliver both the information and the message they want to deliver. when making this video, way more taught was put into it than it shows. that is part of why it is so good
@wingeddance
@wingeddance 6 лет назад
Please use this art style and genre of music from now on. It's so relaxing and helps me focus on the topic at hand.
@Saikool64
@Saikool64 6 лет назад
Sara Zeru the fun of TED-Ed is the varying styles. Maybe only when talking about brains, as they have used the same style for videos of the same topic.
@jenl732
@jenl732 6 лет назад
As a visual person I really love this animation at best. It keeps pace with the subtitles the most.
@YokubouTenshi
@YokubouTenshi 6 лет назад
0:54 Someone should tell the animator that schizophrenia isn't split personality.
@HerMi.T
@HerMi.T 3 года назад
True.
@Legitgaming838
@Legitgaming838 3 года назад
Maybe they put that because it was suppose to be shown as a hallucination.
@karengomez3143
@karengomez3143 3 года назад
I wouldn’t know how to draw it in a simple but actual representation
@indravargas1388
@indravargas1388 6 лет назад
I LOVED the animation of this video. Excellent as always, Ted-Ed.
@Rohitspc
@Rohitspc 6 лет назад
Ur voice should be universal
@Asterism_Desmos
@Asterism_Desmos 2 года назад
The animation was a different and familiar simultaneously and I loved every second.
@quantummight2972
@quantummight2972 6 лет назад
"What makes us human?" Didn't Aristotle kinda answered that by defining the different kinds of species in dependence with their capabilities?
@HerMi.T
@HerMi.T 3 года назад
Right, Aristotle theory really help us to understand why we are human beings. I think the better way to put this is that what makes us living organisms because other organisms also has brains but their dependence with situations and capabilities make them different from us.
@emilnavod67
@emilnavod67 3 года назад
You mean the featherless bipeds?
@laurynk4209
@laurynk4209 2 года назад
2:53 SQUID GAME?? phenomenal animation work btw
@jennyarguelles1045
@jennyarguelles1045 6 лет назад
I love the analogy - the way the brain organoid is likened to parts of the plane. Thank you, TED-Ed!
@curious2782
@curious2782 6 лет назад
The animating in this, like all Ted ed Vids, is fantastic.
@leonardosforzin6774
@leonardosforzin6774 6 лет назад
What about a video about consciousness and self-consciousness?
@salomonchambi
@salomonchambi 3 месяца назад
I was today years old when I first learned about this! amazing
@manavsingh7378
@manavsingh7378 6 лет назад
Which software you use for making these animations? I wanna learn too. It's amazing!
@islandfireballkill
@islandfireballkill 6 лет назад
Its probably made in adobe illustrator. You could find some online tutorials if you want to learn.
@manavsingh7378
@manavsingh7378 6 лет назад
Busted_Bullseye thank you
@carolynmmitchell2240
@carolynmmitchell2240 6 лет назад
go to skillshare.
@amandachen7770
@amandachen7770 6 лет назад
Ted ed hires animators for each video, which is why the art/illustrations vary for each one
@ErikSmuts
@ErikSmuts 4 месяца назад
It is interesting to note how many of the comments about what such a mini brain will be capable of doing have now been proven to be incorrect. Developments in the past couple of years enabled us to now allow such a mini brain to be connected to the outside world to give it inputs and collect outputs. Mini brains have been taught how to play Pong etc. The future potential is enormous…!
@robertgworek2497
@robertgworek2497 Месяц назад
Yep... I was watching this video and I was thinking that it aged so bad...
@realeyes8199
@realeyes8199 6 лет назад
Your amazing videos develop neuroplasticity in my brain.
@carolynmmitchell2240
@carolynmmitchell2240 6 лет назад
SACHIN SUNDARESAN I doubt that honestly.
@realeyes8199
@realeyes8199 6 лет назад
carolyn mmitchell Honesty is the best policy.😜😁
@akselspets3923
@akselspets3923 6 лет назад
Tha plane example was perfect, i love how you explain things, i wish u was my bilogi teatchers
@abdurraheem8033
@abdurraheem8033 6 лет назад
Thank you TED ED it's really helping me
@sairamved9614
@sairamved9614 6 лет назад
The animations in this are absolutely brilliant! I couldn't focus on the explanation the first time I watched this video (the explanation is amazing btw). I muted the video on one of my viewings just to observe the plethora of amazing graphic design and kinetic motion techniques used in this video... I love this channel because of the beautiful animations and amazing explanations! Keep up the good work.
@SuicideBunny6
@SuicideBunny6 6 лет назад
Makes me think how incredibly complex life is. A complete human/ animal/ ... just originates from 2 cells that came together.
@ahumanbeing
@ahumanbeing 3 года назад
Ted-Ed's animation is soooo good that I can't keep them in watch later. I can't even finish the video without pausing to comment how amazing the animation is!
@Questn
@Questn 6 лет назад
We will all grow a better one for ourselves. I definitely will.
@SotraEngine4
@SotraEngine4 6 лет назад
I like my brain
@Theo4871
@Theo4871 6 лет назад
But will it be you?
@nicosoftnt
@nicosoftnt 6 лет назад
Timerºº Very Nice question. I would say yes. Depends on how it's done. If its just an add-on that helps you think better. It would be okay. Now, if it disturbate the way you think, or some part of your brain is removed by "an improved one" Then... NO
@les_crow
@les_crow 6 лет назад
No it will not be you, same way your kids aren't you.
@Theo4871
@Theo4871 6 лет назад
NicosoftNT Indeed, "add-ons" may be a way to ensure it's still you. But well, our bodies are completely renewed as years pass, and we still feel like the same person, consciousness is still a big mystery.
@christienhernandez4794
@christienhernandez4794 3 года назад
I work in one of these labs! We use our spheroids as models for TBI, Ischemic stroke, neurotoxicology, and more!
@tasosalexiadis7748
@tasosalexiadis7748 3 года назад
Hi, researcher here from a different field. I was always wondering what software do you use?
@ProducerGio
@ProducerGio 6 лет назад
This animation are gonna make me cry
@bharatiyajokesparody
@bharatiyajokesparody 3 года назад
Very insightful! I really appreciate the hardwork y'all put in. Thank you!
@antonreshetnikov1671
@antonreshetnikov1671 6 лет назад
Really like the animation style! Not mentioning the way the topic explained. Thank you!
@samirpetrocelli6583
@samirpetrocelli6583 6 лет назад
For something to think in the way we know it, it has to have a body to know what is to see, touch, feel. It has to have a parents to know what is to be. The brain by it self is just and organ. Studying brain cells and studying thinking are two very differente things. You can know how a guitar produces sound, how a string vibrates, even how to tune it correctly, and still you will not know a bit about what music is.
@drsaifjr
@drsaifjr 6 лет назад
Very informative and easy to digest
@jowillll
@jowillll 3 года назад
the graphics and illustration in this vid >>
@yejinlee8920
@yejinlee8920 2 года назад
What a beautiful piece of art portraying a cutting-edge science!
@NabilaNazirkhan
@NabilaNazirkhan 6 лет назад
I can sense future bio-computers here. I recall to have read somewhere about possible future bio/organic storage which is thought to be more efficient, less energy consumption, durable as can with stand extreme measures and microscopic in size. This was non other than a certain bacteria’s DNA. Though it was still experimental it is very likely to be true in near future. Now imaging to how extent can this lab brain go? DNA as storage, then instead of busses to connect with processors within the computer, all of this is replaced with neurones and so on. Wow can’t imagine how many more break throughs will come out of this successful experiment. Probably the future might be less of a grey and more of green unlike as depicted in most sci-fic movies. ;)
@stonks7033
@stonks7033 3 года назад
Scientists make rally smart being then say we cant make them Get it
@PixelBytesPixelArtist
@PixelBytesPixelArtist 6 лет назад
For context: a bee has 100,000 neurons
@cortster12
@cortster12 6 лет назад
Considering human brains can be grown in a womb, a lab isn't that far fetched.
@jennyarguelles1045
@jennyarguelles1045 6 лет назад
I love the analogy. The way the brain organoid is compared to a plane. Thank you, TED-Ed!
@bluescreening
@bluescreening 6 лет назад
This animation style pleases me.
@anchaltrisal1345
@anchaltrisal1345 6 лет назад
Please please make a video on schizophrenia and how it affects the brain. Pleaseeeee
@carolynmmitchell2240
@carolynmmitchell2240 6 лет назад
Anchal Trisal tweaker.
@anchaltrisal1345
@anchaltrisal1345 6 лет назад
oh! my bad
@rayrocher6887
@rayrocher6887 18 дней назад
try to make , mini nerve cells , for spinal injured people. patients, could have interchangeable parts. The ability to fix cripple spines, is sooner than thought. keep up the great work. amen God bless you.
@tarekaljawi
@tarekaljawi 6 лет назад
man this is INSANE! never been so mind blown like this to scientific stuff before
@brianwyters2150
@brianwyters2150 6 лет назад
I thought this video would be about controllers for specific body parts. I recall watching a ted talk on how a crab chews using less than 100 cells(Somewhere around 100)to control the jaws.
@UjjwalRane
@UjjwalRane 6 лет назад
Great animation! Stands apart by its originality.
@reubenhayward6974
@reubenhayward6974 3 года назад
this animation is masterfully done... my god
@shyguy1845
@shyguy1845 6 лет назад
Kudos to Ted ed for very informative videos as always i just became one your patrons
@natarajboina7525
@natarajboina7525 6 лет назад
Thanks TED-Ed. This was amazing!
@kirbymarchbarcena
@kirbymarchbarcena 6 лет назад
The brain is really complex even this video shows it. We would take decades or even probably more than a century to completely know its secrets.
@utkarshgupta2943
@utkarshgupta2943 6 лет назад
Man how do you animate! Amazing!
@thecommonfool2110
@thecommonfool2110 6 лет назад
"He" doesnt animate, multiple people work together like a company Actually i think they *are* a company
@utkarshgupta2943
@utkarshgupta2943 6 лет назад
Can you tell me which software they use?
@DecemberGalaxy0
@DecemberGalaxy0 6 лет назад
Utkarsh Gupta must be adobe after effects and/or adobe premiere pro
@olive5671
@olive5671 6 лет назад
This is the BEST ANIMATIONS I've ever seen in a Ted-Ed video!
@blastoff2moon429
@blastoff2moon429 6 лет назад
Classic animation , I love soooo much . Love form India !!!!
@eunhyoukshin7777
@eunhyoukshin7777 6 лет назад
The animation is so strikingly good
@MusiCaninesTheMusicalDogs
@MusiCaninesTheMusicalDogs 6 лет назад
Beautiful animation! Great content!
@alimreyes2524
@alimreyes2524 6 лет назад
I thin this is one of my favorite looking videos so far from this channel
@rvxn
@rvxn 3 года назад
Send your Animator to our schools.
@ayaanqureshi9926
@ayaanqureshi9926 6 лет назад
Literally amazing animation!! Can you explain the dynamo effect which cause the earths magnetic field to work! Because if we are saying that earth has its magnetic field due to its molten iron core, than the core shouldn't be a magnetic thing as magnet looses its magnetism on heating! Plzz answer if you can!
@Agropotato75
@Agropotato75 6 лет назад
This video is a work of art
@nadi106100
@nadi106100 6 лет назад
loved the animation on that video!
@xxss4everxx
@xxss4everxx 6 лет назад
To know the answer of the age-old question , scientists must study both brain and heart. Also the brain cells in the heart.
@Epicvampire800
@Epicvampire800 6 лет назад
Just because the mini-brain isnt set up like our brains doesnt necessarily mean it can't think. I dont think it could develop consciousness the way we think of it, but it probably does perceive even if it doesnt attribute any meaning to those perceptions. Also 1 cm is not small for a brain, ants are fully functional organisms with complex behaviors and their brains are way smaller.
@jacops419
@jacops419 6 лет назад
Those animations are amazing
@GREY666KILLER
@GREY666KILLER 6 лет назад
Mini brain blown!
@michaellukiman3483
@michaellukiman3483 6 лет назад
Best animation yet, subjective of course. The symbolism and somehow perfect representations better than most. Bar none.
@demondwilson706
@demondwilson706 6 лет назад
That graphic for schizophrenia was pretty cool
@sionmarak1916
@sionmarak1916 6 лет назад
Best channel for education.
@shinjitobe8297
@shinjitobe8297 6 лет назад
Nope it is THE best channel for education
@ryanmohan3041
@ryanmohan3041 6 лет назад
Thank you TED for all of these amazing videos - everyone
@jvb5590
@jvb5590 6 лет назад
Better graphics this time. Thank you.
@anudeepandy989
@anudeepandy989 6 лет назад
The animation is Nooice! 👌👏
@user-dc4ok8im3u
@user-dc4ok8im3u 6 лет назад
It is still possible that there is a conciousness
@oldcowbb
@oldcowbb 6 лет назад
don't let the christians know we are growing little brains in the lab
@LughSummerson
@LughSummerson 6 лет назад
They're full-size brains to them.
@pelecranileboi9011
@pelecranileboi9011 4 года назад
@@LughSummerson lmæœ
@HerMi.T
@HerMi.T 3 года назад
But why? Can you explain it?
@ContinualImprovement
@ContinualImprovement 6 лет назад
Yes as I make a living selling human brains. The only problem is that I can’t figure out how to sell consciousness. If I could do that I’d be rich.
@Scatrex
@Scatrex 6 лет назад
You'd be rich, because it is in short supply.
@asadullahkhan3825
@asadullahkhan3825 6 лет назад
Continual Improvement You said you make a living selling mini brains. I am interested in buying your organoids for medical research. Please whatsapp me +923009445355
@andrewpereira888
@andrewpereira888 6 лет назад
I wish I could donate to you guys because you haven’t only entertained me but also informed me about the wonders of this world. But im only a kid who doesn’t have a patreon account :(
@user-it2kq4ty9q
@user-it2kq4ty9q 5 лет назад
Minibrains have grown in 2019 now they reached 1million neurons and twitched a muscle
@dheerajlakkaraju8168
@dheerajlakkaraju8168 6 лет назад
Wow! I did not know that. This is why I like Ted-ed.
@perrysanders2899
@perrysanders2899 6 лет назад
Love these videos. Keep it up
@davidgranity7679
@davidgranity7679 6 лет назад
That is great animation concept. Thank you for that animators
@ifurkend
@ifurkend 6 лет назад
I can already see some writers begin writing horror/dystopian story about an apocalyptic world ruled by an overlord grown from a mini brain.
@tesconstamylo
@tesconstamylo 6 лет назад
Great work and very easy to understand! Yet we are still missing the big picture including the effects of diet, sleep on our cortex and the effects of diseases on the construction and deconstruction of synapses basically our memories and learning!
@stayinawesum
@stayinawesum 6 лет назад
what is the differences between learning in ur puberty/childhood vs at 20, in terms of art/creativity, philosophy, science, physical skills like sports/martial arts, is it too late and whats the differences
@chrismason6857
@chrismason6857 6 лет назад
How can I donate skin cells to study the effects of chronic pain on the brain?
@kadarjeerman3953
@kadarjeerman3953 6 лет назад
+Chris Mason: You could rub your finger over your skin. Then you'd have *_THOUSANDS_* of skin cells to work with. Or if you want *_alive_* skin, you could get a doctor, and have some sort of biopsy!
@blurabbit2171
@blurabbit2171 6 лет назад
And this is how humanity gains immortality....I'm never going to get to retire
@diemer2433
@diemer2433 6 лет назад
We can mimic Logan's brain though, I show you nothing
@maddio3
@maddio3 6 лет назад
i can't get over the animation
@apen3493
@apen3493 6 лет назад
I love this channel
@sidd450
@sidd450 6 лет назад
Awesome efforts!!!! I appreciate it I'm 16 but I'll luv to appreciate it!!!!
@TheNavieus
@TheNavieus 6 лет назад
Amazing Video.Great concept and supported by a brilliant animation.
@bexiah
@bexiah 6 лет назад
The animation is really cute. I feel like watching Monument Valley if it's used to explain science. Definitely love it!
@mythi7059
@mythi7059 6 лет назад
*I love the new animation style!!!*
@hektur6770
@hektur6770 6 лет назад
If this advances further, then we could technically grow our own robo-humans, and then maybe an actual human. Yes, the narrator said these brains don't have consciousness, but if I understood correctly, that's because we can't really make them any bigger or wire them correctly. If we made a suit capable of supplying everything a normal brain would need, then we could theoretically grow a mini brain into a normal size, although it still wouldn't be wired correctly. However, if we managed to link up sensors that feed the brain info like our own (sight, touch, etc.), and hooked them up to the correct parts, the brain may be able to learn and realize what's around it. If we found a way to make the brains learn enough to be able to discern different objects and other such things, we could give it a robotic body and see if it begins to learn how to move around. Even further in the future, if this succeeds, we could try to put the brain in organic body of artificially grown limbs (Which are already a science, although it's still evolving). If we manage to do this, even if it isn't that well done, it will spell out a future of artificially grown humans, and give us the possibility to make humans with bodies that excel in certain areas; for example, we could grow limbs that are stronger and more durable than your typical human's. Basically, we could soon begin to grow super humans and make them fight robots for us
@SoumOrg
@SoumOrg 6 лет назад
sitting on our shoulders is the *most complex* thing in our universe
@chijunky6145
@chijunky6145 6 лет назад
by what definition? i mean if it's the number of neurons and neural connections, elephants have more.
@SoumOrg
@SoumOrg 6 лет назад
Rena Cava elephants watch RU-vid for sure, so intelligent they are!
@chijunky6145
@chijunky6145 6 лет назад
you said complex, not intelligent .-.
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What happens if an engineered virus escapes the lab?
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