All 19 references are linked in the video's description 💊MicroVitamin (multivitamin & mineral that I take): drstanfield.com/products/microvitamin 📜Roadmap - how to look young & feel strong: drstanfield.com/pages/roadmap
Ancel Benjamin Keys was a scientific fraud, and you, Brad Stanfield, still haven't realized it. His Seven Countries Study was a scientific scam, as it actually had data from 20 countries, but he removed the thirteen countries that went against his theory.
Bu the way, olive oil and avocado are rich in monounsaturated fats, no in polyunsaturated fats. Avocado, in fact, has more saturated fat than polyunsaturated fat (15% vs 10%). Your advice in favor of 'unsaturated' fats is misleading.
The DASH diet is falling apart. Research has shown that both the low sodium and low fat components are counterproductive. All of the benefit seems to be coming from the low carb component, and perhaps the resulting low calories that come from such a restrictive diet.
Dr Brad- Ansel Keyes "7 countries" study was actually a study of 22 countries. Ansel selected the 7 countries that would most agree with his saturated fat hypothesis. He purposely discarded countries like France and Denmark from his study that have huge intakes of saturated fat yet some of the lowest heart disease rates and highest longevity in Europe. It's important to note Ansel was a 7th day Adventist and part of the temperance movement- he believed for religious reasons that a vegetarian diet was superior and that ended up clearly reflected as bias in the data he discarded to pare his 22 country study down to a "7 country study".
@@stancartmankennythat's cherry-picking, what about pizza hut and other fast food chains selling cheesy bread? Remove your bias and consume pizza with cauliflower on it 😂
I would recommend people to read the Cochrane Review of saturated fat cited at 7:28. It is remarkably underwhelming in its conclusions. “We found little or no effect of reducing saturated fat on all‐cause mortality or cardiovascular mortality.”
Most diet randomized controlled trials do not run long enough to detect a mortality difference. Instead, they are powered for cardiovascular events such as heart attacks. Here, the data shows a 17% reduction in the risk of cardiovascular disease
@@DrBradStanfield The review goes on to state that, “56 people need to reduce their saturated fat intake for ~four years for one person to avoid experiencing a CVD event.” This high number to treat doesn’t match my expectation of a 17% reduction. I suppose it must be relative to a small number.
Lower saturated fat applies if you are eating carbs. Because if you eat carbs and fat together, carbs get used, saturated fat queues up in the blood and gets taken to storage. If you go low carb there is no queue, all the fat will get used because it is difficult to eat too much fat without getting full unless you are eating nuts or cream etc.
@@briandriscoll1480 conventional widsom would suggest satiety is more closesly linked to stomach fullness than it is fat consumption; fat has to be twice as satiating as carbs I don't think a 50% full stomach of fat satiates the average person more than a 70%-90% full stomach of fat and carbs
@@zentzu4003 And for that reason you can eat less and get full quicker without spiking insulin. You can count the calories or learn about calories in different things for example it is easy to overeat walnuts or cream which are very high calorie vs their size. But try overeating chicken thighs with fat on I am full after two (400cal), but if I had two slices of pizza also 400cal I would not be full.
At one point the video says that the minimum recommended protein is 0.8 grams/kg. It then says 3.6 grams/lb. Assuming that the first metric number was correct, then the Imperial unit number should be 0.36 grams/ lb. Not 3.6 grams/ lb.
At 0:36 You're correct he did misspeak there. But it does actually show what you're saying, it literally shows .36. apparently he just accidentally said 3.6 even though it shows .36. he could probably remove that little clip using RU-vid Studio and it wouldn't affect the video at all. Funny I just realized the time stamp is also 36 seconds in... Something with these two numbers is creepy!
I put Pizza in the worst foods you can eat, bread, seed oil, highly addictive, super high calorie density. It is part or the reason of the obesity pandemic.
@@ahallock Of course I'm talking about your standard pizza which 95% of people eat, bread, oil, and cheese. Or more like 800 calories a slice, like the Costco slices. I see people eating a half pie of that or like 6 slices in one sitting, or close to 5000 calories. This stuff is deadly.
I'll stick to my keto diet which includes animal fats and red meat thanks. I've become insulin sensitive, lost lots of weight, feel fuller for longer and normalised my blood sugar levels. In fact, I feel healthier than ever before.
I wouldve prefered to lose weight using a healtht diet that reduces my risk of cardiovascular events in the future but you do you boo. Tell me how the angina feels in 20-40 years.
@@proper2979 ok I'll do boo whatever that's supposed to mean. I've been on a keto diet now for 2 years and not sure where your angina scare comes from but if you think I have high cholesterol, think again. That is also well within normal limits and I'm 56. Have a nice day.
@@gordonalexander4843 Similar here, but for 3 years of ketogenic carnivore, and only 36 years old. Though my grandfather who served in ww2, and was a butcher amongst other jobs, and ate mostly meat most of his life recently turned 98 this year and can still walk and chat. Even 5 years ago he was still driving and doing bike marathons, so maybe it's genetics? Then again 3 years ago I weighed twice as much as I do now. Also "risk" is a casual statement of fact, inferring proper2979 say that he has been misinformed that such a diet, which is based on nutritional science showing correlations and statistical data can establish "cause and effect", I'm sorry to say this to him, but such nutritional studies don't exist, if he thinks they do, that would mean he believes that nutritional science performs illegal "human" experimentation.
Been following your channel for a few years now, Dr. Brad. While most of your videos are of great informational value already, I found this one in particular extraordinary. So much valuable information, presented in a super clear way, directly to the point while being fully up-to-date. Very much appreciated.
@DrBradStanfield can you give us a 'day in the life' of your diet and what meals you eat for breakfast, lunch, dinner (and snacks) to comply with these guidelines? I think some examples in context would be super helpful!
70 year old weight lifter here. I eat healthy and have reasonably increased my protein intake to about .8 gm per lb of body weight.. i have noticed an increase of muscle mass..i suspect additional protein is needed for older individuals as our bodies are not as efficient..
Our bodies are efficient with protein at any age. The issue is leucine. Leucine activates mtor which stimulate muscle protein synthesis. As we age leucine becomes less effective at activating mtor. This is where weight training comes in, which is a much better activator of mtor. Adding more protein as we age is not the answer. What makes our body efficient with protein is to eat less protein (although that's not what I'm recommending). See the research of Nicholas Burd using isotope tracers. The more protein we eat, it just gets turned into glucose. Efficiency would simply mean less amino acids turning into glucose and being used to create protein for enzymes, hemoglobin, muscle, etc. Weight training is needed, not 0.8 g/lb of protein. 0.6 g/lb should be fine if you lift weights. If you eat a well-balanced diet, protein will take care of itself even for vegans. When you exercise, you require more calories, with more calories come more protein. There's zero evidence that high protein is good for healthy and longevity. Strength is important which requires weight training, especially as we age. I'm 60, and can deadlift over twice my weight. I weigh 185 lbs at 6'2" and deadlift 360 lbs. I plan to be lifting over 400 lbs in six months. High protein is not a factor. I've gained over 20 lbs of muscle in the last two years and protein had nothing to do with it.
It seems to me whether you follow a dash, mediterranean, high protein, low carb, high fibre or keto diet one of the important factors is it forces you to look at food nutrition labels and away from highly processed food towards cooking and creating your own meals. Which I think is an important factor beyond macros.
Just got to find the people who make them good then there is no catch. I would happily eat a healthier pizza. I have eaten the greatest tasting vegan fish, ice-cream cheesecake etc but when I try to make it, nope, rubbish lol
TIL my diet is nearly perfect after optimizing it for nearly a year 😊 I'm getting around 1.7g/kg protein per day, from nonfat greek yogurt, white meat chicken, beans/lentils, and fish (salmon or tuna eaten 3-4 times a week). I target 55g of fiber per day, usually getting around 60g. This is as high as I can reliably go before I get digestive issues. I went from struggling to even find foods that contained fiber to having the opposite problem: if I don't monitor my intake I am likely to get too much! I eat a lot of whole grains, seeds, nuts, fruit, and veggies. I want to dial up the veggies a bit in relation to the others which is my next goal. I have been relentlessly driving my added sugar, saturated fat, and sodium levels down. Most days I'm at 0g refined sugars, and my saturated fat is usually below 5% of my daily calories. I feel better than I ever have in my life. Lots of the information I used to arrive here was from this and other similar health channels, so please keep up the good work and keep giving us these evidence based takes. 💪
That's a really odd conclusion you've come to there. Fortunately we don't depend on mice and human outcome data, like the doctor shared, evidences that humans do excellent on carbohydrates as well, complete, complex carbohydrates from whole vegan foods not bastardized carbs that people over generalize from in an attempt to provide good news for their bad habits.
Some guy weighing 600lbs fasted for a whole year and ended up with normal bodyweight afterwards. Normal body weight humans can only go about 30 days without food.
What I'm implying is that humans have adapted over their evolutionary course to take advantage of the processes of bot feasting and fasting, so much so, that evolution has provided man with the ability to continue extended periods of fasting. That isn't the case with mice, who have an extremely fast metabolism and limited bodyfat.
I replace my added sodium with potassium chloride. There continues to be some sodium in my diet from a smattering of condiments. I have been doing this for about 6 years. My BP is dramtically lower than it was the previous decade. And from my perspective the taste is an acceptable version of salty. So I can still have my salty food, which is somewhat nice as I find my dietary choices become more and more restricted as I age. There's pretty good interventional trial support for this. I also add some magnesium, which also has some pretty good evidence. Which has totally eliminated age related muscle cramping. I decided to start doing this when I noted in my medical practice that the vast majority of patients coming through my office, ER and OR were magnesium deficient. In some of those they presented with dramatic cardiac rhythm disturbance. Pretty good summary, thanks. I think most of the "low carb" studies use an extremely lax definition of low carb,
@@reason3581 but we don’t really know that it’s the amino acid ratio, right? That’s just the proposed mechanism? We don’t know if this is independent of the fats contained, cooking methods, fiber?
Thank you for reporting clearly the facts, Dr. Brad. I appreciate how clearly you communicate through the clutter. You are a RU-vid treasure. Please keep it up. People need to hear what you have to say.
You didn't talk much about those who have diabetes or early stage diabetes. I have diabetes and the only way I can control it is to keep my carbs as close to zero as possible.
Losing 10% of my weight even though not over weight to start with, reversed my diabetes for me. And you don't need low carb for that. You do need caloric deficit
@@charlesfuchspeople get diabetes mainly from eating too many carbohydrates for so many years that their insulin can’t keep up with blood sugar and the pancreas becomes overburdened.
The reason why low protein diet works is that the body makes autophagy of the cancerous and old cells to suplement the low protein diet. Also the capacity of the body to create new cells is lower ( less protein to go around and grow but just to maintain ) - lower metabolism - that prologs the life of organism. The autophagy is beneficial as only the most healthy and less defect cells remain to duplicate to the next generation. There is around 20% increase in life span just by low-protein and medium-to low calorie diet. That could mean 15-20 years.
Longo has probably got the best cv I’ve seen on longevity research spanning since the 90s under Roy Walford studying calorie-restriction and aging, I know it’s tempting to do a sweep of research papers and come to conclusions like this but I think maybe an interview with Longo would help clarify matters. Keep in mind, Diet recommendations from someone’s lab who did centenarian studies on blue zones, ppl living to 100-120 years of lifestyle and diet. Trumps anything ppl are guessing might achieve the same results, it’s like ignoring what’s immediately infront of us. Sarcopenia is minimised in these ppl because they are lifetime active
Yet Peter Attia, Rhonda Patrick and Layne Norton all have diverged from Longo's diet recommendations. Dr Patrick even hosted him on one of her podcasts awhile ago. Also don't forget that Longo has a commercial interest in his fasting mimicking diet.
@@Greg_ChockNone of them are longevity scientist, and at least Layne have being shown to be biased too, especially since he is very into fitness (all of them are to an extent). I personally am compelled by arguments from both sides and think that maybe they are addressing somewhat different things.
@@elhant4994 Peter Attia is a medical doctor and runs a longevity service for the rich. Layne has a PhD in nutrition. Rhonda Patrick does research on aging in people. Does being into fitness disqualify their guidance?
@@Greg_Chockcommercial interest?? You mean the money that goes straight back into helping cancer patients get better outcomes from chemotherapy and fasting diets.. that commercial interest. I think you are confusing Attia and Rhonda as the ppl to follow in this area, when it’s entirely backwards. Being on RU-vid doesn’t make their cv any bigger, and doesn’t get them a Nobel prize nomination… Diet recommendations from someone’s lab who did centenarian studies on blue zones, ppl living to 100-120 years of lifestyle and diet. Trumps anything ppl are guessing might achieve the same results, it’s like ignoring what’s immediately infront of us
The problem of translating those mice studies (low protein, in that context) to humans is that they grossly underestimate the negative impact that frailty has in human health in older people. Given that lab mice die almost only from cancer, any small effect a low protein diet might have on cancer (such as modestly lower IGF-1 levels) will have a higher contribution to overall lifespan.
centenarians in the blue zones have been accounted for in longevity research, frailty doesn’t appear to be an issue for them even with their modest protein consumption. We shouldn’t be guessing that high protein is better as that’s what is being done, we actually have the centenarians to study who are active and mobile today
@@Fab666. Sure, protein consumption is not the end all be all of maintaining a good body composition, you're not gonna get fit by being a couch potato that eats 10g of protein/kg. The question is wether the net effect of consuming higher protein is positive, negative or neutral, not if the effect is so big that it is impossible to be healthy without it. I agree with Brad that the data seems to suggest that the overall effect is positive, but that is not to say that it is so big as to be impossible to be healthy without eating high protein or that future data couldn't prove that conclusion wrong.
@@Fab666. Also, legume consumption is highly associated with increased lifespan and overall health, and they're a great source of protein, people also eat a lot of fish in many blue zones, so I wouldn't be surprised if their daily protein consumption was above the 0.8 g/pound recomendation to begin with due to legume and fish consumption.
@@PaulHumphreys-q3eand you mean if we stop listening to science, and significant long time anecdotes corroborated by science, and our own experience? Meanwhile if you look at what people are actually doing in the grocery store, like 98 plus percent aren't eating plants. And they are all sick. For some reason your story doesn't add up.
Great video. You somehow managed to tie all the conflicting and important studies over the last 50 years together into a short video that makes so much sense. Essentially, eat relatively high protein, healthy fats, complex carbs with lots of fiber, avoid sugar and simple carbs, and limit salt. Plant protein is great because it limits saturated fat and adds fiber.
Cottage cheese has a bit to many carbs for me personally. I make mine with ground pork, egg yolks, and parmesan cheese for crust. Then I use whole mozzarella with bacon to top it.
After bringing up Rapamycin and the counter effect of meat/protein you just jumped topic. Rapamycin is active at inhibiting mTor for about 48 hrs. To aid in the autophagy, I hold off of high protein meals and intense exercise for those 48 hrs. Game on the rest of the week. Two years so far and feeling great at 63. Cheers!
I am starting to take rapamycin next week too. Can you tell me when is the best time of a day to take and what is your dosage? I think to take every Saturday evening with 6mg. Rest on Sunday and do minor exercises on Monday. Resume gym workout from Tuesday to Saturday. Thanks
@@joeextraknow2854 That is a complex and individualized question. If you plan on doing so without at least the awareness of your doctor, there are online groups that share their anecdotal experiences that may align with your reasons and goals. Being that you are starting out with 6 mg off the bat, tells me you should do a bit more research so you know what response to look for. I haven't known anyone to start with six unless you're a 40 year old body builder. Not trying to come off flip here, I am a huge proponent of it. I can't make it a conversation here. Best wishes though.
@@dylan.-6527 Sounds possible. MTor toggling is a natural process that diminishes as we age. As we age, there are more and more external factors that keep the autophagy cycle from occurring. Lifestyle choices that contribute to inflammation certainly push up mTor, conversely anti-inflammatory foods and activities suppress it. It's not a magic pill by itself. I really like how the good doctor here views supplementing our lives in moderation to maximize health results.
To be clear, there's a massive difference in using a drug to block mTOR, versus trying to influence mTOR via diet. I'm very excited about the potential of Rapamycin (hence my study). That's separate to diet
A whole foods plant-based diet seems to be the best for reducing heart disease, diabetes and cancer risk, also longevity. It is also better for the planet and animals.
Wrong on all counts. None of us carnivores are dropping dead from heart attacks or cancer. In fact a keto/carnivore diet is part of the metabolic cure for cancer. Nothing is better for the environment and regenerative agriculture.
@@sahahaah427 What do you think the corn that cows are fed on is watered with? A cow eats vastly more than a human in order to produce much less meat. Very few people eat honey. It’s too expensive.
@@sahahaah427The animals you eat consume plants. So yes plant based is best because by removing animals younwill have less plant agriculture not more.
There is no nutritional study that can prove cause and effect relation to determine risk with any human diet. It doesn't exist. We have opinions based upon correlation studies based around self reporting, or uncontrollable or biased data collection that cannot control for all variables without committing to illegal human experimentation. So to say that something is best to reduce risk, is to say a lie, as it's an opinion not rooted in hard science, of cause and effect. Also it is your opinion that it is better for the planet an animals. Better in what way? For the water ways filled with pesticides and the destroyed soil from mono cropping to support an all plant based diet? Is it better because the cows don't even get a chance to live and exist as they are replaced by fields full of dead insects? Perhaps it is better as the planet just likes plants more and all animals should just not be around anymore?
Wow! This is the best 15 minutes I spent on RU-vid. Really covered all the key things regarding diet, health, and longevity from evidence-based information. Thank you so much!!! 👍👍👍🙏🧡
Thanks for this overview, I find your videos among the very most informative and trustworthy. Is there a short answer to this question - did those who replaced animal protein with plant protein and got better results, were all other factors accounted for? Ie, did those people just happen to be healthier eaters as one would suspect, or were they similar profile people who made the switch?
"People are concerned that the researchers had conflicts of interest, but here in the report they have said that they don't have conflicts of interests". OK, that's alright then. Everyone in every walk of life is completely upfront and doesn't try to pull the wool over your eyes. I'm not saying that they do have conflicts, but I think really believing it should involve more than looking at that line of the report.
If a research team is deceptive enough to shape your opinions with misleading statistics, poor methods, and false presuppositions, solely to support their preconceived conclusions, then why on Earth would anybody trust their conflict-of-interest disclosure statements?
For about a year now I've noticed my heart struggling. I told the doctors but they didn't find anything wrong with it. But when I sit, I feel it beating irregularly. I'm trying to exercise more and feel OK but I'm worried. I turned 40 recently and had an unhealthy life but also tried to exercise.
According to a nutritionist I was following beans which is a good source of fiber are beneficial because the fiber she says gobles up triglycerides which then go to the liver and is excreted through number two
I'd be interested to know your thoughts on oil. Olive oil seems great, but I gather it denatures into something not so great when used for frying. Coconut oil has been getting some excellent reviews from some doctors, and a lot of RU-vid sources - as well as anecdotally in comments.
It's all smoke with coconut oil, to get the benefits of it you would have to ingest crazy amounts of it. Not to mention it has a lower burning point which makes it worse for cooking. Also it seems to change the gut biome more than even canola oil does. which doesnt seem to be a good thing.
@@newguy1122 The burning point seems relatively OK. There are plenty of sources that extol its virtues, though, which is why I posted. Dr B is often detailed about these things. It'd be good to get his thoughts on MSM. That one has been doing the rounds on YT here and there, too...
the fittest older guy i ever met, was obsessed with bodybuilding and health, against smoking and alcohol, believed in eating alot of protien, but he shocked me how fit he was because he wasn't the smartest guy cause he was a bit punch drunk from being a boxer in his earlier life, and he done one cycle of peds when he was younger and done a bodybuilding competition, and after that was obsessed with bodybuilding, he would unload containers full of washing machines with us at the age of 57, that's 70-80kg above your head from the floor, 500 reps a day everyday, he would then have a few days of the week at gym where he would do workouts like your standard, bench press, squat, he didn't deadlift though, he only had a slight pain in his shoulder during the winter months probably his rotator cuff, and he would always be challenging us to push up competitions etc
This is a genuinely curious question, not an attack. So do you think all those people on the Keto and carnivore diets who have had such amazing success, by putting many diseases and auto-immune diseases and many other things into remission and some say cure, are going to drop dead in 10-15 years time with a heart attack? What about those who eat tremendous amounts of saturated fat and their blood work is very healthy, good triglyceride to HDL ratio and other markers?
They avoid UPF so of course that's good. No doubt they feel great short term. But with high LDL and low fiber, time will tell if their long term health will be good.
It seems that despite all the "evidence" it's not easy or advisable to generalize a specific diet across the entire population, as every organism behaves and responds differently to food and nutrition. There are many people to have healed from their ailments thanks to keto or carnivore diet. If they're feeling great and their blood checks are OK, it seems that it's working for them so they should keep going. Others, many of them already healthy haven't improved with those diets or have even got worse. In this case, it means they have different needs.
@@indiankid8601 I am aware they may be feeling better for the reason of leaving a bad diet behind but that's not what I asked, bear in mind their metabolic markers improved and can now be in a healthy range on a high saturated fat diet. What I asked though is: will they drop dead of heart attracts etc in the next 10-15 years? And my curiosity stems from if their metabolic markers are within a healthy range why would they be more inclined to keel over than another person who followed, say a Mediterranean diet for example?
An important question regarding carbohydrate is whether carbohydrate on its own is beneficial or harmful to health. It would be interesting to have a study comparing a low carb diet+ fibre and other supplement to make up short fall from low carb diet vs diet with complex carbohydrate.
”Protein restriction down to recommended levels is the only intervention I could find that slows down all the aging pathways.” /quote from the book How Not to Age by Dr Michael Greger
Slightly related to this topic on the best diet, I see that recent news article on a guy who received the ignoble award for debunking blue zones. It turns out the census data was all wrong.
Wow, this was really comprehensive and well structured! And best of all, it matches almost perfectly my prior beliefs! I'm left with a single question, however. While muscle strength is obviously related to muscle volume, is there a case to be made that you can have adequate strength with less volume, like endurance athletes? And thus be fine with a diet in the lower range of protein intake?
For what I understood looking at the cited sources, the studies show that muscular development peaks at 1.6 g/kg (+ strength training) in non-athletes, but also that 1.2 g/kg is still good enough.
But plant based proteins are lacking in lucine, how does that comply with maintaining strength and muscle? And whats wrong with eating good beef cooked at home (unprocessed and not with adde butter and oils ) ?
They are not lacking lucine. Just include a wide variety of plant-based protein sources and the whole amino acid profile will be covered. No need for animal protein
I'm personally skeptical that the effect of plant based protein substitution is independent of fiber and saturated fat intake. My suggestion is to use both. I eat a lot of legumes and use some plant based protein powder, but I also eat a lot of chicken, fish, and nonfat Greek yogurt which are all great sources of leucine.
@@SamplePerspectiveImporta-hq3ip you don't need chicken fish or yogurt to get leucine. This is based on the book Outlive by Peter Attia, just eat more of the diverse plant protein. You can even get yeast protein today with complete amino profile. No animal cruelty needed
The science was good. Much of the advice was good. Missing is the effects of Advanced Glycation End-products (AGEs). They are associated with every major disease of aging. And pizza is high in AGEs. AGEs are made as a result of high temperature exposure of the food, mechanical blending, or fermentation. They can also be made in the body when blood sugar is high. AGEs are Frankenstein molecules, where carbohydrate molecules bond with either protein or fat molecules, making these harmful molecules. AGEs can lodge themselves in the intercellular matrix, the spaces between cells. This stiffens tissues and also increases inflammation through the RAGE pathway. AGEs are also called glycotoxins. This is a big reason some diets are good or bad. Culturally, we tend to prepare things like zucchini differently than sausage. Though, zucchinis can be breaded and fried. We just tend not to cook them this way. We boil them, steam them or eat them raw, generally. And those ways are healthy. The ways food is prepared makes all the difference in the world. This is why fast food is poor for health. They nearly always use rapid cooking of the food, or it is blended in some way prior. There are a lot of things brought to high temperatures you may not consider. Things like roasted nuts, seeds, and nut and seed butters like peanut butter and almond butter. We want to avoid heat much above boiling water (100C). A little higher using steam is fine too. It is not necessarily the temperature setting. Of greatest concern is the temperature the food is raised to. "Cauliflower crust pizza" is a total fail. Take a look at the ingredients. I was suckered. I bought this stuff 6 months ago. Even tried to minimize heat and cheese browning. I felt terrible after eating this stuff. I was doing much better with my own workaround: A quality marinara with ordinary ingredients, with some basil in a bowl, added mozzarella cheese, covered and microwaved. Not too long. And the cheese should not touch the sides of the bowl. The marinara heats the cheese fairly evenly. We want to avoid any hardening and browning of the cheese. When I am microwaving that, I very lightly toast a piece of sourdough bread. Just so it has a little stiffness and is dry to the touch, no browning. I then put the heated cheese and marinara on the toast. Best is the melted cheese first, so sogginess is reduced. Mozzarella is relatively low in AGEs for a cheese. Cheddar is pretty high, and Parmesan is stratospheric high. Even though marinara is blended with a machine when they make it, the acid and the fact that there is not much protein or fat, results in very low AGEs. Peperoni is high in AGEs especially when browned in an oven. And yes, mice lived longer when their food had lower AGEs (median 15% longer, max 6% longer), and they had much better glucose, and lower RAGE in kidneys and liver. "Reduced Oxidant Stress and Extended Lifespan in Mice Exposed to a Low Glycotoxin Diet." And in humans AGEs are correlated with most diseases of aging, especially Alzheimer's, Diabetes, and Kidney Disease. The rise in diabetes was unlikely to be because of soda. We were all advised to cut down or quit drinking soda and other consumption of high fructose corn syrup. Americans listened. We went from consuming 62.5 lb of HFCS in 2000 to 36.7 lb per person, per year. This reduction had zero effect on obesity and diabetes rates. They continued to climb exactly as they had been. I am not saying soda and other HFCS drinks are good, just that they are not the cause of the obesity epidemic, the increase in diabetes and Alzheimer's rate increases. There was a large increase in Alzheimer's in 2013. I think we need to do some serious work to track that cause down.
Evidence suggests that chub mackerel might be a better choice than salmon. It is higher in omega-3s, and it is lower on the food chain, resulting in lower levels of mercury, PCBs, dioxins, and other pollutants.
getting 120 grs of protein daily from a vegan diet is next to impossible or your would be eating too much calories as density of protein is low even in best plant based sources.
@@shon7507 double that atleast. Protein methylation for most plant proteins (the ones you listed definetly) has not a 100% factor like meat. In fact it should be below 50% for most people. Peas and Soy are above 50% though.
I wonder if that would mean that the effects of TRT in older man would be more pronounced if they looked at it inside the context of a high protein low saturated fat diet + resistance training (compared to matched controls also doing resistance training + high protein low saturated fat intake, but no TRT, of course). As far as I'm aware, the current data on TRT is mixed both for negative and positive effects on overall health and all cause mortality in older man with "low" but non-hypogonodal levels of testosterone, but maybe its synergistic effect with resistance training + high protein could actually show a clear positive effect. It would be nice to see a clinical trial on that specific context.
At 12:45 You state that low carb diet didn't have the best effect yet, the chart you show didn't have any low carb diet on it. Just low fat. Your proof doesn't match your words.
One of your best videos Brad. Not only was this was cogent and convincingly presented, it made me think, through the right amount of cognitive dissonance
Good vid! In summary: whole food, plant based diet is the best. Keto, paleo, carnivore are the worst. Choose beans/legumes, whole grains, fresh fruits and vegetables. 🎉
Another excellent video, thank you! Salt intake seems to be very relative to your lifestyle. Athletes like runners might need much more than the average person. Did you come across studies that take such factors into account?
I am 86 years old, I have been on Keto for ten years. I lost an enormous amount of weight and feel great. Loads of unsaturated fats and plenty of protein, the odd glass of wine and chocolate. Feel and look great. It works for me.
you could always lose weight by eating a calorie deficit on any diet. Dont have to do keto for that. Although granted the food is more gross making u want to eat less of it.
@@proper2979 Calorie deficits can't control for hormonal imbalances. Or do you think eating an all sugar based diet, "but in a deficit", would leave your hormones properly balanced? You could also force yourself to eat rocks in order to eat unhealthy foods. Do you think if I told a starving person in an impoverished country he could eat a piece of cake, but only if he ate the rock first he wouldn't? Or do you just believe that what we eat doesn't matter as long as we lose weight? What about nutrients, sustainability, and overall feeling good?
Good video except from the conclusion about eating high protein. Is that really correct? I have followed a lot of different studies and by far the best “conclusion” about longevity we can make is through real life. For me The Blue Zones are extremely interesting. No manipulation, no short time study but real life. Over and over again from different places on earth. And they don’t eat high protein.
Evidence, or statistical data showing correlation that can infer opinions and guesswork? I don't remember seeing any cause and effect based evidence showing hard science, maybe I should re-watch the video.
Don't know about the studies dr Brad was referencing but in the Lyon diet heart study intervention group had more carbs than control group and up to 70% fewer heart attacks.
Great advice! Keep up the great work. You may want to consider interviewing Dr. Dean Ornish.
17 дней назад
Could you please make a video on food with pesticides and herbicides vs. organic food (with respect to health and longevity)? I would be interested in the available scientific findings.
Why isn't fibre okay for those with IBS? My GP wife recommends pysillium for my IBS. As for fruits, had a rash for the past few months, think its from histamine which some fruit have lots of (raspberries, strawberries, pineapple, etc). Pizza gives me the runs, regardless of contents (gluten free or not).
Isn't being on the vegan diet bad in the way where you are deficient in certain vitamins. People need supplementation because of the lack of animal protein. So can vegan really be one of the best?
Brad I wish you would reach out to two people, one is Bryan Johnson, and the second person is Charles Hoskinson. Bryan is doing some amazing protocol work with his DON’T DIE initiative. And Charles Hoskinson just launched a longevity clinic in Colorado, he is the founder of IOHK, who created the crypto Cardano.
2nd on the Bryan Johnson. However Charles is not vegan and thinks veganism is a cult (which it isn't). He eats meat, is fat, and won't stop eating bad stuff
I don't have much interest in what Bryan is doing TBH. N=1 experiments aren't particularly enthralling. Instead, I focus on what the preventative care clinical guidelines suggest, that are based on large human randomized controlled trials and meta-analyses
Meat has taurine in it unlike plant based protein. I would think that a high meat diet would beat a plant based protein diet, esp. as people age and manufacture less taurine themselves. Taurine has been shown to increase lifespan though. Seems counterintuitive
@indridcold4210 thankfully we have human outcome data with substitution analysis. I'll take that over isolating random nutrients and intuition. The scientific method is cool like that.
The human outcome data suggests that meat is worse for aging despite a little extra taurine. Health Outcome data is greater than mechanistic speculation.
Taurine is not an essential nutrient at all. There may be some evidence that it could be advantageous to supplement but the amount you wouldn't be able to get just in eating meat. And the benefits don't outweigh the risks of trying to get it from meat. So if there is a benefit a supplement would be better. And there are vegan supplements available for it.
Blaise V has made a very good video about you. I been on carnivore diet for the last 5 years eating high amounts of saturated fat and animal protein. Saying it is bad for us is totally wrong. Bad are processed sugars, processed foods, plant oils,....etc, not saturated fat and meat. Wake up.
