Other than the mess which they could've avoided; what has he really done wrong here? The crossed arms, disapproval, and the way the guys cower down is over the top. Its some friends watching a game.
"Women are bad and ruin the men's fun." Hollywood misogyny. Like how Seth Rogan's character's wife restricts his weekday guest privileges, which is a _totally_ normal, healthy thing for an adult to do to their spouse.
It's not necessarily that they're having fun, it's that Dupree at that point just made himself at home and invited people over without consulting either Molly or Carl. Inviting Neil over was one thing, but then ALL their coworkers who then used her grandmother's silverware? Honestly her NOT exploding at them shows serious restraint on her end.
