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Acidity: Crash Course Organic Chemistry #11 

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Acidity is a tricky concept, and it’s not always like how we see it in the movies. As organic chemists, we need to know how to predict the strength of weak acids and bases. In this episode of Crash Course Organic Chemistry, we’ll learn four key factors that we can use to predict relative acidity. This important tool will help us us to predict the products of chemical reactions.
Episode Sources:
Chen, J., Zhao, Y., Li, X. C., & Zhao, J. H. (2019). Pyridine alkaloids in the venom of imported fire ants. Journal of agricultural and food chemistry, 67(41), 11388-11395.
Everts, S. (2014). “An Ant’s Acid Antidote” Chemical and Engineering News, 92(9), 44-45.
Trummal, A., Lipping, L., Kaljurand, I., Koppel, I. A., & Leito, I. (2016). Acidity of strong acids in water and dimethyl sulfoxide. The Journal of Physical Chemistry A, 120(20), 3663-3669.
Series Sources:
Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018.
Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014.
Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012.
Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014.
Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012.
Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009.
McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016.
Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020.
Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013.
***
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2 сен 2020

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Комментарии : 162   
@arjunsinha4015
@arjunsinha4015 3 года назад
10/10 for thumbnail.
@torimallory9499
@torimallory9499 3 года назад
So True
@stephenparallox
@stephenparallox 3 года назад
Actually, I saw the thumbnail, mouse over it and saw three asian girls walking with back packs thru the woods, and my thought was, "this isn't going to end well"
@Noellexafael
@Noellexafael 3 года назад
This series is like the best thing ever, i just finished My 3rd semester of orga and its probably the class im doing the best in college and i still have some loop holes that this crash course is filling. Thanks for doing such an outstanding job.
@Baxtexx
@Baxtexx 3 года назад
Depends I guess. I only understand maybe 10% of the content in this series.
@Noellexafael
@Noellexafael 3 года назад
@@Baxtexx organic chemistry is like a language, u need to practice a good bit to memorize its rules and structures but once you do things gets much easier do just keep practicing and you will get there eventually.
@dratelectasis
@dratelectasis 3 года назад
I'm a doctor who just forgot a lot of these basics. Thanks for the refresher!
@yoursevershahriza1494
@yoursevershahriza1494 3 года назад
*The Editor deserve the Oscar* 💓🙏
@draheim90
@draheim90 3 года назад
I’m glad I stuck with psychology as a career choice.
@daviddemuth6075
@daviddemuth6075 3 года назад
Wow this never really made as much sense to me in school as it did watching the animation is listening to you teach thank you so much for brightening my day
@snapcracklepops
@snapcracklepops 3 года назад
Ah, this takes me back to the first class to ever make most of the class laugh when seeing the test because it was insanely hard; I dunno what the second semester teacher was thinking. I remember having to name molecules shaped like animals (eg. frogs). Good stuff!
@aarondwyer6591
@aarondwyer6591 Год назад
These are some of the best O-Chem videos. Thank you!
@EthanSalter3
@EthanSalter3 3 года назад
Best way to remember is through Cardio C - Charge (Positive ion stabilizes loss) A - Atom identity (Large electronegative atom stabilizes loss) R - Resonance D I - Dipole Induction O - Orbital (S character stabilizes loss)
@sinaabedini7487
@sinaabedini7487 3 года назад
Beautifully explained. wish this course started a year sooner cause i already passed OC. But it's still a great sources for refreshing the memory. definitely recommend to every science student👌
@khier-eddinehennaoui9783
@khier-eddinehennaoui9783 3 года назад
This channel is just a blessing for chemical engineering students .
@quinnpuffer7901
@quinnpuffer7901 9 месяцев назад
This video was crazy helpful and explained things very very well. Thank you!
@benesgro4531
@benesgro4531 3 года назад
Bravo! This is so well done
@kayliehansen4831
@kayliehansen4831 3 года назад
I'm writing my summary sheets for my upcoming test 1. The two things I was fuzzy on were inductive affect and intermolecular forces. Thank you!
@scottmerritt9877
@scottmerritt9877 3 года назад
This is definitely an excellent presentation. Thank you.
@vanessaaitkensilva4279
@vanessaaitkensilva4279 3 года назад
I had some problems explaining s character effect on acidity to students, so this video was super helpfull, thank u!!!!
@SohilRathi
@SohilRathi 3 года назад
Hello, Crash Course Videos have always been great, interesting, and fun to watch all at the same time! I have watched all the crash course science playlists and learned a lot from them! I would really appreciate it if you made a crash course series on Earth Science! Thanks!
@justinmular4863
@justinmular4863 3 года назад
I too would really benefit from this!
@Painted_Owl
@Painted_Owl 3 года назад
I don't think I've ever seen a Crash Course that didn't have Hank, or his brother. A welcome change 👌
@haybhee5294
@haybhee5294 3 года назад
😯 A big topic in a nutshell 💯
@kl1970
@kl1970 3 года назад
Best freshup for a first semester recap exam. Thanks friend :)
@kocengineering769
@kocengineering769 3 года назад
Mam Thanks a lot I love ur explaining way so much I need more frequent videos chemistry I just love this show very much Kudos very good job and info 😇😇😇😇😇😇🙏🙏🙏🙏🙏🙏👍👍👍👍👍👍😊😊😊😊😊😊
@Sports590
@Sports590 3 года назад
Ma'am looks Stunning as Always 😍😍😍
@gre3nishsinx0Rgold4
@gre3nishsinx0Rgold4 3 года назад
I always get so focus on this that, it shocks me everytime I get to the end.
@senahoroz
@senahoroz 3 года назад
when I see xenomorphs I click
@nikhildeshmukh6851
@nikhildeshmukh6851 3 года назад
Alein isolation Was a nightmare Me everytime while playing 😨😨😨😨 And that scary footsteps sound.
@FootLettuce
@FootLettuce 3 года назад
Just like the last time with Ruby and Sapphire
@troy6377
@troy6377 3 года назад
Same
@folderfolderson7042
@folderfolderson7042 3 года назад
Sena Horoz awww thanks
@Xballawanaka
@Xballawanaka 3 года назад
That alien thumbnail is Def a good idea, I didn't even know there was an organic chemistry crash course, you should def use it again
@ibawanhunlytan8606
@ibawanhunlytan8606 3 года назад
congrats on 11M!
@OldMovieRob
@OldMovieRob 3 года назад
I was following it all fine until it got into the chemistry part.
@drakesmith471
@drakesmith471 3 года назад
ARIO!!!
@Epinardscaramel
@Epinardscaramel 3 года назад
Lol, same
@ThatViolistKatie
@ThatViolistKatie 3 года назад
Wish I had this when I was taking Ochem! Oh well I have it now for the MCAT 😂
@abrakadabra1682
@abrakadabra1682 3 года назад
This needs a longer episode
@gekostar22
@gekostar22 3 года назад
would have liked to see some theory crafting on what kind of acid, or if its possible, that the xenomorphs had.
@alexaRICHI30
@alexaRICHI30 3 года назад
Very interesting!
@manalmanal0
@manalmanal0 3 года назад
I really wish you make crash course architecture. I need some questions answered about architecture and I really enjoy watching crash courses.
@torimallory9499
@torimallory9499 3 года назад
I love your channel and videos😍
@naiyakatoch
@naiyakatoch 3 года назад
I just like her way of teaching 💕💕
@InspirationFromThePast
@InspirationFromThePast 3 года назад
Got caught by Alien picture, but in the end actually learn something thank you for a very informative video.
@danteshammer
@danteshammer 3 года назад
YES! I completely understand all of those words she used. Do you concur fellow scientists?!
@allertonoff4
@allertonoff4 3 года назад
erm .. my mind is oriented to filter out information and find paradigms and substructures .. neat job there my friends ! x;]
@medicalbiochemistry_
@medicalbiochemistry_ 3 года назад
Well explained
@alfiyamulla
@alfiyamulla 3 года назад
Amazing 🤩 content
@scottvandesand9366
@scottvandesand9366 3 года назад
John greens as old as my dad, and I find that WEIRD
@samuelpaulini
@samuelpaulini 3 года назад
Well, the predator acid should actually be a weak acid so as to not to passivise the iron forming a protective oxide. It might just be super hot at have some other cathalitic properties.
@Labgorgremlin
@Labgorgremlin 3 года назад
The strength of an acid (how easily it can lose a proton) is not directly linked with its oxidizing capability. Hydrogen iodide is a very strong acid but is a weaker oxidizing agent than nitric acid.
@kl1970
@kl1970 3 года назад
@@Labgorgremlin nitric acid creats NO3- ions that react great in acidic invironments
@EstebanGuzmanV
@EstebanGuzmanV 3 года назад
With that thumbnail, would it be cool to see some of this on the video
@tamara293
@tamara293 3 года назад
You made an app?? Thank you so much 🥺 Damn my grades are gonna be really good regardeless of quarantine
@kgigjdjsuazhzhsnjszs
@kgigjdjsuazhzhsnjszs 3 года назад
Is there a video explaining the same basics for basicity? Or is it just that weaker acids are stronger (conjugate) bases?
@ljuc
@ljuc 3 года назад
Yes
@kingali1606
@kingali1606 3 года назад
And to think there are probably some Xenomorphs roaming a planet in the universe somewhere right now. The universe is so vast it's mind-boggling sometimes.
@neontetra1000
@neontetra1000 3 года назад
Whooosh!.
@saumypks
@saumypks 3 года назад
I can't wait to download the app!!! Exept here it's midnight and I hav to sleep.😭
@diegonayalazo
@diegonayalazo 3 года назад
Gracias
@rhoddryice5412
@rhoddryice5412 3 года назад
I hope I finally will learn what molecular acid is.
@hueychan6907
@hueychan6907 3 года назад
I am a chemistry major. Why am I watching this😂? Anyway nice episode
@ChadWilson
@ChadWilson 3 года назад
Because learning places you into an excited state?
@dogvetusa
@dogvetusa 3 года назад
double checking factuality?
@lloydlim1055
@lloydlim1055 3 года назад
I am buisness student, so don't worry it's not weird.
@josenellandrewtumulak2400
@josenellandrewtumulak2400 3 года назад
Dope
@imaginecloudsxo7987
@imaginecloudsxo7987 3 года назад
Ohwell I would've needed that video 5 weeks ago for my final chemistry exam. Nevertheless I passed them 🥳😊
@samuelzev4076
@samuelzev4076 3 года назад
Because the opening starts with a sci-fi reference, we should also discuss predator’s blue acid that can even melt things under water, any explanation for that?
@juliusbodino6395
@juliusbodino6395 3 года назад
Bat ngayon ka lang naing content. HAHAHA Barely need this, thanks :)
@ankithsmenon1935
@ankithsmenon1935 3 года назад
Can u please give priority to organic chemistry it's really very helpful
@rossfriedman6570
@rossfriedman6570 Год назад
Does joules/ mole include any powerful acid/ base reactions something can cause?
@ianjonas
@ianjonas 3 года назад
key thing i learned today: you take the tent, another friend takes the cooking gear, and I take all the food.
@matthewsmusicshop
@matthewsmusicshop 3 года назад
Cool
@gg3675
@gg3675 3 года назад
I can keep track of each of these factors individually, but when we're combing all four I start to get lost in the sauce.
@easyadventurer
@easyadventurer 3 года назад
Uh huh, uh huh, I understood some of those words 🙃
@ronaldfigueroa932
@ronaldfigueroa932 3 года назад
I find more interesting than acid ,the ability to create a defense mechanism that contains it, In addition xenomorph blood is a potent molecular acid that contains within its blood, a highly corrosive substance
@laurawalker05
@laurawalker05 3 года назад
wow 10/10
@SciFactsYT118
@SciFactsYT118 3 года назад
Completely random fact: The human nose can remember 50,000 different scents. -SciFacts
@way2nasty533
@way2nasty533 3 года назад
I wanna smell you
@fernaburna
@fernaburna 3 года назад
hiroshima- sama 😳
@g3heathen209
@g3heathen209 3 года назад
The nose can't remember anything, it has no brain. Rather the brain can interpret singals from the nose and detect all those diferent scents. Still a remarkable feat.
@j.stonehouse5004
@j.stonehouse5004 3 года назад
@@g3heathen209 I came here to say that
@sayedadnan6419
@sayedadnan6419 3 года назад
@@j.stonehouse5004 me too 😂
@StudySessionYT
@StudySessionYT 3 года назад
Quality thumbnail lol
@XxHATE1xX
@XxHATE1xX 3 года назад
I love you
@BartJBols
@BartJBols 3 года назад
Xenomorphs acid could very well be extremely oxidising, causing it to eat through steel. The acid would dissolve rust, the oxidiser would turn steel into rust. As these processes heat up the compounds and the steel, things escalate out of control. The part that kills humans is just the acidic element.
@JAnaya91
@JAnaya91 3 года назад
That's some strong acid! Madam.
@ShauryaSingh-ts2oc
@ShauryaSingh-ts2oc 3 года назад
7:05 But negative charges are more stable on more electronegative atoms I think? Isn't that a factor to consider here? And what about sp2-3p overlaps being weaker than sp2-2p in case of carbon (where sp2 is formed from 2nd shell )??
@blackout995
@blackout995 3 года назад
The bigger the atom, the more space to keep electrons, and thus the less intra-electron repulsion there is (which increases stability, and thus inclination to ionize, making it a stronger acid). HF is a weak acid even if F is the most electronegative element, because fluoride is not as stable as Cl- or I-. Similarly, oxygen can have a lot of difficulty retaining a negative charge without resonance, while larger elements might not. Thus, Ph-Sh is a better acid than Ph-Oh simply because S is bigger, thus more tolerant of losing that H+. As for your bonding orbitals, it comes down to polarizability. You're definitely right that the 3P should be less stable given its size, but depending on the bonding, it might not matter enough to vastly reduce the Ka.
@rossadams7946
@rossadams7946 3 года назад
Just to add on to what Koda said, you also have the fact that the bond will be weaker due to the poorer overlap of orbitals and due to the lower electronegativity of the S atom will lead to the bond to have less ionic character.
@thecosmicpower4451
@thecosmicpower4451 3 года назад
I am studying online everything going on smoothly but I don't know why I came here I see suggestions and click
@MaessyChan
@MaessyChan 3 года назад
Oh! New video from Crash Course about acidity! But I understand *NOTHING!* 😳
@sickoandlunatic1238
@sickoandlunatic1238 3 года назад
can you upload electronic crash coruse?
@nabilm6116
@nabilm6116 3 года назад
How do you collaborate with people to make these video
@TheAlderFalder
@TheAlderFalder 3 года назад
Without the thumbnail I wouldn’t know what it’s about.
@halfgallon674
@halfgallon674 3 года назад
Uh oh if I watch these it’s gonna get me confused w basic chem rn
@jheadley635
@jheadley635 3 года назад
This video still doesn't explain why strong acids eat through things in the first place. Why does a molecule losing a proton cause it to eat through something?
@cheema9410
@cheema9410 3 года назад
Mam please answer me the following two questions. 1.what happens when methylcyclopropene is heated with HBr? 2. Although Nitrogen is more electronegative than carbon ,the direction of the dipole moment is towards the ring? Plz plz answer me.......plz
@rossadams7946
@rossadams7946 3 года назад
1 - Assuming the compound to be 1-methylcyclopropene (numbering is important) then it'll be brominated by the H-Br. First the pi electrons of the alkene double bond will bond with the H in H-Br, breaking the H-Br bonding and forming a bromide ion. The hydrogen will be bonded to the secondary carbon. This is because this will lead to the formation of a tertiary carbocation which is more stable. The bromide ion will then form a bond with the tertiary carbocation. 2 - The dipole moment is towards the ring as the nitrogen may donate its lonepair of electrons into the ring, forming three different resonance structures, all in which the nitrogen will have a positive charge. Therefore the nitrogen has a partial positive charge and the ortho & para carbons a partial positive charge. Thus, the dipole moment is towards the ring.
@cheema9410
@cheema9410 3 года назад
@@rossadams7946 1.if methylcyclopropane is haeted with HBr then what happened? Plz answer me
@rossadams7946
@rossadams7946 3 года назад
@@cheema9410 If methylcyclopropane was heated with HBr then nothing should really happen. There isn't any way the carbons could perform a nucleophilic attack of the H in H-Br.
@cheema9410
@cheema9410 3 года назад
@@rossadams7946 Thanks alot ♥️🌞
@user-pj4tc7ee3c
@user-pj4tc7ee3c 6 месяцев назад
2:04 - 2:07 1:54 - 1:57 can any one explain how she didn't just contradict her self
@ReidMerrill
@ReidMerrill 3 года назад
PKA RSK!
@suryaprasad2558
@suryaprasad2558 3 года назад
hank green
@AbhishekKumar-jj6ss
@AbhishekKumar-jj6ss 3 года назад
That thumbnail is frieza form in bdz
@vasutyagi2127
@vasutyagi2127 3 года назад
Your app doesn't work
@EricaShand
@EricaShand 3 года назад
oh, okay
@folderfolderson7042
@folderfolderson7042 3 года назад
I’m a simple xenomorph when I see a xenomorph I click
@stza16
@stza16 3 года назад
Me brain be growin
@Xyz10721
@Xyz10721 3 года назад
I am now suffering from acidity and indigestion
@nikhildeshmukh6851
@nikhildeshmukh6851 3 года назад
Get ready to fart💨 A boom! boom!
@vegasmind82
@vegasmind82 3 года назад
Xeno4life
@christianandrews7764
@christianandrews7764 3 года назад
Crash course viewers can handle the Lewis Acid/Base definition
@duckforceone
@duckforceone 3 года назад
Soooo was hoping for more alien stuff. But was left sadly dissapointed
@arkodeepmaitra
@arkodeepmaitra 3 года назад
Will Hank Green teach us math ?
@Defelade
@Defelade 3 года назад
What I need to know is..can my laptop be used to defend myself from an alien acid attack?
@thomasgarrett4759
@thomasgarrett4759 3 года назад
Does this actually make sense to anyone
@ProfessorOzone
@ProfessorOzone 3 года назад
Man! I couldn't watch the whole thing. Can a strong molecular acid eat through a space ship or not?
@rizdalegend
@rizdalegend 3 года назад
I don't understand anything after watching this
@maksphoto78
@maksphoto78 3 года назад
Fats and oils are acids too, right?
@rossadams7946
@rossadams7946 3 года назад
Most animal fats are comprised of triacylglycerides (TAGs), these TAGs are esters derived from glycerol and three fatty acids. So, the fat itself is not acidic (I mean everything is somewhat acidic but in the general sense it's not) but the ester bonds in these TAGs may be hydrolysed to yield the free fatty acids. These free fatty acids are actually used as biomakers in archaeology. The term oil defines a large range of non polar compounds which are hydrophobic, and thus are all likely to be not very acidic - However, fatty acids are found in organic oils so...
@IAmJustAPerson-
@IAmJustAPerson- 3 года назад
;P #lovexenomorphs
@folderfolderson7042
@folderfolderson7042 3 года назад
StarShapes ya
@aurora8620
@aurora8620 3 года назад
When did I subscribe
@iimmm1
@iimmm1 3 года назад
Too fast to follow!!!
@SuperAndrewlove
@SuperAndrewlove 3 года назад
Try watching at half speed then! 😊
@abhishekbhowmik3456
@abhishekbhowmik3456 3 года назад
Came here for the thumbnail
@nafnist
@nafnist 3 года назад
Thought it was called alkaline
@syrupstarlet
@syrupstarlet 3 года назад
2 hours and only 4000 views. Example of how nobody clicks on these until they’re assigned to us by our teachers.
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