Alzheimer's - Diabetes of the Brain Caused by Fructose? 

Just to think that Alzheimer patients are put into institutions that feed them white sandwiches, starches and sugary fruit juices - a diet that not only accelerates the disease but also shortens their life. As a society which aspires to be humane and caring, we have quite a long to go.

My dad fixed my mother's coffee every morning, and he put 5 heaping sugars in her coffee every morning. My mom died at 80 from Alzheimer’s. My mom was a small woman. Dad was almost 3 years older than mom, and he died from Alzheimer’s at 86. I'm hopeful that I won't die from Alzheimer’s since I stopped sugar and grains for the most part.

Glad to see you establishment doctors finally STARTING to catch up with the holistic (functional medicine doctors) who have preached for decades that the amount of highly processed sugars we are consuming since the 70's is responsible for all the chronic diseases that are epidemic in western societies.

The head of the cardiac department at a major health company told me that we could close 95% of the hospitals in this country if people would stop putting garbage in their bodies. Btw im 63 no health issues and perfect bloodwork numbers. Ive been off sugar, processed foods, sodas, alcohol and most carbs for 30 years. Its not that hard to eat right once you get accustomed to it. Most groceries have their produce, meat, dairy and frozen veggies around the perimeter of the store. Buy as little as possible out on the middle aisles and youll be ok.

Correction. It's not the hamburger. It's the bun. The sweet relish. The accompanying french fries.

This is very fascinating. When I used to be a vegan my mind was always in a fog. I couldn’t quite think clearly. Then when I changed my diet and added eggs and dairy I felt better. Eventually I started eating meats and eventually converted back to the standard American diet. Once again, my brain was always in the fog. I felt more irritable and sluggish than ever. I slowly started to cut out sugar, carbs, and even some veggies. I felt more alert, and no sluggishness. Now I’m 100% carnivore diet and I have never felt so good in my life. Especially my mental clarity is at where it should be, for a 28 year old. I do believe diet really plays a huge role in our overall health.

I utterly disagree with you regarding the salt. If you're eating properly, you will require salt. If you don't consume salt you will end up with cramps. If you eat too much salt you will get thirsty. Also if you drink a glass of water before a meal, you're just diluting the acid in your stomach that should be digesting your food.

Johnson never said a thing about "fat", so why did the interviewer point to it as a problem. It should be blatantly obvious if you want to reduce sugar and other carbs the best way to do that is to eat more healthy and satiating fat. Fat and cholesterol provides building material for nervous tissue and the hormones that contol our health. Fat satiates and provices anti-inflamatory ketones.

Here is a ChatGPT summary: - We are facing a serious crisis with Alzheimer's as baby boomers age into their 80s and 90s. - An article in the American Journal of Clinical Nutrition suggests that Alzheimer's could be the result of our bodies going wrong in an evolutionary survival mechanism. - The key villain is fructose, a form of sugar found in high fructose corn syrup and fruits. - Fructose tricks the body into thinking it's hungry and reduces the energy we actively use. - This leads to neuroinflammation and starves the brain of energy. - Amyloid plaques and tau tangles are a defensive mechanism the brain is putting forward to protect itself. - Eating excessive amounts of sugar, high fructose corn syrup, and high glycemic carbs can increase the risk of Alzheimer's. - Alzheimer's is a potential epidemic and David Perlmutter, Dale Bredesen, and Maria Nagel are authors researching the topic. - Fructose consumption can lead to a decrease in blood supply to certain regions of the brain, such as the cortex and hippocampus, which are involved in self-control. - At the same time, other areas of the brain, such as the visual cortex and anterior cingulate, increase in blood flow. - This matches the areas affected by Alzheimer's, suggesting that fructose consumption may be a contributing factor. - Low sugar, low carb diets, keto diets, and intermittent fasting can help to reduce the effects of fructose and potentially prevent Alzheimer's.

You interview very well with only useful interjections for clarification. Thanks.

My diet is mainly fruits and vegetables. I’m super healthy, no chronic disease, I’m sleeping great, great memory, super active, i practice calisthenics and lots of hiking. I never felt better, I eat organic, gluten free, I don’t eat any refined sugar.

Wow, this is a hugely compelling presentation.

Don’t cut back on salt, but get good salt like Redmond

Thank you, I needed that.

When they say something "COULD" be the problem, it means they don't know.

I had to give up fruit, as I noticed with it being singularly what I ate in the morning for breakfast, within a half hour, I would be sunk low and ready for a nap. The sugars of the fruit affected me, so they weren't difficult to give up.

We are still hunters gatherers metabolisticly talking, we just don t live accordingly, we eat sugar all days long.

Super interesting, thank you

Alzheimer's is preventable. We should just avoid carbohydrates as much as possible. I think the average good thinker already is aware of this. Mostly grains and sugar.

I stopped eating sugar, including fructose. I consume as little as possible.

Great information 👍 thank you!

My mother died of Alzheimers and she ate very little as in she had a simple “ healthy “ diet. She hardly consumed any fruit and had a very low sugar intake ? I understand that these matters are complex - every step forward is great against this terrible disease.

Baby boomers are not aging into their 80's and 90's at the moment. The oldest baby boomers were born in 1946, and are presently 77.

Just one word: Inflammation.

Remember as mentioned, high glycaemic index foods are refined carbohydrates eg flour, white rice, white bread, pasta. These are broken down in the body in the same way as the table sugar in our food. Surprisingly, small slice of white bread has the energy equivalence of about 2 teaspoons of sugar.

Excessive fructose intake didn't happen for the vast majority of people prior to the early 20th century. High fructose corn syrup didn't exist until about 45 or so years ago. If the fructose hypothesis is right, we should see fewer Alzheimer's patients prior to the wide availability of fructose in the modern world.

No mention was given to the ability of the mitochondria to change their energy source from glucose to ketones. Ketones are able to cross the blood brain barrier and provide additional energy for the mitochondria in areas that need it most…. Being able to achieve a glucose ketone index of 1, in itself indicates that the Insulin level will be low, and allow the body to produce short chain fatty acids from the fat stores. I was interested to learn that some areas of the brain need it, and some areas don’t.

My Mom has dementia. That comes first. I’m hoping it doesn’t go to Alzheimer’s. She ate sugar and flour garbage food for years.

Fruits and carrots have been cultivated for many decades now to be sweeter. When I was a child an apple tasted like an apple, it was sweet but it had a apple flavor. Now apples taste like sugar bombs! I'm 61.

Amazing!!!! Gonna get his book!!!! Thank you….

Humans living in tropical climates have been eating high fructose diets for thousands of years. Fruit is not the enemy. What has changed in the last 50-80 years. fruit is the same. I a vegetarian has eaten at least 4 to 6 pieces of fruit a day for the last 50 years. I'm healthy no sign of diabetes. Fruit is not a problem. Whole foods are not a problem. Processed foods are the problem.

Nice discussion but please , don't say don't eat hamburger, say , don't eat the bun and potatoes that come with the actual hamburger.

Above all remember to consume adequate coconut oil (MCT OIL, ketones) to provide brain energy and minimize fruit intake.

I.f plus fasting to reset plus ketosis plus salt to taste rather than processed foods poisoned with salt and sugar. Avoid any drinks that mimic soda and have aspartame. If you have the odd treat at holiday or birthday so be it. As long as it doesn't slide you down the slippery processed sugary slope. Also I find I eat meat which can be expensive but not nearly as expensive as junk plus health costs. Great video well explained . Type 3 diabetics are growing in numbers so it makes sense to try and avoid becoming a statistic. 😊

You can regrow your brain but you can't necessarily grow back circuits that have been totally lost. First you have to feed the brain. It will have lost to ability to run on sugar but ketones from broken down fats are actually the preferred food for the brain. Brain exercises that involve controlled motion and balance will get the brain to grow,.

Does Richard J. Johnson, M.D., have a book . Fascinating report, my wife has early signs,

Hey' LEE KELSO you look pro and very healthy... Like it 😊

Maybe with juice, but not as whole fruit

Consuming fructose in high quantities from ORGANIC fruits will prevent neurological diseases. Highly processes sugars like corn syrup, consumed in high quantities, will create neurological diseases.

I’m not vegan nor vegetarian, but I consume fruit regularly fruit as my grandpas did, they never suffered any medical condition even at their 90’s. Seasonal and local fruit is packed with electrolytes and minerals, most important micro nutrients.

The problem here does not seem to be the fructose in itself. If you eat like a bear, be prepared to go into hibernation like one. An extended period where your body feeds on stored energy. Knowing when, what and why you eat is the reason you're going to stay in health or not, all things being equal.

Good food for brain and refraining shrinking

Please let your guest talk without interrupting them. Your interjections didn't help. Ask them questions or provide your own imput after they complete their thought...thanks. This is a great video.

perhaps our bodies need to eat the foods in season, as the farmer gets more busy in spring gradually until the beginning winter berry's and fruits are more plentiful, yet mostly the farmers energy needs also rise until the crops are off, burning calories, and also eating fresh fruits with live enzymes. we make the mistake of trying to heat process or freeze fruit for winter in large amounts and where now the fructose has no enzymes to digest and when people spend more time indoors, instead our winter diets change for what is in season, like the old ways we ate less meat and fat in summer because we did not havre refrigeration. but as soon as temperatures are below freezing is when the livestock was processed, or farmers or pioneers whent hunting, then ice fishing in the middle of the winter. by the time of the end of February most apple storage ran out, and perhaps beginning of march we starved, or simply fasted. the problem of agriculture now is we try and process the fruits, destroying the enzymes and other properties, but also making the fructose more available all year. and also now farmers sit on tractors getting little exercise. where once the excess fruit was fed to the livestock, chickens and ducks. as we could only can so many glass jars of fruit where sadly that practice also added extra sugar.

This hypothesis seems to make a lot of sense. I would recommend the book on mitochondria by Dr. Lee Know, too. The same thing causing Alzheimer's is also causing Parkinson's and MS. I would say that while fructose and sugar makes sense, he needs to expand on exactly how salt is also a culprit. Were bears loading up on salt when it was time to hibernate? He just kind of threw that in there without much to back it up.

“Inexpensive things ( high fructose food) that we’ve come to love.” It’s the only choice in 99% of locations when travelling in the US, it’s practically impossible to eat well in the US when travelling and at the average persons home. Add to that that the FDA tells you a balanced diet is what industry can make on an industrialised scale and you have the fattest people on earth whose brain function has been seriously diminished because of their diet, welcome to Merica.

I am from India. I don't eat any processed food as in the US. If we should not rice, wheat, fruits , .....what else to eat? Please guide us.What food we should eat to be without disease

So they are saying to drink water before you eat, to help, which really dilutes Hal in the stomach which is necessary for digestion??

I highly recommend Dr Dale Bredesen's books on stopping AD and he also has a new book about "survivors" who have overcome AD with diet, exercise, and supplements. It's super inspiring!

Come on...everything I read about Alzheimer's buries these unpleasant facts, alcohol use, tobacco use and obesity are highly linked to incidence. But those are hard to change and no one wants to be judged. Blame fruit! So much easier.

high fructose corn syrup You already connected Alzheimers to sodas. I suggest manufacturers of food products use it partly because it is easier to use in baking like in sodas but also because it appears independently in the label so it LOOKS like there is less sugar in the product.

what are high salt & sugars diets ?

Another nail in the coffin of ultraprocessed food

But my friend has alzheimers, and for years previously she was self-managing a seizure disorder because she had read that sugar was a risk factor for seizures, so she had cut sugar out of her diet almost completely.

Seed oils?

What if you have a craving for oranges, like eating three or four a day, plus say a few tangerines.. Would you be getting too much fructose?

Dr Johnson stated that salty foods can lead to Alzheimers. Really? Please explain. Ta.

I wonder if the ‘high salt diet’ that he says causes this condition (along with high fructose and sugar foods) is applicable on a very low to no carb diet.

Every body and blood type may need different diet

@ 17 to 20 min - why Alzheimer's affects temperal loves more than others.

5 🌟

10:27 amolyid plaques usually done with brain biopsy, no?! How are you monitoring this? 😮

I agree with everything however, fruit is not the problem at all

The possible solution is go on either the Keto or carnivore diets. And look into statins.

While I appreciate this discussion it frustrates me to hear it veer off point a bit @ ~15:50-ish when they lump “hamburger” in with the sugar & carbs. It’s the bun, the seed oils used in cooking fast food type burgers and not the saturated animal fats that are the problems They then again use the word ‘fat’ without nuance between saturated & un-saturated A century of ketogenic research has shown the effectiveness of fat as a primary dietary component *when it comprises 80-ish percent* and carbs are restricted to 15-20% of energy needs-i.e. low-carb + high [saturated] fat But, I *am* glad we are learning about the sugar-alzheimers link 👍

❤❤ridiculous really

We were hunter, gatherers, millions of years ago? Astonishing

Ted Naiman has shown its the protein that keeps you lean. What makes you fat is the energy toxicity from either excess carbs or fats. The leanest and healthiest people eat appropriate amounts of protein daily. Think about it, what are you gonna feed a end stage diabetic if they are starving. You wouldn’t feed them more carbs and certainly not a piece of lard. You feed them lean meats. Protein is what increases insulin sensitivity. Thats what will save their life.

Hamburgers? Let's please point out that it's the bun that's the problem, not the meat.

8:48

that is lie. american cardiologist associations saying coconut oil is bad for you . because they didnt got kickbacks.

Is this funded by the meat and dairy industries?

What about juicing organic Vegetables with fruits so we can stand the vegetable juice

OH YES THOSE TOXIC FOODS NEAR TO ELIMINATED OR RARELY EATEN ! No toxic grains No fruits No potatoes Works for me !

Fructose is good for diabetic or not clearly conversation with us

Fat generates fuel??? Nope. Fat is a fuel that generates heat.

#HealthCallRadioHour This question is serious. Not joking. Does expensive fructose’s health benefits outweigh the ill effects? Say in the form of the high-grades of mono-pollen raw Manuka honey from New Zealand? Or have I been subsidizing an expensive path to Alzheimer’s?

So no more fruits too?

23 minutes in they first mention fruits are not bad.

We should stop eating anything.

This hypothesis is problematic and flies in the face of scientific evidence that the Standard American Diet (high saturated fat) drives endotoxemia in the blood stream that then ends up inside amyloid plaque in the brain.

It's not that simple, just blaming fructose. There are many decades long Frutarians in perfect health with no dementia whatsoever. It's the fat blocking the insulin receptors that's a problem, leading to insuin resistance. You can eat a high fat diet, or you can eat a high glucose (fructose and/or sugar) diet, but not both at the same time.

It's so hard to follow him

Fructose is Fructose. If you are already diabetic best is zero fructose

The answer is a carnivore diet. Its the ultimate.

What didn’t he mention a vegan diet or a chicken and veggie diet 🤔

Nonsense. Glucose, fructose, dextrose, sucrose, levulose, maltose. .

How does this fit with the many studies that showed that diets with and without sugar if calories equated, have exact same results? If fructose would cause a higher percentage to be converted into fat while reducing available energy generation this wouldn't be possible.

Fresh fruits and vegetables are the best nutrition!

This guy always asks at the worst time and pretty irrelevant questions. The researcher could not make a point without useless disturbance.

Let the man finish his sentences, christ almighty!!

Might be time to break the power grid, cut down the power poles with a 40 volt battery powered chainsaw, cut the poles half way through the wind will finish it, silent and easy, no electricity no cameras no government, no AI and no data centers

These guys admit that the aren’t experts in this area. What a waste of time to watch this

Think about this > There is more Sugar on Earth than DIRT. Which means EVERYONE'S surrounded by it and it seems like EVERYONE has Alzheimer's etc. etc . Every person has this ONE thing in common. Ponder silently.

⚠️ The Hunter/Gathers All died from Diabetes. 😅😅😅

990lk

Hippocrates : "All disease begins in the Gut".

I only eat meat and animal fats. Zero csrbs, zero fruits, zero veggies. Well correction.. sometimes I drink whole milk, and some half and half. But that is maybe 3 to 5 grams here and there. My health has never been better.. my BO is very low.. i have lost so much weight. My gut is gone. Triglycerides have been about 55 to 54. Hdl about 75 or highr. I’m probably gonna be the worst candidate for alzheimers disease.

Sounds like another low carb cult. Insulin resistance is way more complex than this overly simplistic fructose hypothesis. What about the 5 blue zones population longevity? What about the Okinawans that get most of their energy from tubers?

The brain does not use Fructose. Biochemistry 101