Ubiquitin and the immune system
In most living organisms, the ubiquitin-proteasome system is responsible for the degradation of proteins, either because they're damaged or they reach the end of their life span. Ubiquitin marks a protein for elimination. Alterations in this process are responsible for many human diseases. Dr Benedikt Kessler studies the role of deubiquitylating enzymes that remove ubiquitin from substrate proteins.
Biomarkers
Biomarkers are molecular features that give us clues about underlying biological processes. They are typically used to monitoring a disease or predicting the outcome of a treatment. Modern analytical equipment allows us to measure thousands of molecules at the same time. This technology will accelerate the discovery of more accurate biomarkers, with the aim to improve medical diagnosis and treatment.
9 июл 2024
