BERBERINE - Amazing Benefits? or Worthless? 

Nope 👎! Your imaginary friend had nothing to do with anything. 😳

to avoid stroke, avoid seed oils like corn, soy, canola, etc. all of them !! olive oil is fine but use it very very scantily. avoid sugar, alcohol, coffee, and DONT fry your food! eat mostly raw fruit n raw veggies, and bake or roast your meats, dont fry them.

Fantastic Heather! Very exciting! Thanks for watching.

where did you get your berberine?

@@Garden-Resell-Thrifts, I've seen it at various stores, but I ordered it off Amazon along with the other supplements except nmn which I had to get from my local health food store. It's hard to pick out each one's effects, but I've accomplished a ton in the short time I've been on the regime. My primary care doctor was seriously impressed when she saw me a couple weeks ago.

I was dx with MS in ‘07, recently pre diabetes. I’m buying Berberine tomorrow and am hopeful, with comments like yours, in seeing positive results.

@@Krise343 Best of luck! My daughter was over yesterday and commented how long I had been so healthy since I began the supplements I'm taking. I think because my digestive system is so sensitive, I avoid a lot of foods with important nutrients like wheat which I can't have at all and dairy and meat which make my stomach hurt causing me to eat very little of them. So I had to figure out what I was missing and get it that way. Since I wrote this a bit over a month ago, my arrhythmia has also stopped! I still have my referral to a cardiologist, but my guess is, it will just be a "Yup, you're fine, go enjoy your life" visit.

Great job! Fantastic. Berberine can really work well with specific issues. Keep it up!

which berberine would you recommend and dosage?

@@Johnyy2009 I use the vitamin shoppe house brand. I take 2/3 dose or 1000 mg. My pcp helped me with the dosage for my situation. My cardiologist is happy with her recommendations. Your pcp would be able to direct you better.

Eat a handful of nuts daily (even peanuts) per the Harvard Nut Study.

How much do you take?

Mashallah May you continue to loose weight inshallah

Hi, yes it is probably stabilizing your blood sugar. When it comes to metabolism, sometime there are other issues involved like the thyroid. Watch this video: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-QN5WFN6Jh_E.html thanks for watching!

When you die where would you go Jesus Christ or satan Allah is moongod satan All Muslims going to hell fire sura 19.71 Jesus Christ is your answer

I fasted and noticed that my bp was better and sugar was much lower. I stopped meds for three weeks during ramadan just to test and i feel i can stop meds and fast to control both.

Hi, thanks for watching! Great comment. Also, watch out videos on Cholesterol: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-RBTrnIB2pK8.html and ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-RKnQ1zGFk6Q.html

What is your A1C? I have read that the dawn phenomenon has little effect on fasting BS.

@@Bass.Player it had went down from 13 to 6.4, when DP started it crept back up to around 10. I am now seeing a decline in my morning fasting numbers since starting berberine. I am still doing keto, 0 sugar, 0< carbs, 0 processed foods, high fat intake, high cruciferous veggie intake

Fantastic! Thank you for sharing this!

Mein Nüchternzucker steigt auch bei IF. Ich ernähre mich jetzt nach TCM esse jeden Morgen einen warmen Getreidebrei. Seitdem verliere ich Gewicht und mein BZ ist gefallen. Fasten verursacht bei mir Stress und erhöht den Blutzuckerspiegel. Ich esse jetzt 3 mal am Tag

Well done!!!

What dosage????

Excellent! Thanks for watching Peter!

Thanks so much! Very kind. Thanks for watching!

Thank you! I really appreciate you watching!

Great! Thanks for watching!

Should not exceed 1000 mg per day.

@The Goods Hello G , stick to 500 and you will be O K .

I'm thinking about getting my berberine from the roots of the Oregon grape plant. It's got a very large amount of berberine in them. It's a very common plant that grows wild all around many places. (Including where I live) All I need is a shovel and a short walk to the woods near me. Oregon grape is really easy to find. I wonder how the 🍵 tea will taste.

When do you take the Berberine? I take it at night a half an hour before my largest meal. I have not noticed any weight loss, but it has definitely made me constipated and I’m taking less than 500 mg..

@The Goods I'm not sure. My guess would be, probably some if the stems were harvested in the spring or summer, roots would be fall or winter. I have no idea what it would taste like or what other compounds in it might do. You should research that. Oregon grape is the plant with it, that grows around where I'm at.

Great on the progress and trying. Yes, I have had a few patients that high doses irritated the stomach. I have had some patients add in Essential Fatty acids (EFA's) and Cinnamon Verum, or Chromium Nicotinate Glycinate and push their results to even a better positive. I have also put patients on a ketogenic diet or us intermittent fasting and have seen amazing results. I have seen the ketogenic diet totally resolve insulin resistance completely to where the patient went completely off meds with no problem (you don't need insulin when your body gets into ketosis). Keep it up! I like what you have been doing so far.

What kind of Berberine do you take so many out there?

@@DrJasonPickel I have since gone up to 1000 mg a day berberine. My stomach adjusted to it.

@@tomlovin8931 Excellent! Thanks for update.

@@foxxymoxxy2433 You can go here: us.fullscript.com/welcome/drpickel and type Berberine Synergy in the Search. I like the Berberine Synergy by Designs for Health.

Fantastic Mary! Thanks for watching and sharing!

What dose and how long had you been taking it before you had labs done

@@gsp1634 I used 1200mg , 2 capsules a day and I took them a month before the test.

What a great comment - thank you so much!

Fantastic Frank! Thanks for watching!

Hi David! You are so right! Thanks for watching and the great comment!

Fantastic! Keep it up and thanks for watching!

Thank you for watching!

Great comment - here is study: pubmed.ncbi.nlm.nih.gov/35580317/ You are correct and thanks for watching!

Fantastic! Thanks for watching and the great comment!

Thank you!

Thanks for watching!

Excellent Don! That is exciting! Thanks for watching!

Great comment! I agree,, and this should be really done with any herb/botanical. Thanks for watching!

Thanks for watching Heather! Keep it up and thanks for sharing!

@@DrJasonPickel thanks for your great channel!!

Hi what brand are you taking? Thanks

Thanks for watching Andy!

Fantastic! Keep it up and thanks for watching!

I was told to take berberine a half an hour before meals, especially if your meal is going to be carb loaded. Dr. Andrew Huberman talks about this I’m confused because now I hear other people saying take it during a meal, mostly to avoid constipation.

Great Job! Thanks for watching!

Thanks for watching Jules!

Hi K, Many possibly factors: hypothyroid - make sure they test T3 and free T3 levels - ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-ls8Ij1d38Us.html , look into Carnitine: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-B7SgLupriTY.html , for physical activity try HIIT ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-w7JOoanNByc.html , and also watch this recent video on visceral fat loss: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-L20zwJK3b08.html Keep us posted!

Keto diet maybe!

May I ask what Brand to you buy there's so many out there?

@@foxxymoxxy2433 Hi, go here and sign up: us.fullscript.com/welcome/drpickel and then you will be allowed to order my favorite Berberine. In the search: Berberine Synergy and this is from a company called Designs for Heatlh. Hope that helps. Keep us posted and thanks for watching!

The Mediterranean keto diet was easy to follow and I could only stuff in enough food per day such that in 3 months I lost 30 pounds, reduced my Type 2 diabetic A1c and fasting blood sugar to normal, triglycerides went from over 500 to 138, LDL went from over 200 to 73, and HDL went from 26 to 41. Just remember, when a drug company does a study on their drugs, they get approval from the FDA by showing that their drug is better than a placebo while people continue to eat a typical crappy diet. No drug company would put their drug while eating a crap diet up against a calorically restricted Mediterranean keto diet alone because they KNOW FOR A FACT that they would lose. Not only is it easy to eat this way, it’s actually cheaper. NO ONE is making money off you being healthy. The bottom line is calories in calories out no matter what anyone says. Research suggests that those who are considered overweight or obese based on BMI are more successful in losing weight on calorically restricted low carb diets rather than diets that include an abundance of carbs because of the hormonal effects of carbohydrates on the feeling of satiation and feeding behavior. If you commit to do it, I am confident you will succeed!

Thanks for the tip! Great comment!

Great comment Ilana! Thanks for watching!

Great comment! Thanks for watching!

Thanks Barry! There is one study that shows this. Do watch this though: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-ZYjGaPd5onE.html Thanks for watching and the great comment!

Thanks for watching Regina!

I don’t believe your sister can take Berberine while she is on a blood thinner, I’m surprised dr Pickle didn’t tell you this !

@@anneluck2626 Thank you. I won't tell her about it.. she's very cautious. Her kidneys have been healing with a special low meat diet from a naturopath kidney doctor. God BLESS you.

Hi Tony, I really like Berberine Synergy from Designs for Health. Go here to order: fullscript.link/Products You will have to set up an account.

Hi Caridad, thanks for watching! Yes, go here: Go to the link: fullscript.link/Products and search Berberine

Thanks for watching Ben!

Hi Serfino, thanks for the great comment!

Hi Melissa, thanks for watching!

Glad you enjoyed it

Great question! Over many years I have tried soooo many product, but have to use things actually work and create changes on blood tests and get people better. Right now I like Optimal Health Systems (no synthetics - all supplements are made from whole foods): optimalhealthsystems.link/products and Fullscript carries many of the professional brands that most doctors use: fullscript.link/Products On Fullscript - look up Berberine Syngergy - this is the one I use the most. Thanks for watching!

LOL! Thanks for watching Jesse!

@@DrJasonPickel I appreciate your advice. I’ve been semi-crippled for decades.& I’m always on the hunt for any natural remedy ❤️

Hi Wilson, I don't know of any interactions, but it would be good to ask your pharmacist. Thanks for watching!! Also, for cerebellar atrophy we have had great results by eliminating gluten from the diet.

@@DrJasonPickel Thanks!! -I am in Keto diet, for both the Epilepsy and for the Cerebellar Atrophy. -I read that there is not a treatment for the Cerebellar Atrophy, that is why I thought Berberine could help. -Ok, I am going to ask the pharmacist !!!👍 -Thanks for all your videos, they are excellents, lots of information!!! (Sorry for my English, l am from Puerto Rico 🇵🇷)

That means ur taking a placebo which is not berberine coz 3,000 mg per day shud give u some side effects think twice !

I do have some patients with Lupus that it has helped. There are too many variable though. With autoimmune issues we must treat the patient and not their diagnosis. Thanks for watching!

Yes, every once in awhile someone does react to it. You may have to start with a half cap or less and work your way up. There are other alternative to Metformin besides berberine also - I use this one with patients many times: optimalhealthsystems.com/optimal-fat-sugar-trim#code=OHSPICKEL Great comment! Thanks!

Hi Charles how's it going, hope all is well. Had to throw my 2¢ in haha. Have you looked into your diet/lifestyle? Look up the Carnivore Diet and the people, Doctors, helping others. Best Wishes!

I wish insurance companies would start reimbursing you for some supplements but since BIG PHARMA controls everything that will never happen.

I have many of may patients take it before meals or with the first bite. Thanks for watching Lewis!

Hi Nick, great comment! See this video: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-RBTrnIB2pK8.html it shows how you are totally correct!

Absolutely! Great comment! Thanks for watching!

Thanks for watching Melinda!

Great! Thanks for the comment!

Is this through a prescription?

Thanks for watching!

Fantastic! Very exciting! Thanks for watching!

Dose please

Hi Deborah, I would need more information. Dosage varies per patient situation. The end of this video or another that I have done on Berberine may give you more insight. Thanks for watching!

Hi Ya Sim, I tend to have patient take it before meals or at beginning of meals. Thanks for watching!

Hi! Thanks for watching! There really isn't and it varies so much per person. With our patients we must individualize treatment and figure out which supplements work for them and rule out interactions. Great question though.

Hi Sue! That is fantastic! Thanks for sharing.

Hi Aaron, You can go here: us.fullscript.com/welcome/drp... and type Berberine in the Search. I like the Berberine Synergy by Designs for Health.

Thanks for watching Mike!

@@DrJasonPickel Thanks for sharing your knowledge

Thank you so much for watching Phyliss!

Hi, great questions! Like any herb, you have to take breaks about every 2 to 3 months because the body adapts, or increase dosage. Long term is no problem unlike longterm Metformin which has a long list of side effects. I have never seen research on niacin causing diabetes though. Also, because it deals with insulin resistance, aromatization decreases and testosterone increases in men. Thanks for watching and commenting!

Take with MCT oil to reduce those issues

Great! Thanks for watching!

Funny! Thanks for watching!

Great comment Tony! You are totally right, everybody's physiology is different and absorption may vary.

@@DrJasonPickel Thanks Doc, enjoy your channel, subbed and looking forward to watching more...

I've heard that Dihydroberberine is 5x more absorbent than regular Bergerine but it's more expensive.

Ha it made me constipated! When do you take your berberine? I was told to take it a half an hour before meals. But I ended up being late and being constipated. Maybe it’s not getting absorbed all the way because I have more sugar cravings in the usual I work out a lot but when I go to bed, I am off and get out and watermelon and papaya and grapes and almond chocolate on them. It just doesn’t stop 😭I just want to get eight hours of sleep without waking up wanting frui

Yes, the body does adapt to herbals/botanicals - can take 2 weeks to 2 months off - just depends upon your situation and need. Great question!

@@DrJasonPickel ok! Thank you!!

Hi Steven, great comment and thanks for watching! I was also surprised with the research and benefits.

Hi Steve, great comment! Yes, I wish more people/patients would be told of alternatives. Thanks for watching!

Vit k2 has been known to have a positive affect on calcium problems. Who would've known it could do so much good. Check out the book Vit K 2 and the Calcium paradox.

Great! Keep us posted! Thanks for watching.

How did it go?

Have you given up on this project?

Hi, I have seen this when the dose is too high. Thanks for watching!

Hi, great question! The research on this is great - especially compared to metformin. I rarely see any side effects, but some people, supplementing with berberine has been reported to cause gastrointestinal side effects, including diarrhea, constipation, flatulence, and stomach pain. Due to its ability to reduce blood sugar, berberine may increase the risk for hypoglycemia in high doses - blood sugars may drop too low. Usually all of this is a dosage issue, but could create the above symptoms if you have an autoimmune condition and can't tolerate Th1 stimulation. Hope that helps and thanks for watching!

Great comment Mark! Thanks for watching!

@@DrJasonPickel Thank you for your comment, The most common of these supplements are just scratching the surface. Many of the familiar ones many people know about are found to have new applications just being studied. These include supplements of vitamin D3. I had a D3 level of 7. My doctor diagnosed it many years ago and now I maintain a level of 81. Vitamin B1 in the form of Benfotiamine is very useful as is vitamin B6. My body did not tolerate berberine well. Two to three pills a day sent my ALT and AST very high. At least that;s what I think. Back to one pill a day brought it down to normal. It is still preferable to Metformin which is also a plant derived medication. I look at the ingredients in many of these expensive "cures" and research the chemistry and bioactivity of them to see which ones make the most sense. Because of their power I am extremely cautious since my doctor has never even heard of most of them although she did advise me to take melatonin. The real cutting edge is in epigenetics, the turning on and off genes through activation of sirtuins. These are scary and complex. Dr. David Sinclair of Harvard University is a pioneer in this field but it has gained a lot of interest. Even he has a lot to learn and sometimes gets it wrong. Another area is senolytics, killing senolytic cells or reverting them back to an earlier viable cell. Experts say that you do not want to destroy all of them. Resveratrol has contradictory effects at high dose and low dose. Sinclair takes 1 gram a day but it has the opposite effect of 100 mg a day. High dose resveratrol plus metformin is being experimented in cancer treatment. Of 7 sirtuin activators 1,3, and 6 are being studied. NMN is showing promising results but there are three factors that have to be dealt with to get it to work efficiently. There are other nutriceuticals that can generate NAD+ through other pathways. I'm fascinated by all of the research and results being done as this entirely new field is exploding with activity. There are also a lot of misleading claims for expensive products that offer hope to people with illnesses that don't work so you really have to be careful. Some are very expensive. So far the most expensive one I've seen is the only activator for sirt 6 that promises to reverse aging but others also have justifiable claims based on well documented double blind trials.

Hi, THanks for watching! Haven't see this occur before. Test creatine kinase on blood test for sarcopenia. Keep us posted. For the muscle wasting and prevention, I would use this: optimalhealthsystems.link/Muscle-RX

fullscript.link/Products create an account and search for Berberine Synergy (probably my favorite). Thanks for watching!

Hi Linda, Thanks for watching! They are definitely different. I think doing a video on Bergamot is a great idea and will add it to the list.

@@DrJasonPickel Thank you Dr Sorry i have just seen your reply My apologies I look forward to your review.

Hi, thanks for watching! Go to the link: fullscript.link/Products and search Berberine. I really like the Berberine Synergy by Designs for Health, but there are many other great ones here. As far as HCL, both of those are fine.

Hi, I tend to have patients take a break every 60 to 90 days at least. Great question and thanks for watching!

Great question! Thanks for watching J M!

Interesting! Thanks for watching and commenting!

Hi, Berberine decreases insulin resistance, so there is less need for insulin. It does not increase insulin. Coupling this with diet is the key. Thanks for watching!

Hi Jason, I have many patients that are body builders that use this and also L-carnitine (I like this one: optimalhealthsystems.link/Carnitine ) Thanks for watching!

@@DrJasonPickel i currently use L- Carnitine, I was asking about Berberine ?

Thanks for watching!

Thanks for watching! I decreases insulin resistance among other thing. Watch this video also: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-zkfNxKYf2T4.html

Hi John, thanks for watching! For patients who are reactive to this I will use this instead: optimalhealthsystems.link/Fat-Sugar-Trim

Take with MCT oil to reduce side effects and increase absorption. There are research papers about this