Berberine: Type 2 Diabetes Game Changer

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Berberine Helps Release Insulin From Pancreas
Berberine is a magical molecule with a vast array of effects. Today we will focus on the mechanism of insulin release and the impact of Berberine on the pancreatic beta cells.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
References:
Frontiers | Glucose-lowering effect of berberine on type 2 diabetes: A systematic review and meta-analysis
www.frontiersi...
ATP-sensitive K+ channels in pancreatic beta-cells. Spare-channel hypothesis - PubMed
pubmed.ncbi.nl...

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7 окт 2024

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Комментарии : 128

@jovoorheescollinsmphbsnbch6245 Год назад

Thank you so much for this lecture Dr. Been!! I am a diabetes management coach and i I have shared this video with my diabetes support groups totaling 90K viewers 😁 this is going to be so helpful for them!!!

@fijyify Год назад

I read this randomized controlled study "Effect of berberine administration on metabolic syndrome, insulin sensitivity, and insulin secretion" that showed that"Administration of berberine leads to remission of metabolic syndrome and decreases in waist circumference, SBP, triglycerides, and total insulin secretion, with an increase in insulin sensitivity". So, it appears that berberine doesn't increase insulin secretion. Another study showed that "Berberine induces GLP-1 secretion through activation of bitter taste receptor pathways".

@billytheweasel Год назад

Study titles much appreciated!

@HerbalAmandaL Год назад

@@billytheweasel I believe the title is the 1st part of the statement in Quotation 😀

@HerbalAmandaL Год назад

Your quote says "with an increase in insulin sensitivity" but then you state that it doesn't - I'm confused 🤔

@billytheweasel Год назад

@@HerbalAmandaL yep and I really appreciate that!

@BCSTS Год назад

@@HerbalAmandaL I think you should read his/her comment again....maybe find & peruse the study referred to....I do not see where there is a contradiction....

@t.hunter4660 Год назад

My mother has been taking Berberine for a few years to help with her cholesterol levels. I am really looking forward to hearing the rest of this series. Thank you so much Dr Been!!!

@terfalicious Год назад

How is it working for your mother?

@jovoorheescollinsmphbsnbch6245 Год назад

Have you noticed it has helped her?

@mygundidntdoit999 Год назад

You might have your mother's iron levels checked while she's on Berberine, because I read where it chelates the iron. I became anemic and figured out Berberine was contributing to it. Other things that I've found which work just as good are Bitter Melon and Amla.

@terfalicious Год назад

@@mygundidntdoit999 Thanks - I have ongoing problems with anemia, and this info is appreciated!

@nipagandhi7251 Год назад

You are such a Great Teacher 👍👍👍

@bobchannell3553 Год назад

Very good talk. I understand. Thanks for the video. Since I have type two diabetes, I'll try to watch all of the videos in this series.

@sherrystouth7707 Год назад

I tested as prediabetic twice in 2021 and my dr just dismissed that i had all the symptoms of insulin resistance, so i began taking bererine on my own (since i wasnt put on any pharmas to help) and its helped a lot.

@ssss-xt3dk 7 месяцев назад

Can you please tell what is your current situation

@melznutz3313 4 месяца назад

Cannot out exercise a bad diet. Stop eating bread and drinking sugar water now and ur halfway there! Take a lil time with the rest and make the changes permanent. Cheers 🌞

@MamaRestInPeace1424 Год назад

Dr Been you are a truly wonderful Researcher and Doctor. Your help to humanity is beyond words. Thank You!

@moneymattersforeverybody Год назад

I really appreciate your lectures. Have been praying about joining for some time and finally today, took the plunge. $67 for lifetime access is a no brainer! Thank you! ~Terri

@breathless8075 Год назад

I have just found your channel and I I have type 2 Diabetes. I am always interested in what I can do to continue working on my diagnosis. It's really changed my way of life and has made it not too fun. So much that we do traditionally involves food, when we gather with friends and family. I don't know much about Diabetes but I want to learn. Thanks so much for this lesson. Could be life changing.

@brenda126176 Год назад

I am so impressed with you!!! Joining your channel today, God willing!

@brenda126176 Год назад

Done deal😀

@DrBeenMedicalLectures Год назад

Thank you 🙏

@atrumluminarium Год назад

Would be nice to see a Metformin vs Berberine deep dive as a future lecture

@cindypendleton7901 Год назад

My husband is allergic to metformin. He does great in berberine.

@pamwaldron3504 4 месяца назад

Why don't pharmacists and doctors warn you that networking reduces one of the B vitamins over time to the point you will become so deficient you will die? I consider that to be negligence at best and attempted murder at worst. If you take Metformin, supplement your B vitamins from the beginning if you'd rather live and be healthy.

@margaretmacinnes1519 Год назад

Thank You Dr Mobeen and all The Koolbeens!!! Great lecture to begin the study of Berberine♥️♥️♥️ wishing all a good night 😴💤🌙 😄🙏

@DrBeenMedicalLectures Год назад

Thank you @Margaret!

@mygundidntdoit999 Год назад

Thanks for the great video. I have pre diabetes and have used Berberine, and it works. The only side effects I've seen are constipation and it lowers iron. I became anemic and figured out Berberine was contributing to it. I still take Berberine every once in a while, but use bitter melon, amla and other things most of the time.

@2bbossfree Год назад

I have not seen a lowering of my iron....I cook with an iron skillet. Think that has anything to do with it? I have pre diabetes, high cholesterol and macular degeneration, so happy with the supplement.

@9111logic Год назад

Sorry I could not follow you live from the UK - Marvellous explanation, perfectly understandable, thank you so very much again our dearest Mobeen 🙏🥰

@terfalicious Год назад

Love the obligatory cat tail passing by! 😻Love to Kyrie!

@amywjn Год назад

Thank you for going over the studies & being to thorough & unbiased.

@johnsnider2006 Год назад

If you mix it with Metformin there is a synergist effect, especially if mixed with tummeric and sage, and can lower blood sugar very low. It also becomes cardiotoxic if mixed with statins.

@DrBeenMedicalLectures Год назад

Thank you. I will discuss.

@annalisette5897 Год назад

This is a big surprise! Berberine occurs in Mahonia aquifolium, Oregon's state flower the Oregon grape. Native Americans used parts of the plant medicinally but those parts of the plants have been considered to be fairly toxic. The berries are edible but generally unpleasant. The roots bleed yellow when dug up. Roots, bark and berries can be used to make a variety of dyes ranging from yellow to purple.

@barbaraseville4139 11 месяцев назад

The ripe berries make very tasty jam.

@barbaraseville4139 5 месяцев назад

Ripe berries make a delicious jam. Recipes are on line.😊

@johnsnider2006 Год назад

As an antibiotic it is a mild antibiotic, but the value in it is it destroys the biofilm making other antibiotics more effective

@DrBeenMedicalLectures Год назад

Excellent

@janetmasleid4085 Год назад

John, is berberine ever used as a nasal rinse (topically)? for biofilm issues

@halifaxlithos2488 Год назад

I always learn from your presentations, Dr. Mobeen. As an added benefit, I find them enjoyable. I look forward to seeing more of you and your cat in the future.

@terfalicious Год назад

Very excited for the series. Especially interested on effects on the kidney, as I have had problems (genetic predisposition to PCKD). Also wondering about Vit D effects on kidney - I've read conflicting info. THANK YOU Dr Been!

@lisashapiro4714 Год назад

This is terrific

@AlimaElysee Год назад

A loved one was taken off his diabetic and hypertension meds after hospitalization last month for AKI subsequent to a bout with the virus. Thankfully, his readings have been excellent without them. Our physician recently approved adding berberine and quercetin/bromelain for nutritional support. It is reassuring to learn how effective berberine is especially with kidney function. Thank you, Dr. Been for your untiring, diligent research and dedication to disseminating this vital knowledge.

@kayemoore Год назад

Very clear, super helpful!

@MakaiMauka Год назад

My wife was taking 24 unit of insulin daily. Now takes 4 units of insulin daily after starting Berberine 500mg twice daily. Promises she did nothing else differently. Quite amazing.

@headybrew 4 месяца назад

How do the K+ ions get into the cell? Perhaps I missed that... Thanks for you great video explaining beta cell function.

@PeterQuentercrimsonbamboo Год назад

Well… we have been using plant medicines that contain berberine for decades in natural health practice for benefiting such conditions -

@jeffrey4577 Год назад

Outstanding

@glenndavis4452 Год назад

Have heard this from other medical discussions. They recommended it with circumin

@DaisyIdes Год назад

Thank you for this one. I just recently purchased Berberine for this purpose. My numbers are not terrible, but I am a smidge above normal. I also saw studies showing berberine may be effective in helping with dementia (diabetes 3). My mother died of Alzheimer’s, so this is also of import to me and my family.

@sheilahendrix5935 Год назад

May 💚God💛 Be ❤️With 💜Everyone💛 Always❤️ Much 💜Love Blessings 💛Always ☺️ ✌️✌️🎇🌈🌐💜❤️💛💛💚💙💙💚💚💛❤️💜💜

@aliyamea Год назад

Another good show!!

@seanvogel8067 Год назад

Thanks!

@DrBeenMedicalLectures Год назад

Thank you

@randyromines7364 Год назад

I have non-insulin required blood sugar to manage. My injectable has become unavailable due to supply issues etc. This sounds like the perfect thing to start taking to help control sugar levels. Funny thing is when I could no longer use the injectible I suddenly dropped 14 lb in less than 2 months and have not gained it back.

@delarrubio Год назад

The berberine effect that blocks the clearing of potassium, and as a result, calcium receptor channels opening up, does it mean you should avoid taking berberine if you are taking ACE inhibitors(ramipril) and calcium channel blockers like amlodipine? Or, does lowering the dose of ACE and/or CCB can work in tandem with BBRN? Thanks for your very detailed illustrations Dr.!

@billytheweasel Год назад

Great reminder. I ran out of berberine before we moved from America.

@2bbossfree Год назад

Earl gray tea has berberine and Stack makes a high berberine teabag. It is in a citrus fruit used in Italy and some think this might be part of the reason why the Mediterranean diet was thought to be so good, along with olive oil instead of canola oil. Without the berberine, the Mediterranean diet is very different.

@n.a.1397 2 месяца назад

Ordinary Early Grey tea is just bergamout added to black tea, no? It doesn't have berberine? Wht is STack?

@sheilahendrix5935 Год назад

Peace💛 and 💚Blessings❤️ Too 💙My💜 Brother 💚May❤️ God💙 Bless 💛You 💚Always ❤️May 💙God💛 Bless 💚You ❤️Richly💙 with Everything💚 You ❤️need💙 Always Much💛 Love 💚Blessings💙 Always ☺️ 🎇🌈🌐✌️💯💛💚❤️❤️❤️❤️💚💚❤️❤️❤️❤️

@FightBackAgainstDiabetes 9 месяцев назад

*You Did Not Choose To Be Classified As Diabetic, But You Can Choose To Fight Back Against Diabetes* 💪

@HerbalAmandaL Год назад

It is my opinion that it much better to use the plants rather than the supplement. This is why turmeric is one of my favorite herbs for my diabetic clients with fenugreek ❤️

@HerbalAmandaL Год назад

Same for cardiovascular and even autoimmune

@jayajora Год назад

Huh? Not in India

@HerbalAmandaL Год назад

@@jayajora what do you mean, "not in India."??

@jayajora Год назад

@@HerbalAmandaL turmeric is part if their everyday use yet diabetes out of control

@HerbalAmandaL Год назад

@@jayajora oh, I see now what you meant. Eating it as a spice and using it medicinally are 2 different things. You can also use other herbs, berberine is the chemical found in them. Using the whole plant as medicine provides better synergy than just 1 chemical. 😀

@tinyspeckofdust37 9 месяцев назад

This explanation is fantastic ! Dr Been would you be kind enough to do the same with thyroid hormones and all the connections including Reverse T3 and perhaps highlight the most important natural treatment eg. A supplement or a beneficial herb please? And if you could discuss Adrenal exhaustion and what can be helpful based on your research? That would be very much appreciated 💕 thank you. Ps. I have been taking Berberine for around 2 months.

@vickiredfeather4808 Год назад

Been using for years. Would like to know best brand

@mrsrichter8586 Год назад

I am even more confused now - there is berberine from the berries, called barberry. And there's berberine from the bark of the plant and berberine from the roots of the plant all sold seperately as berberine. Whyyyy??? What's the difference and why must everything be so complicated and confusing?

@lindapestridge3073 Год назад

Dr would you do a video On bergamot please.

@bilel1299 Год назад

I used to be type 1 here, but I'm now out of control owing to a terrible diet. Carbohydrate diets are easier to follow. I was forced to use the gluconize brand. check if it works

@sandrajones2926 Год назад

nice art

@pettutor4213 Год назад

Does increasing insulin with this mechanism also risk increasing insulin resistance? I would think we want to increase insulin sensivity and not increase total insulin. Great lecture I joined your lifetime membership program.

@HousesForSaleCairns Год назад

It decreases insulin resistance!

@bobthrasher8226 Год назад

I hope Dr Been will look into high-dose Thiamine - see the book "Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition" - may provide help to long haulers and many other conditions.

@christineknapp-phillips Год назад

Yes! Dr. Lonsdale book is amazing! Research and presentations by Lonsdale, Constantino, Marrs, Overton has been so helpful.

@bobthrasher8226 Год назад

@@christineknapp-phillips Glad you found them. I know Dr Been has covered thiamine but I don't think he or Dr Marik appreciate high-dose vitamin therapy yet.

@jeffreyscottfishman Год назад

Im worried about Berberine lowering blood pressure. What if you already have low blood pressure? Will it make it worse?

@DrBeenMedicalLectures Год назад

I will discuss in a future talk.

@jeffreyscottfishman Год назад

@@DrBeenMedicalLectures Great, thanks!

@diana12701 Год назад

I have a question I started taking barberine and I get really bad bloated want to not give up 😕on the barberine. any advise in how I can prevent the bloated from happening 🙏thank you Dr.Mobeen p.s love your drawings 👍

@leifkring6346 Год назад

I've been searching for natural compounds which can reduce glutamine. So far I've only found two, of which berberine is one. Cancer cells use glucose as fuel, so by a ketogenic diet you can minimize the glucose levels and this can be enough to kill some cancers. But if the cancer cells don't have access to glucose, they will use glutamine as fuel. There are some glutamine-blocking drugs, e.g. 6-diazo-5-oxo-norleucine (DON), but they are not available. They also have some bad side effects. Theanine is the other natural compund that can have a glutamine-reducing effect, as it inhibits the glutamine transporter. Can anyone suggest some other glutamine-inhibiting natural compounds?

@upriver7047 Год назад

Thank You! Your explanation was very helpful. Do you think Berberine with the addition of cinnamon or milk thistle would be helpful to better absorption of the berberine? Or is it better to just increase the dosage of berberine? I'm subscribing to learn more from you. I appreciate your efforts to educate the general population.

@dwdwone Год назад

This sounds very similar to how sulfonylurea drugs like glypizides work in the pancreas in that the calcium channels are manipulated by a change in polarity. Is it the same kind of mechanism but in the liver?

@patriciamuscat1049 11 месяцев назад

Thank you for your lectures Im a patient with heart failure and Im on medication Entresto, Jardiance, spironolactone, nebivolol, and rivaxoban. can we take it ?

@mehtabbandesha5637 Год назад

awesome

@dwightcarlson7136 Год назад

Would like to hear whether taking Berberine with Metformin is good, bad or indifferent????

@denachubbic9494 Год назад

Thanks to your teaching I understand what berberine does. But how does berberine do it? How does it close the less active potassium channel?

@dwdwone Год назад

I'm not sure but I think it changes the polarity due to its natural structure.

@DrBeenMedicalLectures Год назад

It binds to these channels.

@marantz747 4 месяца назад

How long is berberine effective in a diabetic? Does it become less effective after 5 or 10 years?

@rimavanhill-seal7557 Год назад

I missed it

@DrBeenMedicalLectures Год назад

No worries.

@janetmasleid4085 Год назад

@@DrBeenMedicalLectures Great subject matter! So glad you're doing a series on Berberine!!! : ))

@katl6320 5 месяцев назад

are there any side effects of berberine? i am hypoglycemic (self diagnosed)

@FahlstromJohn 10 месяцев назад

will Berberine cause elevated fasting insulin?

@johnreas9216 Год назад

Illustrated to perfection!!….I’m hereby dubbing Dr.Been not only as his rightfully deserved KingBeen, but also as: ‘Picasso-Been’.🧐

@Aviation_Professional Год назад

Do we have a good comparison vs Metformin ??

@HappyLife-wv5ms Год назад

Is there an increase in intestinal infections with long term use of berberine?

@zbyszek2951 Год назад

Other medicines increasing production of insulin can cause hypoglycemia due to continue of work at low level of glucose. What is difference? does it means that they are closing one or both channels more tightly or open Ca++ to let insulin out?

@dorotap9423 Год назад

Can berberine be used long term?

@JJ-hg5ho Год назад

🙏

@dwightcarlson7136 Год назад

I believe bananas have quite a bit of potassium. Therefore is it good to eat bananas to reduce A1C?

@FahlstromJohn 10 месяцев назад

many report very high glucose numbers after eating banana...might be better to get potassium from other sources

@babayaga5225 Год назад

I got to be honest. I felt really uncomfortable when at the 6 minute mark you mentioned, "it has the potential to treat some cancers". There should be a BIG disclaimer there.

@scotmil1 Год назад

So you are cool talking about diabetes, but mentioning a potential in treating some cancers is taboo? He wrote "Anti tumor effect." I am sure you are going to make it through this emotional setback.

@KathyCreed-dj3fn Год назад

Thanks!

@babayaga5225 Год назад

I got to be honest. I felt really uncomfortable when at the 6 minute mark you mentioned, "it has the potential to treat some cancers". There should be a BIG disclaimer there.

@terfalicious Год назад

"Potential to" IS a disclaimer - same as saying "MAY/MIGHT" do something, not that it absolutely "DOES" do something. Even in studies that show efficacy and/or causality, individual results MAY vary.

@setapart27 Год назад

@@terfalicious I hope you investigate the poisonous poke also..😢

@terfalicious Год назад

@@setapart27 I stay far, far away from crazy-eyed people with coming at me with needles - especially those sent by the gov't or captured corporations; I read my George Orwell back in the day!