David Sinclair Responds To The NMN Supplement Ban! 

• David's letter: twitter.com/agingdoc1/status/1603542845092429826 • Join Patreon For Access to Early Videos, The 5-Years Younger Online Course, & Discord Chat: www.patreon.com/bradstanfieldmd • www.donotage.org/products | Use code BRAD for 10% off

Kudos for calling out what Dr. Sinclair has done and is doing.

In Sinclair’s book, Lifespan, he details his incredible research into NMN and then spouts the anecdotal miracle his elderly father experienced from taking buckets of NMN. But now he’s behind preventing my elderly mother from getting it over the counter. Pure greed. Thanks for your good work and bravery on publishing the truth on both the research and supplement space. P.S. We both indulge in niacin based on your information on its effectiveness as a precursor for increasing NMN as a naturally occurring molecule. And shame on the FDA for granting an individual biotech company proprietary rights…to a naturally occurring molecule. Schmucks.

Congratulations on the birth of your baby. I’m sure there is a lot more on your mind right now than David Sinclair. Thank you for taking the time to promptly respond to his letter. It’s much appreciated.

“Great diet, regular exercise, high quality sleep, making sure that you’ve got life purpose and that you’re socializing” dude you nailed it!

Mad respect for you keeping things real

Well done! Holding Sinclair accountable for his lies driven by greed is why I continue to value your channel. Congrats on your newborn. More of you on this earth is a blessing.

Thank you for calling out his BS! I don’t get why he has to be so greedy if he’s already made hundreds of millions of dollars. Also congratulations on the new baby. 🙌🏻

The FDA also is not supposed to patent naturally occurring molecules or ban naturally occurring molecules in the food supply already, so it has violated its own rules twice over.

Thank you for calling this out! It’s so easy to blindly trust someone like Sinclair if it were not for someone like you. Congrats on your new baby and thank you for sharing this incredible content! ❤

I’m so sick of the corruption going on with the supplement industry. NMN helps people! David A. Sinclair is truly a monster and should be brought the justifying punishments for his greedy actions…

Thank you for your work. Yes, David has become unethical, it appears. He needs to be asked these questions that you have presented to us. I hope someone in the podcast community feels the same way and can have him explain this, if he will.

Congratulations on your baby!! And thank you so much for the work you do, your videos are awesome!

Thank you for a clear and concise summary on the current state-of-play with NMN. Seriously, David Sinclair appears to have lost all respect from his many admiring and faithful followers. And for what? It appears to be... the power of the almighty $$$$$.

He is trying to distance himself because there is no advantage in not doing so. In that way, he would not lose his admirers who might be handy in some way regarding other projects.

Brad back in the mid 2000s I was researching this field and Sinclair became a media darling until he misled GSK and this guy was written off by researchers! He has a revival now with a new wave 🌊 of people into this field now that know little of his past history. Keep it up! 👍

No matter how much I like his work, a story about longevity, I always had a bad gut feeling about him. Seems my intuition was correct.

Dr. Stanfield, you are the MVP to flash out light that Sinclair has been fooling people for years. All thanks to you, you rocked the NMN world from East to the West !!! Best wishes from India 🇮🇳

Thanks Dr. Brad, I've watched all Sinclair's hours and hours of podcasts on Lifespan. He was my hero. I put him high up there and this video crushed me and brought Sinclair back down to our mortal status.

Congratulations on the birth of your baby, Dr. Stanfield. - It has a Dad you calls out things as they are and is not afraid at all of big names. What a gift❣ 🥰

Sinclair at his best. I stopped trusting him long ago. He is 90% sales man and 10% scientist. I could on and on but in the end all he does and says is purely targeted at generating profit. If he contributes something to the scientific field that is actually of benefit, its just a side effect. It is mindblowing to me that he did this before with resveratrol. Still, he will wiggle his way out of this just like all the other con artists and continue to build up his brand. Congrats on your newborn!

Why didn't he mention NR (Nicotinamide riboside) as a precursor specifically. It is not subject to an over-the-counter possible ban.

Thank you!!! I have high respect and appreciation for your approach to sharing and disseminating research data on aging supplements and lifestyle actions for healthy aging.

The guilty party here is the FDA, blaming the companies is a red herring.

Sinclair has shown his true colours. He is driven by money.

I always had a sketchy feeling about David Sinclair. Thank you for exposing this😊

Mad respect for your direct style and that you show your sources. 'Trust but Verify' words that I am glad to see embodied in your channel. Cheers!

Thank you for what you do for all of us. You are the voice of reason and truth in an industry you've decoded for all of us with your knowledge, in a time when deception is at an all time high !

Thanks for putting this out there while sleep deprived!

As stated before: Never trust anyone that went to Harvard. Your advise and analysis are spot on. Exercise alone will double your NAD levels. Good work. 👍

What an unscrupulous low level human. Thank you for sharing. I for one will never support anything he does. As a matter a fact I'm going to share this video and let everyone become more aware .

This is massively appreciated. My year supply of NMN will hopefully help tide me over through any difficulty if I need to secure it internationally in the future.

As a physician taking NMN, rapamycin etc, I am very disappointed with Dr. Sinclair's company and his response to the actions of Metro I. Biotech. Sadly, another example of the unethical conduct of pharma in general. While pharma brings us many new and life saving medications, I believe their mantra is "profit above all else".

Thank you for taking the time to respond to his letter. It seemed strange to me that he is distancing himself from his company. Makes me think that a deal is imminent- history repeating itself as you have aptly put it. Huge congrats on your baby 🎉

Brad, your videos deserve to get 1000 times more views than all the BS David Sinclair pushes out.

The "important work" of bringing NMN to market as an FDA-approved medication is NOT in the best interest of anyone but David Sinclear/Metro-Biotech. Congrats on your new baby and good luck with the rapamycin study.

Holy FUCK. This is STUNNING to me - I’ve been inspired by David’s message recently - is he just a complete scammer, or is there some kind of gray area here? Very interesting

SO useful thank you so much for this clarity and investigative journalism. If only everyone had as much integrity as you and care for the consumer and democratic access to health improvement apart from grotesque commercial cynicism and ruthlessness.

Congratulations on your little doctor. Your advice and information alwys clear and clean. Thanks for your hard work. Can you please talk about peptide which is BPC157 or thymosin alpha 1. This gonna helps a lot. Again wish your good health and success in your research.

Thanks for reporting on this, Dr. Stanfield. Sinclair has had that smell clinging to him for a while, but it's pretty clear now what he's all about.

Love the Chanel congratulations on the new arrival!

Wow! I just found your channel and discovered Dr Sinclair earlier this year. I was sharing his advice/research with anyone who would listen and was about to buy his book and more. RU-vid recommended you and what a wonderful surprise! Thank you!

Still the most objective professional in the anti-ageing community. Thank you Dr. Stanfield

Congrats Dr Brad! Happy for you and your wife!

I agree with you Dr. Brad. Keep doing what you do. Congrats on the new addition to your family.

Thank you for bringing this to light!

Not sure what everyone is using in terms of a brand, and I thought I share my experiences with NMN supplements. I have been using NMN for about 11 months, I am a 68-year-old male and I have tried over 20 different brands. The only one that seems to work for me personally is Probase Nutrition NMN Powder, simply because they are a well-known California brand, and I had their NMN independently tested for purity and impurities. Theirs came in at 99.89% purity and had zero lead in it. It seems some people on here have used Probase (the brand) NMN as well and they seem to be happy as well. Hope this helps!

Shysters gonna shyster. What a devious letter. Thanks for holding the Sam Bankman-Fried of anti-aging supplements to account. o/

Thank you for covering this so well.

a huge thank you for all your hard work and congrats on your new baby!

For a split second I thought the title meant Sinclair responded to your channel about the resveratrol controversy 😅

Thanks for keeping things science based and critical!

Congratulations on your new baby! And thanks for this update.

Oh! Congratulations on your newest addition to your family! As a mother of two boys, I remember the lack of sleep period very well. Mine are adults now. Enjoy every minute because before you know it your little ones will be grown. 💕

Thank you for exposing his shady actions here. I appreciate you and the information you always provide us 🙏

Looks like they want control to sell it as a prescription

My Respect for you Sir 📈 Thank you for keeping it real and continuing to remind people that diet, exercise, sleep and social well-being is the foundation of human health and longevity. You earned a new loyal subscriber sir.

Just subscribed to you, fullyyyy agree with your advice on the sleep, excercise, purpose and social life. No matter how many sups you take, that's really key.

Thanks for calling him out !

Thank you for your so important and unbiassed work, Dr Brad, and huge congrats for your second new born child !!!

Congratulations on welcoming your new family member! Thank you very much for this video! Seamlesly presented, concise, highly accurate. Most notable is that commanding, resonant voice! 👍👍👍 So perfect to draw listeners in and to keep their attention! What came to mind, when you said you didn't understand why DSl wants to distance himself from the issue (all the while instigating the subsequent complications of it)) is that scenario where, as soon as the child starts acting-up and misbehaving, the parent starts looking around (sheepishly), stepping back and feigning no relation to said child... Just until the child settles down, again. Also, DS is possibly proactively trying to avoid any potential backlash from irate consumers, who might associate the outcome of the situation with his tole in it. And said consumers might seek to retaliate against him, personally, instead of venting at the actual company. Protecting his own interests, as is the usual for the materialistic -minded. Yah, some people wants to "help us" ONLY inasmuch as it would benefit THEMSELVES!!👎 What could be clearer??

Great explainer. Thanks for your always very clear content. Any thoughts on the efficacy of NADH sub-lingual lozenges ? Best Regards from Singapore.

He is a better businessman than a researcher...

Thank you for putting Sinclair on blast. David Sinclair seems very shady because of this ordeal. People like me try to put some trust into the experts hoping they will optimize their life. I would be much more skeptical than normal with anything David Sinclair says from now on out. Peter Attia himself says the NMN supplements have poor evidence backing the amazing claims that are made.

Great video response to his Metro-penned letter.... Congrats on baby #2 Brad. They just become more and more amazing over the years.

It's all about the MONEY! This is crazy.

Thank you for this, Dr. Stanfield. I have been warning people about this for a long time and I've received much pushback and even hateful replies. It's been obvious to me for a long time that he is not honest or forthcoming. Even the way he appears physically does not look genuine to my eyes. Furthermore, many of his research "findings" cannot be replicated. Maybe it's just that I live in the U.S. and have become very sensitive about being gaslighted, but I know this guy is crooked.

Congratulations on your beautiful family and thank you for all your work!

Why would anyone take NMN knowing the character of the person behind it? Sinclair has said two things - that he knew he needed to make his mark in the world by providing an alternative to the free radical theory of aging AND that he himself takes lipoic acid because he believes Denham Harman, the man who discovered that theory.

Thanks for your work

Thank you for tracking this situation! I am trying to look at that from different point though. Who is going to spend money on further clinical trials if there is no way to even return invested money. Say, you are a company and want to invest in nmn studies, how will you make profit from that after the studies are done and showed great results? These studies I suppose are not cheap and you need to add this cost to product you sell. Also, you need to keep in mind that it's a risk and no one knows the results of those studies, they can fail. Who is going to buy your NMN (that includes costs of studies) if there are plenty of cheaper options of the same product from companies who didn't conduct the studies and don't need to cover those spendings? I totally agree that it's a shady move to remove nmn from the market, but thinking out of the box, how do you think should it work? You tried to collect 30k for rapamicin studies, and I don't know how it went, but I don't think there were tons of people donating for that. Investors give money because they want return on their investments. You have savings, right? And you don't donate all your savings, but you put it on your account or use other financial instruments to get profit on them or at least outperform inflation, right? Sorry if it sounds aggressive or offensive, english is not my primary language, I am just trying to bring up another point of view. It also amazes me how people hate big corporations because all they care is profit, but when those same people have some money to save/invest they choose to invest in exact those big corporations because they provide good ROI for their investments. Honestly, maybe it would be better if one company could sell nmn, they woud've got lots of money as investments and made lots of good clinical trials, and we'd know earlier if it works or not.

Sirtris didn't have a "proprietary blend of resveratrol". They had a completely different molecule that ostensibly affected sirtuin enzymes in the same way as resveratrol. It had zero effect on the use of resveratrol as a supplement.

Thanks Brad, its refreshing to hear honest takes instead of the "hype" that so many others are bringing without the integrity that they so definitely need.

Sinclair's continual promotion of resveratrol and refusal to debate others on the supplement destroyed any credibility he had left. This NMN situation only affirms that!!!

Thanks for this info. You are always on point. Excellent work.

Thanks for keeping us updated Brad! Been a long time listener to your Channel, i like David Sinclair but i am Suspicious of him and hope he doesn't go against the Longevity Community and what he stood for!

You can blame Sinclair but really it is the FDA that is at vault with its silly rules which make this happen. Sinclair just uses those rules but if he hadn't some other company would have. Congratulations BTW with the birth of your daughter 🎊🎉

It's so frustrating to see this happen over and over again to supplements that could help many more people if there wasn't a wall put up to make these supplements more exclusive and costly

Excellent informative video, one of your best!

hahaha I was wondering about your read eyes while watching your video and thanks for letting us know why 🙂 Congrats and a warm welcome to the new member of the Family Stanfield !! well done !!! I wish you lots of sleep, which is one of the most important anti-aging supporter ;-)

Congratulations on your new addition!

Of course you understand why he is distancing himself from his company, he does NOT want folks to hate him as a result of the NMN Ban.... lets NOT cloud the FACTS

Congratulations with your baby Brad! Happy for you and your family😀

Can't say this is surprising, should be criminal, instead greed seems to be the guiding force for those at the top these days, no pill for this ill. Thanks for keeping us informed.

Thank you for this video, explaining what's going on. I just want to say NMN has transformed my sleep which has transformed my life. So I don't think it's as simple as don't worry about supplements and just get good sleep, eat well, etc. Supplements like this one can help our bodies to overcome challenges that are not allowing our bodies to heal and be healthy.

Ever the clever, Dr. Sinclair doesn't mention that NR (Nicotinamide Riboside) supplementation results in NMN production within cells (let alone that it is more effective by weight than NMN), or that NR is not banned over-the-counter, and will not be. He knows that the NMN ban will go fully into effect. but would rather have people not get the benefits of either rather than direct buyers to the company associated with Dr. Brenner.

This actually goes against the FDA's previous rulings that you can't patent a naturally occurring chemical that's already made in the body.

Advancing his WEALTH is clearly his highest priority..

Great content and congratulations to you and your wife. Enjoy every second it goes fast.

Sinclair: "A company I cofounded but do not manage or control..." Stanfield: "So I don't understand why he is trying to distance himself from his own company!" Logic: Because he doesn't manage or control "his own" company?

Congratulations, on the new whānau member. It is a shame these already well off people get greedy.

Congratulations to the birth of your child, best (and long) future for you and your family and as always: Thank you for this update

Really interesting to hear about this development, I haven't ever taken NMN, but have been quite interested in the space of aging research since being introduced to the topic by various podcasts hosting Dr. Sinclair, so its good to get some follow up on the market side of his activity here! I wanted to mention that I have come across at least 3 of your videos before this and am hit with the same first thought every time about the audio quality, which is that its harsh to listen to the videos as there are some frequencies which are just out of balance for my ear. Maybe you could try processing your audio a bit differently in the future for easier listening, as I know I have actually stopped watching a video of yours previously due to this reason.

Ahhhh greed strikes again!

He gives NAC as a comparison. What a joke. His company will claim a patented formulation of NMN. The FDA will ban it OTC. The distant David Sinclair will claim it is beyond his control. So sick of this guy.

Thanks again. Very diplomatic Brad!

Thanks for the clarification

Congratulation! :)))

I don't know how Sinclair thought that his company doing this wouldn't completely destroy his reputation. If his company is doing without his authorization, as he wants to imply, then he should be the first one jumping over heads of people to kick the ass of whoever thought that it was a good idea, because by the end of this there will be nothing left of his reputation. He'll be known as slimy Dave for the rest of his life and every word coming out of his mouth will be followed by echoes of doubt and disgust.

Everyday my respect for you grows bigger. Dr. Brad. And at first i was a fan of Dr. David.