DNA Replication: Copying the Molecule of Life

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Your DNA needs to be in every cell in your body, so what happens when cells divide? How does each new cell retain all of the genetic information? The DNA is able to copy itself through a process called replication. Let's go through the finer points, shall we?
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Опубликовано:

7 сен 2016

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Комментарии : 444

@UnironicWizard 4 года назад

Gotta love how with quarantined schooling teachers have given up on teaching and recognized that people like you have been the ones actually teaching us.

@Emily-gy8pe 4 года назад

that why im currently watching this

@danjbro 2 года назад

@@Emily-gy8pe same!

@danjbro 2 года назад

🙌🏽

@jenniferstormlambert162 2 года назад

Professors and teachers are getting lazy and it is so much easier for them to just send us to a website and let someone else explain it! Thank you!

@KB-vd8wq 5 лет назад

You literally just summarized about half of what I learned in an entire semester-long molecular biology class in a 6 minute video. Nice.

@satinderjit4 2 года назад

Dang what!?!?!?!

@Malik-em6ng 2 года назад

really this is day one for us..... it is fricking hard XD

@harrietharlow9929 2 года назад

I love that I can learn by watching videos. I am interested in many subjects and my idea of a good session is learning something new. I will definitely be checking out Professor Dave!

@esahoosa 2 года назад

Even with a biology degree and in medical school, this is the most straight forward and easy to understand video on DNA replication. You sir are the GOAT.

@Sara-by7cf 3 года назад

You single handedly made me not only pass but EXCEL in my biology 101 class. Thank you professor dave

@nyxieempire8446 2 года назад

Every time I struggle to understand a course material and find out you have a video for it, I cry tears of joy

@susymadrid5903 Год назад

I have a biochem exam tomorrow and I could not keep the enzymes and their functions straight. Now I think I’ve got the hang of it! Thanks, Professor Dave

@jakarigainer5165 2 года назад

I just realized something very important in terms of how to interpret your animation. The directionality of the synthesis of the new strand is correct. However, I initially thought that the numbers you put on the leading strand was identifying the ends of the new strand, not the original strand. In other words, the new strand would read/synthesize as such: 3' under the 5' of the leading strand and 5' under the 3' of the leading strand with the arrow going in the same direction.

@grantcallen9763 7 месяцев назад

Doesn't polymerase travel 5' to 3' not 3' to 5'?

@HairyGarry 27 дней назад

Polymerase starts traveling at the 3’ end of the existing strand(so 3’to5’). The new strand it adds would be in the opposite direction. And that is what is confusing you.

@Akuty1 3 года назад

Thank you Prof. Dave! I spent like two hours trying to understand my professors lecture, and you helped quite a lot! I am really grateful that I found this video online. Thank you for what you do! :)

@adamgurman8756 7 лет назад

A great, fast, easy and organized video! Thanks!

@myvideosfortheworld6122 6 лет назад

sir you are a really talented teacher and a speaker ...... a process which would take me hrs to understand was made easy by you and i got it in juat 6 mins ! thanks man

@shanayalnaveed9100 6 лет назад

That Addicted Guy you forgot the 15 seconds

@kellyedsall9715 6 лет назад

This helped me so so much! Your video really cleared this up! Thank you!

@yashgokhale1460 7 лет назад

Super helpful! Would have taken hours for me to understand just by reading this. Thank you Sir!

@mushfiqurrahmanshishir8055 3 года назад

Thanks for this explanation. Some things are simplified. But this is a very good overview. It was really helpful.

@harrietharlow9929 2 года назад

I enjoy that I can learn the basics from your mini-lectures. Great job, Professor Dave. You put me in mind of my late father, a physician, teaching me about reproduction, mitosis, meiosis, etc. He started with onions and went on from there, ending with human reproduction when he felt it was age-appropriate (about 13-14 in my case). This puts me in mind of his teaching methods. I just subscribed a couple of hours ago and will be adding your videos to my Geology/Volcanology and Evolution and Extinctions playlists. So glad I found your channel!

@ambiavanessaanti4911 2 года назад

Thank you so much Prof Dave I wish you could explain the rolling cycle mechanism too

@oct_rz4736 6 лет назад

You are awesome.. I was jumping from video to another and I can’t understand that. But with you just in 6 min I take it very well !!

@sierraschopp4662 6 лет назад

This is such a great video! short and sweet :)

@Carter-wj9wn 7 лет назад

Your videos are so helpful!

@Bawan2610 7 лет назад

DNA chain can only be synthesized in 5'-to-3' direction, not 3 to 5. As the subunits is being added at the 3' end, that means it runs in 5'-to-3' direction....

@jdmg7284 7 лет назад

Bawan Colnadar I noticed that error in the vid as well

@rototon1992 7 лет назад

He's going to get people confused. Need an upgrade.

@pa800korg92 7 лет назад

Actually he's correct, the DNA polymerase III moves in a direction of 3'- 5' of the preexisting strand. However, the new strand that's being synthesized is 5'-'3. The video is crystal clear .

@hasnainabdurrehman2426 7 лет назад

The video is correct, but NOT clear. This "Dave" person knows the stuff but doesn't know how to explain it to a naive mind. Someone listening to this for the first time can get confused for all his life ! REPLICATION HAPPENS FROM 5 to 3 END !

@pa800korg92 7 лет назад

Sounds like you're not interested in using your logic only in memorizing facts.

@zaraanwari126 5 лет назад

Video was crystal clear . I understood the whole topic In ONLY 6 minutes where I didn’t get one thing through my head in a 80 minute class . Thank you so much Professor Dave !!

@chloeli4405 7 лет назад

5' and 3' DNA template strand should be more specific indicated in the slide. Its a little bit confusing.

@ProfessorDaveExplains 7 лет назад

yeah a lot of people have mentioned this, i wish i had made it a bit more clear. nothing i can do now!

@dawncorbin6140 6 лет назад

Yes, he needs to label the new and old strand as it is very confusing (he's labeling the old strand)......this is where students get mixed up often.

@MuhammadAwais-qc6bh 3 года назад

@@ProfessorDaveExplains You should make another video... Please sir this is a humble request...

@jamesbort8242 3 года назад

All the videos I have viewed on DNA replication struggle to explain the 5'-3' process. Unfortunately, this wasn't any better, but the rest of the video was helpful.

@jenm1 3 года назад

@@ProfessorDaveExplains annotations?

@moffeevalverde1403 3 года назад

I love the way you explain each step of DNA replication and other biological processes in your videos, I'm just glad to find your channel :')

@mayamade9047 7 лет назад

This is one of the best videos I have seen on DNA Replication!! thanks a whole whole lot!!

@cristinajones7211 3 года назад

Thank you for this.. I had no idea what was going on until I saw your videos! Thank you so so much!

@ewittka100 7 лет назад

Great explanation, thanks!

@vaibhavbaadkar1450 2 года назад

Explained in very easy and simple manner... Thank u sir

@atiyadavids4651 3 года назад

Best explanation I've ever heard and seen my whole life. Ily.

@lukamtc9188 Год назад

Loving the vids, I'm revising what I learned in the balkan equivalent of advanced biology & chemistry highschool. Just one thing: the audio volume is a bit low everywhere except the intro. These are old af but if you plan to make more videos maybe amplify the volume a bit in post.

@sarameame7864 4 года назад

Its perfect!!!!😍 Each time i want to search for something scientific i find a video for you, your explanation is perfecttttt, keep on Dr.♥️

@dhritimadas6357 3 года назад

Easy & concept clear explanation.... thank you sir.

@josephinekyalo610 Год назад

Your explanation is very clear and the footnotes are very helpful, i now can understand the replication process thankyou prof

@intellect_junction69 4 месяца назад

Bro, why does the microscopic world low key feels like a mini-society

@arhamcollectionofficial 2 года назад

Thank you sir I spend 2 days on this topic but this 6 minutes video clear my concepts too much

@ians4987 9 месяцев назад

hi professor. i thought polymerase creates the leading strand in a 5'-3' direction towards the fork?

@missjesseduph 3 года назад

I have a final task in Genetics, thanks for this vid. It means a lot to me!

@vlihumbtov4236 Год назад

Do you have a video about endogenous retroviruses (ERVs)? Would like to get a better grasp about the subject. Thanks for these videos btw. Really helpful.

@Youknowwho910 10 месяцев назад

Watched so many videos on this and this one finally made sense. Thank you!

@bobl9555 7 лет назад

Excellent video, Thanks!

@frapechinokelsey6451 3 года назад

I'm in 12 standard from INDIA 🇮🇳 & I found this video which really boosted my knowledge ☺

@aleynacabuk7352 2 года назад

Spending hours in boring college lectures with professors that lack the ability to teach and not learning ANYTHİNG vs watching a 6 minute video from a great teacher and understanding everything. I think I have spoken enough

@joshuahalsey1020 2 года назад

Makes so much more sense hearing it from you vs. in class

@janepiccirilli4654 6 лет назад

Thank you so much! You helped clarify a lot of areas that my textbook failed to properly explain.

@lisamathews7971 Год назад

You remind me of an off-brand Dave Grohl and it makes studying way easier, thank you

@jxyz9154 6 лет назад

thank you so much for your explaining

@vidyabhushan4381 6 лет назад

Awesome description!!!!

@akinyemihafsat3699 2 года назад

Wow! I love the lecture. Thank you Prof

@deepseacocoon 6 месяцев назад

This man has Taught me for 3 separate courses, its amazing

@dafidtaylor 7 лет назад

great refresher vid, great name

@anonymousplayer6378 Год назад

Sir, can you state the difference between DNA polymerase alpha beta, gamma, delta,epsilon and DNA polymerase 1,2,3??

@shaistanazir8752 7 лет назад

it was beautiful sir. it helped me memorize it smoothly.

@boscokimbawala1053 Год назад

Thank proff Devi .....am really enjoy your session

@jinkedewilde4792 6 лет назад

Thank you for saving my exam! Very clear and well structured explanation.

@irinabains4300 3 года назад

hi prof, had a few doubts: 1. after binding the primer to the DNA strand, the primase leaves the spot, and DNA polymerase iii takes the same spot to start adding the free DNA nucleotides? 2. on which strand do the following take place first or do the following processes take place simultaneously (as there is one molecule of enzyme allocated for each strand?) on both the strands? a) exonuclease removing the RNA nucleotides/primers b) DNA polymerase I adding DNA nucleotides in place of the primers c) Primase adding primers d) polymerase III adding free DNA nucleotides

@ayushijain8671 7 лет назад

Well explained. Thanks!

@sunehrikiran5638 6 лет назад

great as always .

@tylergoh2287 3 года назад

I love u Prof. Dave , u made it simpler

@sarajakobsen1070 3 года назад

Its so frustrating, I understand the protein syntecis, the DNAs structure, mitoses and meiose, transcription, translation etc. when I get it explained to me, but there is no way I can repeat it😂😭

@anjaliiiraaa1 6 лет назад

Thank you so much sir.... It really helped✌️👌

@Zetsuke4 4 года назад

I can leisurely watch Professor Dave in my free time and enjoy every second learning as many videos as I can.

@memunaissah823 Год назад

You’re a life saver Professor Dave..

@DyanaBunnyPhD 2 года назад

From Professor to Professor 👉🏼 you are great !!!

@Toothfairy1018 7 лет назад

you're the real MVP! and I love your intro lol it's hella catchy and cute

@Sciencegurukul108 6 лет назад

Nice explanation..

@MohammedSadeq-gz4el Месяц назад

Thank you couldn’t understand from the biology book with the diagrams you just made me understand in 6 minutes

@TKenziefied 2 месяца назад

thank you so much, i am so grateful for this video. Explanations are perfect.

@shayekhabedin4462 3 года назад

If only I had you as my lecturer ! Absolute legend mate!

@damerababu1476 5 лет назад

Easy understanding explanation

@jezrhaymagayones8841 Год назад

I like the fact that what I learned here was better than what I learned in school, more detailed and compact Keep it up 😊

@anber4129 5 лет назад

Very detailed. Thank you very much! ♥️

@Mary-gr3mr 3 года назад

You're a good man Dave!!! Thank you thank you !

@domzy27ko 4 года назад

Thanks professor. Such helpful video

@vidyabhushan4381 6 лет назад

Great work sir

@ioannis9498 6 лет назад

Thank you! Very helpful! Which okazaki fragment will be placed first in the lagging strand?

@kimia1664 5 лет назад

I got more than I asked for! A lot of these stuff aren’t part of my textbook but I don’t care. I’ve always wanted to learn this anyway.

@maral3828 3 года назад

thank you for your great explanation

@onefriendlyduck7768 8 месяцев назад

Thank you, Dave!

@alvinwong9281 3 года назад

nice explanation!!

@elliemcanuff8157 6 лет назад

holy shit i've been looking for videos like this all year

@ProfessorDaveExplains 6 лет назад

search no longer!

@italianfire110 5 лет назад

This is the only video I've seen that accurately explains the difference in role of Topoisomerase and Helicase...Thank you

@alderamin1402 2 года назад

Amazing explanation

@mdkgaming3632 7 лет назад

Thank you was very helpful with my project

@pradeepajayanetti7500 3 года назад

This video is perfect thanks a lot sir.

@nadiasotelo6045 6 лет назад

Really helpful!

@mohammadmonir6771 2 года назад

Well explained!!

@Arvatly 3 года назад

Dave, polymerase III reads from 3' to 5' but polymerases new strand from 5' to 3'? But you said polymerase copies 3' to 5'. Did you mean polymerase reads 3' to 5'?

@ProfessorDaveExplains 3 года назад

I said moves along the template strand, so yes "reads" would be a good way to interpret that.

@tcinca168 3 года назад

Thanks for the help. Now I get DNA replication better than ever!

@MyDerpDerpDerp 7 лет назад

As was stated previously, the direction is NOT 3' -5'. According to Mc Graw-Hill 11th ed. Biology, "As with all known DNA polymerases, all three of these enzymes synthesize polynucleotide strands only in the 5'-3' direction and require a primer"

@ProfessorDaveExplains 7 лет назад

i meant that it moves along the template strand 3'-5', though you are correct the new strand is synthesized 5'-3', perhaps i should have been clearer in the animation.

@MyDerpDerpDerp 7 лет назад

Thank you for your timely reply! Perhaps it could have been clearer, but you are right as well. Thanks for the video, anyhow :D

@LullubiKURD 7 лет назад

Thank you.

@Ben-kl8do Год назад

Not sure if nitpicky or not but it could help to clarify that DNA polymerase III/I are those used in prokaryotes. I remember in high school still using the terms generically but I believe DNA pol-alpha/delta are the current standards for eukaryotes?

@spiritwing9391 4 года назад

Whenever I am in need of help in biology, I go to this dude! Nice job! 👍🏻

@spiritwing9391 4 года назад

Thanks for hearting!

@trafalgar22a8 6 лет назад

Thankyou Professor. My grandson has WAS and I want to learn how to repair denovo mutations. I am familiar with Jennifer Doudna's work but she tells me that gene therapy is yet immature. Rgds from Australia 27MAR2018