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Dominic D'Agostino, Ph.D. on Modified Atkins Diet, Keto-Adaptation, Ketosis & More 

FoundMyFitness
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7 сен 2024

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Комментарии : 626   
@FoundMyFitness
@FoundMyFitness 6 лет назад
Get the show notes and transcript! www.foundmyfitness.com/episodes/dominic-dagostino
@kurtevh2
@kurtevh2 6 лет назад
I am a couple years late here, but here's something new, Metformin is sold as a drug but it is actually more nutraceutical, "G. officinalis called guanidine, which could lower blood glucose levels in animals but was also toxic. Chemists found that they could make the compound more tolerable by bonding two guanidines together, forming a biguanide" Here's the link, great talk by the way! First video watched, but already a fan, cheers from Brazil! > www.diabetesforecast.org/2010/dec/the-origins-of-metformin.html
@livehealthyfinishstrong
@livehealthyfinishstrong 3 года назад
Thanks for this! My life has been transformed by this sort of information. I am turning 65 and for the past 2 years I have combined LOW CARB (Keto) with Intermittent Fasting, lost 82 lbs., came off ALL MEDICATIONS (2 for hypertension, one for high cholesterol and gave up my CPAP for sleep apnea). I am Loving life! I started my own RU-vid channel “Bill C Thompson - Live Healthy, Finish Strong
@theramseyclark
@theramseyclark 8 лет назад
Dom is such a nice well-mannered guy. He's also leading the frontier!
@archivemail7710
@archivemail7710 7 лет назад
Nice intended helpfulness of the show. He is such a careful listener and patient diplomatic responder. He clearly is a humble guy.
@EddieStriked
@EddieStriked 8 лет назад
THANKS for all the hard work Rhonda. There's a lot of crap podcasts out there today but yours truly stands out.
@FoundMyFitness
@FoundMyFitness 8 лет назад
+Eddie Strike Thank you!
@billytheweasel
@billytheweasel 8 лет назад
+Eddie Strike The pop-up definitions are perfect for where I'm at. They top it all off perfectly.
@Trendle222
@Trendle222 7 лет назад
i thought i knew a lot about Health and everything (been really studying how the body works a lot past several years) and ya'll are just blowing my mind ! this is something im gonna have to listen to a few times to let it all sink in. I Love being challenged mentally =) Keep up the awesome work Rhonda =)
@samualwhittemore228
@samualwhittemore228 7 лет назад
Eddie Strike I love Rhonda Patrick! She always has info packed interviews and presentations. Two thumbs Up!
@makalasipes9339
@makalasipes9339 6 лет назад
Eddie Strike would you kind to try keto?
@NomenNescio99
@NomenNescio99 8 лет назад
The intellectual honesty both of you display when you clearly state what you don't know, the way you separate speculation from facts and perhaps most of all - the curiosity to learn more - which is clearly visible in the interview are all things that I find very admirable and respectable. Thank you for a very interesting video.
@george2784
@george2784 7 лет назад
One obvious side effect of a ketogenic diet is the ability to perform an almost 180 degree man spread. Keep it up doc.
@jennybtx
@jennybtx 6 лет назад
george2784 Haha!!!!!!
@wellnative1
@wellnative1 6 лет назад
LOL!
@MiroBG359
@MiroBG359 6 лет назад
and having huge thighs :)
@sethweber2224
@sethweber2224 6 лет назад
Hahaha
@patw1426
@patw1426 6 лет назад
Had to burst out laughing!
@AmericanMuscleMiami
@AmericanMuscleMiami 6 лет назад
I am a keto athlete bodybuilder 51 years old two time national’s qualified competitor in two different divisions this diet has been revolutionary in my success in bodybuilding
@zamplify
@zamplify 6 лет назад
I love the footnotes. They make this super high-level conversation accessible. Thanks, Rhonda!
@justpete4225
@justpete4225 8 лет назад
I cycle ketosis, 4 eggs low fried swimming in coconut oil breakfast and filter coffee with butter (grass fed) and mct oil, then intermittent fasting during the day, then lots of high fibre veggies, lots of broccoli covered in more grass fed butter, and grass fed beef and some fruit in the evenings. So far, 2 months on, my eyesight has improved to the point where I no longer need my glasses to use the PC at work (i've been there 8 years and needed glasses the whole time!), and my fingernails look 100% better and I have tons of energy and sleep like a baby! Its all good! I went out for a jog after the first month (my first jog in 7 months), fueled only by the breakfast above and ran 6.5 miles, the longest I've run in training since my 20's ....20 years ago. Research it then Try it people!
@broccool2300
@broccool2300 8 лет назад
+Pete Farrow What was your diet like before this diet? Do you eat the same thing for breakfast and dinner everyday?
@michaeljmcdaniel
@michaeljmcdaniel 8 лет назад
+Pete Farrow seems off since ketosis takes a few days to activate.
@justpete4225
@justpete4225 8 лет назад
elephant For about a year before I was eating about the same thing, whole foods, plenty of eggs, veg, fruit, grass fed and patured meat etc. The main difference now is the order in which I eat and adding the butter and mct oil in morning in my coffee. Another change is, I used to drink instant coffee with milk during the day which I have swapped with green tea. I eat the same breakfast every day, then nothing (fast) during the day, then evening meals may vary, but is usually clean meat and veggies and if I'm still hungry I'll have fruit or a green and fruit smoothie. I'm not too strict with evenings, as long as there are veggies and clean whole food.
@justpete4225
@justpete4225 8 лет назад
Michael McDaniel From what I've seen it takes different people different amounts of time to adapt be able to get into ketosis easily. The less high insulin spiking foods (breads, cereals, rice, processed foods) you eat in general, and the more quality high fats you eat in general (when not in ketosis) will make it easier to go into ketosis. Also, how much and the type of exercise you do will make a massive difference how quick you can get into ketosis.
@justpete4225
@justpete4225 8 лет назад
Mikko Finell​ There are no hard and fast rules. The benefits of fasting start after insulin levels drop to their steady resting state after your last carb meal (which is 3 hours), with human growth hormone being insulins hormonal opposite, hgh levels rise from then after. But with a 0 carb breakfast I can only surmise this will happen much earlier, and actually pick up quite soon after my breakfast with a reasonably minimal interruption. Plus of course, the benefits I get from consuming high fat after my 10 hour sleeping fast are that of ketosis. Doing this daily will mean by now I am keto adapted, and will jump into ketosis and still be able to eat carbs evey night to get my fiberous veggies and their benefits. The way I feel during the day, and the fact than I can hit the gym and do a full workout after the days fast speaks for it self to me. I do x2 10 hour fasts (give or take), only broken in the middle by eating a 0 carb meal, and as stated by in the vid, the benefit of fasting and the benefit of ketosis share many similarities. Which ever way you look at it, this is clearly working for me...and it is now an effortless part of my life.
@ultimatebjj
@ultimatebjj 2 года назад
Revisited this amazing interview from 5 years ago. Very interesting, especially in light of the fact that Rhonda has recently (2021) adopted the Ketogenic lifestyle. Would love to see them do another interview.
@mrclean2022
@mrclean2022 8 лет назад
Pretty sure I had a nerdgasm seeing these two have a conversation. I love and respect both of these brilliant individuals! Very nice touch on the captions too! Thanks for sharing :D
@mrclean2022
@mrclean2022 8 лет назад
@105359006577168407301 Yea it really is, especially since governmental health organisations have been demonizing fat since the 80s. Have you ever tried following a ketogenic diet before?
@nevertestELOHIM
@nevertestELOHIM 3 года назад
Nerdgasm loooooool🤣🤣
@Jason-bg7jc
@Jason-bg7jc 8 лет назад
I love hearing Dom speak because his vocabulary is like 10 levels above mine. Getting you two together is like exploding my mind.
@NYNYDuelingPianos
@NYNYDuelingPianos 8 лет назад
Rhonda, Dominic...you two are gangsta! Seriously enlightening conversation. Dominic: you never got to answer Rhonda's (almost) question near the beginning about the types of fats in your current diet. Do you differentiate between Polyunsaturated, Monounsaturated and saturated fats when choosing fatty foods to eat? Do you eat less Omega 6's...do you eat fatty foods indiscriminately? Is there a profile you aim for in that part of your diet?
@angeliquegilbert7325
@angeliquegilbert7325 5 лет назад
Rhonda, I'm only twenty minutes in so Dr. D'Agostino may begin addressing this, but you were asking about gut health and ketogenic diets. I was diagnosed with IBS 5 years ago: did a food inflammation test and a strict elimination diet for ALL my triggers, increased my green veggie into to at least 4 cups a day, etc. I recovered about 85% but still dealt with nausea and lack of appetite 2-3x/week. I've been on modified ketogenic diet for about a month and for the past 3 weeks have had zero of those issues. Just FYI!
@CinemaTeacher
@CinemaTeacher 7 лет назад
I understand about 1 millimolar of what they're talking about. Ha!
@samualwhittemore228
@samualwhittemore228 7 лет назад
Roberto Gudino One mole + Avogadro's number = LOVE
@WHK2eZ
@WHK2eZ 6 лет назад
😂😂
@demotheses
@demotheses 6 лет назад
Same
@wilsonsclips_
@wilsonsclips_ 3 года назад
Best comment ever hahaha
@freeandcriticalthinker4431
@freeandcriticalthinker4431 5 месяцев назад
It’s the Concentration of Ketones per unit of your blood. I think it might be ng/mml……? Not sure on that but anyway you need to order the blood kit and Monitor yours to try to kept it north of 1.0 units…..don’t let these jackasses below distract you! They are just complete embolus’s. Like the crabs in a bucket, don’t let those damn destructive children pull u back into the bucket……..
@aone6535
@aone6535 8 лет назад
I love the added notes and definitions during the videos! So useful!
@scottk1525
@scottk1525 3 года назад
18:42 This is the longest, most convoluted version of "I don't know" I've heard in a while lol
@neilsant1194
@neilsant1194 6 лет назад
I can feel the sweet chemistry between this two gorgeous smart people... Why dr.Rhonda is so chic in this talk??? 😍
@qianning3940
@qianning3940 8 лет назад
Rhonda, I like your podcast, it is very informative, especially you gives some important concepts in writing which differentiate yours from others, I can pause the video and read them. This has helped me tremendously in understanding the key points. Thank you!
@europeancavebeast9100
@europeancavebeast9100 6 лет назад
I love listening to these videos. Its a privilege to take in the knowledge of competent scientists / Doctors.
@paulbenton4273
@paulbenton4273 5 лет назад
Initially started keto 2 years ago for weight loss. Pretty much at my weight goal. Will stay on it forever as I had a head injury in 2010 (TBI) and the ol' brain always could do with a little help... Fasting twice a week too.
@dauphinviennois
@dauphinviennois 3 года назад
This is one of the most comprehensive talks, it included everything I was interested, without even expecting it. Congratulations! 👏🏻
@mikemccartneyable
@mikemccartneyable 8 лет назад
Really great talk, thank you for making it and sharing, It was super to hear the subject of nutritional ketosis inspected and questioned from a non-Ketogenic but highly researched interviewer (Rhonda). I am 10 months in keto, it was a hard transition at the start but I have since experienced many, many benefits which seem to just keep coming the more time I spend in ketosis (maybe as mitochondrial gene expression kicks in?). I think the links to cancer prevention/management are absolutely fascinating. I have chosen to remain in ketosis as a life choice (i.e. its not a fad diet for me, its a lifestyle). I haven't tried intermittent fasting yet but I might give that a go at some point and see what the effects are.
@joebobmarley2854
@joebobmarley2854 7 лет назад
I love your interviews Rhonda. So amazing, and life changing to get details of info like this, especially for people that are interested in these subjects and have done research, and their own experimentation, this fills in pieces of the puzzle every time you have an interview.
@user-qu6rd1uv7z
@user-qu6rd1uv7z 3 года назад
Dude is doing some serious man spreading there
@anjabrox8499
@anjabrox8499 6 лет назад
Thank you so much for the written explanation during the interview, that is so valuable!
@simplyphenomenal
@simplyphenomenal 8 лет назад
30 days in CKD diet has improved my life so much already
@rideDApowda
@rideDApowda 7 лет назад
The Insulin Levels shown at 25:25 as normal are insanely high! That is the old paradigma, that made 70% of the population insulin resistant. If you are not below 30 after two hours, you are sick or even doomed. Also DÁgostino talked prior to this chart about Insulin reaction to Protein and not Glucose.
@sunbunker685
@sunbunker685 7 лет назад
Unmeasurably fascinating, you two.. What a great time to be alive :)
@2bluema139
@2bluema139 8 лет назад
Dr. D'Agostino looks like Eric Banna here. A stud with brain!
@mjenk20236
@mjenk20236 8 лет назад
Great conversation with Dr. D. I was afraid that with all the bench work we wouldn't see this for a while.
@djtactician
@djtactician 7 лет назад
Thank you so much. The information and knowledge i have gained from first watching you on the Joe Rogan show has been invaluable and i'm excited to start a keto (modified atkins) diet. After cutting out refined carbs and increasing my fat intake i am already feeling the benefit.
@inhust4881
@inhust4881 2 года назад
I do intermittent fasting. Periodically do 3 days of keto per week, for 3 weeks, then back to low carb & sugar intermittent fasting diet.
@greendeane1
@greendeane1 8 лет назад
I am in the choir with both of you but most ....no... all of the dietitians I have met have got their head deep in the MD-dogma. They are in extreme denial of good saturated fat, quality protein and ketones and are still pushing four or more servings of sugary fruit a day. I think Dr. D'Agostino's advocacy is rightly focused but finding a dietitian who's on the same nutritional wave length is doubtful or at least rare. It sounds like a career opportunity to me but it is difficult to say to a young dietitian "congratulations on graduating but if you really want to help people forget most of what you just learned."
@stefanweilhartner4415
@stefanweilhartner4415 8 лет назад
+Green Deane that's very plausible. cause most people use a mixed food source where carbs are a significant part of the diet also a lot of studies are focused on that. so when trying to find out what fat is probably good or bad it depends on the circumstances around which also means if the tested persons where in ketosis or not. the question also is, how high the insulin level is when processing a high fat diet. maybe that is the key if significant levels on insulin are in the blood or not regarding the health impact if one is on a high fat diet.
@nunyabidness8297
@nunyabidness8297 7 лет назад
I have known more about diet than all of the dieticians I have met with. Considering I studied English Lit in college, that's saying a lot! This is not a brag on myself (I've studied nutrition extensively independently), but a statement of the failure of Medicine to teach about nutrition. I understand nutrition is a new field of study, but as such, it is ever-evolving, and the dieticians I speak with are inflexible or uneducated on new findings. If I had followed their advice, I would have full blown Diabetes by now instead of regressing back to normal, stable blood sugars.
@bhartley1024
@bhartley1024 6 лет назад
Green Deane, Eat the Weeds! I went on some walks with you in Florida. I've noticed that about dieticians too, some of them seem to know just enough to be dangerous. They're stuck over on the left of the Dunning-Kruger curve.
@amandaj1728
@amandaj1728 6 лет назад
If you studied English lit in college, you should know dietitian does not contain the letter "c".
@Photologistic
@Photologistic 5 лет назад
Amanda J - She studied literature, everyone should study grammar.
@Dan-jo8py
@Dan-jo8py 7 лет назад
most people overdo the fat anyway on ketogenic diets; if you bother to look the ratio needed is roughly 2:1 not 4:1 in the founding paper by wilder & winter. which, not surprisingly, is the same ratio you burn at rest internally. which is why keto works, it's not that it does something, it's that it doesn't - it doesn't disturb the fasted energy state, but it allows you to intake calories and not die long term. the only reason they went to 4:1 or higher for children with epilepsy is because they were sick, it was a corrective over-dose for a clinical treatment. the 'new' mct versions, are just actually what wilder & winter found in 1922 - none of the newer methods gets fat intake below 66%.
@derekcarrol8665
@derekcarrol8665 4 года назад
Another podcast from you two would be awesome, please?
@shana.u
@shana.u 8 лет назад
Excellent information. Where would one draw the line between using glutamine to heal the gut, verses keeping it out to avoid feeding cancer cells? In particular, if there is a condition such as intestinal metaplasia either of the stomach or the esophagus or Barrett's esophagus. These are not cancer, but considered precancerous conditions. One would think glutamine would be helpful with healing intestinal metaplasia, but one probably should also know that there is absolutely no sign of cancer prior to supplementation. Seem like a fine line.
@Vinsent1022
@Vinsent1022 2 года назад
excellent information guy, great interview and lots of clarity on many points everyone gets confused on. Keep up the great work, would be great if you can share best methods or places to get tested for various blood markers, Best rgds Si
@bscottc1
@bscottc1 7 лет назад
When he talks about pulsing metformin it reminds me on Ayurveda's emphasis on seasonal adjustment.
@tedb1055
@tedb1055 8 лет назад
Huge difference from fat and protein from good sources verses less desirable sources. Wild Alaskan Sockeye Salmon grilled in olive oil with crushed dill, served with wild blue berries is good. Commercially raised hormone and antibiotic filled meats often are undesirable. Many other examples, however this illustrates the importance of the source.
@markman63
@markman63 7 лет назад
Glad to watch an actual Phd talk about this. There are so many chiropractic "Dr"s on RU-vid who give bad information
@Photologistic
@Photologistic 5 лет назад
markman63 - I’ve never gone to one, but Chiropractors deserve more respect.
@skauffman74
@skauffman74 8 лет назад
Dear Miss; please don't get me wrong on this. As a side note only, perhaps would be best if you can resist the temptation to ask or remark something when a person is developing an explanation. I can understand your high motivation for doing that and I really engourage it; just a little more room for the interviewed to finish the idea. A sincere and constructive point of view. Keep up the good work. Greetings.
@samualwhittemore228
@samualwhittemore228 7 лет назад
Sergio Kauffman Acosta ARE you kidding? Her questions may be a bit tangential but very pertinent to the topic at hand. BESIDES --> She is the interviewER, not -EE.
@craigedwards2557
@craigedwards2557 6 лет назад
Your Wrong MR & don't get me wrong on this but it would probably be best if you can avoid the temptation to remark or ask something "like your comments which really are nonsense....couldn't be further from the truth" when Doctors such as Rhonda who knows her stuff & Dominic engage in a very fact based conversation dialogue...really know their stuff- probably be best for you not to comment at all , we sense a patronising condescension to your comments which does not reflect well on you! Hope you don't mind us pointing this out to you as you sound maybe a little drunk when you left these comments....apologies if this is the case we all do say unintelligent things when we drink
@llorensfriedapembrook5149
@llorensfriedapembrook5149 6 лет назад
I wish she didn’t interrupt him when he was explaining.
@dingdongbell32
@dingdongbell32 6 лет назад
Agree with you 100%. Twice she asked a question or made a comment then cut him off while he was attempting to answer
@KimikoMaui
@KimikoMaui 6 лет назад
It's hard to follow at times but I love the points she brings up. I have the same questions she has and wud want to go on "tangents" in order to truly learn something well
@daveoatway6126
@daveoatway6126 7 лет назад
So refreshing to hear scientific analysis from real scientists instead of the typical amateur weight lifters or pseudo scientists like chiropractors The issues are much more complex than most presenters seem to comprehend. The discussion of risks and dose related effects (hormosis) is excellent. Some the personal experiences are helpful.
@TheMystery51
@TheMystery51 7 лет назад
What about those skinny raw vegan girls on youtube pushing veganism? Haha
@natrium777
@natrium777 7 лет назад
This is amazing. Both of you found in one podcast --- makes my day, hell, it makes my year
@ronaldphillips5481
@ronaldphillips5481 6 лет назад
I went on the ketogenic diet using lard butter beef fat and all the other animal fats , My stomach could not cope with coconut oil mct or olive oil and i have had great results so people don`t worry to much eat what fats you can don`t get to tied up in scientific dogma.
@toddwinton5025
@toddwinton5025 8 лет назад
High quality information. Thank you.
@ten10zinG
@ten10zinG 4 года назад
10 minutes into this and I've already taken so many notes!
@PhuPhillipTrinh
@PhuPhillipTrinh 8 лет назад
Love the detailed captions! Keep up the great work! Even a non-science guy like me can keep up.
@JerzeyBird
@JerzeyBird 8 лет назад
SO glad you asked the question about glutamine supplementation! Great interview
@hotmojo1
@hotmojo1 8 лет назад
This discussion beats a bong hit any day. Thanks, guys! Now for a homemade, medium chain fatty Keto shake, blended with fermented vegies for a liver-gut holiday.
@commentsquestions1820
@commentsquestions1820 6 лет назад
Can Dom or some provide more detail about carb intake? If you're measuring carbs on a total basis, it's very difficult to maintain. If you're netting dietary fiber against carbs, then it's doable. Please discuss.
@The1RobynHode
@The1RobynHode 8 лет назад
Study sunlight assimilation on these mechanisms. You'll be shocked at your results. I've been on Keto for 6+ years and I can tell you if I'm missing sunlight in my weekly routines, everything falls to crap. I've been extremely glutamate-sensitive in the past, and I can tell you sunlight is the best mitigator for calcium effluxing. Heme is a photoreceptor... just compare the molecule to chlorophyll to get your answer... it's a solar panel; it's why it rises to the surface in skin to convert cholesterol to vitamin D (one hydrogen molecule difference), so you miss UVB and IR from the sun, you miss out on a lot of energy assimilation. The protocol Dominic mentioned is a semi-fail with IF+Ketosis (which I was attempting in 2012-2014) because it can lead to salt-imbalance, leg cramps, etc. unless you really know what you're doing. It does shave off the bodyfat like no tomorrow. But I found doing a big breakfast high protein/fat, moderate lunch and light dinner aound 5pm for about a 12 - 15 hour fast daily. If I push the IF window too long I've found in the past, it can push my blood glucose too low around 3-4am to wake me up, especially when exercise intensities from the past day were stronger.
@The1RobynHode
@The1RobynHode 8 лет назад
+The1RobynHode Yes, look deeper into the quantum physics with electron and proton tunneling at the inner mitochondrial membranes. My take listening to your podcast is that you're focusing too broad on the biochemical processes when there's more being driven by the physics. Go read some Jack Kruse... he's going to blow your minds. DHA concentrations, 4th phase of water Gerald Pollack, etc. I'm telling you as a biologist myself, mind = blown. He also answers disease entirely in my opinion and what I've seen with disease formation... when you learn about light wave functions and electromagnetics what he calls nnEMF, you unlock all of the keys to our biology for causation.
@rationalrand
@rationalrand 8 лет назад
+The1RobynHode Great post... I went to your youtube site and watched your video about fat. Good work and excellent testimony. Do you per chance know exactly how are ketones metabolised and how much energy do they produce or (rate of production)? This answer is hard to find. While we are at it we can ask the same question for aerobic lactate metabolism. Thank you,,,,,
@The1RobynHode
@The1RobynHode 8 лет назад
+rationalrand For ketones, I believe what you are looking for is FAD at the mouth of Cytochrome Complex II using the FE-S electron tunneling mechanism. Other cytochrome complexes may be involved also. You have also stumbled into semi-interesting territory because the math for reactions don't completely add up. It may be because of ROS (reactive oxygen species), or how easy or not electrons are able to shed within the mitochondria. Hypothetically thinking about how a battery works, if the mitochondria isn't working optimally due to various state/conditional changes, one would believe there is variability built into the energy production.
@rationalrand
@rationalrand 8 лет назад
+The1RobynHode Interesting, Do you know what the rate of ATP production is? In reference to a runner. Thanks,
@The1RobynHode
@The1RobynHode 8 лет назад
+rationalrand I think the evidence is still being collected and analyzed. The short answer is that it's ongoing science because of the conditions and processes involved. There are many light-based mechanics that come into the equation left out by most mainstream opinion rooted in past science. I like to follow the current scientific ideas. ATP production is generated via what mitochondrial complexes are activated and the efficiency of electon tunneling. To know the efficiency of ATP, the question to ask is do you know how charged the electrons are in ECT? Carbs are metabolized in cytochrome 1 with NAD, where fats are in cytochrome 2 with FAD. Fats carry more electron density vs. carbs, so it makes a lot of sense why low-carb and ketogenetic diets have been so beneficial, but, if they are misused and the mitochondria themselves are not able to regenerate well due to the environment they are in, heteromplasmy rates may increase. In ref to a runner, this is why it's semi-complicated to answer because of the dependencies of the mitochondrial charge coming into the ECT based on how well that charge can be held within the inner mitochondrial membranes. Personally I believe that Gerald Pollack's work is pretty crucial to get a grasp of and a big missing piece of the puzzle among mainstream folk, because of how water can behave within these types of surfaces... in other words, if an exclusion zone of H3O2 (not H2O because a lattice can be formed near tissue structures) can be formed and maintained, energy output is directly influenced. This gets back to how we are properly using light wavelengths or misusing them. A lot of people forget that microwave, radio, cellphone, wifi and even heat are all forms of light, and most of this EMF penetrates our tissues easily. The environment you put your mitochondria on a continual basis therefore matter to the energy you get out of them.
@sharris7310
@sharris7310 5 лет назад
Rhonda, after speaking with Dominic D'Agostino, I would love to hear your opinions on trying a ketogenic diet. As evidenced by your famous smoothie recipe, you have never promoted a high-fat, low carb diet. Has your approach changed in any way? Even though I respect Dominic D'Agostino, I do not believer a diet based on 80-90% could deliver the benefits Dom describes. Would be interested to hear other's perspective.
@preciousfreedom1159
@preciousfreedom1159 8 лет назад
Great video- been following D'Agostino for a while now. Thanks! I am proof that you can be on a plant based, high fat diet and stay in ketosis :D It's wonderful so far.
@BrandonEsparza04
@BrandonEsparza04 8 лет назад
What are your main higher fat foods? Seems like it would be difficult. I'm primarily plant based but am really interested in doing this.
@J.Allen_
@J.Allen_ 8 лет назад
Fish, Butter, Coconut, Avocado, fatty beef, fatty pork, eggs, sausage, olive oil, olives, nuts...remember that you want 2x as much omega-3 than omega-6. So limit (veg oil and nuts etc).. We get so much omega-6 by accident that it's generally too much already. Stay away from them. I tend to steam a TON of veggies and use a mix of butter and olive oil all over them. Then add a little meat/protein (almost as a side dish portion-wise).
@preciousfreedom1159
@preciousfreedom1159 8 лет назад
John Allen mmmmm veggies
@markgerard2
@markgerard2 6 лет назад
Just about all the really good sources of info on the web about doing keto advise some sort of modified Keto diet..Makes sense given we are all very different. I would say start strict then make small changes and register the results scientifically over 12 months.. Strict Keto gets you really good results quickly and its very motivating, but takes 8-12 weeks to be comfortable. So i would advise get to 3 months prior to making the small changes..I turn 50 this year and I'm now 9% body fat much lower than i have ever been (in my whole life) and i work in fitness. I still drink wine on the weekend and cycle carbs around my workouts but it took time for me to do this and find my boundaries, and how to bounce back to KETO in 12-24hrs..Never felt better..:)
@jaybird6034
@jaybird6034 5 лет назад
Two high functioning brainiacs unbelievable podcast lots of great info I wish I understood more
@Marco-jx9rr
@Marco-jx9rr 6 лет назад
The only diet that increased a lot my triglycerides and LDL cholesterol was the vegan wfpb starch and fruit diet with zero fats added. What a mess for my blood, almost worse than a standard casual diet
@michaelputnam3216
@michaelputnam3216 7 лет назад
Very very interesting and impressive vid. Rhonda I am going through your vids making notes. Truly inspiring and so relevant ☆THX♡
@victoriap2519
@victoriap2519 4 года назад
With cancer cells all comes down to evolutionary biology Zenger's: One wouldn't expect the immune system to recognize a cancer cell because it's self. Dr. Stefan Lanka: That's it. We have a lot of embryonic cells in our body all over. Those are the stem cells. When the nerve cells have got broken, new nerve cells may regenerate out of the embryonic cells, because those cells cannot be regenerated. So we have embryonic tissues everywhere, and here comes evolutionary biology. Now I have to tell you the basis of our lives. The fermentation process was not producing enough energy to form multicellular organisms or to enable the cell to differentiate. Bacterial cells are not differentiated, not able to build multicellular organisms because they don't have enough energy. Only the invention of photosynthesis -- using the energy of the sun to split down matter in order to get electrons -- allowed life to go on. Life is driven by the force of electrons, and with photosynthesis the electrons came out of the splitting of the water, and the base product was oxygen. This photosynthesis was so successful that it polluted the whole planet. The water, and eventually the atmosphere, became saturated with oxygen. Only when bacteria began to learn to use oxygen to produce much more energy out of organic material, out of a sugar molecule, did we have the next step in evolution. Life dealt with the oxygen catastrophe, and since then we have had a perfect equilibrium of oxygen-producing bacteria and oxygen-using bacteria, so that they keep the atmosphere at a constant level of 20 percent oxygen. This is exactly the level at which life is able to persist. At a lower level, or a higher level, it is impossible. We are living in the equilibrium. That's the principle of Gaia, by the way. Those bacteria which learned to use oxygen were able to produce 20 to 30 times more energy per sugar molecule, because the oxygen at the end was sucking so many electrons that many more electrons could be taken out of the sugar, to produce much more energy than was possible without the potent oxidative substance at the end of the energy-producing chain. This revolution in energy formation was the basis for all higher cells and all higher organisms. Of course, with this excess of energy, cells could eventually differentiate and form multicellular organisms. And these bacteria, which sere using the oxygen, are part of every one of our cells, called mitochondria. So very higher cell is a product of the fusion of several different kinds of bacteria: the spirochetes, which brought mobility into life; and the mitochondria, which produced much more energy than before. This excess energy is the basis of all higher life, and if you violate it -- if you don't let the oxygen come into the organism; if the blood is oxidized by poppers [nitrites] or sulfinamides [including sulfa drugs like Bactrim and Septra]; or if the transit way between the blood and the cells is poisoned by heavy metals, or the lack of essential fatty acids; or when the mitochondria are destroyed in the cells, due to the lack of nutrition, or antibiotics -- the oxygen cannot be transported from the blood to the cells. Then the cell is not able to produce enough energy. It either may die, resulting in inflammation; or when it's possible for a cell to survive, it will become cancerous. When the cell is producing only fermentation, then that's cancer, as Otto Warburg already detected in the 1940's. They knew from the very beginning that cancer cells have only embryonic markers on their surface. From a biological, evolutionary point of view it makes sense that a cancer cell is a reduction to an embryonic stage. It de-differentiates due to the lack of energy, and it waits until the lack of energy is over in order to differentiate again. Of course, if the lack of energy persists, it loses genetic material; and these were the old criteria to define cancer, when cells lost a lot of genetic material, because then they lost the ability to differentiate again. Zenger's: In other words, cancer occurs when the cell is programmed to behave like a cell very early in fetal development and just divide like crazy. Dr. Lanka: That's it. An embryonic cell goes into a unicellular state. It behaves like a unicellular organism, like a bacterium. It loses the ability to stop replication when coming into contact with other cells. So knowing about evolutionary biology, you are able to explain everything. In order to explain failure to find a retrovirus that directly caused cancer, they claimed to be able to measure the immune system. But this is ridiculous. In the Journal of the American Medical Association, August 28, 1981, it was published that it makes no sense to measure lymphocytes in the blood because only a few of them are in the blood. The immune system is carried out, not in the blood, but in the tissues. Only rarely and accidentally do we see some of them in the blood. We've already carried out thousands of studies which have proven no correlation between disease or health, in old or young, in T-cells; and even less, of course, in T-cell subsets. But, even though they knew that these T-cell tests had not meaning, they were selling them to the market. Beginning in 1977, starting in the United States, it was possible to patent biological entities or biological techniques, so people started to make money out of biological ideas. This is the definite turning point when modern medicine and modern biology lost their 'Unschuld', their innocence. That's it. The immune surveillance theory of cancer -- the belief that if you measure the strength of the immune system, then you could see when you are going to develop cancer -- was the basis of AIDS, the thinking about AIDS. They said if your immune functions are weak, you are going to develop all viral forms of opportunistic infections and all forms of cancer. And this never happened, as a matter of fact. In AIDS we never have seen opportunistic infections. We have never seen all viral forms of cancer; only one form of cancer, KS [Kaposi's sarcoma].
@22mononoke
@22mononoke 8 лет назад
Absolutely loved this! Thank you for posting
@seo.schweiz
@seo.schweiz Год назад
The Atkins diet is a low-carbohydrate eating plan created by Dr. Robert C. Atkins in the 1960s. It is a popular diet that focuses on restricting carbohydrate intake while emphasizing high protein and fat consumption. The goal of the Atkins diet is to shift the body's metabolism from burning carbohydrates for energy to burning stored fat.
@sandymitchell6312
@sandymitchell6312 4 месяца назад
He is so knowledgeable.
@michaelschmidt6997
@michaelschmidt6997 8 лет назад
Thanks for a great podcast. I recently also listened to the Bulletproof podcast with Dr. Richard Veech, MD, PhD. Ketone researcher for the last 30+ years. He mentioned that supplementing with ketone esters/salts is less than ideal because you need to get 150G of salts into the blood stream, which is way too much. He mentioned attaching betahydroxybutyrate to 1 3 butanediol is a better option but prohibitively expensive. I would love to hear your thoughts on this. Thanks very much.
@ChadCilli
@ChadCilli 8 лет назад
+Michael Schmidt 1,3 butanediol is also a pharmaceutical, so they would not be commercially available the way that ketone salts are. Worth noting, Dr. Veech has a patent for a non-racemic BHB ketone ester, so it would behoove him financially to steer people away from ketone salts in order to promote his own upcoming product release.
@stellarblur
@stellarblur 5 лет назад
Its likely best to intermittent fast, With mixed in long fast, Eating Mostly plant based carb diet, Beans,greens,berries nuts, With long periods of ketosis from fasting
@bscottc1
@bscottc1 7 лет назад
Also I love the definitions you throw up on the screen Rhonda. Very considerate.
@Lovelandmedicalclinic
@Lovelandmedicalclinic 7 лет назад
I would really love to know how the amount of your protein consumption affects you mTor and IGF levels. Why would periodic spikes in ROS not be good ? Too bad you flashed lab values for fasting insulin being less than 25. I expect my patients to be under 5 . You are brilliant and I appreciate your work
@samanthaleebarrell9141
@samanthaleebarrell9141 8 лет назад
this blew me away i will be rethinking and replanning .
@vonitam1
@vonitam1 8 лет назад
Just in general. had basic bloodwork done at my last physical. But morning fasting since they also checked my cholesterol.
@user-gd7mr5bx1l
@user-gd7mr5bx1l 8 лет назад
Dr. Rhonda, Dr. Jeffrey Tice made a supplement presentation at UCSF and he concluded the following after analyzing several studies: - Omega 3s: no benefit - Vitamin D + calcium: daily for older/frail patients The presentation is on RU-vid and it's titled "Vitamins and Supplements: Less is More".
@CHRISTIANNWO
@CHRISTIANNWO 8 лет назад
Holy crap! I forgot I subscribed to Rhonda Patrick!
@FoundMyFitness
@FoundMyFitness 8 лет назад
+CHRISTIANNWO How could you!
@TheIntelligentView
@TheIntelligentView 6 лет назад
One of the best coffees is 'Cafe Sonora'.
@Appleblade
@Appleblade 6 лет назад
That explanation for how cancer cells are created ... at 1:10:15 ... is nice and clear. People perhaps don't know that there are a number of ways to increase mitochondria in your cells ... both size and number (at least in muscle cells, and perhaps there's an indirect effect for creating mitochondria elsewhere). For muscles, you go high rep, light weight, continuous tension lifts (continuous tension to acquire anaerobic stress) . I believe the magic bullet is 90 seconds (because Fred Hatfield in his book Scientific Bodybuilding set the rep range for targeting mitochondrial growth at 15 to 20 reps ... 6 seconds per rep). Also, Basis, a product you can by from Elysium Health, is aimed at increasing NAD+ ... it on average increases NAD+, which we lose as we age, 40% in test subjects ... NAD+ increases mitochondrial function in mice: science.sciencemag.org/content/early/2016/04/27/science.aaf2693.full
@juhliwoodpath9465
@juhliwoodpath9465 8 лет назад
There was a lady in the resthome who told me her glands were all falling apart due to long term Metformin. Here is a case study worthy of consideration since she had taken it for decades. I thought it had protective factors, but I listened closely to this lady. appx 1:14 in.
@RomanAdar
@RomanAdar 6 лет назад
I'm listening with great interest to this presentation.Just recently I was diagnosed with Lou Gehrig or ALS disorder. In this regard I wanted to ask if you've had any experience treating an ALS with Ketone type diet? Thanks for sharing.
@BlockheadJiujitsu
@BlockheadJiujitsu 8 лет назад
Just finished semester 1 in year 1 of nutrition science and I'm able to mostly keep up with this conversation. So incredibly interesting and easy to listen to as far as conversation flow. 2 good looking people makes it even easier. No wonder it's such a popular podcast!
@chetroman6196
@chetroman6196 8 лет назад
Associate Professor not "assistant"
@OliveLeafandHoney
@OliveLeafandHoney 8 лет назад
Thank you for posting - some very good information to digest here. Would love to hear more on what the Ketogenic diet does to gut microbiome health. Would also like to know what you think on the GAPS diet (if you've heard of it)?
@cramer-family144
@cramer-family144 8 лет назад
+OliveLeafandHoney The ketogenic diet may consist of many types of foods. The one product that is known to help gut microbiome is Coconut oil. Coconut oil is an excellent “anti-biotic”. The Lauric Acid kills bad bacteria and fungi and promotes good intestinal flora. I use this as one of my main sources of Saturated Fat.
@brendaelassal9115
@brendaelassal9115 4 года назад
This is not for the layperson!!!!Two doctors speaking to each other.. Having a private conversation..
@chrislemieux2747
@chrislemieux2747 4 года назад
His "equipment" was totally exciting.
@thomasrobinson2639
@thomasrobinson2639 8 лет назад
Rhonda what are your thoughts on 'How Not To Die' by Michael Greger. I would love to hear you talk about whole-foods plant based diets vs Keto - just because they both seem to argue to do the same thing, however plant-based would say to avoid meat entirely and has a large expanse of evidence for it. Does Keto have the same? Except for weight loss and children with epilepsy. I try to study these things myself, but it would be great to hear it from a nutritionist perspective.
@risknotdonot
@risknotdonot 7 лет назад
Thomas Robinson + concur i will lookup Michael greger now
@blazonish
@blazonish 7 лет назад
Since it's been shown that ketones can be used for fuel in the brain, is there any reason this would be favorable? Like is it as efficient as glucose or will the brain not function quite as well on ketones than it would with glucose as a fuel source?
@erix43
@erix43 8 лет назад
Ronda, loved you on Joe Rogan! You are so knowledgable and AWESOME!
@mexxal16
@mexxal16 8 лет назад
hi, does anyone have any experience with the impact of a ketogenic diet on concentration levels,duration/brain performance/effects on ADHD,ADD? would love to hear some input on that
@anonymoususer7606
@anonymoususer7606 4 месяца назад
I’m person convinced that eating high fat keto is good for my health. But curious on whether endo toxin worries have been answered?
@MichaelNunya
@MichaelNunya 8 лет назад
He showed her some cool equipment she had never seen before.... I couldn't resist.
@GanTreFTW
@GanTreFTW 6 лет назад
jetpack42 😂😂😂😂😂😂
@DaDailyBread
@DaDailyBread 5 лет назад
Michael he also said that’s a “BIG THRUST” of his lab ... 😂
@mathewCPA
@mathewCPA 4 года назад
Nutritional keto is very high fat, low protein, regular keto can be high protein. Ketosis simply occurs from lack of carbs, it's very possible to be in ketosis on a high protein, low carb diet.
@jasondames7210
@jasondames7210 8 лет назад
I love this information!!! :-)
@kyan7232
@kyan7232 7 лет назад
There is a lot of chemistry between you two!
@neilsant1194
@neilsant1194 6 лет назад
Kyan K i comment same thing.... until i scroll down & read your same comment...
@GanTreFTW
@GanTreFTW 6 лет назад
Kyan K yeah he should definitely hit her
@machinesandthings7121
@machinesandthings7121 6 лет назад
People click when they speak the same language. Or another way to say it is when your work and thoughts are appreciated you connect.
@Knic797
@Knic797 6 лет назад
She just had her first baby with her husband not long ago.
@blowera1
@blowera1 6 лет назад
because they're both scientists ;)
@AngelOne11
@AngelOne11 8 лет назад
How to modulate the gut reaction to high fat diet and reduce the production of endotoxins?
@MLouah-gp9ef
@MLouah-gp9ef 5 лет назад
AngelOne11 eat your own crap really works apparently
@amorfati8414
@amorfati8414 8 лет назад
This dude looks younger in every video he appears in.
@stevediben7900
@stevediben7900 7 лет назад
If by younger, you mean thinner...
@Nilsosmar
@Nilsosmar 6 лет назад
Leaner, mentally sharper, more energy, mental clarity...
@zakblue
@zakblue 6 лет назад
keto diet does that man.
@findingnory
@findingnory 3 года назад
@@zakblue well your precious keto diet is not stopping his hairline from receding lol
@zakblue
@zakblue 3 года назад
@@findingnory no diet does
@theresesongalia5163
@theresesongalia5163 3 года назад
My only regret is not trying the Agoge diet earlier, very good results. Keto really ruined me for a couple of weeks before that.
@montycora
@montycora 2 года назад
What is this Agoge diet thing? Would you care to explain? Don't give me what it's good for, I wanna know what you eat in it and what is the logic. I tried googling it and only got BS
@howzaou812
@howzaou812 8 лет назад
Loving your videos, I like the style of the back and forth conversation with added annotations. And you are beautiful!!
@Shreds111
@Shreds111 8 лет назад
This is the best thanks guys... Pleeeease do a round 2
@NeonAera
@NeonAera 8 лет назад
Is it just me or the cabinets is creating a bit of illusion of both of them sitting inside a larger big building? The whole cabinet painted black looks like there's a far away wall and handles on the cabinets look like doors and the shading effects on the wall really does mess with your eyes a little lol. Anyway, excellent interview. Thanks!
@Photologistic
@Photologistic 5 лет назад
NeonAera - I see it now. Pretty trippy. 😀
@1967davidfitness
@1967davidfitness 6 лет назад
Extreme man spreading right there! Great talk though.
@rationalrand
@rationalrand 8 лет назад
Exactly how are ketones metabolised and how much energy do they produce or (rate of production)? This answer is hard to find. While we are at it we can ask the same question for aerobic lactate metabolism.
@catherinemagee680
@catherinemagee680 7 лет назад
I have been on the keto diet for 3 weeks. I only eat once a day! I had a horrible accident back in 2000 and it ripped my lower face off. So I have real difficulty with my mouth ! at night I have to always have a sugar free cough drop in mouth?? Do you think this could be why I am not going in to Ketosis?? thanks so very much ,Catherine
@JerzeyBird
@JerzeyBird 8 лет назад
I'd love to know what the ingredients are in some of these new keto foods
@Kosh800
@Kosh800 7 лет назад
I'm on a ketogenic diet (the 70% fat one) and I have my gall bladder removed about 10 years ago. It's hit or miss sometimes with my stomach. I feel like I need to up my greens to maybe help neutralize the fairly acid heavy diet. I'm not a doctor, and you guys were speaking French to me at one point, so I'm not sure it would help with some of my gut noise or possible intestinal inflammation due to unrestricted bile release.
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Я ж идеальный?😂
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