Endochondral ossification is the primary method for bone formation in the body. This video covers the process in a step-by-step method to help you understand exactly what is happening. Video Number- Anatomy 1 -11
first of all, your drawings are cute! i've looked through enough of explaining of how ossification process forms bones, yet most of them just confuse me with tons of words that i still struggle to remember. love how you explain everything so clearly. keep it up!!
As I have commented before your videos are the best...easy to watch over a few times without the slapstick humor in other videos...your handwriting is perfect 👌
Firstly, thank you! This video is really helpful. I just wanted to know at which point the periosteum appears, and how it does so? Something to do with Perichondrium?
Hi Asher! I'm currently taking a anatomy& physiology course over the summer and I find your videos to be very helpful. Please continue making these videos and educating students about the human body!:D
So the primary ossification center of endochondral ossification was an intramembranous ossification center in the beginning, then turned to endochondral production after the gap formed by nutrients deficiency?
Hello sir, i had an small accident and 5th metacarpal was fractured, and it's just in position, doctor said, no need for k-wire , just split is enough for 6weeks. 2weeks back split is removed, now 2months completed, but fracture line still visible, how long it will take to go off crack line on x-ray, and I'm afraid of do physiotherapy, because when I'm doing physiotherapy some pain on fracture site. Give me some suggestions, please, thanks in advance....
To me it seems as though step 1 is moreso describing subperiosteal ossification as opposed to the internal endochondral ossification, anyone else agree? I'm having a hard time differentiating the two and this seemed to make that complication a bit worse for me - nonetheless, a very helpful video!
Once the chondrocytes start dying, you've mentioned that a central "clearing" begins to appear as the calcified matrix begins to deteriorate. Does all of the matrix get disintegrated? Or parts of the calcified matrix are retained and provide a scaffolding to the osteoblasts to secrete osteoid? Please help.
Hi Neely, you can think of the osteoblasts following the cartilage border as it deteriorates. This central clearing is what will become the medullary cavity, this is where we house yellow bone marrow, no osteoid type cells are there at all in the much later stages. I hope this answers your question, all the best!
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Nicely done. However, a minor correction - your sesamoid bones (such as your paired patellae) do not form via endochondral ossification. They form by intramembranous ossification.
+leapofthefrog Hi there, I believe you may have calcification confused with ossification?, which part of the video are you referring to. I'll have a quick look and try help out.
+leapofthefrog Ah yes I see where you're at :). It's definitely the chondrocytes that secrete in this phase. They are not sending a groth message as such, just releasing intracellular components that cause matrix hardening and subsequent chondrocyte death due to lack of nutrients. You can think of it as an extremely tightly regulated form of controlled cell death.
Mature cartilage is avascular, correct :). But as with any building process in the body, temporary vascularisation helps with delivery of essential components. Once the whole process is complete, the only component of the bone that has direct nerve and vascular tissue is the bone itself.
Hi. You mentoned that endochondral ossification occurs for all bones below the skull with the exception of the clavicle. But what about the ribs, scapula and bones of the pelvis?
Sou Keng Leng Hi Sou, yes the website will be back up and running very soon, however at the moment RU-vid has the majority of my lessons :). I will get back to the videos as soon as possible, just had to take a little bit of time off for a surgery. If you ever need any specific help, feel free to email me directly at asher.kidd@gmail.com Good luck with you studies!
scapula undergo intramembranous ossification, because scapula is a flat bones. other example of flat bones is ribs.you should see another of the his vid tittle intramembranous ossification
