So in the instance of testing the efficacy of a drug, purely in terms of the affects established in these graphical representations, which would be most effective? one that increases only the km vs lowering the vmax? which one would have more effect on a favorable or unfavorable outcome? (how to tell if the drug "works")?
Vmax decreasing means: the efficiency of the enzyme to convert the substrate into the product decreases. The maximum velocity or the maximum rate of the enzyme is affected (decreased) by uncompetitive and non competitive inhibition.
