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Glucose-Alanine Cycle | Cahill Cycle 

Hussain Biology
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The Glucose-Alanine Cycle also known as the alanine cycle or Cahill cycle, is the series of reactions in which amino groups and carbons from muscle are transported to the liver. It is quite similar to the Cori cycle in the cycling of nutrients between skeletal muscle and the liver. When muscles degrade amino acids for energy needs, the resulting nitrogen is transaminated to pyruvate to form alanine. This is performed by the enzyme alanine transaminase, which converts L-glutamate and pyruvate into α-ketoglutarate and L-alanine. The resulting L-alanine is shuttled to the liver where the nitrogen enters the urea cycle and the pyruvate is used to make glucose.
This Process explains why BCAA is needed during fasting , why BCAA is used as a supplement in Body Building.
The BCAA provides Proteinogenic Amino Acids which are capable of building the proteins.BCAA in humans are luceine ,isoluecine and Valine.
It is an alternate source of energy during fasting but is less efficient than Cori Cycle.

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14 окт 2024

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Комментарии : 29   
@lovemeiamlauren
@lovemeiamlauren 6 лет назад
Best video explaining the alanine cycle if you are reading the First Aid and can't understand it.
@hussainbiology
@hussainbiology 6 лет назад
Thanks Gloria for appreciating .......
@doctorofmedicine1113
@doctorofmedicine1113 6 лет назад
Sir ur videos are great really helpful . I advise all the students to watch ur video ... thanks for my quick review...
@hussainbiology
@hussainbiology 6 лет назад
Thanks Imran.....Keep sharing and supporting
@LaibaFaiz-b1v
@LaibaFaiz-b1v 2 месяца назад
Best ever❤
@ramchandrasuthar2848
@ramchandrasuthar2848 7 лет назад
Very nice
@tinayiu1273
@tinayiu1273 4 года назад
Many thanks. Just one clarification: should PLP be pyridoxal phosphate and NOT pyridixol phosphate?
@ramchandrasuthar2848
@ramchandrasuthar2848 7 лет назад
Great analysis GOD BLESS YOU
@hussainbiology
@hussainbiology 7 лет назад
Thanks Bro,,, You are always here .....I appreciate ur support...
@heroman891
@heroman891 4 года назад
Pyruvate is already in muscle then why it is not directly going to liver & forms glucose in liver & then again glucose comes to muscle & gives pyruvate by glycolysis for energy? Then why should pyruvate need to converted into alanine? Is it the cause to remove toxic NH3 from muscle?
@tinayiu1273
@tinayiu1273 4 года назад
Also I am just wondering if the aminotransferase should be Alanine transferase and NOT alinine transminase?
@ramchandrasuthar2848
@ramchandrasuthar2848 7 лет назад
Yes sir Thanks . I am seeing the signalling video Role of wnt signalling vs cancer
@hussainbiology
@hussainbiology 7 лет назад
That is great topic to work on......I will also consider it in future
@elizabethanastaspoulos7790
@elizabethanastaspoulos7790 6 лет назад
Thank you for this simplified explanation! Great job!!
@hussainbiology
@hussainbiology 6 лет назад
Thanks Elizabeth.......I am really glad by knowing that my stuff works...
@harvey2733
@harvey2733 5 лет назад
best explanation...thank you sir
@hussainbiology
@hussainbiology 4 года назад
Thanks for appreciation...Glad to know that it helps.
@annesears6757
@annesears6757 6 лет назад
This was so helpful! Thank you!
@hussainbiology
@hussainbiology 6 лет назад
Thanks Anne for appreciation...Glad to know that it helps
@deeptiriyar1808
@deeptiriyar1808 3 года назад
From where Alpha keto glutrate in liver comes.
@DrMidas02
@DrMidas02 5 лет назад
Great video
@hussainbiology
@hussainbiology 5 лет назад
Thanks buddy for appreciation
@ramchandrasuthar2848
@ramchandrasuthar2848 7 лет назад
Thanks sir
@janagiraman2874
@janagiraman2874 2 года назад
Super sir
@hussainbiology
@hussainbiology 2 года назад
thanks for appreciation..Glad it helps....✌️
@meliaa3437
@meliaa3437 7 лет назад
helpful!
@hussainbiology
@hussainbiology 7 лет назад
Thanks Melia.....Always here to help...
@mehrajd995
@mehrajd995 7 лет назад
Thanks sir, it really makes understanding easy
@aivycat285
@aivycat285 4 года назад
plsss put some subtitle... i cant barely understand the accent!!!
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