I shoot mostly heavy subs suppressed in ARs & bolt and 1680 is my fave for the biggins , yours is a light heavy weight but it’s possible to meet the requirements. ( just loud 😂)
Is 4227 strictly a boltaction/single shot load, or would it cycle in a gas gun? I have a line on a bunch of subs bullets, but I want them to run semiauto and still be subsonic.