HRQoL findings from CheckMate 8HW: nivolumab and ipilimumab in MSI-H/dMMR mCRC 

Sara Lonardi, MD, Veneto Institute of Oncology, Padua, Italy, discusses the health-related quality of life (HRQoL) outcomes from the CheckMate 8HW study (NCT04008030) of first-line nivolumab with ipilimumab versus chemotherapy in MSI-H/dMMR metastatic colorectal cancer (mCRC). Health-related quality of life (HRQoL) showed significant improvements in the checkpoint inhibitor arm. Patients on nivolumab and ipilimumab reported better Global Health Status and fewer symptoms, with a reduced risk of HRQoL deterioration. This interview took place at 2024 European Society for Medical Oncology (ESMO) Gastrointestinal Cancers Annual Congress in Munich, Germany.
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