I Took Melatonin Every Day for 3 Months and Here's What Happened 

Longevity and Anti-Aging Playlist: ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-5KNsfEBXKMg.html&ab_channel=SiimLand

I've been taking10 mg Melatonin for a long time. I sleep very soundly, but, I also look much younger than my years would indicate. (I'm almost 71 and I look like I'm in my 50s.)

Hii Siim, amazing video as always. just a question, do you also use eight sleep pod for better sleep?

Interesting experiment Siim. Did the indirect markers of inflammation -- RDW, ESR, ferritin or albumin change at all? Did the trigs/hdl ratio improve, i.e. trigs stay the same or reduce?

I’m 58 years old and have found 3mg is my sweet spot . I’ve never had a lot of problems sleeping despite being in the airline industry for 29 years . I feel a bit draggy the next morning if I go above 5mg . Sometimes my sleep times are all over the place and melatonin seems to really help me sleep better no matter what side of the clock I’m on .

Hi Siim! Thanks, this is helpful. I think you forgot to post the pdf of the supplements you take. That would be helpful is the whole protocol including at what time you take/ do what! Thanks

thanks for addressing this Sim! i don't know of many other supplements which have such conflicting opinions in the public. the only valid concern i see is the claim that any non-enzyme antioxidant taken long term can act as a pro-oxidant. I'm not sure melatonin acts in this way though. would love some clarity.

interesting topic, thank you siim. Do you have a supplement to increase deep sleep?

I’d really like to see a video on pharmaceuticals, for example LDL-c lowering drugs.

Hello, what about taking tart cherry extract instead of melatonin. Most of the melatonin supplements I find are pretty high doses. I hear some positive things about tart cherry regarding recovery and sports performance.

apparently daily doses b/w 20 and 40 mg significantly helps kill cancer

I have been taking 1 mg melatonin for a few weeks now and have been sleeping perfectly ever since. I'm in my 40s.

So, what about ROZEREM(Ramelteon)??? is that the same thing as pharmaceutical grade melatonin? I’m in the United States so things might be a little bit different here.

Siim, I love your videos. I'm a fan. But have you ever read the Matthew Walker book, "Why we Sleep". There he emphasizes about his big concern off taking melatonin for sleep. I'm sure in short term it might improve your blood markers, but aren't you worried about in long term how it could be detrimental to your own body melatonin hormonal production? I'm sorry for my english, i'm from Brazil. Love your videos man! Keep it up!

Looks like we are on the same page. I recently discovered that 1mg was too much for me as I would regularly feel groggy in the morning. Switching it to .5mg was a game changer, might have to try .3. Thanks Siim

What was that "sleep app" that you were using Siim?

I’m in my 20s and I’ve been taking 0.3 - 0.6 mg melatonin daily for close to a year and I feel like it helps me fall asleep faster, especially when I’m in a caloric deficit. I haven’t noticed any tolerance or negative side affects like grogginess. I still wake up during the night fairly consistently (usually for the restroom or between sleep cycles), but I’m able to fall back asleep without too much difficulty. I like to combine 0.3 mg short acting and 0.3 mg extended release. I take them both together 1 - 2 hours before bed.

I take melatonin for fibromyalgia insomnia every second night, along with my other sleep medications. 3mg worked as well as 10mg. They say one should take 2 weeks on, 2 weeks off, or 2 months etc.

For some reason they don't deliver to germany? Or it could be a webshop error!

my sleep notable improved after starting melatoning 10y ago never to deteriorate to the level it was at prior to melatonin.

RAY PEAT: "Okay, you mentioned the hormones estrogen and how it relates to melatonin. With increasing age, people have made a big thing of the fact that melatonin, which peaks about 3AM in everyone, that this peak is a little bit smaller in old age. But it happens that...with aging, as the thyroid decreases, the melatonin decreases, because when thyroid is active, your melatonin comes up as an antioxidant defence against that the high metabolic rate that thyroid can stimulate. So when your thyroid is low, the melatonin is low, when your thyroid is high, the melatonin is high, in a logical adaptation -- because it is an antioxidant. But the function of melatonin all by itself, when it isn't surrounded by the appropriate other conditions, melatonin, in studies done in pig tissue, by a man named (Sirotkin?), pigs are relatively close to humans in having daytime habits, night time sleep and so on, which is very important for melatonin because it's a night time dominant hormone -- in pigs, he found that melatonin suppresses progesterone and raises estrogen, and this happens to be the same thing that low thyroid does. So if the melatonin rises in proportion to your thyroid, it doesn't matter that it is having these pro-estrogen, anti-progesterone effects, because the thyroid is doing exactly the opposite to those hormones and is taking care of the situation, because thyroid gets rid of the excess estrogen while...being totally responsible for producing progesterone. But if you take melatonin out of context, as he did in the pig study, you're going to get an exactly anti-thyroid effect, deranging those hormones in the direction of stress and aging. Some of the current publicity that is used to promote the fact that melatonin is used to make you go to sleep, it happens to be also a thing that goes up during hibernation, and its function is to lower the body temperature, and remember the hospitalized patients -- the ones who had the lowest temperatures were the least likely to survive, because as the thyroid goes down and your body temperature falls, you lose a lot of your immune functions and tissue repair capacity. So lowering your body temperature does make you hibernate and it does make you sleep, but you don't want to use something out of context to force that. The studies that have been used to advocate melatonin's possibly anti-aging effect were done on mice and rats, and it turns out that they are very opposite to human beings and pigs, because they work at night in general and sleep in the daytime, and so melatonin for them has exactly the opposite meaning that it does for people and pigs. And for example, in humans and rats, melatonin raises prolactin, but in humans, prolactin knocks out progesterone production and causes infertility and stress and osteoporosis for example. But in rats, it happens, and mice, it happens...prolactin raises their progesterone, and progesterone has the pro-life, anti-aging effect. So melatonin has been confused by a lot of this rodent based research which is opposite in many ways to what it does in people and pigs." Gary Null interview 1996

I've been taking a thousand mg a day of the synthetic powdered melatonin like the health viking but don't feel any side effects. I would prefer the natural plant based Melatonin but it only comes in the prohibitively expensive capsules. Do you know a source of powder for this?

I thought you added b complex? hard to say if it was the melatonin or the b complex

Which app is used to track sleep quality???

Do you think people with autoimmune diseases should avoid melatonine if it boosts the immune system?

I do too, 10-30 mg nothing special happens, I sleep better, but also I am absolutely dependent on it.

0.3 mg was better for me too, than more. Less is more in this case I guess. (30yso)

Did your estrogen go up?

Health Viking takes 250mg afternoon under tongue and 250mg B4 bed at 65 years of age

Please review the research of Russel J. Reiter and Doris Loh before you mention the 'drawbacks' of high dose melatonin...

Large doses of Melatonin can reduce inflammation so much that you can’t sleep. This is similar to the reduction in sleep from taking the antiinflammatory Prednisone. To take advantage of the anti inflammatory effects of melatonin take it in the morning .

I take 500 mcg and it definitely helps. I also started eating a kiwi before bed but i’m not sure if it’s helping yet.

When I’m taking around 2 mg per night I always wake up after 5-6 hours , so it disrupts my sleeping cycle .

after taking it for over a 18 months(5mg) I found myself waking up always 4 hrs after taking 5mg . i stopped and sleep much better. it is a hormone and people may have different outcomes.

The only thing that makes me sleep noticeably better is intense exercise and sun exposure. When i take melatonin i seem to wake up in the middle of the night and have trouble going back to sleep, but i wonder if its the anxiety from worrying about it.

It gives me crazy headaches.

Pistachios have alot of melatonin

On days with very intense leg training (1 rep max deadlifts included), I typically have trouble to sleep at all. Melatonin saves the night, but I do need large doses, sometimes around 15mg. Subjectively I feel no bad side effects with that, but the obvious question is: does this negatively influence training adaption?

If you take a negligible quantity of anything, then I'd expect negligible results too

Measured natural melatonin levels in the blood may be far lower than what would be needed to be ingested and absorbed to make the same levels in the blood from exogenous melatonin. I know some of the supplements are meant to be sublingual and would have better absorption however many are designed to be digested and would no doubt reduce the total amount absorbed.

I'm a scientist specialist in redox signaling. I would never take any antioxidant as a supplement regularly. As you mentioned, in this aspect the dosis is the most important aspect, but only followed by the duration of the supplementation. All non-enzyme antioxidants could act as prooxidants depending on the conditions.

Yeah I’m over 50 and take just 0.3 mg melatonin per evening. Any more than that and it keeps me awake!! 😮

I take 5 mg per night. Sleep has good quality.

Some physicians are suggesting megadosing

Take 20 mg

The first few times i took Melatonin 3mg at night, it didn't seem to work for me. So i decided to try it during the daytime once. Two hours after taking it i felt the effects got super tired for the next 6 hours and could barely stay awake. Apparently when emotionally stressed you can stay awake with it but now i just time taking it 1-2 hours before i go to bed and get a guaranteed 6 hours every night when i do so. When i travel it is immensely helpful to adjust to the new time zone and a quick adjustment can be made virtually eliminating jetlag and realigning circadian rhythms rapidly.

1 take 10kg every day, never wake up again...perfect

His dosage is why he saw no impact. If he was taking Melatonin for anti-oxidant reasons, then why the hell did he take such a micro dosage of 1mg or less??? makes no sense at all.

Melatonin was too scary for me-I woke in middle of night (10mg) with seizure feeling symptoms and kept chomping my teeth together. No

You need between 5mg and 10mg to get a very good 8 hours sleep.

7:08 seems like an answer by gpt? Melatonin and most other feedback loops have nothing to do with the testes, so the text seems cued by a prompt that referenced a case in point. Gpt is vulnerable to such misdirection

Wow, I've never seen anyone with such perfect sleep. I only get on average 30 minutes deep sleep per night, and 75 minutes of REM. Some nights I don't get any deep sleep.

There are italian doctors that use melatonin as cancer fighting or preventing supplement. And as a preventive dose they recommend 20 gr 3 times per day. It is a supplement which has also adenosine and glycine in it. Of course melatonin is not the only supplement they use to prevent cancer: they also add vit d, c and other components…Sorry, I wrongly typed 20 gr instead 10mg…

Yeah well you don't have a lifelong chronic insomnia problem from a tortured childhood nor are you age 74. I take 10mgs for sleep , maybe t's too high but it works for me. Thx Siim.

I thought that taking exogenous meletonin will cause your body to decrease its natural production of the hormone. Similar to the way men taking testosterine become dependent on it as their natural , already low, production decreases even more.

Isnt it just better to get enough tryptophan

I've been taking 100mg daily ... And sleeping better than ever . New studies show it's very beneficial in many ways .

Melatonin gives me bad dreams

I take 20mg everyday

I have the feeling you cannot wait to be old so that you can experiment on the supplements for old people :D Hah, I have the "luxury" to be 10 years older than you, so I will take this advice :>

I take melatonin every night. Get 7/8 hrs of sleep.

Great content, you can take melatonin during the day for the antioxidant effect, and it does not make you sleepy during the day in fact it energizer you, I am 61 and I take 30mg most days sometimes 40mg but when it comes to bedtime I find for me 3mg good, I've tried taking high doses and yes I go to sleep quickly but can wake up three hours later fully awake and energized.

0.3 Melatonin gewd

Matt Blackburn is taking 200 mg a day.

Taken long term, i.e. years, and it can have a few adverse affects. Meditation is far better.

There is just something wrong with humans having to take drugs….I notice that no animals take drugs?

If I don't make a cocktail of supplements, I wont sleep at all.

Sounds Like You Are Not Sleeping with Woman You Love...LOL 😂😂😂

Extremely surprised that you would take melatonin

U speak too fast. Slow it down

Your LDL cholesterol is extremely high and how come for someone that is so fit?

BS.does not work

Melatonin is a waste of your money. I had to go to a sleep center and get real medicine for my sleep.

Such a shame this used to be a great Channel but it's grifting Central now

100 supplements for "longevity"?