Hei, Siim! A bit off topic, but I was wondering for some time, that considering your activity levels, which are obviously quite high, how high of a calorie deficit do you have 🤔?
I wonder if doing Z2 cardio eventually improves capacity for high intensity exercise by improving the body’s capacity to recover and deal with stress induced oxidants
I've been taking a thousand mg spread out throughout the day like the health Viking and I feel fine. But then again I don't want to decrease my sperm count so I better cut back😂
Taking that many supplements might reduce your lifespan, but there are unlimited possible negative interactions between them. This nonsense has to stop already, and we should start investing in real interventions that might cure aging
The issue with all these studies is the following: they examine a substance in isolation, whereas nutrition only works through synergy. It requires the combination of all elements to provide a biological benefit. What bothers me is that the majority of RU-vidrs either fall into the trap of repeating the same narrative, losing focus on the fact that a single ingredient can't go far..
Just checked Cronometer and my average magnesium intake from dietary sources alone is 655mg/day. Wondering if I should bother with a supplement. (And I’ve been in a 1k/day calorie deficit all month; I no doubt get more when I’m not in a fat loss phase.)
I've been taking a thousand mg a day of the synthetic powdered melatonin like the health viking but don't feel any side effects. I would prefer the natural plant based Melatonin but it only comes in the prohibitively expensive capsules. Do you know a source of powder for this?
I can do a 15 min zone 2 bike ride to work and back about 3-4 times per week. That will be about 2 hours of extra zone 2 work. Will these shorter sessions have any benefit?
Question for Siim or anyone: Does 400mg of magnesium glycinate or the Jarrow B-Right (B complex) provide any significant amounts of glycine or methyl groups. (Searched this and found nothing definitive).
I'd recommend adding sections to your video, or timestamping relevant portions in your description. It's great to incentivize people to watch the entire video, but I already trust your judgement and simply would like to skim for the list of supplements without scouring the entire 33 minutes of the video. Just a thought.
Something that I’ve always wondered. I work in construction. I spend my days lifting heavy long lengths of timber, steels, sheets or material. For a lot of the day, 5 days a week. I appreciate my job because of this. Do you think it’s necessary to still incorporate a gym routine, and lift more after a day at work? Sometimes I feel like my nervous system is so blasted from work, and I feel going and putting more pressure on it at the gym isn’t ideal. Great conversation. Thank you both
If it were beneficial to take taurine, then why isn't there stronger evidence for taking it? There is money to be made so if they can prove it they would.
I an 57 and I have less grey hair than before and have pictures fto show for it biohacking for 5 years now and obviously I didnt start with all the info I have now
Main ingredients in B.J. powder... 3:58 1. Ascorbic Acid/Corn Starch - High Insulin Spike 👎 (Insulin Spike, interferes w/ Growth Hormone.) This is not Vitamin C
there's a thing called healthy carb and when they say carbs are good doesn't mean just to eat carb and carb doesn't mean unhealthy breads and other stuff, they mean healthy carbs
Hi Everyone - Bryan Johnson here. Hey Siim - congratulations on your recent pace of aging score. A few notes. The blueprint stack is built on population level evidence, not my personal needs. For your overall score of 3.8/5, I'm going to interpret that as 5/5(!) given that everyone disagrees with everybody about anything health related. I appreciate you not being sensational. The Blueprint stack is a contender for the best in world. And as you mentioned, we publish third party lab tests and are eagerly learning. We're following the evidence and are working hard to get better. We're trying to make this journey to Don't Die easy for everyone.
Hi Bryan. I appreciate your openness and eagerness to share data. In line with your personal philosophy, do you have any plans to offer Blueprint customers a more personalized approach regarding supplementation based on lab test results, genetics, etc?
Hi Bryan, I am Dr.Zeng, MD, PhD. a longevity medical practitioner, and I agree we put a lot of emphasize evidence based medicine but ignored compliance. There are too many ingredients to take at once, I strongly suggest focus on one-drink formulation, I like the idea of only takes one drink and one pill by Novos. I am recruiting people to join the rejuvenation. Olympics by my own protocol.
I have over 1050 I am 26 eat a lot of steak. Dont exercises, just active like I have a standing desk, and I walk a lot, allways use stairs instead of elevator. Trying to never eat crap. Runing a company working everyday I wake Up untill i go to sleep. Trying to sleep for 8 hours not allways. I dont take any steroids. I drink borjomi. I fast everyday.
If you inhibit m-TOR too much you'll be frail like Dr Sinclair seems to be and miss out on the longevity benefits of a healthy and strong musculo-skeletal system.