I'm a second year biomedical science student at The university of the west of England (UWE) and your videos are helping me a LOT with my revision, you put it across so much easier than most of my lecturers and the diagrams are very helpful.... Great job!!!
I totally agree with the above comment. Uni lecturers create very unnecessary diagrams and make it look unnecessary difficult when Armando just deciphers everything so easily.
You sir,are a true LEGEND ! If all matter is explained as simple and yet,as complete - i would finish medicine for 2 and 1/2 years,instead of 6 ! Please,keep up your work,you are leaving a mark on the next generation doctors and medical workers all around !!
Hi, I'm from Brazil and I couldn't find any good explanations in portuguese about pamps and prrs! I'm so glad I found your video, it's amazing! thank you so much
This is awesome! I was in the process of commenting on your last video to ask about the difference between a PAMP and an epitope... then the playlist shuttled me along to this video before I could hit post.
Very little detail : PRR = PATTERN Recognition Receptors (not pathogen) I don't know if there is a difference but that's the word used by books. No big deal though... All the videos are awesome !!!!!!!! Thanks you so much for making Immunology so easy.
You should make the images you are drawing available. After listening to your explanation I fully understood it. It would be nice to have a picture as a reminder on my wall above my desk.
I know this is one your older videos... but we have learned compliment cascade and gone very deep into this material.... Now we start talking about PAMP and PRR and I have no idea what they are... I get to the end of your video when you are talking about secreted PRR's and they are compliment cascade!!!! LET OUT A HUGE OHHHHHHHH I GET IT.
how can the same PRR receptor, recognize both PAMP or DAMP if there are too many molecules between proteins, DNA or RNA, etc. of any microorganism and of our own DNA
Thanks for sharing, it is very educative. From the comments/ Response, it means your video was well understood, but will be glad if u can respond to the questions. It will be very good and can clarify some issues. Can u make a video on DAMP and HAMP?
Why do you draw another PRR on the lysosome membrane during the engulfing of the pathogen (when you explain the extracellular PRR). Shouldn't it just be on the macrophage membrane?
Danique Charissa I think other foreign cells can be recognised by other mechanisms, but PAMP refers to specific molecular patterns that you'd only find on pathogens, for example, double stranded RNA is a PAMP because no human would ever express double stranded RNA however many viruses do express Double stranded RNA.
Fungi have LOADS of PAMP (mannose, betaglucans...) and are eukaryotes, other than that, GREAT video! Helps me a lot studying for a selection test I'm goint to take!
i know Im randomly asking but does any of you know of a tool to log back into an instagram account?? I stupidly lost the account password. I would appreciate any tricks you can offer me
@Bryant Milan I really appreciate your reply. I got to the site through google and I'm in the hacking process atm. Takes a while so I will get back to you later with my results.
A PATHOGEN is the "entire bad thing" - the entire bacteria or virus. The PATTERN is the "part of the bad thing" - which the immune cells recognize. The immune cells don't recognize "the entire bad thing" (because that's too big.) Immune cells just recognize "part of the bad thing." So technically, it is PATTERN recognition receptor (but not that important, since this is unlikely to be a key differeniator between answer choices on a multiple choice test :)
