Like me I prefer desktops but not the size , so smaller pcs make more sense to me when you can have basically the same hardware these days in smaller builds
and set the fan at the back and the one in the air cooler the other way around to push air in instead of exausting the PSU warm air, which is also passing through the RAM
The graphics card is blocking the molex sockets on the power supply except for one row, the ones being used. It shouldn't be a problem. All the components are designed to take some heat 🔥 I have built some small builds. And from what I found is the part that fails the most from heat in any build is the wireless. If it heats up too much it can drop the connection. I put little heat sinks on the shielding now.
probably could have been better if the PSU was the other way around to vent out through the front panel mesh and the back fan pulled air in instead of exhausting it out