Smart people always are so modest. "I know some experts" while refusing to refer to himself as an expert. Seems that stupid people are quick to act like they know everything.
DreamBeatsBakery I think Einstein described a similar thing, but on the scale of humanity. As the fire of our knowledge grows larger, the things we know we don’t know increase as the area illuminated, and we also realize as the circumference of this illumination grows, how much we are in the dark.
My mom passed away from Alzheimer's in Feb..6 weeks later out of the blue my "healthy" step father died from Cruetzfedlt Jacob disease. Until that week I had never heard of it let alone that it was possible to have this human form. It hits out of the blue up to 10-15 yrs and kills almost immediately. They were deer hunters both of them. They were active and ate healthy. This yesr has changed our lives and to go back home will never have that real meaning again. I turned 43 two days ago and Im absolutely lost. I appreciate your shows Joe. Thanks for your work and the amazing guests you share with us.
@Es1911sumware That is awful. I have a freezer full of deer meat I am thinking about tossing because I did not get them tested. I also have so consumed the heart of one that was positive so that is worrying me but all I can do is move forward with the best precautions I know. From my understanding it gets in the plants as well, so even vegans are not safe.
Not mention being an engineering major and being forced to take an unnecessary and useless liberal arts class to support their program. That is just plain old, common, thievery.
If it ever comes up in your class small group discussions, this might be an interesting avenue of discussion: "There is increasing concern about the troubling possibility that blood or blood products, vaccines and other pharmaceutical products could spread the agent of variant CJD (vCJD) worldwide, especially in countries where BSE has not yet been reported. Bovine derived materials involved in the production of vaccines and other pharmaceutical products could represent a way of potential transmission of the disease. Moreover, the possibility that human blood and plasma could be a vehicle for the transmission and spread of the disease have led to a number of donor deferral policies aimed at minimizing the risk of accepting a blood donor who might be incubating the human form of BSE. In addition, blood fractionated products such as albumin are used as stabilizers in the production of vaccines and recombinant pharmaceutical products. There is, therefore, a need to ensure that regulatory authorities with limited resources can have reliable information when making their risk assessment and evaluation of product safety to prevent the transmission of TSE to human via biological and pharmaceutical products." www.who.int/bloodproducts/tse/en/
Scary shit, I've been hunting in WI for 20 years and i can remember it starting with just a blip in the middle of the state and now a good 2/3 of the state has cases of CWD. Hell, he didn't even mention that penned deer can infect wild ones just by touching noses through a fence. Scary shit...
Are you insinuating that there is a Waco, Wisconsin? Because there isn't... Also if you're not insinuating that there is a Waco, Wisconsin, I don't know why the fuck you felt it necessary to say some shit totally out of left field about an issue I suspect you know nothing about.
It's not totally unknown man. I live in South Carolina and have heard about it for years. Now given I'm a deer hunter so that's probably why. One of the many things I like about Joe is that he's a hunter/outdoorsman.
The terrifying thing about these prions are why they are so resilient. Proteins can be folded in a countless number of ways. Some of these folded states are more thermodynamically stable then others. It's not exactly the same thing, but it's similar to why carbon monoxide is so dangerous as it binds more efficiently to hemoglobin then oxygen does. In fact, part of the reason hemoglobin is so good as a transport molecule is that it's not perfect, it's not entirely stable.. it's what allows that oxygen to be let go of. Disease prions are kind of like that. The main difference being that these highly stable folded states are so stable that they can't be unfolded by normal processes and they're also so stable they can't actually be used to do anything. This basically makes them just continually build up as the body can't do anything with them and can't break them down to get rid of them. That makes them exceedingly hard to break down and gives them half-lives many times longer than normal. It's also what makes them so resistant to heat as it takes a lot more energy than normal to denature the proteins, and even more than that to destroy them. That's not the worst part though.. the worst part is that the damn things work like Ice 9 from Cat's Cradle. Every normal prion they come in contact with spontaneously misfolds itself into the new highly stable but otherwise diseased state. It's a terrifying prospect because it means that you just continually produce more of the terrible shit until you go mad and die, leaving behind a body filled with the resilient shit. It's like if Ice-Nine didn't immediately cause you to freeze solid but instead froze you so slowly that you had a few months of the crystals stabbing into your insides and into your brain before the comfort of death finally saves you from the pain.
The British have done studies of appendices and tonsil tissue in an attempt to determine exactly how extensively vCJD (Mad Cow) may have spread in England. The results were very frightening. However, no one knows how many infected humans will actually develop the disease.
Bryan Richards would make an excellent university professor! He explained things so clear and concisely with being pretentious or wordy. He's instantly likeable.
Not gonna lie...Joe has created a really cool job for himself here. He literally has interesting conversations with (mostly) interesting people from all varieties of life.
life is a fragile thing we can we wiped from this planet in the blink of an eye if anything destroy's mankind some strange disease is what my money's on.
I had a patient once with CJD. They seemed like a normal patient with dementia but they were in their late 30s or 40s. However, because i knew that they had CJD it seemed so much more eerie and odd. It was a once in a lifetime patient
That Shit was pretty big in the early 2000s in the UK and Germany. They downplayed it and it was forgotten after some time. The media coverage was pretty big back then.
For those of you saying that there isn’t any infected deer because you get your deer tested and they show no signs of infection, if you watch the whole video the biologist explains it can take years before any visible symptoms appear and not all results are accurate when look testing for CWD
@M S Possibly, especially since it's probably NOT prions causing the TSE infections, but simply a byproduct of the infection, A lot of evidence points to Spiroplasma, and it has been proven that up to 10% of cases have no prions involved. "Spiroplasma biofilm formation explains the role of these wall-less bacteria in the pathogenesis of transmissible spongiform encephalopathies (TSEs). Spiroplasma embedded in the biofilm polysaccharide matrix are markedly resistant to physical and chemical treatment, simulating the biologic properties of the TSE agent. Microcolonies of spiroplasma embedded in biofilm bound to clay are the likely mechanism of lateral transmission of scrapie in sheep and chronic wasting disease in deer via soil ingestion. Spiroplasma in biofilm bound to the stainless steel of surgical instruments may also cause iatrogenic transmission of Creutzfeldt-Jakob disease. Sessile spiroplasma in biofilm attach to the surface by curli-like fibrils, a functional amyloid that is important for spiroplasma entering cells. Curli fibers have been shown to interact with host proteins and initiate formation of a potentially toxic amyloid that multiplies by self-assembly. In TSE, this mechanism may explain how spiroplasma trigger the formation of prion amyloid." academic.oup.com/jnen/article/73/2/104/2917565
@@budshakebob3431 There are plenty of professional hunters and some countries are even using their armies for this. So insane people like Nugent aren't really the only option.
Samurai Jack Ted Nuggent is an idiot. You don't have to be a liberal vegan that's never killed a deer to understand Ted is crazy. Stop acting like you know someone you have never met and making assumptions if you don't want to look like a fool.
Yes BUT its not spread-able to humans yet but they can evolve at anytime or even some1 take 1 and experiment on it and try and spread it to humans, ones things for sure is that they wouldn't say anything imo if they didnt think itl spread to humans at a point
This happened in like 1994 when I lived in Wisconsin. They would set up orange markers on corn fields. That was a green light to put down as many as you could and DNR would burn them. My money says this was intentionally created in a lab in America. They just created GMO mosquitoes that are infused with some biological gene to eradicate themselves.
Depends on the species. For mammals, yes, it is usually bad. But for fish and reptiles, it is a good thing and helps the strongest of the young to grow faster.
I am in Wisconsin as well. I don't know if god is real, but if god was real this is what would happen when sick humans go around bragging about the size of deer they murdered. Deer are one of the most beautiful and peaceful animals.
I'm in NJ near Easton PA and I'm near a lot of hunting land. Tonight, my brother mentioned this condition after there was a deer right in front of our house look at the outdoor cat. It wasn't scared at all and we were talking on the porch 8-12ft away. I spoke up a bit and it still didn't move. I do remember seeing deer doing this last year too!
when CWD passes to people, they will say-"this is a new disease, we did not know about it and did not assume that this would happen, it is impossible!" But in fact, they could have prevented it 5 years ago.
Living in Wisconsin I can say that all my friends who hunt say this a really bad problem that could boil over due to the insane amount of deer here in Wisconsin.
You need wolves and Coyotes. Here in CT the deer were out of control and everyone complained. The coyotes came in and have done an excellent job of culling. Now people complain about the coyotes. You cant win
benjovi55 ... we have a few counties affected here in WV too. The only answer is to offer mass hunting and tagging these deer. The transmitting of this disease will get worse until we take some drastic steps to cull the population.
Gotta thank Joe for bringing this critically important topic to his worldwide platform. CWD has been on the DNR'S radar for at least 20 years. There are new cases of discovered every year but we've been able to for the most part keep it out of the northern herd here in WI. It's still something that is in the back of all of our minds here who are deer hunters.
This is one of those things that is technically "possible" to fix, but would require so much perfect planning, fencing, culling, and control over every deer it is essentially impossible
They keep bringing up possible human transition, but I’m more interested in how or if it can affect predators that hunt these deer, or possibly other herbivores that come in contact with infected waste or even a water supply.
i'm always surprised how much Joe is able to follow intellectual discussions in depth and he always asks great questions; the exact same ones i want to ask while listening (as a relaxed audience member. idk if i could do that on the spot like he)...
Love the diverse and informative topics...I've watched a bunch of your shows but I subscribed because of this one...This is better public service then most news stations. Taking the time to cover the subject so that people can make informed decisions on how this matters to them. LOVE IT!
so Umbrella will come to pass through the merging of these corporations feeding cattle to cattle...none of which will stop...long after this thing jumps species to humans...
"When Ted Nugent was on the podcast he downplayed the consequences and effects of something called CWD" You can always count on Ted Nugent for his extraordinary insights.....
@@joblo1978 Sure thing bud. Next time don't lead with this trash "Right. Because all scientists agree, all scientists are never wrong, biased, or greedy, and science never refines itself, And, unless you’re a scientist, you know nothing. Not all info on CWD from scientists corroborates."
Dam dude you a sheep willing to follow what ever some with a lab coat will tell you. Yeah that right don’t think and put in your own research and experiments just follow the trend.
@@BryanTheHunter Molecular biologist research chemist Ted is not. CWD is like mad cow disease on steroids and would cause non familial SCJD in humans. Dont listen to Ted, hes cabal and his job is to downplay CWD so a bunch of second amendment supporters get killed by this disease. Ted's a fucking idiot, not a scientist.
We had numerous white tail die from this the last two years in Nebraska. It's weird how the infected deer act as well. Lethargic, not afraid of people and act almost as if they are just walking around without a rhyme or reason. Scary stuff makes us hunters think about how our meat may be infected around the area.
UncleRucus I honestly don’t really give a shit 😂 I just thought his response was funny cause it was something a 12 year old would put. This disease has been around for a long time and in my area it’s been here for a long time. So it doesn’t phase me tbh
Reindeer herds range from Lapland in Norway, Sweden, Finland, and through Northern Siberia. The loss of those herds would be catastrophic to the herders who depend on them for food, shelter, and clothing.
We still feed the rendered cow parts to the other cows. And don't think you get off the hook with 'free range' either. Cow feed without rendered cow in it is more expensive so almost no one uses it. This could explain the growing number of dementia and Alzheimer's we are seeing. Like everyone grandparents have that shit, sadly including my own. Its Horrific. If we are going through this to save 4$ a bag on cow feed its not worth it.
Thanks for the great presentation. In 2002 CWD broke out less than a mile from my family’s tree farm in South-West Wisconsin. We have been working with both state and federal agencies regarding this problem ever since. While there is no doubt it is a problem, it is not the disaster it was first claimed to be. The epidemiological models that predicted a collapse of deer populations not only in Wisconsin, but nationwide were a bit exaggerated to say the least. As we approach 20 years experience with this disease we are seeing the emergence of animals that are more tolerant of the ravages of this disease. This was to be expected. The differential survival of more resistant animals propagated their genes in greater numbers at the expense of the most susceptible. This has resulted in a drift toward a population of more disease tolerant animals. This is not to be confused with resistance or immunity. The animals still contract the disease and die from its effects but at increasingly older ages. Considering the average male whitetail deer has a natural life span of 6-7 years in the wild, even a modest toleration of the disease mitigates its effect on reproduction rates fairly quickly. Wyoming has seen a similar trend over the years as well. Still the captive animal farms are the primary risk perpetuation this disease. Montana took the steps early on to outlaw the farming of game animals and it worked fairly well, yet we are now seeing the first cases moving up from Wyoming.
My mother died of Creutzfekdt-Jacob Disease, sudden onset, in 2009. It's a horrific way to watch someone waste away. TSE, the prion's in the brain fold, which is sudden and fatal.
As I posted above, I have a friend that died of Creutzfekdt-Jacob Disease last year and I have a client who also has a friend that recently died of this as well. What are the odds of it only killing 300 people in the US a year. Im thinking its much more prevalent. We are not being told because no one really knows how is is contracted. Because it may take 40 years to kill a human I feel there may be no urgency to find a cure. One thing for sure, I will never eat deer after hearing this podcast.
Read Deadly Feasts, it explains everything he's talking about. Fore tribe in Palau New Guinea were cannibals, which is where first cases of Kuru occurred. Kuru means "laughing disease", which is what my momma did; she had a few days of uncontrollable laughing. This disease is horrific.
Azzury Street you're wrong. The women of the Fore tribe were starved by their husbands, so they had to resort to the eating meats of the other females who died. The vital organs were choice, fatty meats, and unfortunately the brain is where Kuru (CJD) resides. You think you're being funny, but you're talking out your ass. I sure hope that you or a loved one never dies from this horrific disease.
Hillary Clinton also has Kuru, laughing fits and a gaping hole in her tongue combined with all her connections to human traffickers and cannibals enthusiasts/pedophiles
Ramon Almeida we donated her brain to the Prion Center in Cleveland Ohio, which was THE only was to 100% confirm CJD, and which type. Hers was Sudden Onset, which had been laying dormant for years. Thank God it was not familial or from eating wild game, or mad cow disease.
I used to hunt antelope in Alberta 20 years ago. The wildlife conservation officers would check recent kills for visual signs of wasting disease in these populations also. It was a relatively new phenomenon 5-10 years prior to the first observed cases. At that time it was suspected to be due to a lack of natural predation and a reduction in wilderness areas for food sources. However, indigenous populations in southern Alberta used to tell stories of warriors that developed a "madness" from eating to many Buffalo skulls; which was a prized food source due it being a very rich source of fat and protein. So, BSE may have been present in the environment long before cattle were brought to North America. My understanding of the pryon is that it can survive in range of 100's to 1000's of years.
Well I heard an interesting tidbit out here. I heard that bone meal was brought here from Britain just before they discovered their mad cow problem, and gave it to cattle here!
All I will say is this. I worked with a PhD researcher specialized in CWD and worked exclusively in CWD research. He contracted CJD, the human version of CWD. Quite the coincidence as he had no other exposure.
@@howardman3926 no its not. rates are steadily increasing. could be due to better ascertainment/ diagnosis. and there are case clusters in different parts of the world. public health lies when it says that its a consistent 1-2 in a million disease.
Very smart dude... I like how he even took the time to explain to explain why to “prion” is pronounced that way... Very soothing voice delivering horrific news...
Phenomenal segment Joe!! Educated me to the tune of about 95% more of an understanding of CWD than whats really out there or what wants to be known either by design or otherwise. After watching the full #1154 in its entirety, left me with an interesting question; Maybe you can answer or if you have any suggestions on how to contact Mr. Richards? Both he and Mr. Duren made several points to suggest the importance of proper disposal of "bones". Whether it be to a proper landfill or leaving on a property already infected by the disease. My question; where do antlers play a role in this? I mean do I potentially have CWD Prions in my living room? Further thinking, we buy our dogs "top of the line" U.S. made and guaranteed Elk and Deer antlers for chews. Just interesting to wonder if there is potential risk here. Anyways I thought these were at least interesting observations relating to the disposal of an infected animal's bones as potential vessels to carry and pass the disease! Let me know if you have any light to shed. Regards.
lompockid we need to bring deer mental health awareness to the public as suicide rates are high. Only logical explanation as to why there are so many deers jumping infront of cars
Yeah right, you pussies can't survive without delivery food and video games. Your not killing shit cause all your guns are downloaded. You guys are the first to to die and have your resources taken.
Es1911sumware It appears that you are well educated and have a personal experience with Jacobs desease, that’s great. My point was that the biologist clearly explained what CWD is and capable of doing. I am coming to you from an academia point of view. And no, I will eat the deer, always have.
Es1911sumware clearly you are biased because of personal experience, I get it. But the I formation the biologist put out about the actual desease is accurate.
Es1911sumware how are you able to determine that they are lobbying of 1 hr of pod cast? Seems like you have them beat on Knowledge, do you have your own podcast I can listen to?
@@Essumwarewhy are you convinced it isnt happening ? I dont trust the government, but how much profit would these guys be making off of this lmfao seems like a super random thing to have a conspiracy over.
im a bald biologist from the institute of bald sciences in madagascar, im not bald myself, what that means is that i study bald people for a living, their habitats, everything about them, check this out: it has been proven that when in inminent danger, bald people sometimes use the reflection of the sun on their heads to blind their enemies and gain a situational advantage also called gaining a bald initiative also flies never land on their heads, ever, and judging their age is at least 70% harder than other groups of people more public money should go towards the study of bald people, they are trully an amazing bunch
I work as a disease investigator and this scares the shyt out of me. Your'e telling me an infected deer that's incubating can test negative but still transmit infection for 3 to 6 months? Man thats worse than syphilis lmao
Joe showing great interview skills here. he obviously recognizes this expert knows his shit inside and out. Joe asks a few guiding questions but lets him drop knowledge like class was in session. this is why Joe has a wealth of knowledge. he LISTENS when someone has valuable insight. more hosts need to do this.
I have a farm in Missouri that had cwd, our neighbor was a trophy farm. Cwd is similar to a forest fire. It can devastate the population, but the population will rebound. Dnr will test your deer for cwd, and usually have testing stations around for hunting season.
its been common for whitetail deer in my area to herd up with 30-60 units. I have lived near the headwaters of the Mississippi for over 40 yrs. this brain eating disease was weaponized like lymes and the lone star tick's vegetarian disease.
My family has a whitetail deer farm in western iowa where there are no documented cases. My grandfather has had every deer that dies tested since 2000 and not one has had the disease but I'm starting to worry with the spread lol
@Christian Slater or maybe having learned some useful critical thinking skills in the field they found it interesting and attributed that interest to said learned skills?
