It's actually cool as fuck how Ishmael changes her catchphrase after you beat Canto 5, because she could let go of her past, and doesn't care about "that bastard" anymore Even though that bastard is still alive, funnily enough, and will probably make a comeback some time in future
that's probably one of his alternate EGOs the basic one (zayin tier) is called "Suddenly, One Day" and it makes his bug arm an actual arm and really big and it can randomly inflict a status effect (either bleed, burn, rupture, sinking or tremor)