Lose Your Gut (Pot Belly) with these Strategies 

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Lose Your Gut (Pot Belly) with these Strategies - Thomas DeLauer
Fasting
Study from Nature Communications found that fasting preferentially burns visceral fat
Fasting upregulates miR-133a, which inhibits PRDM16, and that reduces thermogenesis in Subc WAT and drives the transition from Sub to Visceral fat**
Visceral fat is preferentially oxidized as it can drain directly into the portal circulation and appears to be more efficient at meeting energy needs compared with the relatively externally located subcutaneous fat
Visceral is more vascular and contains a higher % of large adipocytes plus having more glucocorticoid and androgen receptors than subcutaneous
www.nature.com/articles/ncomm...
Estrogen
Boron
Boron inhibits SHBG, freeing up testosterone, and this increase in T results in the decrease of E2
Additionally, boron can:
Boost magnesium absorption
Reduce levels of inflammatory biomarkers, such as high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor α (TNF-α)
Raise levels of antioxidant enzymes, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase
DIM
DIM is a naturally occurring byproduct of indole-3-carbinol (IC3), and IC3 itself is a byproduct of glucosinolate glucobrassicin, which is a compound found in cruciferous veggies, such as: broccoli, cauliflower, cabbage, Brussels sprouts, and kale
In particular, IC3 helps the liver to metabolize estrogen more efficiently via upregulating the CYP1A2 enzyme (CYP1A2 is an enzyme that helps to break down toxins in our bodies)
It also simultaneously converts strong estrogen molecules into less potent ones (via downregulation of the CYPB1B enzyme and upregulation of CYP1A2 enzyme) - results in reduced estrogen levels and a more favorable estradiol/estrone ratio
DIM and its precursor, I3C, suppress adipogenesis, which is the formation of new fat cells
Cortisol
Salt
A lack of sodium causes the brain to send signals to the adrenal gland to increase the release of hormones responsible for water balance (aldosterone & vasopressin) - cortisol is released alongside these hormones
Magnesium
Magnesium deficiency also causes upregulation of the HPA (Hypothalamic-Pituitary-Adrenal) axis which leads to anxiety-like behavior in mice. The HPA axis is responsible for influencing production of the stress hormone cortisol.
Also inhibits the release of excitatory neurotransmitters and also acts as a voltage-gated antagonist at the glutamate, N-methyl-D- aspartate (NMDA) receptor
www.ncbi.nlm.nih.gov/books/NB...
Tea for Coffee
Caffeine does cause increases in cortisol, so reducing total caffeine intake may be favorable as well
Liver
Turmeric
Curcumin, one of the active ingredients in turmeric is believed to communicate with liver cells to produce more LDL receptors. Due to increase in receptors, more cholesterol is cleared from our body
Foods High in Chlorophyll (gourd, arugula, dandelion greens, spinach)
Chlorophyll is literally the blood of plants - its chemical structure resembles that of hemin, which combines with protein to form hemoglobin in the human bloodstream
Chlorophyll has proven beneficial to increase the red blood cell count in humans - red blood cells carry oxygen to the tissues
An abundance of oxygen and healthy flow of blood encourages the body to get rid of harmful impurities and toxins - also helps as it chelates to heavy metals
Milk Thistle
The active ingredient in milk thistle, silymarin, creates a detoxifying effect in the body and in the liver as it acts as an antioxidant by reducing free radical production
Silymarin reduces free radical production and lipid peroxidation, has antifibrotic activity and may acts as a toxin blockade agent by inhibiting the binding of toxins to the hepatocyte cell membrane receptors
Pancreas
Study from Diabetologia found that just two weeks of exercise improves beta cell function and reduces pancreatic fat in adults with type 2 diabetes or prediabetes
Found that this short-term training particularly reduced ectopic fat (fat that accumulates in abnormal parts of the body) in the pancreas
Additional Resources
link.springer.com/article/10....
www.diabetes.co.uk/news/2018/...
www.sciencedaily.com/releases...
stm.sciencemag.org/content/2/...